1.Prediction of plasma myeloperoxidase on cardiovascular event of patients with stable angina pectoris
Clinical Medicine of China 2014;30(2):118-121
Objective To explore the independent prognostic value of plasma myeloperoxidase (MPO) in cardiovascular event of patient with stable angina pectoris.Methods Two hundred and forty-seven patients with stable angina pectoris (defined as 50% stenosis in any coronary vessel) were selected as our subjects and they all were followed up for 2 years.Plasma MPO and hsCRP concentrations were measured.The major adverse cardiovascular events (MACEs),including death,myocardial infarction and stroke,occurred in patients were recorded.Results All patients were divided into high MPO group (84 cases and plasma MPO concentrations over 320 mg/L) and low MPO group (163 cases,plasma MPO concentrations less than 320 mg/L).Compared with patients in low MPO group,the risk of occurring MACEs in high MPO group was higher(HR =1.67,95% CI =1.32-2.57,P < 0.05).There was positive correlation between plasma MPO and hsCRP concentrations (r =0.132,P < 0.05).Conclusion MPO level may serve as a better prediction index for adverse cardiovascular events of patients with Stable angina pectorisindependently.MPO has relationship with hsCRP concentrations.
2.Changes of serum nitric oxide and nitric oxide synthase in acute cerebral hemorrhage with multiple organ dysfunction syndrome caused by systemic inflammatory response syndrome
Journal of Clinical Neurology 1988;0(02):-
Objective To explore the possible mechanism of acute cerebral hemorrhage with systemic inflammatory response syndrome (SIRS) which caused multiple organ dysfunction syndrome (MODS), and to investigate the significance of serum nitric oxide (NO) and nitric oxide synthase (NOS) in the development of acute cerebral hemorrhage from SIRS to MODS.Methods The incidence rate of acute cerebral hemorrhage leading to SIRS and MODS was investigated. Serum NO and NOS levels in 73 patients with acute cerebral hemorrhage were detected dynamically by nitratase and chromometry methods. 20 normal healthy people were adopted as control group.Results The incidence rate of cerebral hemorrhage accompanied with SIRS was 47.95%(35/73),74.29%(26/35) of which leaded to MODS. 73 patients serum NO and NOS levels were elevated obviously, and the differences were significant compared with control group (all P
3.Comparative Study of Thymosin α1 Combining Anti-coagulation Medication and Simple Anti-coagulation Medication for Treating the Patients With Deep Venous Thrombosis Formation
Chinese Circulation Journal 2015;(6):556-558
Objective: To compare the therapeutic effect of thymosin α1 combining anti-coagulation medication and simple anti-coagulation mediation in treating the patients with deep venous thrombosis (DVT) formation. Methods: A total of 92 patients with lower extremity vascular ultrasound conifrmed diagnosis of DVT were studied. The patients were randomly divided into 2 groups for treatment: Combination group, the patients received thymosin α1 combining anti-coagulation medication,n=45 and Simple group, the patients received only anti-coagulation medication,n=47. The changes of their deep venous thrombosis condition after treatment were compared between 2 groups. Results: By 4 weeks treatment, the proportion of completely dissolved thrombus in Combination group and in Simple group were 67 branches (49.26%) and 54 branches (37.24%); the thrombus progression and recurrence condition were 6 branches (4.41%) and 16 branches (11.03%), allP<0.05. Conclusion: Thymosin α1 combining anti-coagulation medication has the better effect than simple anti-coagulation medication for treating DVT patients.
4.Treatment of neurofibromatosis scoliosis by vascularized grafted rib
Chinese Journal of Microsurgery 2000;0(04):-
Objective To evaluate the clinical effect of neuromatosis scoliosis treated by vascularized grafted rib Method The clinical date of 16 cases of neuromatosis scoliosis treated by surgical operation were analysed retrospectively Result Sixteen patients with scolisis caused by neurofibromatosis were treated by this technique The clinical result was satisfactory and solid fusion was observed in all patients within 6 months after operation Conclusion This operation is an effective method for the treatment of neuromatosis scoliosis
5.Cases of herb pairs for treatment of breast hyperplasia
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
TCM has shown prominent effect on treating breast hyperplasia,especially pair herbs has done.This article enumerates several common used herb pairs for treatment of breast hyperplasia from the aspects of soothing the liver and regulating qi,regulating blood and removing blood stasis,resolving phlegm,warming yang and tonification.And analyze the compatible characteristics of common used herb pairs in clinic.
6.Current Situation Research on Distribution Mode of Centralized Purchasing Drugs in Henan Province
Zeyu ZHANG ; Hongzhi AN ; Linzhi LI
China Pharmacist 2017;20(1):174-176
Objective:To analyze the structure of supply and demand, the distribution status of essential drugs and low-cost drugs and the influencing factors in the distribution, and provide strategies and suggestions. Methods:The literature research, Delphi method, sampling survey and the other methods were used to analyze the effects of distribution pattern on the drug distribution in Henan, and then optimization measures were studied systematically. Results:The distribution mode of centralized purchasing drugs was the major influen-cing factor in the drug distribution rate and enthusiasm. Conclusion:The distribution of centralized purchasing drugs should stick to the principles of essential drugs priority and reasonable use in order to enhance the distribution enthusiasm of manufacturers. The distribution should base on the two-way choice distribution mode and combine with the mode of centralized distribution and independent choice, mean-while, the information technology should be improved to optimize dynamic management of distribution and promote the effectiveness of drug delivery.
7.Cause and clinical analysis of lumbar reoperation
Bing LI ; Long LI ; Hongzhi SUN
Orthopedic Journal of China 2006;0(03):-
[Objective] To investigate the causes,indications,operative methods and clinical results of lumbar reoperation.[Methods]Twenty-eight failure lumbar procedure cases were received reoperation from May 2003 to May 2005.There were 16 males and 12 females.These cases were from 31 to 70 years old(mean 47).It took a mean 1 year and 8 month(from 1 month to 8 year)from last operation to this registry.The causes of reoperation included rehemiated disc nucleus pulpous,degeneration of adjacent segment and instability and insufficiency of canal decompression.Some cases of discogenic back pain were operated by mistaken procedure.Some cases involved severe complications including infection in disc space or vertebral itself,pedicle screws misposition,aneurysm formation and CSF leakage.The operative methods included rediscectomy,lumbar canal decompression,and lumbar reconstruction by implant and fusion.[Results]The operative time and blood lose were from 50 to 350 minutes(mean 213)and from 100 to 3 000 ml(mean 760 ml)respectively.One patient died because of severe abdominal cavity infection.The other cases were recovered and clinical complaint became less.The VAS and Oswestry Disability Index decreased from(7.9?1.6)and(52.4?7.2)to(2.8?1.0)and(8.3?3.6)respectively(the decrease rate:64.3% and 66.5%)after 24 to 48 months follow-up(mean 32.8 months).[Conclusion]The causes of failure lumbar procedure must be analyzed as soon as possible.The risks and benefits of reoperation must be balanced although it may make patients get more chance to recovery.It is very difficult for these procedures and the risks are also high.The dura sac rupture is the most common complication.It is the most important to deal with the adhesion and bleeding control in canal.The use of the magnification and lighting equipment can reduce the complications.
8.Study on the Reaction and Significance of Astrocytes in Surrounding Areas after Cerebral Hemorrhage of Human
Guangwei LI ; Hongzhi MAO ; Bo LI
Journal of Medical Research 2006;0(01):-
Objective To observe expression of GFAP,research the reaction and significance of astrocytes in the surrounding areas after cerebral hemorrhage of human.Methods He and immunohistochemistry are used to observe changes of glial fibrillary acidic protein(GFAP)and SPSS11.5 was used to analyse the results.Results The expressions of GFAP started to increase in 2h(P
9.Application of nursing aid process on traffic accident aid to orthopedic patients
Cong ZHAO ; Hongzhi WANG ; Yonghui LI
Modern Clinical Nursing 2015;14(9):48-50
Objective To investigate the effect of nursing rescue process on traffic accident aid to orthopedic patients . Methods Sixty patients with bone injuries from traffic accidents during April to December 2013 were set as control group , in which the traditional aid process was used for rescue, and another 60 patients during January to June 2014 as experiment group, in which the nursing aid process was applied. The two groups were compared in terms of rescue time and effectiveness. Result The rescue time in the experiment group was significantly shorter and the first aid effectiveness was also better than those in control group (P<0.01). Conclusion By nursing aid process, the personnel can be optimized to avoid chaos during the rescue and meanwhile the time for rescue is shortened, which can contribute the increased success rate.
10.Transformation of government function of health management under the perspective of new public service theory
Jing LIU ; Zhi LI ; Hongzhi WANG
Chinese Journal of Hospital Administration 2008;24(7):433-436,440
The paper analyzes the orientation of health management function of government under the perspective of new public service theory, tries to reveal the unimplementation, dislocation, offside and absence of government function at four aspects including health service system, health organization operating mechanism, health management system and health service supervision system, and puts forward six approaches for transformation of government function of health management.