Objective To investigate the diagnostic difference between preoperative diagnostic curettage and postoperative pathological diagnosis in endometrial carcinoma,and provide guidance for the accuracy in preoperative diagnosis of endometrial carcinoma.Methods The data of 124 endometrial carcinoma patients were retrospectively analyzed,including clinical stage,pathological stage,pathological type,histologic grade,etc.Results In 124 endometrial carcinoma patients,102 cases of endometrial carcinoma were found by preoperative diagnostic curettage,the diagnostic accordance rate was 82.3％ (102/124),misdiagnosis was in 22 cases,the misdiagnosis rate was 17.7％(22/124).The total accordance rate of preoperative clinical stage and postoperative pathological stage was 81.4％ (83/102) in 102 patients who had the same preoperative and postoperative diagnosis,and the accordance rate of Ⅰ stage was 86.1％ (62/72),the accordance rate of Ⅱ stage was 72.0％(18/25),the accordance rate of Ⅲ stage was 3/5.The total accordance rate of preoperative diagnostic curettage histologic grade and postoperative pathological histologic grade was 65.7％(67/102),and the accordance rate of G1 grade was 55.6％ (25/45),the accordance rate of G2 grade was 69.2％ (27/39),the accordance rate of G3 grade was 15/18.Conclusions The pathological type,pathological stage and histologic grade of preoperative diagnostic curettage and postoperative pathological diagnosis in endometrial carcinoma are not always consistent.A variety of diagnostic methods should be considered together in order to reduce the diagnosis difference preoperative and postoperative,and improve the accordance rate of preoperative diagnosis.

To study the visual magnocellular deficit in alphabetic and Chinese developmental dyslex?ia from behavioral,neural mechanism and intervention studies,critical words in Chinese and English (de?velopmental dyslexia and magnocellular pathway or dorsal stream or contrast sensitivity or coherent mo?tion ) were searched in Chinese and English databases(CNKI,PubMed,ScienceDirect,etc.) from Septem?ber to December,2015. Forty?three relevant articles which aimed to investigate the visual magnocellular defi?cit in developmental dyslexia were selected among 75 articles according to the searching result and the objec?tive of the present study. The results showed that alphabetic studies consistently consistently manifested the magnocellular deficit in developmental dyslexia from the aspects of behavioral performance,neural activities and intervention effects. However,whether the deficit was the cause or the consequence of dyslexia remains controversial. In Chinese,most of studies on magnocellular deficit of developmental dyslexia were behavioral. There were few studies from aspects of neural mechanism and intervention. Alphabetic and Chinese studies consistently manifested magnocellular deficit in developmental dyslexia,suggesting the consistency across lan?guages. However,more comprehensive studies are required to further explore the causal relationship between magnocellular deficit and developmental dyslexia.

Objective:To investigate the rationality of prophylactic antibiotics application during perioperative period in the pa-tients with type Ⅱ incision operation in gynecology and obstetrics in our hospital after the intervention. Methods:Totally 274 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2012 to March 2013 were collect-ed as the control group, another 321 medical records of obstetrics and gynecology patients with typeⅡincision operation in our hospital from April 2013 to March 2014 were collected as the intervention group. The rationality of prophylactic antibiotics application before and after the intervention was compared. Results:Compared with those in the control group, the average administration time, the hos-pitalization time and the cost of antimicrobial agents were significantly decreased in the intervention group (P<0. 05). The incidence of adverse drug reactions and operation incision infection between the two groups was not significant difference (P>0. 05). Compared with those in the control group, the incidence of irrational choice of antibacterial drugs, the combined use without indication, irrational medication time,over-time use, inappropriate use and improper choice of solvents in the intervention group was significantly reduced ( P<0. 05). Conclusion:After the intervention, the rationality of prophylactic antibiotics application during perioperative period in the patients with type Ⅱ incision operation in gynecology and obstetrics in our hospital is improved significantly.

Objective To investigate the effect of play therapy on childhood autism.Methods A child with autism treated with play therapy was reported.Results and Conclusion The play therapy is helpful to improve the social skill of the children with autism.

BACKGROUND: Hyperlipemia is one of the important risk factors of coronary atherosclerotic cardiopathy. Great attention has been paid on how to explain the correlation between blood lipid and coronary heart disease and the correlation of characteristics and level of blood lipid with coronary heart disease.OBJECTIVE: To probe into the correlation among the characteristics, the level of blood lipid and coronary heart disease in senile people.DESIGN: Case-control observation and stratified analysis.SETTING: Second Cadre Ward of General Hospital of Shenyang Military Area Command of Chinese PLA.PARTICIPANTS: Totally 105 inpatients were selected in coronary heart disease group, diagnosed as coronary heart disease, tallied with WHO Diagnostic Standard on Coronary Heart Diseases, in Second Cadre Ward of General Hospital of Shenyang Military Area Command of Chinese PLA from January 2001 to January 2002. Totally 99 inpatients, by checked, without coronary heart disease and cerebral vascular disorder were selected in the control in the same period.METHODS: 2 mL venous blood was collected in fasting in the morning and the serum was collected after centrifuged at 3 000 r/minute, for 5 minutes. Auto-biochemical analyzer and enzyme kit were used to determine cholesterol, triglycerin, high density lipoprotein cholesterol and low density lipoprotein cholesterol. Compared with the data in the control, the ranges of cholesterol, triglycerin and low density lipoprotein were calculated successively and divided by 10; at the class intervals of 0.53, 0. 39 and 0.29 mmonl/L, the frequency table was worked out. According to the frequency table, P25 (the 25th percentile), P50 (the 50th percentile), P75 (the 75th percentile) and P90 (the 90th percentile) of cholesterol, triglycerin and low density lipoprotein cholesterol were calculated successively. The stratified groups were divided based on P ＜ 25, P25 to PS0, PS0 to P75, P75 to P90 and ＞ P90, by which, the cases belonging to 5 groups were determined in coronary heart disease group and the control respectively. The exposure factor was determined by ＞ P90, compared with other 4 groups, Menta-Haensecel method was used to calculate x2. If the exposure factor was related with coronary heart disease, the relevant coefficient and 95% confidence interval should be calculated. In accordance with the standards (Proposal on Prevention of Abnormal Blood Lipid and Targets of Abnormal Blood lipid on 2-grade Prevention of Coronary Heart Disease), the cases beyond the targets and morbidity were determined in two groups.MAIN OUTCOME MEASURES: Determination of blood lipid, abnormal cases and morbidity in two groups; cases beyond targets of blood lipid and morbidity; stratified comparisons of percentiles in two groups.RESULTS: According to intention measurement, 204 cases entered result and the control, there was no significant difference in cholesterol, triglycerin cases presented hypercholesterolemia, 34.3% cases hypertriglycerlipidemia and 11. 4% cases low density lipoprotein-hypercholesterolemia. It was indicated that the blood lipid was in the normal range among 64. 8% to 88.6% comparison between the cases with cholesterol ≥5.47 mmonl/L and the cases with cholesterol varied from 3.85 to 4.63 mmol/L, the morbidity of coronary heart disease in the former was 2.98 times as high as the latter (x2 = 6.29, 95% confidence interval was 1.27 -6.98) . In the comparison between the cases with cholesterol ≥ 5.47 mmol/L and the cases with cholesterol varied from 4.64 to 5.05 mmol/L, the correlation with coronary Lipid for 2nd Prevention of Coronary Heart Disease, among the patients with coronary heart disease, cholesterol ≥ 4.68 mmonl/L in 54. 2% cases,triglycerin ≥ 1.70 mmol/L in 34. 3% cases and low density lipoprotein ≥ 2.6 mmol/L in 52. 3% cases.CONCLUSION: For senile patients with coronary heart disease, the satisfactory level of cholesterol is 3.85- 4.63 mmol/L. For those with cholesterol ≥ 5.47 mmol/L, compared with those varied from 3.85 to 4.63 mmol/L, the morbidity of coronary heart disease in the former is possibly 2.98 times as same as the latter(x2 = 6.29, 95% confidence interval was 1.27 - 6.98).

Specific antibodies purified from sera of rabbit infected with Toxoplasma gondii were used to immun-oscreen the 12-mer and 7-mer phage random peptide libraries. By 3 rounds of screening, 70 clones were picked out ra-ndomly to test the specificity and 43 were found positive by ELISA. 23 of the 43 positive clones showing strong reaction in ELISA were picked out for sequencing. Clone A7 was selected as mimic antigen in ELISA test after analysis of the 23 short peptide sequences. 23 out of 47 sera from rabbits infected with Toxoplasma gondii were ELISA positive by A7 mimic antigen with a positive rate of 68.1%, and 10 of 155 sera from healthy persons showed false positive with a sp-ecificity of 93.5%. The primary result suggests that mimic antigen may have a potential use in diagnose of toxoplasmosis.

Objective To investigate the psychological condition of the rural residents with HIV/AIDS.Methods Totally 192 subjects with HIV/AIDS residing in countryside of Henan Province(China)were investigated with questionaire and Symptom Check list 90(SCL-90).Results SCL-90 total score,the number of positive items and the score of each factor for the 192 subjects with HIV/AIDS were higher than those of Chinese normal(P

Objective To investigate the genetic faction influence on asthmatic patients in Chongqing, China. Methods Case-control study was employed for genetic epidemiological survey. Results The heritability of asthma in Chongqing was (80.56?5.68)% in first-degree relatives of asthma probands. The segregation ratio was 0.18. The relative risk of first-degree relatives and siblings of asthma probands were 7.38 and 4.47, respectively. Conclusion The inheritance pattern of asthma in Chongqing coincided with polygenic inheritance pattern. Genetic factor is a major risk factor of asthma. The relative risk in siblings is high. We can localize the susceptible gene of asthma with positional cloning.

[ABSTRACT]OBJECTIVETo explore the clinical characteristics of benign paroxysmal positionalvertigo(BPPV) after sudden hearing loss and to observe the curative effect. METHODS36 patients with BPPV after sudden hearing loss were observed.And their therapeutic findings were compared with that of the 50 patients with primary BPPV and 40 patients of sudden hearing loss without vertigo. RESULTSBPPV after sudden hearing loss occurred in the hearing loss ears, of which 27 cases were posterior semicircular canal lithiasis and 3 cases were horizontal semicircular canal lithiasis. The 36 patients with BPPV after sudden hearing loss and 40 patients with primary BPPV were cured after several times of reposition maneuver treatment.The efficiency of 40 patients of sudden hearing loss without vertigo was higher than that of 36 patients with BPPV after sudden hearing loss.CONCLUSIONBPPV after the sudden hearing loss mainly occurs in the posterior semicircular canal. The therapeutic efficacy of canalith repositioning maneuver for the secondary BPPV was similar to that of the primary BPPV.The therapeutic efficacy of sudden hearing loss without vertigo was superior to sudden hearing loss with BPPV.

Objective To find out the condition of the quality of life and social support in patients with chronic kidney disease (CKD)and analyze the their correlation.Methods Adopt stratified random sampling method take samples 200 CKD patients who were treated at chronic Kidney disease of internal of general hospital form March to June 2014 in Luzhou city.Then completed the instruments of the Social Support Rating Scale (SSRS)and the quality of life scale (KDQOL-SFTM ).Results Objective support score of social support for patients with CKD was higher than the national average(P <0.05);Total score of social support and subjective support,social support utilization degree score were lower than the national average(P <0.05).The score was less than 60 in KDQOL-SFTM from low to high followed by kidney disease burden(BKD),work status(WS),sexual function(SexF),the lim-ited strength caused by working and living (RP),general health(GH),were basically identical with other research results.The so-cial support and quality of life had a positive correlation.Conclusion The social support and quality of life in the patients with CKD are lower than the normal people,and there is a positive correlation between them.One of the main task is to improve social support network for patients with chronic kidney disease(CKD).