1.The comparative study on TMJ radiographs of patients with posterior teeth-lose with or without TMD
Hongtao CAO ; Meiqing WANG ; Furong LIU
Journal of Practical Stomatology 2000;0(05):-
Objectives: To study the clinical meaning of condyle-form asymmetry and its osseous changes shown on TMJ images of lateral oblique transcranial projection and lateral tomography. Methods: 113 patients with partial posterior teeth lose were enroled in the study.Among them 25 were with temporomandibular disorder (TMD group),39 with slight TMD sings (sub-TMD group) and 45 without TMD(TMD-free group). Radiographs were taken and studied for each patient. Results: It was found that the condyle form asymmetry and osseous changes were not significantly different among the three groups. Osseous change was related to the number of teeth-lose (P0.05). The symptoms and signs of TMD had close relationship with occlusal interferences. Conclusions: The changes shown on TMJ images do not show close relationship with TMD symptoms and signs. Occlusal interferences resulted from teeth-lose are related to the clinical symptoms and signs of TMD.
2.Relationship between expression of alpha 2-HS-glycoprotein in placenta and insulin resistance in patients with gestational diabetes mellitus
Congming CAO ; Hongtao DING ; Miaorong LI
Chinese Journal of Postgraduates of Medicine 2014;37(27):7-9
Objective To investigate the relationship between expressions of alpha 2-HS-glycoprotein (AHSG) gene mRNA and protein in placenta and insulin resistance in patients with gestational diabetes mellitus (GDM).Methods The expressions of AHSG gene mRNA and protein in placenta were detected by reverse transcriptase-polymerase chain reaction (RT-PC R) and Western blot technique in normal uterogestation uterine-incision delivery patients (control group,43 cases) and patients with GDM (GDM group,45 cases).Fasting plasma glucose (FPG) and fasting insuhn (FINS) were detected before uterine-incision delivery,and the homeostasis model of assessment for insulin resistance index (HOMA-IR) was computed.Results The FPG,FINS and HOMA-IR in GDM group were significantly higher than those in control group [(5.28 ± 0.63)mmol/L vs.(4.24 ±0.21) mmol/L,(11.75 ±4.85) mU/L vs.(9.73 ±2.18) mU/L,2.79 ±1.02 vs.1.87 ± 0.66],there were statistical differences (P < 0.01 or < 0.05).The expressions of AHSG gene mRNA and protein in GDM group were significantly higher than those in control group (0.761 6 ± 0.069 1 vs.0.329 4 ± 0.025 1 and 0.824 5 ± 0.137 5 vs.0.420 3 ± 0.075 0),there were statistical differences (P< 0.01or < 0.05).HOMA-IR level in GDM group was positively correlated with AHSG gene mRNA and protein (r =0.633,0.587,P <0.05).Conclusions The expressions of AHSG gene mRNA and protein are significantly higher in patients with GDM.Insulin resistance may play an important role in the pathogenesis and development of GDM.
3.Continuing Activation of Caspase-3 Following Neonatal Rat Hypoxic-ischemic Brain Damage
Juli WANG ; Hongtao CAO ; Yukun HAN
Chinese Journal of Perinatal Medicine 2003;0(05):-
Objective To explore the role of caspase-3 activation and DNA fragmentation in later period of neonatal rat hypoxic-ischemic brain damage(HIBD). Methods DNA fragmentation,caspase-3 mRNA and caspase-3 protein were measured in 2 wks、3 wks and 4wks after setting HIBD animal model in newborn wistar rats by FCM, RT-PCR and Immunohistochemistry. Results (1) Apoptosis lasted 4ks after HIBD. This suggested a long lasting role of apoptosis in neonatal HIBD by TNNEL and EM.(2)Caspase-3 mRNA expression was estimated by semi-quantitative RT-PCR. It was higher in HIBD group(0.771?0.074) than in control group(0.620?0.038, P0.05. Average Avalue of Caspase-3 protein in HIBD group(0.374 ?0.038) at 3 wks was significantly higher than that in control group(0.356?0.020,P
4.Quantitative Analysis of Oleanolic Acid from the Fruits of Glossy Privet (Ligustrum lucidum) in Different Growing Periods
Hemin MI ; Yongbing CAO ; Hongtao SONG
Chinese Traditional and Herbal Drugs 1994;0(05):-
By means of TLC-densitomery, the contents of oleanolic acid extracted from the fruits of Ligustrum lucidum were determined to be 8.04% (g/g) in the unriped fruit collected in August and 2.73% (g/g) in riped fruit gathered in December. This result showed that the oleanolic acid content in fructus L. Iucidum decreases gradually with growing until the fruit is fully riped.
5.Management and Occupational Protection Against HIV/AIDS in Hospital
Huiying ZHU ; Xiaoyan WANG ; Hongtao CAO ; Yan WANG
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To enhance the management against the HIV and AIDS,strengthen the awareness of occupational protection among medical staff,and prevent the HIV spreads in the hospital.METHODS To establish the HIV/AIDS monitoring report management system,launching AIDS knowledge training,screening HIV seriously in hospital,sterilizing strictly with the medical instrument and managing the medical discards,and standardizing procedures of the medical nursing and process after the occupational exposing.RESULTS Through establishing the HIV/AIDS monitoring report management system and launching occupation protection training,the awareness of medical staff for precaution against the HIV/ AIDS was enhanced obviously.They could discover the patients early and take the effective measures for protection,sterilization and isolation in time.The average number of diagnosis days for HIV/AIDS patients shortened obviously than before.CONCLUSIONS Through enhancing management and supervision for HIV/AIDS in hospital,paying more attention to safety education for medical staff,we can prevent the AIDS spreading in the hospital and reduce the occurrence of occupational exposure among medical staff.
6.Development of constant-temperature-and-humidity test box used in medicament stability experiment
Yuzhen CAO ; Hongtao LIU ; Lixin ZHANG ; Wei WANG
Chinese Medical Equipment Journal 2003;0(12):-
This article introduces a constant-temperature-and-humidity test box, which, with a high-performance Aduc812 singlechip as the core, is composed of an integrated temperature and humidity sensor, a serial keyboard controller and a lattice-style liquid crystal module. With balance control mode of temperature an d humidity, PID control, temperature and humidity decoupling applied, the high-r esponse-speed and high-precision control can be fulfilled.
7.Methods and Experiences of Standardized Management for Rinse and Disinfection of Endoscope
Huiying ZHU ; Hongtao CAO ; Xiaohong RUAN ; Yan WANG
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To assure the medical safety,enhance the medical care,prevent medical infection by(endoscope) examination and do effectively the standardized management for rinse and disinfection of endoscope.METHODS Strengthening the organization,to establish and consummate the system,increase the devotion of(facilities,) organize personal training and standardize the work procedures.RESULTS The work for rinse and(disinfection) of endoscope in hospital came to be standardized management gradually.CONCLUSIONS The(standardized) management for rinse and disinfection of endoscope is the assurance for the validity and security of(endoscope) sterilization.
8.Clinical value of application of low dose scanning technology in the dual source CT coronary angiography
Zhiping ZHANG ; Hongtao HOU ; Guangzhao YANG ; Yulin CAO
Chinese Journal of Primary Medicine and Pharmacy 2017;24(17):2616-2619
Objective To observe the clinical value of application of low-dose scanning technology in dual source CT coronary angiography.Methods 200 cases who received coronary artery imaging were randomly selected as the study subjects.Patients were divided into the observation group and the control group using the random number method,100 cases in each group.All patients underwent dual source CT angiography.The observation group was treated by adaptive prospective ECG gated sequence,the control group was treated with retrospective ECG gated sequences.The image quality and radiation dose to bear were compared between the two groups.Results The various stages of image score proportion between the two groups had no significant difference(P>0.05).The average score of reading image of the observation group was (1.52±0.33)points,which of the control group was (1.48±0.46)points,there was no difference between the two groups(t=0.857,P>0.05).The CTDL,DLP and ED in the observation group were significantly lower than the control group[the observation group:CTDL(23.41±5.82),DLP(224.61±85.44),ED(3.01±1.12)mSv;the control group:CTDL(34.09±6.77),DLP(82.93±94.28),ED(5.33±2.01)mSv],and the differences were statistically significant(t=11.963,12.443,10.083,all P<0.05)].Conclusion Prospective ECG gated sequence technology can effectively reduce the radiation dose of the patients under dual source CT coronary angiography,reduce probability of radiation damage,and the image quality is not changed obviously,which meets the needs of clinical diagnosis.
9.The effect of occlusal disorder on the thickness of temporomandibular joint disc
Meiqing WANG ; Hongtao CAO ; Xiaodong LIU ; Junhua ZHANG
Journal of Practical Stomatology 2000;0(05):-
Objectives: To investigate the effects of cent ra l disordered occlusion on the thickness of TMJ disc. Methods:The thickness of temporomandibular joint disc was measured in 5 cadavers with centr al disordered occlusion, including secondary malocclusion caused by loss of post erior tooth for a comparable long time with collapse of neighbor teeth and supra -eruption of its antagonized tooth, the supra-erupted third molar resulted fro m lack of antagonized tooth for a comparable long time and individual posterior tooth cross bite or reverse cross bite asymmetrically. Other 7 cadavers without central disordered occlusion served as controls. All samples were examined histo logically for the TMJ disc thickness. Out of 18 New Zealand rabbits, aged 5 mont hs, 9 were treated orthodontically to pull the first premolar move medially, occ luding with its opposite un-coincidently, central disordered occlusion was grad ually induced. The other 9 rabbits served as blank controls. The TMJs were sampl ed 3 months after beginning of the experiments, stained with HE and observed und er microscope. Results: In both cadavers and animals, the TMJ di sc was found much thicker in central disordered occlusion group than that in the control group (P
10.Experience of Fusion image guided system in endonasal endoscopic surgery.
Jingying WEN ; Hongtao ZHEN ; Lili SHI ; Pingping CAO ; Yonghua CUI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(16):1431-1434
OBJECTIVE:
To review endonasal endoscopic surgeries aided by Fusion image guided system, and to explore the application value of Fusion image guided system in endonasal endoscopic surgeries.
METHOD:
Retrospective research. Sixty cases of endonasal endoscopic surgeries aided by Fusion image guided system were analysed including chronic rhinosinusitis with polyp (n = 10), fungus sinusitis (n = 5), endoscopic optic nerve decompression (n = 16), inverted papilloma of the paranasal sinus (n = 9), ossifying fibroma of sphenoid bone (n = 1), malignance of the paranasal sinus (n = 9), cerebrospinal fluid leak (n = 5), hemangioma of orbital apex (n = 2) and orbital reconstruction (n = 3).
RESULT:
Sixty cases of endonasal endoscopic surgeries completed successfully without any complications. Fusion image guided system can help to identify the ostium of paranasal sinus, lamina papyracea and skull base. Fused CT-CTA images, or fused MR-MRA images can help to localize the optic nerve or internal carotid arteiy . Fused CT-MR images can help to detect the range of the tumor. It spent (7.13 ± 1.358) minutes for image guided system to do preoperative preparation and the surgical navigation accuracy reached less than 1mm after proficient. There was no device localization problem because of block or head set loosed.
CONCLUSION
Fusion image guided system make endonasal endoscopic surgery to be a true microinvasive and exact surgery. It spends less preoperative preparation time, has high surgical navigation accuracy, improves the surgical safety and reduces the surgical complications.
Cerebrospinal Fluid Leak
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surgery
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Endoscopy
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instrumentation
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Fibroma, Ossifying
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surgery
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Humans
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Nasal Surgical Procedures
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methods
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Neurosurgical Procedures
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Nose
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pathology
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Papilloma, Inverted
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surgery
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Paranasal Sinuses
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pathology
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Retrospective Studies
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Sinusitis
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surgery
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Sphenoid Bone
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pathology
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Surgery, Computer-Assisted
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methods