ObjectiveTo find out whether there is any difference in the monitoring results of mosq-ovitraps placed in different orientations in multi-storey residential areas, so as to provide a scientific basis for routine and emergency monitoring of Aedes albopictus with mosq-ovitraps in residential areas. MethodsFrom July 6th to October 26th 2023, one mosquito ovitrap was set up in each of the 4 orientations of east, south, west and north around the buildings in a multi-storey residential area in Jinhui Town, Fengxian District, Shanghai. Data was collected and recorded 72 hours after placement. The chi-square test was used to compare the mosquito ovitrap indices (MOIs) of two independent samples, and the Kruskal⁃Wallis H test was used to compare the MOIs of multiple independent samples. ResultsAfter 16 weeks of surveillance, 997 mosquito ovitraps were recovered, of which 211 were positive, with the mosquito ovitrap index (MOI) of 21.16% and the Aedes albopictus density index of 1.03 mosquitoes·ovitrap^-1. The MOIs were higher in September (24.22%) and October (23.96%), and the MOIs in the west, south and north within the two months were all above 20.00%. From July to October, the MOIs in the east, west, south and north were 20.70%, 22.20%, 25.50% and 16.20%, respectively, and the difference in MOIs among the 4 orientations was not statistically significant (χ²=6.647, P=0.084). Stratified analysis by month showed that in August, the south side of the multi-storey residential areas had the highest MOI (31.30%), the north side had the lowest MOI (1.30%), and there was a statistically significant difference in MOI in the east, west, south and north (χ²=25.986, P<0.001). In October, the MOI in the west was the highest (33.30%) and the MOI in the east was the lowest (6.30%), the difference in MOIs of the 4 orientations was statistically significant (χ²=12.007, P=0.007). The MOIs in the south side of the building in the outskirts of the residential area from the 1st week in July to the 4th week in October was lower (19.20%) than that in the south side of the inner building (31.70%), and the difference in MOI was statistically significant (χ²=5.118, P=0.024). ConclusionThe study of MOI in different orientations in a multi-storey residential area is a preliminary exploration based on field work, and the results show that there is a difference in MOIs in different orientations during the peak breeding period of mosquitoes. Further indicators such as temperature, humidity and wind speed in different orientations can be collected to explore the influencing factors of MOIs.

Objective:To explore the clinical effect of the whole-process management scheme of daytime minimally invasive liver resection surgery based on the enhanced recovery after surgery (ERAS) concept.Methods:This is a retrospective case series study. The data of 55 patients who underwent minimally invasive daytime liver resection surgery under the ERAS concept at the Department of General Surgery,Sir Run Run Shaw Hospital, Zhejiang University School of Medicine from January 2023 to August 2024. There were 22 males and 33 females;aged (48.2±15.1) years (range: 16 to 77 years). All patients were classified as Grade 2 according to the American Society of Anesthesiologists physical status classification. Among them, 7 cases were complicated with liver cirrhosis and 10 cases had fatty liver. A multidisciplinary team was formed, consisting of surgeons, anesthesiologists, rehabilitation physicians, psychologists, pharmacists, acute pain management team, operating room nurses, day surgery ward nurses, and ERAS specialized nurses. After strict evaluation by surgeons and anesthesiologists, patients suitable for daytime liver resection surgery were implemented with the ERAS whole-process management plan for liver resection on the basis of routine nursing care.Results:Among the 55 patients, 50 were discharged smoothly within 48 hours, while 5 were transferred to specialized departments for further treatment due to not meeting the discharge criteria, with a smooth daytime discharge rate of 90.9%. Among the 50 patients, 30 underwent laparoscopic surgery and 20 underwent robotic-assisted surgery. The surgery time was (91.6±28.2)minutes(range:45 to 165 minutes), with the intraoperative blood loss of only (30.5±25.5)ml(range:5 to 100 ml). Pathological examination results showed that among the 50 patients, 13 cases had hepatocellular carcinoma, 21 cases had hepatic hemangioma, 4 cases had hepatic cyst, 8 cases had focal nodular hyperplasia, 1 case had low-grade dysplastic nodule, 1 case had hepatolithiasis, 1 case had lymphoma, and 1 case had vascular, fibrous and lymphoid tissue proliferation. There were 44.0% patients who were able to get out of bed on the day of surgery. The hospital stay was (1.8±0.4)days(range:1 to 2 days), and the hospitalization cost was (34 499±20 330)yuan(range:11 724 to 73 488 yuan). No complications requiring special treatment outside the conventional pathway were observed during the hospital stay and follow-up period. At the 2-week outpatient follow-up, no significant abnormalities were found in all patients, and the wound healing was good.Conclusions:The daytime liver resection surgery based on the ERAS whole-process management plan has shown good feasibility in clinical practice. It helps to simplify medical process, shorten hospital stay, and reduce medical costs.

Immune checkpoint inhibitors(ICI)are monoclonal antibodies that could restore and improve the ability of T lymphocytes to specifically recognize and kill tumor cells by inhibiting immune checkpoint activity,this therapeutic strategy is a breakthrough in the treatment of malignant solid tumors in recent years.ICI-associated myocarditis(ICI-M)is one of the immune-related adverse events with rapid onset,severe symptoms and rapid progression.However,the clinical understanding of ICI-M is insufficient at present.This article reviews current research progress on epidemiology,pathogenic mechanism,diagnosis and treatment of ICI-M.

Objective:To summarize the risk prediction models for postoperative hypoxemia and provide a reference for clinical nursing practice and future research on hypoxemia risk prediction models for postoperative patients.Methods:A systematic literature search was conducted in CNKI, CBM, Wanfang, PubMed, Web of Science Core Collection, Cochrane Library, Embase, and CINAHL databases, covering publications up to January 31, 2024. Two researchers independently screened the literature, extracted data, performed integrative analysis, and evaluated the risk of bias in the included studies.Results:Seventeen studies were included, involving 17 different prediction models. The study populations were primarily adult patients, with hypoxemia incidence rates ranging from 2.40% to 49.30%. Modeling methods included Logistic regression and decision tree algorithms. The presentation formats of the models included risk scoring formulas, nomograms, decision tree diagrams, and web calculators. The five most frequently identified predictive factors were body mass index, age, comorbidities, duration of intraoperative cardiopulmonary bypass, and preoperative white blood cell count. Sixteen models reported the area under the receiver operating characteristic curve ranging from 0.667 to 0.916. All 17 studies exhibited varying degrees of bias risk.Conclusions:Existing risk prediction models for postoperative hypoxemia demonstrate good performance; however, the bias risk level of all studies was high. Future research should standardize the model development process according to bias risk assessment checklists to establish models with low bias risk and strong clinical applicability.

This article provides an overview of ecological momentary assessment based on mobile information devices. It reviews the design frameworks, domestic and international research progress, and the challenges associated with its application. The study aims to offer insights and reference methods for developing electronic ecological momentary assessment platforms in China.

Objective:To summarize the risk prediction models for postoperative hypoxemia and provide a reference for clinical nursing practice and future research on hypoxemia risk prediction models for postoperative patients.Methods:A systematic literature search was conducted in CNKI, CBM, Wanfang, PubMed, Web of Science Core Collection, Cochrane Library, Embase, and CINAHL databases, covering publications up to January 31, 2024. Two researchers independently screened the literature, extracted data, performed integrative analysis, and evaluated the risk of bias in the included studies.Results:Seventeen studies were included, involving 17 different prediction models. The study populations were primarily adult patients, with hypoxemia incidence rates ranging from 2.40% to 49.30%. Modeling methods included Logistic regression and decision tree algorithms. The presentation formats of the models included risk scoring formulas, nomograms, decision tree diagrams, and web calculators. The five most frequently identified predictive factors were body mass index, age, comorbidities, duration of intraoperative cardiopulmonary bypass, and preoperative white blood cell count. Sixteen models reported the area under the receiver operating characteristic curve ranging from 0.667 to 0.916. All 17 studies exhibited varying degrees of bias risk.Conclusions:Existing risk prediction models for postoperative hypoxemia demonstrate good performance; however, the bias risk level of all studies was high. Future research should standardize the model development process according to bias risk assessment checklists to establish models with low bias risk and strong clinical applicability.

This article provides an overview of ecological momentary assessment based on mobile information devices. It reviews the design frameworks, domestic and international research progress, and the challenges associated with its application. The study aims to offer insights and reference methods for developing electronic ecological momentary assessment platforms in China.

Immune checkpoint inhibitors(ICI)are monoclonal antibodies that could restore and improve the ability of T lymphocytes to specifically recognize and kill tumor cells by inhibiting immune checkpoint activity,this therapeutic strategy is a breakthrough in the treatment of malignant solid tumors in recent years.ICI-associated myocarditis(ICI-M)is one of the immune-related adverse events with rapid onset,severe symptoms and rapid progression.However,the clinical understanding of ICI-M is insufficient at present.This article reviews current research progress on epidemiology,pathogenic mechanism,diagnosis and treatment of ICI-M.

Objective:To explore the clinical effect of the whole-process management scheme of daytime minimally invasive liver resection surgery based on the enhanced recovery after surgery (ERAS) concept.Methods:This is a retrospective case series study. The data of 55 patients who underwent minimally invasive daytime liver resection surgery under the ERAS concept at the Department of General Surgery,Sir Run Run Shaw Hospital, Zhejiang University School of Medicine from January 2023 to August 2024. There were 22 males and 33 females;aged (48.2±15.1) years (range: 16 to 77 years). All patients were classified as Grade 2 according to the American Society of Anesthesiologists physical status classification. Among them, 7 cases were complicated with liver cirrhosis and 10 cases had fatty liver. A multidisciplinary team was formed, consisting of surgeons, anesthesiologists, rehabilitation physicians, psychologists, pharmacists, acute pain management team, operating room nurses, day surgery ward nurses, and ERAS specialized nurses. After strict evaluation by surgeons and anesthesiologists, patients suitable for daytime liver resection surgery were implemented with the ERAS whole-process management plan for liver resection on the basis of routine nursing care.Results:Among the 55 patients, 50 were discharged smoothly within 48 hours, while 5 were transferred to specialized departments for further treatment due to not meeting the discharge criteria, with a smooth daytime discharge rate of 90.9%. Among the 50 patients, 30 underwent laparoscopic surgery and 20 underwent robotic-assisted surgery. The surgery time was (91.6±28.2)minutes(range:45 to 165 minutes), with the intraoperative blood loss of only (30.5±25.5)ml(range:5 to 100 ml). Pathological examination results showed that among the 50 patients, 13 cases had hepatocellular carcinoma, 21 cases had hepatic hemangioma, 4 cases had hepatic cyst, 8 cases had focal nodular hyperplasia, 1 case had low-grade dysplastic nodule, 1 case had hepatolithiasis, 1 case had lymphoma, and 1 case had vascular, fibrous and lymphoid tissue proliferation. There were 44.0% patients who were able to get out of bed on the day of surgery. The hospital stay was (1.8±0.4)days(range:1 to 2 days), and the hospitalization cost was (34 499±20 330)yuan(range:11 724 to 73 488 yuan). No complications requiring special treatment outside the conventional pathway were observed during the hospital stay and follow-up period. At the 2-week outpatient follow-up, no significant abnormalities were found in all patients, and the wound healing was good.Conclusions:The daytime liver resection surgery based on the ERAS whole-process management plan has shown good feasibility in clinical practice. It helps to simplify medical process, shorten hospital stay, and reduce medical costs.

Objective:The aim of this study was to investigate the clinical characteristics and analyze the risk factors of patients with acute dichlorvos poisoning combined with shock.Methods:The clinical data of patients with acute dichlorvos poisoning admitted to the Peking University Third Hospital and the Fifth Medical Center of the PLA General Hospital between January 2019 and September 2020 were retrospectively analyzed, and demographic data, poisoning, clinical manifestations, laboratory tests, therapeutic measures and clinical outcomes were collected to establish a clinical database. The patients were divided into two groups: the shock group and the non-shock group, and the clinical data were compared between the two groups to analyze the clinical characteristics and prognosis of shock in acute dichlorvos poisoning, and the risk factors of shock in acute dichlorvos poisoning were analyzed by logistic regression.Results:A total of 134 patients who met the criteria for acute dichlorvos poisoning were included in this study; the incidence of shock within 24 hours of admission was 39.6% (53/134), and 11 patients (8.21%) died in hospital; the in-hospital morbidity and mortality rate of patients in the shock group was higher than that in the non-shock group (20.8% vs. 0.0%, P<0.001). Symptoms of sphincter relaxation, coma, hypothermia, and organ function damage were more common in the shock group than in the non-shock group; and shock patients had longer hospitalization, ICU stay, and invasive ventilator use. Binary logistic regression analysis showed that the presence of sphincter relaxation manifestations ( OR=10.888, 95% CI: 1.677-70.684, P=0.012) was an independent risk factor for comorbid shock in patients with acute dichlorvos poisoning, and the use of cholinesterase reanimators ( OR=0.246, 95% CI: 0.072-0.846, P=0.026) was a protective factor for combined shock in patients with acute dichlorvos poisoning. Conclusions:The incidence of shock in patients with acute dichlorvos poisoning is high and affects the clinical prognosis, and the presence of sphincter relaxation and the absence of cholinesterase reenergizers are independent risk factors for combined shock in patients with acute dichlorvos poisoning.