1.Analysis of Infection-related Factors for Coronary Artery Bypass Grafting
Yingli ZHENG ; Li FANG ; Hongwei LI ;
Chinese Journal of Pharmacoepidemiology 2005;0(06):-
Objective:To analyze infection-related factors for Coronary artery bypass grafting(CABG).Method: The cases undergoing operations with CABG from January to June in 2006 were 614.The records of the two sets of statistical indicators were kept and the data were analyzed to find the infection-related factors.Result:There were three factors related to infection:the measure of anaesthesia,the time of hospitalization before surgical operations and the duration of prophylac- tic antibiotics treatment.Diabetes mellitus was not a risk factor in our study.Conclusion:In view of patients'health condi- tion,prophylactic antibiotics can be used to prevent infection in surgical operations.Shortening the time of hospitalization before surgical operations and adopting off-pump coronary artery bypass grafting can decrease the infection.CABG is as safe for diabetic patients as for non-diabetic patients.
2.Analysis of the significance of whole blood sample in the diagnosis of severe cases of hand, foot and mouth disease
Hongwei HAN ; Changchong LI ; Xiaoqing ZHENG
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):385-387
Objective To study the diagnostic significance of whole blood sample index in the severity of hand, foot and mouth disease, and to analyze its pathogenesis. Methods 194 cases of severe cases of hand, foot and mouth disease were selected as the case group,and 193 cases of mild hand, foot and mouth disease were selected as the control group. Blood samples were collected after admission to study the whole blood samples, including white blood cells, erythrocytes, platelets, medium cell ratio, lymphocyte ratio, mononuclear cell ratio, C-reactive protein test; The patient's immune system, the nervous system were also tested. Results Compared with patients with mild group, the white blood cell level of the patients in the severe group was higher and the albumin level was higher, the difference was statistically significant (P<0.05), the monocyte ratio, the T cell ratio was lower, the difference was statistically significant (P<0.05). Conclusion The white blood cell level and monocyte ratio of patients with severe hand, foot and mouth disease have changed. The whole blood sample has a certain sensitivity to the diagnosis of severe hand, foot and mouth disease.
3.Pedicle screw fixation for thoracic and lumbar diseases: a comparative analysis and prospects
Zheng LIU ; Hongwei LI ; Shuang WANG
Chinese Journal of Tissue Engineering Research 2017;21(19):3102-3107
BACKGROUND: Pedicle screw fixation is mainly used to treat thoracolumbar disorders, and accurate placement is the key to success; thereafter, how to improve the accuracy of placement and reduce the secondary nailing is an issue of concern.OBJECTIVE: To compare the advantages and disadvantages of various pedicle screw placement methods and their application value.METHODS: CNKI and PubMed databases were retrieved for clinical research concerning the pedicle screw fixation for thoracolumbar disorders published before May 2016 using the keywords of pedicle screw fixation, free-hand technique,3D-printing technology, computer navigation technology, clinical application prospect in English and Chinese,respectively. The repetitive literatures were excluded, and the advanced pedicle screw technologies were collected and evaluated in views of feasibility, universality and practicability.RESULTS AND CONCLUSION: (1) Computer-assisted navigation system and three-dimensional printing technology are the focus of research, but only applied in the treatment of pedicle congenital malformations or complicated cases. (2) Free-hand technique is still the most widely used, which is the essential skills that surgeons must master. (3) Traditional technology is still the mainstream in clinic, so improved preoperative planning, and individualized scheme are needed.
4.Study of 1000 Hz probe tone tympanometry on examination of fluid accumulation in tympanic cavity
Hongwei ZHENG ; Xingqi LI ; Lisheng YU
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(02):-
OBJECTIVE To analyze 1000 Hz probe tone tympanometry of middle ear with different volume of fluid, and to evaluate the role of 1000 Hz probe tone tympanometry in the diagnosis of presence of fluid in tympanic cavity. METHODS Tympanometries with 1000 Hz or 226 Hz probe tone were obtained from all the guinea pigs with different volume of fluid in tympanic cavity using GSI33 analyzer and tympanometry curves were analyzed. RESULTS There was a significant difference of the peak pressure of 1000 Hz tympanometry among all test groups and control group. The peak pressure decreased with the increasing of fluid volume in tympanic cavity. CONCLUSION Tympanometry with 1000 Hz probe tone can be used in the diagnosis of fluid in tympanic cavity, and it can be an indicator of volume of fluid in tympanic cavity.
5.The Correlation Between Age and Maximal Slow-Phase Velocity in Bithermal Caloric Test
Xin MA ; Hongwei ZHENG ; Lisheng YU
Journal of Audiology and Speech Pathology 1997;0(04):-
0.05).Conclusion The maximal slow-phase velocity induced by bithermal caloric test failed to decline with aging,implying that the functions of the horizontal semicircular didn't decline with aging.
6.Effect of continuous CO_2 pneumoperitoneum on tumor cell port site implantation in laparoscopic surgery in a murine model
Minhua ZHENG ; Hao WANG ; Hongwei LI
Chinese Journal of General Surgery 1997;0(06):-
Objective To determine whether the pressure of continuous CO 2 pheumoperitoneum (CCP) affects port site implantation of tumor cells.Methods Male SD rats were injected intraperitoneally with gastric cancer cells (cell line SGC 7901). Continuous CO 2 pneumoperitoneum at 15*!mm*!Hg or 30*!mm*!Hg for 5*!mins,60*!mins,120*!mins and 180*!mins with different number of tumor cell injection(10 4/ml, 10 6/ml respectively) was then established. Several samples of peritoneal washing served as positive control.All collecting dishes were incubated at 37℃ for one week.Results Dishes were tumor cell positive on which the tumor cells were collected from rats undergoing continuous flows of CO 2 gas (5*!L/min) at pneumoperitoneum of 30*!mm*!Hg for 60 mins or longer and all peritoneal washing samples showed tumor growth also. Conclusion It suggests that the number of tumor cells, pneumoperitoneum pressure and the duration may affect the port site implantation.
7.Evaluation of CTA for bronchial arteries in lung cancer and interventional therapy
Hongwei ZHENG ; Jianpin QI ; Xiaoming LI ; Hui DAI
Journal of Interventional Radiology 1994;0(03):-
Objective The application value of CTA for BA in interventional theray of lung cancer.Methods 15 patients with lung cancers including central type(13 cases)and peripheral type(2 cases) proven by pathology were analyzed prospectively.They were all examined with contrast enhanced.MDCT and the data were sent to the workstation and reconstructed with thin section multi-planar reformation(MPR),maximum intensity projection(MIP)and volume rendering(VR).Results All cases of central type lung cancer were supplied by the bronchial artery including two by the bronchial artery and intercostal artery,clearly demonstrated on the scans with the origin,branches and routes.One case of peripheral lung cancer was supplied by the bronchial artery and the other could not find the definite supplying artery.Conclusions CTA of BA for lung cancer can provide the accurate localization and other reference data for interventional therapy.
8.Effect of myocardial insulin resistance on expression of p38MAPK in ischemic heart failure in rat
Liling ZHENG ; Liangcai CHEN ; Weiping WU ; Hongwei CHEN ; Zhimeng ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2013;(3):169-171
Objective This study was carried out to investigate the effect of myocardial insulin resistance on expression of p38 mitogen-activated protein kinase (MAPK) in ischemic heart failure in rat.Methods Male sprague-dawley rats were subjected either to ligation of the left anterior descending artery (LAD) (n =24) or to sham operation (n =24).After two weeks,cardiac size and function were determined by echocardiography.Glucose and fatty acid (FAO) oxidation rates as well as insulin response were measured in the isolated working heart.The protein expression of p38MAPK was evaluated by Western blotting.Results The infarcted hearts were dilated and had a reduced ejection fraction (ejection fraction <0.50).The basal glucose oxidation was preserved,but the fatty acid oxidation was significantly reduced.Insulin effect on substrate oxidation was significantly impaired for both the decrease in fatty acid oxidation and the increase in glucose oxidation.The protein expression of p38MAPK in infracted hearts wasfisigni cantly reduced(P<0.05).Condusion Myocardial infarction in rats caused partial insulin resistance at the level of substrate oxidation,which was associated with cardiac contractile dysfunction and the expression of p38MAPK.
9.Research on Comprehensive Assessment Method of Mental Fatigue in Monitoring Task
Zheng WANG ; Yanjun LI ; Qu YAN ; Hongwei WANG
Space Medicine & Medical Engineering 2006;0(01):-
Objective To study the relationship between eye movement,HRV indexes and mental fatigue,find feasible objective indexes and build the comprehensive method to evaluate mental fatigue.Methods When twenty subjects executed the simulated monitoring task for 60 min,pupil diameter and ECG data were recorded by eye tracker system and Holter.The subjects were divided into 2 groups(fatigued group/scarcely fatigued group) according CFF(critical flicker frequency) and reaction time(RT).Based on comparison of various indexes between pre-and post-monitoring task,potent indexes were extracted to evaluate mental fatigue.Results After monitoring task,the change of fatigue feeling,Perclos,r-MSSD,PNN50,HF,LF and TP were significantly different in two groups.Conclusion It's suggested that psychology,Perclos and HRV indexes can be used to build the multilevel comprehensive method which can detect mental fatigue quantitatively and qualitatively.
10.Detection of CellularImmune Function in Syphilitic Patients and Its Clinical Significance
Qiutao LI ; Manyun FAN ; Qiutang ZHANG ; Xiaohong ZHENG ; Hongwei CAO ;
Chinese Journal of Dermatology 1995;0(03):-
ObjectiveTostudycellularimmunefunctioninpatientswithsyphilis.MethodsUsingflowcytometry,thecharacteristicofperipheralbloodlymphocyteimmophenotypes(PBLI)of23casesofsyphilis,andtherelationshipbetweenthePBLIandtherapeuticeffectwereanalyzed.Meanwhile,serumlevelofsIL-2Rofthepa-tientswasdetectedbyELISA.ResultsTheresultsshowedthatthepercentagesofpanT,TH,NKcellsandtheratioofTH/TSwerelower(P