Objective Hypoalbuminemia is a typical symptom of nephrotic syndrome ( NS) , which may result from the loss of much protein with urine.Hyperbilirubinemia is also a common symptom in patients with NS.This study is intended to reveal the relationship between hypoalbuminemia and hyperbilirubinemia in patients with NS by investigating urine bilirubin, albumin( ALB ) and 24-hour urine protein in the NS group, chronic glomerulonephritis ( CGN ) group and postoperative gastroparesis syndrome ( PGS) group ( ALB<35 g/L) .Methods Totally 187 patients with NS, 70 patients with CGN and 64 patients with PGS ( ALB <35 g/L ) were recruited before ALB, urinary protein ( UPR ) , urinary microalbuminuria/creatinine(Umalb/cr) and total bilirubin(TBIL) were detected.SPSS 17.0 Software was used to analyze the difference between the three groups and to reveal the correlations between TBIL and UPR, ALB.Results TBIL, ALB, UPR and Umalb/Cr levels were significantly different between NS, CGN and PGS groups ( one-way ANOVA test, P <0.05), and TBIL was positively correlated with ALB but negatively correlated UPR and Umalb/Cr in both NS and CGN groups (Spearman′s rho test,P<0.05);but no correlation was found between these items in PGS group (Spearman′s rho test,P>0.05) .Conclusion Serum bilirubin of patients with NS is at a low level and shows significant correlations with serum albumin and urinary protein levels.No similar association is found with the other two groups.The results in this study show that the causes of low serum bilirubin in patients with NS may related to the large amount of protein lost in urine.

Objective:To explore the effect of goal-oriented rehabilitation exercise in postoperative nursing of elderly patients with femoral neck fracture.Methods:From August 2019 to August 2021, 90 elderly patients with femoral neck fracture who were admitted to the Department of Orthopedics of the First Affiliated Hospital of Zhengzhou University were selected by convenient sampling as the research object. The patients were divided into control group and observation group according to the method of random number table, 45 cases in each group. The control group adopted conventional nursing, while the observation group implemented goal-oriented rehabilitation exercise on the basis of the control group. The Function Independent Measure (FIM) and the Europe Health-related Quality of Life Questionnaire-5 Dimension (EQ-5D) were used to evaluate the two groups of patients to compare the motor function and quality of life before and after the intervention.Results:After intervention, the scores of motor function and cognitive function and total scores in FIM in the control group were lower than those in the observation group, with a statistically significant differences ( P<0.05) . The scores of mobility, self-care and usual activities in EQ-5D in the control group were lower than those in the observation group, and the scores of pain/discomfort and anxiety/depression were higher than those in the observation group, with statistically significant differences ( P<0.05) . Conclusions:The goal-oriented rehabilitation exercise can improve the exercise ability of elderly patients with femoral neck fracture, promote the quality of life, and facilitate rapid rehabilitation of patients.