No abstract available.
Contracture*

No abstract available.
Fingers*

Remarkable improvement in control of malignant tumor was achieved by combined surgery and postoperative radiation therapy. In Past, radiation therapy had been recommended after 4-6 weeks from operation because of worry about increased complication rate of surgical wound by post-operative irradiation. Nowadays, early surgical extirpation and early post-operative irradiation is recommended for better therapeutic effect. To evaluate the relationship between surgery-radiation interval and healing of surgical wound, an experimental study was undertaken using a total of 132 mice. A single dose of 2000 rads irradiation was delivered immediate after and on 1,3,5,10,14days after incision and suture on the skin of hind limbs of mice. Tensile strengths of the wounds were measured after removal of stitches on 1st, 3rd, 5th, 7th, 10th, 14th and 21st post-operative days. The results are summarized as follows; 1. Wound healing was delayed by irradiation delivered within 3 days from operation. 2. No significant delay of wound healing was observed by irradiation on 5 or more days after operation. 3. Normal wound strength was attained at 21st post-operative day in any surgery-radiation interval. 4. More severe delay of wound healing by irradiation at 24 hrs after operation than by immediate post-operative irradiation although statistical significance is not confirmed. In conclusion, early post-operative irradiation delays healing of the surgical wound though ultimately tensile strength reaches the value of non-irradiated wound.
Animals ; Extremities ; Mice ; Radiation Effects ; Skin ; Sutures ; Tensile Strength ; Wound Healing ; Wounds and Injuries

Cerebral cysticercosis may produce many complications and various types of tissue reactions to the parenchyma of the brain. The purpose of the present investigation was to study the nature of the reactions of the brain tissue responding to a direct contract with the fluid contents of cysticercus cyst. The experiments were performed in 15 albino rats in which the brain lesions were made on the frontal region by injecting the fluid contents which was obtained from subcutaneous nodules of human patient with cysticercosis. The fluid contents, 0.5 ml for each animal, was injected with 26 gauge hypodermal needle into the left cerebral hemisphere beneath the cortex for experimental group, and same amount of normal saline into the right hemisphere indentical to the region of the left for the control group. Histopathological studies were carried out on the brain lesions at interval of 3 days, 7 days and 15 days following injection of the contents and normal saline. Findings of generalized and regional edema of the brain were observed in varying degrees, which were evident and severe in 3-day and 7-day experimental groups and decreasing in severity thereafter. In the group of normal saline injection, the microscopic findings of the lesions were mainly of a mild inflammatory reactions with scattered fibroblast or condensation of the nervous tissue. In 3-day experimental group, there were pleomorphic infiltration of neutrophils and histiocytes. In 7-day experimental group, there were prominent cellular reaction, gliosis and vascular proliferation more than those observed in 3-day group. In 15-day experimental group, inflammatory cells and gliosis were reduced in number and degree, but definitive granuloma with proliferation of vascular fibroblast in its outer layer was developed.
Animals ; Brain ; Cerebrum ; Cysticercosis* ; Cysticercus ; Edema ; Fibroblasts ; Gliosis ; Granuloma ; Histiocytes ; Humans ; Needles ; Neutrophils ; Rats

Authors report a rare case of dumb-bell ganglioneuroma in the neck of a four-year-old child. The mass was in the left anterior neck and grew slowly over several years. Neurological deficits. Cervical spine X-rays showed an enlargement of intervertebral foramens and widening of interpedicular distances at lower cervical level. The surgery was performed at different stages for a total removal of the intra and extraspinal masses.
Child* ; Ganglioneuroma* ; Humans ; Neck* ; Spine

A rare case of a giant-celled glioblastoma arised from the intracranial portion of the right frontal base is presented. Clinical presentation was that of increased intracranial pressure with bilateral optic papilledema. Skull X-rays showed an erosion of the right orbital roof. Right carotid angiogram confirmed the presence of a tumor in the frontal base.
Cerebrum* ; Glioblastoma* ; Intracranial Pressure ; Orbit ; Papilledema ; Skull

Cerebral cysticercosis, is unfortunately, a frequent disease in Korea. Cysticercosis in man is exclusively due to the development of Taenia solium larvae, called Cysticercus cellulosae, which is a frequent parasite in the pig. The clinical symptoms which are varied and similar to those of any other tumor of the brain, are depent on the location, number of parasite, intensity of infestation and susceptibility of the host. The headache, vertigo, nausea and vomiting, appearing periodically, and chiefly after a rapid change in the position of the head, were indicative of a cysticercus lying free in the fourth ventricle. We have recently experienced a case of cerebral cysticercosis which involved the 4th ventricle. A forty-year-old man was aditted to the Department of Neurosurgery, College of Medicine, Korea University in June, 1978 because of severe headache, repeated vomiting and diplopia which progressed gradually for two months previous to admission. On admission, there were no specific localizing and lateralizing neurological abnormalities except for signs of mild cerebellar dysfunction and signs of increased intracranial pressure accompanying with bilateral optic papilledema. Conray ventriculogram disclosed the dilation of proximal portion of the 4 th ventricle and smoothly rounded central filling defect of the 4 th ventricle. Brain C-T Scan demonstrated the marked dilation of 4 th ventricle in found shape without evidence of midline shift or compression. This enlarged 4 th ventricle with water density was shown no evidence of the contrast enhancement. Suboccipital craniectomy was performed and a cystic mass was removed from the fourth ventricle. Pathological diagnosis of the specimen was cysticercosis. Following surgery, the patient's symptoms cleared up and neurological deficits and papilledema improved gradually.
Brain ; Cerebellar Diseases ; Cysticercosis* ; Cysticercus ; Deception ; Diagnosis ; Diplopia ; Fourth Ventricle ; Head ; Headache ; Intracranial Pressure ; Korea ; Larva ; Nausea ; Neurosurgery ; Papilledema ; Parasites ; Taenia solium ; Vertigo ; Vomiting ; Water

A case of the narrow lumbar spinal canal was reported in which a lumbar disc herniation was coexisted at L3-L4 interspace. The patient was a 58-year-old male whose chief complaint was pain in the low back and in both legs which was intermittent in occurrence and alternative from side to side. The symptoms lated for about 7 years prior to this admission to hospital and it was initiated and aggravated by standing for minutes or walking and especially by extention of low back. No significant neurological deficits were detected in neurological examination except for signs of single nerve root compression from which L3-L4 disc herniation was suspected. Findings of simple lumbar spine radiograms and myelograms were compatible with those of narrowed spinal canal. Complete bilateral laminectomy of lumbar spine sparing articular facets were performed to get freedom of neural element or structure in the spinal canal from pressure. Hypertrophied ligamentum flavum, thickened laminae and protrusion of disc at L3-L4 interspace were the findings observed in the surgical operation. The patient became asymptomatic after the surgery.
Freedom ; Humans ; Laminectomy ; Leg ; Ligamentum Flavum ; Male ; Middle Aged ; Neurologic Examination ; Radiculopathy ; Spinal Canal* ; Spine ; Walking

An intracranial aneurysm usually bleeds into the subarachnoid space. In addition, it may also rupture into the subdural space or into the brain, or both. The management mortality rate for ruptured intracranial aneurysm increases in the cases accompanying large intracranial hematoma. Several previous reports have considered the timing of operation for ruptured intracranial aneurysms accompanying large intracranial hematomas in relation to postoperative results. Generally, all patients with large intracranial hematoma should have the hematoma removed promptly even though definitive surgery for the aneurysm is to be delayed. But determination of the optimal time for surgical intervention of ruptured intracranial aneurysm accompanying large intracranial hematoma depends entirely on neurosurgeon's experience and decision. Our three cases of ruptured intracranial aneurysms accompanying large intracranial hematomas are reported and discussed for timing of surgical interventions.
Aneurysm ; Brain ; Hematoma* ; Humans ; Intracranial Aneurysm* ; Mortality ; Rupture ; Subarachnoid Space ; Subdural Space

We have recently experienced a case of malignant schwannoma in the right ulnar nerve. A 17 years old male underwent a surgery with a total removal of malignant schwannoma of the right ulnar nerve in the elbow. The tumor mass was walnut size with infiltration to the adjacent structures. The pathological findings show the pattern of interlacing bundles of long spindle cells, plumper hypochromatic elongated or serpentile and eosinophilic nuclei with process and frequent mitosis, loss of cellular polarity and polymorphism can be seen. Pathological diagnosis was malignant schwannoma. Approximately 4 months later his initial operation, the tumor recurred at right elbow and axillary region and removed without any proper treatment.
Adolescent ; Diagnosis ; Elbow ; Eosinophils ; Humans ; Juglans ; Male ; Mitosis ; Neurilemmoma* ; Ulnar Nerve*