1.Discussion on the Application of Economic Approaches for Environmental Health Impact Assessment
Journal of Environment and Health 1993;0(03):-
There are multiple sophisticated approaches that can be used in estimations on health effects resulting from environmental pollution. By comparison, human capital approach and averted expenditure approach are not suitable to be the first choice because of the insufficient capability of capturing all aspects of health effects. Date availability and estimation extrapolation limit the application of hedonic wage approach and hedonic price approach. It has been accepted universally for the flexible technique provided by contingent valuation approach that any health effects can be separately evaluated depending on researchers' purposes. Based on the powerful macroeconomic theory, general equilibrium theory, the CGE model is powerful to simulate the mechanism of interaction between multi-sectors with a national economic system so as to objectively reflect the health impacts on national economy due to environmental pollution.
2.The Assessment of Health Impact of Air Pollution on China's National Economy by Applying a Computable General Equilibrium Model
Hongwei YANG ; Yue WAN ; Masui TOSHIHIKO
Journal of Environment and Health 1993;0(03):-
Objective To establish computable general equilibrium model, CGE, and assess health impact of air pollution on national economy in China. Methods Based on the current concentration-response relationships provided by international and domestic epidemiological studies, the authors estimated the labor loss and excess medical expenditure led by China's air pollution, 2000. In order to elucidate the mechanism of the health impact on national economy, a computable general equilibrium model containing 39 sectors and 32 commodities was constructed for China. Results The simulation of the model indicated that the health impact due to air pollution has led to a GDP loss by 0.38‰ (95% CI 0.162‰-0.511‰) in China, 2000. Conclusion Air pollution not only has adverse effect on human health, but also retards the development of national economy.
3.Characteristics Analysis of Existing Integrated Environmental Assessments on Air Pollution-Induced Health Effects
Yue WAN ; Hongwei YANG ; Toshihiko MASUI
Journal of Environment and Health 1992;0(04):-
The existing frameworks of integrated assessment on air pollution-induced health effects can be classified into four types, i.e. U.S. EPA framework, U.S. Harvard University framework, Thailand framework and China framework. As the intention of integrated environmental assessment is to provide a scientific warranty for sustainable development-related policymaking process, the authors made a systematic review for the four types of integrated assessment framework. Not only the strong points and disadvantages in each type of framework were analyzed in detail, but also suggestions for future improvement in integrated assessment were put forward.
4.Study about the possibility of estimating firing distance of "5.4" hand gun according to the GSR
Hongwei LI ; Lihua WAN ; Zhihua MA
Chinese Journal of Forensic Medicine 1987;0(03):-
Objective To study the relationship between GSR and firing distance, and to discuss whether the relationship can be used to estimate the firing distance. MethodsShotting porkets with "5.4" hand gun at the firing distance of 5, 10, 15, 20, 30, 40, 50, 60, 70, 80, 90, 120cm respectively, then observing the distributing and element of GSR with SEM/EDX and finally building the equation of regression. ResultsThe relationship between the quantity of GSR and firing distance is linear and the equation is built. When the firing distance is from 10 to 90cm, the result is preferably. ConclusionWe can estimate the "5.4"hand gun firing distance through testing GSR around gunshot wounds.
5.Impact of consistency primary nursing model on improvement of obstetric nursing care quality
Hongwei WAN ; Yun LU ; Yanwen HOU ; Fei YU
Chinese Journal of Practical Nursing 2010;26(4):6-8
Objective The purpose of this study was to explore the impact of consistency primary nursing model on improvement of obstetric nursing care quality.Methods The sample consisted of 230 postpartum women in the intervention group and the other 240 postpartum women in the control group of non-intervention.The intervention is the use of new model of consistency primary nursing.Women finished the scale of overall patient satisfaction before their delivery.The other data of obstetric nursing care quality score were collected by study staff for three months.Data were analyzed using t test.Results Score of patients' overall satisfaction and obstetric nursing care quality in the invention group were much higher than that of the control group except for first-aid articles and disinfection and isolation.Conclusions The consistency primary nurs-ing model resulted in higher satisfaction and nursing care quality standard.It is suggested to extend this new nursing model in most maternity and infant hospitals and other general hospitals.
6.Activity and distribution of plasma platelet-activating factor acetylhydrolase in polycystic ovary syndrome patients with insulin resistance
Dehua WAN ; Ping FAN ; Huai BAI ; Qi SONG ; Hongwei LIU
Chinese Journal of Obstetrics and Gynecology 2010;45(1):30-34
Objective To investigate the relationship between activity of plasma platelet-activating factor acetylhydrolase (PAF-AH)and insulin resistance (IR) in patients with polycystic ovary syndrome (PCOS). Methods From Oct. 2006 to Jan. 2008, 105 PCOS patients undergoing treatment in Department of Obstetrics and Gynecology of Second Hospital affiliated to West China University were enrolled in the study, among 53 cases with homeostatic model assessment IR (HOMA-IR) exceed or equal 2.77 as IR-PCOS group and 52 cases with HOMA-IR less than 2.77 as non IR-PCOS group. In the mean time, 53 infertile women due to fallopian tube or husband factors were chosen as control group. Plasma PAF-AH activity, high-density lipoprotein-associated PAF-AH (H-PAF-AH) activity, low-density lipoprotein-associated PAF-AH (L-PAF-AH) activity, the ratio of L-PAF-AH to H-PAF-AH activity were measured and compared among three groups. The method of Pearson correlation analysis and stepwise multiple regression analysis were used to study the relationship between the ratio of L-PAF-AH to H-PAF-AH activities and hormonal and metabolic parameters. Results (1) Plasma PAF-AH activity [ (0.055±0.012) mmol· L~(-1)·min~(-1)], L-PAF-AH activity [(0.052±0.012) mmol·L~(-1)·min~(-1)], and the ratio of L-PAF-AH to H-PAF-AH activity (23±6) in the IR-PCOS group were significantly higher than those at control group [(0.050±0.009) mmol·L~(-1) ·min~(-1), (0.047±0.009) mmol·L~(-1)·min~(-1) and (18±4)] and non-IR-PCOS group [(0.050±0.0012) mmol·L~(-1) ·min~(-1), (0.048±0.012) mmol·L~(-1)·min~(-1) and (18± 5 ), P <0.05 ]. The ratio of L-PAF-AH to H-PAF-AH activities at IR-PCOS group was also significantly higher than those at Non IR-PCOS and control group after correction for body mass index (P<0.01). (2) Pearson correlation analysis showed that the ratio of L-PAF-AH to H-PAF-AH in PCOS patients was positively correlated with atherogenic index, age, body mass index, waist-to-hip ratio, HOMA-IR, triglyceride levels, fasting insulin levels, fasting glucose levels, low density lipoprotein cholesterol and total cholesterol (r=0.644, 0.247, 0.296, 0.212, 0.356, 0.587, 0.377, 0.375, 0.292 and 0.199, respectively, P<0.05), and negatively correlated with high density lipoprotein cholesterol (r=-0.510, P<0.05). The multiple stepwise regression analysis showed that atherogenic index and triglyceride were significant variables for the ratio of L-PAF-AH to H-PAF-AH activity (standardized coefficient, β=0.515 and 0.201, respectively, P<0.05). Conclusion The elvated L-PAF-AH activity may be associated with IR in PCOS patients, and the increased ratio of L-PAF-AH to H-PAF-AH activities may be a potential marker of inflammation in the patients.
7.Qualitative research of lived experience of infertile women who failed to in vitro fertilization treat-merit
Hongwei WAN ; Yun LU ; Yuehong LI ; Hongdi PENG
Chinese Journal of Practical Nursing 2009;25(14):23-26
Objective The purpose of this study was to explore the lived experience of infertile women who terminated treatment after in vitro fertilization (IVF) failure. Methods Using a qualitative research de-sign, 12 subjects were recruited who had experienced IVF failure for many times. Data were collected through deep interviews, and analyzed using interpretive research strategies of phenomenology. Results Informed consent was obtained from each subject. There were four themes of lived experience which emerged from the data: frustration, high pressure, giving up pregnancy, and replaning the future. Conclusions Infertile women who received in vitro fertilization treatment will eventually accept the reality and mark out their future life after experiencing hustrated sense and various pressure by failure treatment.Nurses should give more loving care and persuasion during this process.
8.Clinical outcome assessment and the effect measure
Hongwei ZHANG ; Jianping LIU ; Xia WAN ; Yanke AI
Journal of Integrative Medicine 2007;5(5):497-501
Effect of clinical intervention on human body is multistage and multifaceted, involving physiology, psychology, social function and the surrounding resources, etc. Therefore, the range of clinical outcome assessment includes patient, his or her family and care giver. The evaluation of clinical intervention mainly focuses on its effectiveness, safety and health economics. Effects of clinical interventions are measured by comparisons of the outcome of intervention and control groups. Different effect measures come from different comparisons.
9.Methods of selecting outcome variables for clinical intervention
Xia WAN ; Jianping LIU ; Hongwei ZHANG ; Yanke AI
Journal of Integrative Medicine 2007;5(1):11-4
Abstract: There are two stages for selecting the clinical intervention outcome variables. One is crude collection and the other is precise collection. The selection methods include brainstorming method, Delphi method, Gordon method, systematic review, systematic analysis method, mathematic model method and so on. Each method has some advantages or disadvantages. When selecting the clinical intervention outcome variables, researchers should make sure the research aim, the representative and the sensitivity of the variables, and select all kinds of recommended methods comprehensively, then decide which method should be used.
10.THE ASSOCIATION OF LIPOPROTEIN LIPASE GENE POLYMORPHISM WITH METABOLIC SYNDROME AND DIETARY PREDISPOSITION
Wentao WAN ; Hongwei GUO ; Kun XUE ; Shixiu ZHANG ; Xuan LUO
Acta Nutrimenta Sinica 1956;0(04):-
Objective To explore the genotype distribution of lipoprotein lipase gene polymorphism at Ser447Stop locus and its possible association with metabolic syndrome and dietary intakes. Method Ser447Stop polymorphism was determined by PCR-PFLP method in 222 adults with MS and 222 normal adults as control. Their physical examination,dietary investigation and levels of biochemical profile,including BG,TG,TC and HDL-C were analyzed. Results (1) The genotype frequencies of Ser447Stop SS,SX and XX were 85.6%,13.3% and 1.1% respectively,which were in agreement with Hardy-Weinberg equilibrium. There was no significant difference in frequencies of genotypes or allele between MS and the control,and between male and female. (2) After adjusting age and gender,the levels of serum TG were significantly different among three genotype groups,the highest in SS genotype and the lowest in XX genotype. (3) After adjusting age,gender and body mass index,the intakes of protein and carbohydrate were significantly different among three genotype groups. (4) There was significantly different in negative correlation between the intakes of protein and serum TG levels after adjusting age,gender and body mass index. Conclusion Lipoprotein lipase gene polymorphism influenced serum TG levels,while associated with protein intakes. It might contribute to the predisposition in metabolic syndrome response to dietary intervention.