1.Discussion about medical equipment file management
Chinese Medical Equipment Journal 1989;0(03):-
This paper introduces the definition, contents, methods and deficiencies for medical equipment file management in modern hospital. The importance of file management is also discussed.
2.Discussion on medical measurement control
Chinese Medical Equipment Journal 1989;0(04):-
This paper presents the definition,characteristics and significance of medical measurement control in modern hospitals.It also clarifies how to found a good medical measurement system.
3.Influences of sterile injector on infusion precision of syringe pump
Chinese Medical Equipment Journal 2015;(9):126-128
To explore the influences of the sterile injectors with different sources while the same capacity on the infusion precision of the syringe pump. With six injects with two brands were selected as the subjects and an electronic pump for measuring, flow test was carried out with the brands marked on the pump or not. There was significant difference between the flows from the syringe pumps marked with the injector brands and those without the mark of the brands. The sterile injector has to be set before using the syringe pump.
4.Ureteroscopy for the treatment of acute obstructive renal failure resulted from upper ureteral calculi
Jiangyong FAN ; Xiaojun CHEN ; Hongwen ZHU
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
Objective To investigate the advantages of emergent ureteroscopy for the treatment of acute obstructive renal failure resulted from upper ureteral calculi.Methods A total of 123 cases of acute renal failure caused by bilateral upper ureteral calculi was treated with ureteroscopic exploration,ballistic lithotripsy,catheter indwelling,and percutaneous nephrolithotomy.Results The serum BUN(blood urea nitrogen) and Cr(creatinine) were decreased to normal levels 2~10 days after operation in 100 cases(81.3%);the levels of Cr were maintained at 188.6~232.3 ?mol/L 10~15 days after operation in 22 cases.In 1 case of congenital solitary kidney(renal failure caused by chronic contralateral ureteral calculous obstruction),a hemodialysis was needed on the 3rd day after operation,and the serum Cr was 810 ?mol/L on the 15th day after operation and was dropped to normal after 2 months postoperatively.In 4 cases of previous unilateral nephrectomy or congenital solitary kidney,azotaemia remained at 3 months after operation.Conclusions Emergent ureteroscopy for acute renal failure caused by calculous obstruction possesses advantages of immediate obstruction relief,effective renal function protection,little trauma,low complication rate,and simple performance.
5.The new hypoglycemic mechanism and other effects of metformin.
Huanhuan CHEN ; Hongwen ZHOU ; Chao LIU
Chinese Journal of Practical Internal Medicine 2001;0(03):-
Metformin has been applied for 50 year.In recent years,new studies found that metformin could reduce glucose through activating inhibition of dipeptidyl peptidase Ⅳ(DPP Ⅳ) and enhancing the biological effect of glucagon-like peptide-1(GLP-1).In addition,metformin can reduce vascular disease risk of patients with type 2 diabetes by improving insulin resistance and the effect of reducing total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),blood coagulation factor Ⅶ,plasminogen activator inhibitor-1(PAI-1) and proteinuria.Merformin can't change blood pressure of patients with type 2 diabetes,however,it can significantly reduce the salt-sensitive blood pressure of patients with obesity.Metformin has also been applied to patients with polycystic ovary syndrome(PCOS).It can induce ovulation,decrease the rate of abortion and have effect on hypertrichosis and hyperandrogenism.Besides,metformin has been the focus of the treatment of non-alcoholic fatty liver disease.
6.Regulatory effects of insulin and glucose on aquaporin adipose expression in 3T3-L1 adipocytes
Hongwen ZHOU ; Yu DUAN ; Jiawei CHEN
Chinese Journal of Endocrinology and Metabolism 2001;0(05):-
Aquaporin adipose (AQPap) is the physiological glycerol channel specific to adipocytes. By means of semiquantitive RT-PCR and Western blotting, this study showed that insulin was a negative regulator of AQPap expression, while high concentration of glucose could increase AQPap expression.
7.Experience in posterolateral mini-incision total hip arthroplasty
Xiaosheng LI ; Tiezhu CHEN ; Hongwen CHEN ; Sihong LI
Journal of Central South University(Medical Sciences) 2013;38(12):1275-1281
Objective:To explore the surgical techniques in posterolateral mini-incision total hip arthroplasty and clinical effcacy.
Methods:A total of 94 patients (98 hips) had posterolateral mini-incision total hip arthroplasty, from December 2006 to December 2008, and were randomly divided into a posterolateral mini-incision total hip arthroplasty group (Group A) and a conventional group of posterolateral incision for total hip arthroplasty (Group B). Forty-nine patients (50 hips) in Group A had posterolateral small incision total hip arthroplasty [26 males, 23 females, between 37.0 and 95.0 years (average 68.9 years), body mass index (BMI) between 20.3 and 29.7 (average BMI 25.4)]. Forty-ifve patients (48 hips) in Group B had the conventional posterolateral incision [27 males, 18 females, between 45.0 and 92.0 years (average 69.7 years), BMI between 18.7 and 34.1 (average BMI 26.9)]. The incision length, blood loss, drainage, operation time, and postoperative Harris scores were compared between the 2 groups.
Results:The incision length was 6.0~10.5 (average length 7.4) cm, average blood loss was 387.6 (140.0~1000.0) mL, average drainage was 143.1 (63.0~375.0) mL, average blood transfusion was 77.6 (0~400.0) mL, average operation time was 84.6 (63.0~130.0) min, and vitalock abduction angle imaging after the operation was 41.6° (averagely 38.0°~57.0°) in Group A. The incision length was 15.0~23.0 (average length 20.0) cm, average blood loss was 513.1 (210.0~1350.0) mL, average drainage was 152.3 (70.0~520.0) mL, average blood transfusion was 142.2 (0~800.0) mL, average operation time was 84.0 (71.0~115.0) min, and postoperative radiographic acetabular cup abduction angle was 42.3° (37.0°~54.0°) in Group B. The follow-up showed that the prosthesis of the 2 groups was in a good position, Harris score was significantly improved with no complications after total hip arthroplasty in the 2 groups.
Conclusion:With the correct selection of indications and adept operation skills and other circumstances, posterolateral mini-incision total hip arthroplasty may do little damage to the soft tissue with a small scar on the skin. The imaging evaluation after the operation and the Harris score show no difference between the 2 groups. Patients are satisfied with their joint function and postoperative recovery.
8.Treatment of discoid meniscus injury by arthroscopic surgery
Xiaosheng LI ; Baotai YANG ; Tiezhu CHEN ; Sihong LI ; Hongwen CHEN
Clinical Medicine of China 2014;30(11):1208-1210
Objective To investigate the bettertherapeutic method and clinical efficacy of discoid meniscus injury under arthroscope.Methods Forty-one patients with discoid meniscus injury were selected as our subjects from Nov.2011 to Feb.2013,who were treated by arthroscopic surgery and performed with meniscus plasty.Thirt-eight patients were received ultra Fast-fix meniscal repair system.Joint function exercises were performed on bed within 1 month after operation.Incomplete weight bearing were performed after 1 month postoperation.After 3 month postoperation,they were permitted for full weight bearing.Results All patients were treated successfully with surgery and no postoperative complications occurred.The patients were followed up from 3.0 to 18.0 months and average was 10.5 months.The preoperative Lysholm scores were(68.28 ±8.04)) lower than that at the postoperation (88.17 ± 7.49)) and the difference were significant (t =11.59,P < 0.05).Furthermore,according to Ikeuchi criterion,the outcomes were 28 cases with excellent,10 cases with good and 3 cases with general rank.Conclusion Discoid meniscus plasty and suture under arthroscope is proved to be a better approach with less trauma,recovery quickly and fewer complications.It should be a preferred method for discoid meniscus injury.
9.The influence factor of 18F-FDG and 18F-FLT PET/CT for diagnosing pulmonary nodules
Yi CHEN ; Jihua ZHAO ; Liming MA ; Yu HONG ; Hongwen YANG
Journal of Chinese Physician 2008;10(6):761-763
Objective To evaluate the influence factor of 'SF-FDG and 18F-FLT PET/CT for diagnosing pulmonary nodules.Methods 55 patients with pulmonary nodules were chosen as study target,include 33 male cases and 22 female cases,the age range from 17 to 82 years old.In all cases,28 cases had one pulmonary nodule,others had 2 or 3 pulmonary nodules,and the nodule size was 0.6-11.0 cm.18F-FDG and 18F-FLT PET/CT were performed on 55 patients.The relationship of SUV of 18F-FDG and 18F-FLT with sex,age,size and pathology of all pulmonary nodule patients were analyzed.Results The SUV of 18F-FDG and 18F-FLT had no statistics difference on sex,age and size(P>0.05),the SUV of 18F-FDG had no statistics difference on pathology of pulmonary nodule(P>0.05).Otherwise,the SUV of 18F-FLT had statistics difference on pathology of pulmonary nodule(P<0.05).Conclusion The pathology of pulmonary nodule was an important influence factor for SUV of 18F-FLT,and the ~SF-FLT PET/CT has the high diagnostic effectiveness for pulmonary nodules and this method will has great influence on the clinical management of pulmonary nodule patients.
10.Pathogenicity of ureaplasma urealyticum serotype 3 in genital tract of mice
Hua LI ; Hongwen ZHANG ; Puxiang CHEN ; Liqiong WANG ; Lan GUO
Chinese Journal of Obstetrics and Gynecology 2009;44(3):204-208
Objective To study the pathogenicity of ureaplasma urealytieum serotype 3 (UU3) with different concentration in the genital tract of the mice. Methods A total of 156 Kunming mice were divided into 4 groups randomly, including group A, B, C (48 mice in every experimental group) and control group.(12 mice in control group). UU3 at concentration of 1×107eopy/g (group A), 1×106copy/g (group B),1×105copy/g (group C) were inoculated into 48 mice in every experimental group intravaginal]y, in the mean time, culture medium of UU was given into 12 mice in control group. They were neeropsied at 1, 3,7, 14, 21, 35 days of postinoeulatien randomly, which included 8 mice of every experimental group and 2 mice of control group every time, and to detect UU3 expression from cervical secretions by FQ-PCR andobserving the pathogenicity rate in tissues of cervix, endometrium, fallopian tube by light microscope and calculate the morbidity rate. Results (1) The total positive rates of UU3 were 63% (30/48) in group A,50% (24/48) in group B, 17% (8/48) in group C, which showed a significant difference(P<0.01).And at 1,3,7,14,21,35 days of postinoculation, the positive rates of group A were 8/8,7/8,6/8,5/8,4/8 and 0,group B were 7/8,5/8,5/8,4/8,3/8 and 0,group C were 3/8,2/8,2/8,1/8,0 and 0;all mice in control group were zero. At all time points, there were statistical difference in the positive rate among three experimental groups only at 1 day (P<0.05 ). (2) In the positive mice, their UU3 quantity concentration at 1,3,7,14,21 days were 1.70×107, 8.26×106, 4.04×106, 2.86×106,and 2.41 x105 copy/g in group A; 3.75×106, 2.56×106 , 1.37×106, 6.72×105, and 1.12 x 105 copy/g in group B, and 1.45×105,1.07×105, 5.43×104, 4.68×103, and 0 copy/g in group C. There were statistical difference among experimental groups at all time points except 21 days (P<0.05). Comparing the concentration among all time points of every group, both group A and B showed a significant difference(P<0.05) ,group C didn't reach it( P>0.05). (3) The total pathogenicity rates of three groups were significant different at 7-35 days, which were 56% (18/32) in group A, 44% (14/32) in group B, 6% (2/32) in group C (P<0.01 ). And at 7,14,21,35 days of postineculation, the pathogenicity rates in group A were 5/8,5/8,4/8 and 4/8, group B were 4/8,4/8,3/8 and 3/8, group C were 1/8,0,1/8 and 0; all mice in control group were zero, which demonstrated significant difference only at 14 days (P<0.05), no other statistical difference were observed (P>0.05) . Conclusions The pathogenicity of UU3 varies with different concentration in genital tract of mice. When UU3 concentration is more than 1×106 copy/g, the susceptibility to infection was intensified significantly.