1.Surgical treatment of the bilateral facial nerve paralysis combined with temporal bone fracture.
Won Sang LEE ; Jang Hoon CHI ; Jeong Hwan LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(3):506-511
No abstract available.
Facial Nerve*
;
Paralysis*
;
Temporal Bone*
2.Gold weight implantation for the patient with facial paralysis.
Won Sang LEE ; Jong Hun LEE ; Jang Hoon CHI ; Sang Yeul LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):656-662
No abstract available.
Facial Paralysis*
;
Humans
3.Modified Trajectory of C2 Laminar Screw - Double Bicortical Purchase of the Inferiorly Crossing Screw.
Woo Tack RHEE ; Seung Hoon YOU ; Yeon Gyu JANG ; Sang Youl LEE
Journal of Korean Neurosurgical Society 2008;43(2):119-122
The crossing laminar screw fixation might be the most recently developed approach among various fixation techniques for C2. The new construct has stability comparable to transarticular or transpedicular screw fixation without risk of vertebral artery injury. Quantitative anatomical studies about C2 vertebra suggest significant variation in the thickness of C2 lamina as well as cross sectional area of junction of lamina and spinous process. We present an elderly patient who underwent an occipito-cervical stabilization incorporating crossed C2 laminar screw fixation. We preoperatively recognized that she had low profiles of C2 lamina, and thus made a modification of trajectory for the inferiorly crossing screw. We introduce a simple modification of crossing C2 laminar screw technique to improve stability in patients with low laminar profiles.
Aged
;
Humans
;
Spine
;
Vertebral Artery
4.Phospholipase A2 Contributes to Hemorrhage-induced Acute Lung Injury Through Neutrophilic Respiratory Burst.
Yoo Suck JANG ; Seong Eun KIM ; Sang Hoon JHEON ; Tae Rim SHIN ; Young Man LEE
Tuberculosis and Respiratory Diseases 2001;51(6):503-516
BACKGROUND: The present study was carried out in association with neutrophilic respiratory burst in the lung in order to clarify the pathogenesis of acute respiratory distress syndrome(ARDS) following acute severe hemorrhage. Because oxidative stress has been suggested as one of the principal factors causing tissue injury, the role of free radicals from neutrophils was assessed in acute hemorrhage-induced lung injury. METHOD: In Sprague-Dawley rats, hemorrhagic shock was induced by withdrawing blood(20 ml/kg of B.W) for 5 min and the hypotensive state was sustained for 60 min. To determine the mechanism and role of oxidative stress associated with phospholipase A2(PLA2) by neutrophils, the level of lung leakage, pulmonary myeloperoxidase(MPO), and the pulmonary PLA2 were measured. In addition, the production of free radicals was assessed in isolated neutrophils by cytochemical electron microscopy in the lung. RESULTS: In hypotensive shock-induced acute lung injury, the pulmonary MPO, the level of lung leakage and the production of free radicals were higher. The inhibition of PLA2 with mepacrine decreased the pulmonary MPO, level of lung leakage and the production of free radicals from neutrophils. CONCLUSION: A. neutrophilic respiratory burst is responsible for the oxidative stress causing acute lung injury followed by acute, severe hemorrhage. PLA2 activation is the principal cause of this oxidative stress.
Acute Lung Injury*
;
Free Radicals
;
Hemorrhage
;
Lung
;
Lung Injury
;
Microscopy, Electron
;
Neutrophils*
;
Oxidative Stress
;
Phospholipases A2*
;
Phospholipases*
;
Quinacrine
;
Rats, Sprague-Dawley
;
Respiratory Burst*
;
Shock, Hemorrhagic
5.The Structural Properties of Israeli Carp ( Cyprinus carpio L. ) Immunoglobulin.
Sang Hoon CHOI ; Jong Kyu WOO ; Yong Suk JANG ; Chan Ho OH
Korean Journal of Immunology 1999;21(1):85-92
Serum immunoglobulins from Israeli carp (I. carp) were purified using affinity chromatography. Fish were immunized with purified mouse IgG, and the specific fish antibodies purified from the immune serum on a mouse IgG-immobilized agarose gel. Rabbit anti-carp Ig (Raclg) antibodies were produced following hyperimmunization with mlgG specific I. Carp Ab. SDS-PAGE analysis under reducing condition showed that I. carp Ig (clg) were composed of two u-like heavy chains with about 82 and 50 kD, respectively and one light chain with about 25 kD. On immunoblotting analysis, however, Raclg failed to react with light chain. When both protein A and protein G purified normal clg were compared with mlgG specific clg, no significant structural differences among them were observed. To investigate if there is any homology between other fish Ig molecules, cross-reactivity of Raclg against Ig molecules from 6 different fish sera and mouse control serum was checked on immunoblotting analysis. As a result, Raclg responded to only carp and tilapia Ig molecules, indicating that both tilapia and carp are very closely associated, especially, in the genetic basis of immunoglobulin structure. In flow cytometry study, Raclg appeared to recognize 45.8% of carp Ig+, 14.5% of catfish Ig+ and <5% of tilapia Ig+ cells. The result suggest the heterogeniety between receptor immunoglobulins on B-like lymphocytes and soluble immunoglobulins in serum. It is crucial to obtain pure fish immunoglobulins to produce reagent antibodies as tools for the study of their specific immune response.
Animals
;
Antibodies
;
Carps*
;
Catfishes
;
Chromatography, Affinity
;
Electrophoresis, Polyacrylamide Gel
;
Flow Cytometry
;
Immunoblotting
;
Immunoglobulin G
;
Immunoglobulins*
;
Lymphocytes
;
Mice
;
Sepharose
;
Staphylococcal Protein A
;
Tilapia
6.Malignant Lymphoma of Mucosa-associated Lymphoid Tissue Arising in the Conjunctiva.
Tae Kyung KIM ; Jang Oh KIM ; Sang Won KIM ; Hoon Kyu OH ; Jae Bok PARK
Annals of Dermatology 1995;7(3):273-277
We report two cases of malignant lymphoma of mucosa-associated lymphoid tissue arising in the conjunctiva. Case 1, an 18-year-old girl, showed her left lower conjunctival swelling for four months and Case 2, a 29-year-old man, showed similar lesions on both his eyes for one year. Histologically, both cases revealed monomorphous dense lymphoid infiltrates invading the overlying conjunctival epithelium with diffuse patterns. The infiltrates were composed of small lymphocytes admixed with centrocyte-like cells within the conjunctival epithelium and stroma in association with B-cell lineage. No relapse was noted during the period of about 1½ years follow-up in case 1 treated by local excision only and in the follow-up period of 2 months in case 2 treated by local excision and subsequent chemotherapy.
Adolescent
;
Adult
;
B-Lymphocytes
;
Conjunctiva*
;
Drug Therapy
;
Epithelium
;
Female
;
Follow-Up Studies
;
Humans
;
Lymphocytes
;
Lymphoid Tissue*
;
Lymphoma*
;
Recurrence
7.Surgical treatment of facial nerve paralysis via middle cranialfossa approach.
Won Sang LEE ; Jang Hoon CHI ; Hong Joon PARK ; Jae Young KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):56-66
No abstract available.
Facial Nerve*
;
Paralysis*
8.A study on the hemolytic properties of Prevotella nigrescens.
Ju Seok KWAK ; Hoon Sang JANG ; Seok Woo JANG ; Su Jong LEE ; Yong Wook YU ; Kyung San MIN
Journal of Korean Academy of Conservative Dentistry 2005;30(4):335-343
Hemolytic property is a specific feature of bacteria to obtain iron which is essential for its survival in host tissues. Therefore, it is thought to be one of several factors of virulence. The purpose of this study was to investigate the hemolytic properties of Prevotella nigrescens isolated from the teeth diagnosed as pulp necrosis and apical periodontitis under the presence of hemolysin inhibitors such as NaN3 and dithiothreitol, heat, various pH and cultural conditions. The results were as follows; 1. Clinically isolated P. nigrescens strains and standard P. nigrscens ATCC 33563 showed hemolytic activity. 2. P. nigrescens showed higher hemolytic activity against human erythrocytes than sheep or horse erythrocytes. 3. NaN3 and dithiothreitol (DTT) reduced the hemolytic activity of P. nigrescens in a dose dependent manner (p < 0.05). 4. Optimal pH for the maximum hemolytic activity of P. nigrescens was 4.0 and the hemolysin was stable under the 50degrees C, but the hemolytic activity was significantly decreased at 95degrees C. 5. P. nigrescens cultured in 10% CO2 condition showed higher hemolytic activity than the bacteria cultured in the anaerobic condition.
Bacteria
;
Dental Pulp Necrosis
;
Dithiothreitol
;
Erythrocytes
;
Horses
;
Hot Temperature
;
Humans
;
Hydrogen-Ion Concentration
;
Iron
;
Periapical Periodontitis
;
Prevotella nigrescens*
;
Prevotella*
;
Sheep
;
Sodium Azide
;
Tooth
;
Virulence
9.The bronchoalveolar lavage fluid cell analysis with normal lung and unaffected side lung of patients with minor symptoms or radiologic abnormalities.
Byung Il KIM ; Chul Ho CHO ; Shin Wook KANG ; Seon Hee CHEON ; Sang Ho JANG ; Jang Hoon LEE ; Joon CHANG ; Sung Kyu KIM ; Won Young LEE
Tuberculosis and Respiratory Diseases 1991;38(2):155-163
No abstract available.
Bronchoalveolar Lavage Fluid*
;
Bronchoalveolar Lavage*
;
Humans
;
Lung*
10.Effect of hemodialysis and continuous ambulatory peritoneal dialysis on pharmacokinetics of carumonam.
Dong Seok YIM ; Sang Goo SHIN ; Jong Tae CHO ; Jin Suk HAN ; Kyung Hoon LEE ; In Jin JANG
Korean Journal of Nephrology 1993;12(1):27-35
No abstract available.
Peritoneal Dialysis, Continuous Ambulatory*
;
Pharmacokinetics*
;
Renal Dialysis*