1.Analysis of the risk factors between anterior and posterior intracranial artery stenosis in acute stroke patients
Yanqiang CHEN ; Xueping ZHANG ; Hongzhong BAI ; Liheng ZHENG ; Qing ZHANG
Clinical Medicine of China 2013;29(9):897-900
Objective To investigate the association between vascular risk factors and the location of intracranial artery stenosis (anterior versus posterior).Methods Magnetic resonance angiography(MRA) were examined in 374 acute stroke patients.It was divided into two groups (anterior and posterior intracranial artery stenosis group).Analyzed possible risk factors.Results Univariate analysis showed there were differences between anterior and posterior intracranial artery stenosis in systolic blood pressure,history of smoking,drinking and stroke status,and national institutes of health stroke scale (NIHSS) score at discharge,short-term prognosis,serum creatinine,triglyceride,low density lipoprotein cholesterol (LDL-C) (P < 0.05).In multivariate logistic regression analysis,high blood sugar (OR =1.135,95% CI:1.003-1.284),history of stroke(OR =1.133,95% CI:1.007-1.276),good short-term prognosis (OR =5.987,95% CI:1.441-24.873) were preferentially related to anterior intracranial artery stenosis,whereas history of smoking (OR =0.003,95 % CI:0.000-0.376),high serum creatinine values (OR =0.509,95 % CI:0.328-0.790),high triglyceride values (OR =0.054,95% CI:0.004-0.645) and high LDL-C values (OR =0.096,95% CI:0.015-0.608) were preferentially related to posterior intracranial artery stenosis.Conclusion Vascular risk factors appeared to exert different effects of risk for anterior and posterior intracranial artery stenosis.
2. Application value of interferon gamma release assay combined with tuberculin skin test in diagnosis of intraocular tuberculosis and latent tuberculosis infection
Yankun ZHANG ; Hongzhong BAI ; Yan GUAN ; Yujing LI ; Xiaoying AN ; Chao HAN
Chinese Journal of Postgraduates of Medicine 2019;42(9):791-795
Objective:
To explore the application value of interferon gamma release assay (IGRA) combined with tuberculin skin test (TST) in diagnosis of intraocular tuberculosis and latent tuberculosis infection.
Methods:
One hundred and ten patients with pulmonary tuberculosis (observation group) and 80 healthy persons (control group) in Hebei Chest Hospital from January 2016 to December 2018 were selected. Among the 110 patients with pulmonary tuberculosis, intraocular tuberculosis was in 35 cases, and latent tuberculosis infection was in 75 cases. All the patients were examined by ocular secretions IGRA and TST.
Results:
The positive rates of IGRA and TST in observation group were significantly higher than those in control group: 88.18% (97/110) vs. 11.25% (9/80) and 83.64% (92/110) vs. 41.25% (33/80), and there were statistical differences (