No abstract available.
Anemia, Aplastic*

No abstract available.
Diabetic Retinopathy* ; Retina*

Rotator cuff tear is a common reason for shoulder pain. Although the surgical technique of rotator cuff repair is developing, high retear rate requires additional supplementary methods. Among these supplementary methods, as a kind of biologic augmentation, platelet-rich plasma (PRP) has been spotlighted and has recently been studied by many researchers. PRP, a concentrate of platelet extract obtained from whole blood, contains numerous growth factors. As this is known to play an important role in the tissue recovery process, it had been used for research in a variety of fields including orthopedics. Use of PRP has been attempted in surgical treatments of rotator cuff tear for better results; however, only a few large-scale research studies on the effect of PRP have been reported. Clinical results of each study are also variable. Therefore research using large-scale randomized, double-blind trials should be conducted in order to prove the application range, safety, and clinical effects of PRP.
Blood Platelets ; Intercellular Signaling Peptides and Proteins ; Orthopedics ; Platelet-Rich Plasma* ; Rotator Cuff* ; Shoulder ; Shoulder Pain

This study was to find out whether there were differences in the levels of depressions between positive and negative schizophrenics. This research was derived from the fact that negative schizophrenics show higher levels of depression than positive schizophrenics. This study also examined the levels of psychomotor dysfunction in positive and negative schizophrenics. For this study, there were 453 subjects. They consisted of 119 positive schizophrenics, 122 negative schizophrenics and 212 normal people. They were asked to complete Zung's Self-Rating Depression Scale(SDS) and to perform one subtest, Digit Symbol of KWIS(Korean Wechsler Intelligence SCALE). Subjects levels of depression were measured by the SDS. The level of psychomotor dysfunction was measured by Digit Symbol subtest of Korean Wechsler Intelligence Scale. ANOVA and Duncan's multiple comparison analysis were used to examine whether there were differences of depression and psychomotor dysfunction among the normal people, positive and negative schizophrenics. The results were as follows ; It was found that the depression level was higher in the negative schizophrenic patients than positive schizophrenic patients. Levels of depression were significantly higher in negative schizophrenics than positive schizophrenics. Psychomotor retardation symptom was the most effective variable that discriminates between the normals and the schizophrenics. And it would be concluded that the psychomotor dysfunction was more severe in negative schizophrenics than positive schizophrenics.
Depression* ; Humans ; Intelligence

Since the introduction of percutaneous balloon angioplasty by Gruentzig in 1979, percutaneous coronary intervention (PCI) has become the main treatment modality for the management of coronary heart disease. More than 1,000,000 PCI procedures are performed annually worldwide. With the advent of new therapeutic technologies, the indications for PCI have markedly expanded. Nowadays, improvements in balloon technology, popular use of coronary stent, and the proper administration of antiplatelet agents including GPIIbIIIa inhibitors have influenced the acute procedural outcomes. This technological and procedural advance in PCI has resulted in angiographic success rates of 96 to 99%, with Q-wave MI rates of 1 to 3%, emergency coronary bypass surgery rates of 0.2 to 3%, and unadjusted in-hospital mortality rates of 0.5~1.4%. However, despite the marked improvements in the acute outcome of PCI, long-term results including the restenosis rate are less impressive. The restenosis rate following balloon angioplasty reaches 30~40%, and is higher in certain clinical and angiographic subsets. The recent introduction of intracoronary stent and brachytherapy (intracoronary lesional ionizing radiation therapy) has a favorable impact on the restenosis precess including elastic recoil and intimal hyperplasia. Intracoronary stents decreased elastic recoil and remodeling and intracoronary radiation reduced intimal hyperplasia. Several randomized clinical trials to assess the efficacy of stents and intracoronary brachytherapy are ongoing with impressive results. In 2001, a breakthrough has been made in the prevention and the treatment of restenosis with the advent of a drug-eluting stent. Balloon-expandable stents coated with rapamycin or paclitaxol showed nearly 0% restenosis rate at 6-month follow-up. We might expect to solve restenosis completely in a very near future.
Angioplasty, Balloon ; Brachytherapy ; Coronary Disease ; Drug-Eluting Stents ; Emergencies ; Follow-Up Studies ; Hospital Mortality ; Hyperplasia ; Percutaneous Coronary Intervention* ; Platelet Aggregation Inhibitors ; Radiation, Ionizing ; Sirolimus ; Stents

The present study was designed to investigate if antithyroid antibodies (ATA) could affect the pregnancy outcome in euthyroid women undergoing in vitro fertilization and embryo transfer (IVF-ET). From October 1995 to September. 1996, 28 euthyroid women with ATA who underwent IVF-ET were studied. Fifty-one euthyroid women without ATA who underwent IVF-ET served as control. Thyroid peroxidase antibody (TPOA) and thyroglobulin antibody (TGA) were assayed using radio ligand assay kits as ATA. All patients included in study and control groups had only tubal factor in infertility. Long protocol of gonadotropin-releasing hormone agonist (GnRH-a) was used to. controlled ovarian hyperstimulation (COH) in all patients. There were no significant differences between study and control groups in patient characteristics such as age, infertility duration and hormonal profile. There were also no significant differences between two groups with respect to the clinical response to COH and IVF results such as number of retrieved oocytes, fertilization rate, number of embryos frozen and number of embryos transfered. There were no correlations between ATA (TPOA and TGA) titers and fertilization rate. The clinical pregnancy rate per cycle seemed to be lower in the study group than in the control group (26.3% vs 39.3%), but the difference was not statistically significant. The biochemical pregnancy rate per cycle and miscarriage rate were significantly higher in the study group at 18.4% (7/38) and 40.0% (4/10) compared with 5.6% (5/89) and 11.4% (4/35) in the control group. In the study group, both TPOA and TGA titers were significantly higher in the biochemical pregnancy group than in the clinical pregnancy group or non-pregnancy group. In 10 women with ATA who achieved pregnancy following IVF-ET, both TPOA and TGA titers were significantly higher in the miscarriage group than in the ongoing or delivery group. In conclusion, euthyroid women with ATA appear to represent a less favorable subset within other tubal factor patients when treated with IVF-ET.
Abortion, Spontaneous ; Antibodies* ; Embryo Transfer ; Embryonic Structures ; Female ; Fertilization ; Fertilization in Vitro ; Gonadotropin-Releasing Hormone ; Humans ; Infertility ; Iodide Peroxidase ; Oocytes ; Pregnancy ; Pregnancy Outcome ; Pregnancy Rate ; Thyroglobulin

In order to study the effect of lead exposure on the hematocrit and hemoglobin values in accordance with the level of lead exposure, twenty-four Sprague-Dawly rates were equally divided into four groups of six tars each. Lead acetate disolved in glucose was injected intrapertitoneally six times a week, for weeks with does of 0.05 mg/kg/day for group I, 0.5 mg/kg/day for group II, and 5 mg/kg/day for group III. Control group was injected glucose only. Blood samples for the checking of the hematocrit and hemoglobin values, were taking from tail vein of rats before lead injection and on the third, seventh, fourteenth, twenty-first, and twenty-eighth days after lead injection. And also, the concentration of lead and ALA in urine were checked for evaluating the lead absorption. The results were as follows ; 1. The alteration of the hematocrit and hemoglobin values of the group I was not significant as that of the control group. 2. In group II, the hematocrit values were significantly decreased from the fourteenth day after lead injection, and the hemoglobin values were decreased from the twenty- first day after lead injection when the concentration of lead in urine was elevated more than 260 microgram/liter. 3. In group III, the hematocrit value were decreased from the seventh day after lead injection, and the hemoglobin value were decreased even from third day after lead injection. And the hemoglobin values were more rapidly decreased than the hematocrit values. 4. In all group, the correlation coefficient between hematocrit and hemoglobin was highly significant. And the difference between the correlation coefficient of the group III and that of the others was highly significant.
Absorption ; Animals ; Glucose ; Hematocrit* ; Rats ; Tars ; Veins

No abstract available.
Diabetes Mellitus* ; Stents*

PURPOSE:Short stature relative to the familial height potential is a universial characteristics of patients with Turner syndrome. growth hormone(GH)therapy has been shown to improve adult height in Turner syndrome. this study was done to determine the effects of GH treatment. Objects and METHOD:178 patients were enrolled by investigators at multiple center. Diagnosis of Turner syndrome confirmed by karyotype analysis. Growth rate of 121 patients who were given Recombinant human GH(0.6-1.0IU/kg/Week) by subcutaneous injection for 1-3 years were analized. Final adult height was defined by the growth rate which was less than 1cm/year. RESULTS:Height velocity increased significantly during GH treatment, particularly in the first year. mean height velocity of our Turner patients was 6.3(+/-.39)cm/year during the first year(121 patients), 5.3(+/-.72)cm/year during second year(92 patients), 4.6(+/-.62)cm/year during third year(72 patients) after GH treatment. Mean height velocity of our Turner patients without GH treatment was 3.8(+/-.47)cm/year. the final adult height of our Turner patients with GH trearment was 143.0(+/-.6)cm. the final adult height without GH trearment was 139.6(+/-.9)cm. CONCLUSION: Our data demonstrate that GH treatment seems effective in accelerating growth velocity and in improving final height in Turner syndrome. the final height of our Turner patients is not to be considered the best result, as most of them was received GH therapy late age.
Adult ; Diagnosis ; Female* ; Growth Hormone* ; Humans ; Injections, Subcutaneous ; Karyotype ; Research Personnel ; Turner Syndrome*

The purpose of this article was to determine the discriminant function analysis of the Korean Wechsler Intelligence Scale (KWIS) for 110 normal controls and 98 schizophrenics. Of special interest was to verify the clinical discriminant power of two subtests of the KWIS (Vocabulary and Digit Symbols) and Zung's Self-rating Anxiety Scale (SAS). Four major hypotheses were postulated. The normal control group would show higher scores then the schizophrenics; mean scores on both Vocabulary and Digit Symbol. The mean difference in Digit Symbol between the two groups would be greater than that in the Vocabulary. There would be no significant relation among Digit Symbol, Vocabulary, and Anxiety. The most powerful discriminant power would be expected from subtest of Digit Symbol. The mean discriminant scores were 1.34425 for the control subjects, 1.34425 for the schizophrenics. The correctly discriminated percentage was 89.1% for the control subjects, 90.8% for the schizophrenics. From the findings it was concluded that both Digit Symbol and Vocabulary scales had strong diagnostic value but the former was more powerful than the latter. However, the Anxiety scales had less diagnostic value.
Anxiety ; Humans ; Intelligence ; Vocabulary ; Weights and Measures