Objective:To explore the effect of setting up a special elderly bowel preparation nursing group to implement optimized holistic nursing on the quality of peri-enteroscopy in elderly patients.Methods:Using the convenient sampling method, a total of 128 elderly inpatients who were scheduled to undergo ordinary or painless enteroscopy in Beijing Tongren Hospital from October 2015 to July 2018 were selected. They were randomly divided into the control group ( n=57) and the observation group ( n=71) . The control group was given routine nursing, while the observation group was given optimized holistic nursing mode. The safety of intestinal preparation, intestinal cleanliness and satisfaction of patients were compared between the two groups. Results:During intestinal preparation, a total of 56 patients in the observation group and 36 patients in the control group had excellent intestinal comfort. There was a statistically significant difference in comfort between the two groups ( Z=2.31, P< 0.05) . There were 64 cases in the observation group and 36 cases in the control group with grade 1-2 intestinal cleanliness. The difference in intestinal cleanliness between the two groups was statistically significant ( Z=4.05, P< 0.01) . Conclusions:The implementation of optimized nursing mode by the elderly bowel preparation nursing group can help improve the quality of bowel preparation of hospitalized elderly inpatients.