2.A curative efficacy study of functional training focusing on muscle group around shoulder for subacromial impingement syndrome
Chinese Journal of Rehabilitation Medicine 2017;32(5):543-547
Objective:To study the curative efficacy of functional training focusing on muscle group around shoulder for subacromial impingement syndrome.Method:Forty five patients with subacromial impingement syndrome (SIS) were randomly grouped into three groups (fifteen patients for each group).Patients in Group Ⅰ were trained only on muscles around scapula.Patients in Group Ⅱ were treated on rotator cuff muscles.While patients in Group Ⅲ were treated on both.The training goes every 2 days and last for 4 weeks.The indexes for evaluating curative efficacy included:the Neer-test,the Hawkins-test and the Peen Shoulder Score.These indexes were measured immediately and three months after the four week treatment.Result:After treatment of the functional training focusing on muscle group around shoulder,Neer-tests and Hawkins-tests of all of patients were changed from positive to negative,the degree of pain compared with pain before the treatment declined apparently(P<0.01),at the same time,the degree of satisfaction and the function went up remarkablely(P<0.01).Compared with group Ⅰ and group Ⅱ,it dropped the most notably on the degree of pain in the group Ⅲ(P<0.01),however,the degree of satisfaction and the function rose most apparently (P<0.01) Conclusion:The curative efficacy of functional training focusing on muscle group around shoulder for sub-acromial impingement syndrome was effective apparently.But the efficacy of treated focusing on both muscles around scapula and rotator cuff was the most remarkably.
3.Immunomodulatory activity of cancer chemotherapy
Jie LI ; Hongsheng LIN ; Guizhi SUN
Cancer Research and Clinic 2010;22(1):70-72
In addition to kill tumor cells through direct cytotoxicity, the immunomodulatory activity is another facet of chemotherapy. The major molecular mechanisms of immunogenicity of cytotoxic drugs are elimination of CD_4~+ CD_(25)~+ regulatory T cells or Myeloid-Derived Suppressor Cells, and sensitization of tumor cells to immune effectors through modulation of death receptor expression. These studies provide scientific evidence for combinatorial treatments including vaccines and Traditional Chinese Medicine for cancer therapy.
4.Clinical application of spinous process forming in posterior lumbar interbody fusion
Guowei ZHANG ; Hongsheng LIN ; Zhenggang ZHA
Orthopedic Journal of China 2006;0(15):-
[Objective]To explore the feasibility and clinical effects of spinous proscess forming in posterior in the treatment of lower lumbar diseases. [Methods]Seventy-seven cases suffered from lower lumbar diseases were treated using spinous proscess forming as interbody fusion material.The cases included 35 of lumbar disc herniation,21 of spondylolysis,11 of degenerative spondylolisthesis and 10 of spinal canal stenosis.The clinical data and imaging results were investigated.[Results]Seventy-two patiens were followed up for 1 to 2 years while 5 were lost.During following-up,no loosened internal fixation,broken nail or stick,infravertebra prolapsed,or detachment recurrence was found.Preoperative the height of intervertebral space was 8.5?1.9 mm,10.9?1.8 mm at 2 weeks postoperatively and was 10.7?1.7 mm at last follow-up.The height of intervertebral space were significantly increased postoperatively with statistically significant difference(P
5.Replacement of humeral head prosthesis for complex fractures of proximal humerus
Hongsheng LIN ; Zhengang ZHA ; Guopu WANG
Chinese Journal of Trauma 2003;0(07):-
Objective To investigate the clinical value and relating problems in treating complex fractures of proximal humerus by using replacement of humeral head prosthesis. Methods There were 23 cases (10 males and 13 females, age range 43-76 years, mean 58.6 years) with complex fractures of proximal humerus. According to Neer classification, 4 cases had three-part fracture, 17 four-part fracture, 2 cleavage fracture of humeral head, 18 fresh fracture (within 2 weeks after injury) and 5 old fracture, which were all treated with replacement of humeral head prosthesis. Results Follow-up study for a mean period of 15.6 months was conducted in all the cases. No flexible prosthesis, prosthesis dislocation, infection, nerve damage or periprosthesis fractures occurred. According to scoring system modification for hemiarthroplasty (SSMH) of UCLA (Los.Angeles, California, USA), the average score was 26.3. Score was above 27 (excellent) in 3 cases and 24-27 (good) in 18 with an excellence rate of 91.3%, score was 18-24 (moderate) in 2 but no one had score less than 18. Average score was 9.5 in pain, 8.6 in function and 8.2 in muscle power and motion in 23 cases. Conclusions Replacement of humeral head prosthesis is a preferable method for treating the complex fractures of proximal humerus, with significant effect in relieving the pain in the shoulder joint posterior to trauma. It is key to a satisfactory curative effect to correctly select the indication, clearly master the local anatomy, grasp the operation technique and give early and reasonable postoperative rehabilitation treatment.
6.The effect of TCM method of regulating liver Qi and tonifying kidney Yin on plasma concentration of E2, P and FAS of post-surgery breast-cancer patients received endocrine therapy (Tamoxifen)
Peiyu ZHANG ; Wenping LU ; Hongsheng LIN
International Journal of Traditional Chinese Medicine 2010;32(5):398-399
Objective The prospective study was trying to explore the altering tendency of plasma concentration of E2, P and PAS after TCM intervention for post-surgery breast cancer patient who received endocrine therapy (tamoxifen).Methods By randomization, parallel, coincidence measures and the lab. technologies of AXSYM registered at Abbott lab. in the USA, plasma concentration of E2, P and FAS were tested before and after treatment. Results The results of biochemical test of plasma E2, P and FAS concentration of the two arms showed no significance difference before and after the intervention,indicating the side effects relating to TAM had nothing to do with plasma E2, P and FAS level. Conclusion It could be predicable that there must be some other by-pass ways initiating breast cancer rather than the way directly altering the level of plasma concentration of E2, P and FAS.
7.Treatment of thoracolumbar vertebrae fractures with fixation by vertebral pedicle screw system and vertebroplasty using injectable graft
Hongsheng LIN ; Zhengang ZHA ; Weizai SHENG
Orthopedic Journal of China 2006;0(12):-
[Objective]To discus clinic value of fixation by vertebral pedicle screw system and vertebroplasty using injectable graft for thoracolumbar vertebrae fractures.[Method]Fifteen cases of thoracolumbar vertebrae fractures(7 cases with compress fractures,8 cases with burst fractures) were treated with fixation by vertebral pedicle screw system and vertebroplasty using injectable graft.[Result]The group was followed up for average 9.6 months,no case showed internal fixation device loosening or breaking,nor were chronic lumbar pain seen in this group.No case had lost the anterior height of body of spine.All injected grafts were Abs orbed within 3 months postoperatively.According to Frankels grading,there were 4 cases in Grades B,6 cases in Grade C and 2 cases of Grade D preoperatively,but 3 cases of Grade C,5 cases of Grade D and 4 cases of Grade E postoperatively in 12 cases with incomplete paraplegia,with a statistically significant difference(x~2 =21.000,P=0.000
8.The Clinical Study on Management of Side effects of Endocrine Therapy (Tamoxifen) on Breast Cancer Patients in Post Surgery with TCM Treating Principle of Regulating Liver Qi and Tonifying Kidney Yin
Peiyu ZHANG ; Wenping LU ; Hongsheng LIN
International Journal of Traditional Chinese Medicine 2009;31(4):309-311
Objective By previous overview of patients treated in our hospital, this study highlights on the intervention effects of TCM treating principle of regulating liver Qi and tonifying kidney Yin on the adverse reaction of TAM on breast cancer patients in post surgery. Methods Perspective study with the measures of randomization, and paralleling and synchronization control was conducted in the research. Results symptoms such as flush, insomnia, night sweat, palpitation, depression and heat sensation in the chest, palms and soles were improved significantly; while manifestations such as nausea, vomiting, irregular menstruation, bitter taste and dry mouth showed no significant changes. QOL changed significantly. Conclusion The application of treating principle of regulating liver Qi and tonifying kidney Yin is effective in reducing side effects caused by TAM. This result further improved the theory of TCM that the nature of liver is active, although the liver belongs to Yin in physique and but Yang in function.
9.The current application and prospect of classical prescription in lung cancer treatment
Huiyong YU ; Qi ZHENG ; Qi LI ; Hongsheng LIN
International Journal of Traditional Chinese Medicine 2016;38(8):761-764
The classical prescriptions in Typhoid Miscellaneous Disease can be used to alleviate the common hung cancer symptoms and complications like fever, cough, pain and pleural effusion effectively. The preoperative medication can improve lung cancer patients’ surgical tolerance, and postoperative medication can facilitate patients’ postoperative rehabilitation. And if combined with chemotherapy, they cound reduce toxicity and enhance efficiency, enhance the patients’ immunity and improve their life quality. Research shows that classical prescriptions can improve the immunity of lung cancer model mice, facilitate apoptosis of tumor cell and control its migration. This paper sumed up the clinical and experimental research of lung cancer treatment with classical prescriptions in recent 5 years.
10.The inhibitory effect of Chinese medicine Jinan injection on Lewis lung cancer in mice
Caihong ZHOU ; Hongsheng LIN ; Qifu HUANG ; Yingxia PEI ; Xi QI
Chinese Journal of Pathophysiology 1989;0(05):-
AIM: To investigate the inhibitory effect of Chinese medicine Jinan injection(JA) on Lewis lung cancer (LLC) in mice. METHODS: The C 57 BL/6J mice with Lewis lung cancer(LLC) were divided into normal saline(NS), Jinan high dose (JAH), Jinan middle dose (JAM), Jinan low dose (JAL) and cyclophosphamide(CTX) groups. The body weight changes and inhibitory rate of LLC in each group were observed. In addition, flow cytometry and TUNEL were used to detect the anticancer mechanism of Jinan. RESULTS: The body weights were increased significantly in JA-treated groups vs CTX and the resistant rate was 45.79%, 40.90%, 32.48% and 98.96%, respectively. The apoptotic rate was 24.19%, 14.95% and 13.93% in JAH, JAM and JAL, respectively, and the Jinan induced apoptosis of LIC in a dose-dependent manner.CONCLUSION: Jinan injection inhibites the growth of LLC, and the apoptosis induction may be one of mechanisms that Jinan treates LLC in mice.