1.Influences of medical equipment market on purchase risk
Hongpeng ZHANG ; Dan ZHOU ; Mihui HE
Chinese Medical Equipment Journal 1989;0(04):-
This paper uses defense acquisition theory to research on the problem of military medical equipment purchase.Focusing on the risk problem of military medical equipment purchase,this paper firstly introduces the current status of military medical equipment purchase.Then it analyses the effection of oligopoly to purchase risk based on oligopoly making price theory.At last,it puts forward some proposals for avoiding the risk of military medical equipment purchase.
2.Prognostic value of plasma D-dimer level in patients with advanced non-small-cell lung cancer and its rela-tion with pulmonary embolism
Jiali WANG ; Kaifen YUAN ; Hongpeng ZHANG
Journal of Medical Postgraduates 2016;29(8):849-852
Objective Non small cell lung cancer( NSCLC) is a common tumor and the blood of NSCLC patients is generally in a state of high coagulation.However, as a predictor of coagulation, few study has been done on the role of D-dimer level in lung cancer.This article aimed to analyze the prognostic value of plasma D-dimer level in patients with advanced NSCLC and its relation with pulmonary embolism Methods The study collected patients with lung cancer treated in Tianjin Chest Hospital from January 1, 2013 to October 31, 2015.The serum levels of D-dimer were measured by enzyme-linked immunosorbent assay.Based on different lev-els, the patients were divided into high expression group and normal expression group.The relationship between D-dimer level and the prognosis of lung cancer patients were analyzed by Kaplan-Meier method and Log-rank test univariate analysis.T test was used to ana-lyze the difference of D-dimer between patients with and without pulmonary embolism. Results In all the enrolled subjects,103 ca-ses (73.75%) of plasma D-dimer were normal, while 37 patients (26.25%) were elevated.Survival analysis showed that the patho-logical status, tumor size and D-dimer were independent prognostic factors; and the D-dimer in patients with pulmonary embolism was 5.37 ±1.23 μg/mL, while the patients without pulmonary embolism was 0.43 ±0.73μg/mL, D-dimer in patients with pulmonary embol-ism was high than the patients without pulmonary embolism, showing significant difference (P<0.05). Conclusion Plasma D-dimer is an independent prognostic factor for the prognosis of lung cancer, which is obviously higher in patients with lung cancer and pulmonary embolism than in patients without pulmonary embolism.
3.Study of the exression and clinical significance of HGF,MMP-2 and MMP-9 in pancreatic carcinoma
Hongpeng ZHAO ; Yinlu DING ; Jianliang ZHANG
Chinese Journal of Current Advances in General Surgery 1998;0(01):-
Objective:To study the expression and significance of HGF, MMP-2 and MMP-9 in pancreatic carcinoma. Methods:The expression of HGF, MMP-2 and MMP-9 were examined by immunohistochemical technique in 50 cases of pancreatic carcinomas and 10 cases of normal tissues. The relationship between the expression and tumor behaviors were also analyzed. Results:The expressions of HGF, MMP-2 and MMP-9 in pancreatic carcinoma and normal tissues had distinct differences (P
4.Experiences on Endovascular Aortouniiliac Repair Combined with Cross-Femoral Bypass Grafting for Abdominal Aortic Aneurysm
Hongpeng ZHANG ; Wei GUO ; Xiaoping LIU
Chinese Journal of Minimally Invasive Surgery 2001;0(02):-
Objective To evaluate the efficacy of endovascular aortouniiliac repair (EVAR) combined with cross-femoral bypass grafting (CFBG) for the treatment of abdominal aortic aneurysm (AAA). Methods From May 1997 to February 2007, 8 patients with AAA, in whom bifurcated stent-graft could not be used because of complex iliac anatomy, were treated with EVAR using AUI stent-graft combined with CFBG. The endoleak, ischemic syndromes,patency of the bypasses, and blood supply of the lower limbs were observed after the operation. Results There were no perioperative mortalities in this series. One patient died of myocardial infarction 15 months after the operation. Three patients developed primary endoleak, and was cure spontaneously 1, 3, and 6 months postoperation. The 8 patients were followed up for a mean of 24 months (3-72 months), during which the patency rate of cross-femoral bypass was 100%. One year after the operation, 1 patient developed mild anastomotic stoma stenosis without ischemia of the lower limbs, but no limb ischemia. Conclusion In patients with complex iliac anatomy unfavorable for bifurcated endografting, EVAR using AUI combined with CFBG is safe and effective.
5.Risk Management in Medical Equipment Purchase
Dan ZHOU ; Guangze LU ; Hongpeng ZHANG
Chinese Medical Equipment Journal 1989;0(03):-
Objective To study the characteristics of the procedure of medical equipments purchase.Methods The risk of medical equipment purchase was analyzed.Results Methods of how to avoid this risk was put forward,such as loan in hospital,project management and a series of check and analysis procedures.Conclusion Desirable economic benefit and effective management are achieved.
6.Protective effects of Clara cell secretory protein on lung injury in traumatic shock model
Hongpeng ZHAI ; Chunyang ZHANG ; Jian ZHANG ; Jinhui LI
Chinese Journal of Biochemical Pharmaceutics 2014;(3):61-63
Objective To investigate the effect and mechanism of Clara cell secretory protein (CC16 ) on lung injury of traumatic shock rats.Methods Thirty SD male rats were randomly assigned to three groups:sham-operation group,control group and CC16-treatment group.The rat model of traumatic shock was used in this study.Rats of sham-operation group were operated,but not treated by depletion and recovery.Rats of control group inhaled the physiological saline before fluid resuscitation.Rats of CC16-treatment group inhaled 0.1 μg/mL of recombinant human Clara cell secretory protein (rh-CCSP)before fluid resuscitation.Arterial blood gas analysis and wet/dry weight were detected in each group.The contents of malondialdehyde (MDA),myeloperoxidase (MPO)of lung tissues and lung tissue pathology changes were also studied. Results Compared with control group,pH and PaO2 value in CC16-treatment group increased significantly.Meanwhile,BE value and lung wet/dry weight ratio also decreased significantly (P<0.05).Compared with control group,contents of MDA and MPO in CC16-treatment group decreased significantly (P<0.05).Lung tissue pathology improved in the CC16 group compared with that of control group (P <0.05 ).Conclusion Inhaled Rh-CCSP may have potential protective effect on lung injury tissues of traumatic shock rats model through its antioxidative effect.
7.The influence of high ligation of the inferior mesenteric artery on anastomotic leakage after rectal cancer resection
Guangjun ZHANG ; Shusen XIA ; Zuoliang LIU ; Hongpeng TIAN ; Tong ZHOU
Chinese Journal of General Surgery 2013;(2):90-92
Objective To identify risk factors for anastomotic leakage,and study the influence of high ligation of the inferior mesenteric artery on anastomotic leakage after rectal cancer resection.Methods The chi-test and the student t test were used for statistics.Clinical data were analyzed for 291 patients who underwent rectal cancer resection between August 2008 and November 2011.Results Anastomotic leakage occurred in 27 (9.3%) patients.Anastomotic leakage significantly increased in patients with tumours located within 10 cm from the anal verge,in male patients,and intraoperative blood loss.The use of high ligation of inferior mesenteric artery,which was associated with lower tumor location and surgical modality,was not a risk factor for anastomotic leakage,though it was associated with tumor stage and postoperative urinary retention.Conclusions Anastomotic leakage after rectal cancer resection is related to the tumor level,male gender,and perioperative bleeding,use of a high tie was not associated with an increased rate of symptomatic anastomotic leakage.
8.Endurant stent-graft for the treatment of abdominal aorta aneurysm
Xin JIA ; Wei GUO ; Xiaoping LIU ; Jiang XIONG ; Xiaohui MA ; Hongpeng ZHANG ; Xin DU ; Minhong ZHANG
Chinese Journal of General Surgery 2011;26(11):904-906
Objective To evaluate early results of Endurant stent-graft in the treatment of abdominal aortic aneurysms (AAAs).Methods From July 2010 to June 2011,68 patients (57 men,11 women; mean age 74.3 years) were treated with Endurant stent-graft at our center.26 cases had hostile proximal neck in the anatomy.According to ASA classification,15 cases were class Ⅱ ; 32 cases were class Ⅲ and 21 cases were class Ⅳ.Results Intraoperative immediate technical success was achieved in all cases.At completion angiography,a type Ⅱ endoleak was detected in 18 (26%) of the 68 patients.The mean operation time was (96 ± 29) min,the mean blood loss was (99 ± 68 ) ml,and the mean contrast usage was (122 ± 65) ml.No intraoperative conversion to open surgery,stent migration,types Ⅰ/Ⅲ endoleak,other major complications,or death was encountered.49 patients (72%) had a postimplantation syndrome with fever,leukocytosis,and increase of C-reactive protein levels,which completely resolved within two weeks.The mean follow-up time was (8 ± 5) months.Conclusions Endurant stent-graft seems to be safe and effective in endovascular aneurysm repair,even in patients with hostile aortoiliac anatomy.
9.Remedial surgical therapies after endovascular repair of aortic dissection
Xiaohui MA ; Wei GUO ; Xiaoping LIU ; Xin JIA ; Jiang XIONG ; Hongpeng ZHANG ; Xin DU ; Minhong ZHANG
Chinese Journal of General Surgery 2012;27(7):539-542
Objective To probe into the reasons for and results of remedial surgical therapy in thoracic aortic dissection patients after first endovascalar repair.Methods From July 2000 to December 2012,12 cases received second interventional surgery.The average time from second therapy to first surgery was ( 14 ± 11 ) months.Main reasons for second endovascular therapy were sustained type Ⅰ endoleak at proximal landing zone and type A dissection caused by retrograde tear.Therapies included hybrid operations in 8 cases and absnlute endovascular therapy in 4 cases.Results The 30 day mortality after the second intervention was 5.6% ( 1/12),total mortality rate was 16.7% (2/12).In 7 cases with endoleak,small endoleak remained after remedial therapy (57.1% ) in 4 cases.Among 4 cases with secondary type A aortic dissection,successful staged hybrid operation with mid-sternal thoracotomy was adopted in 3 cases,one died of pulmonary emtbolism during follow-up period,1 case with Bebcet disease still had proximal type Ⅰ endoleak after second hybrid operation,and died from tear of aorta.Conclusions Endoleak and secondary type A aortic dissection are the main cause necessitating second intervention after primary endovascular therapy for thoracic aortic dissection.Hybrid operation remains the best choice to treat postoperative complications after endovascular therapy for thoracic aortic dissection.
10.The influence of hostile neck anatomy on endoleaks after endovascular aneurysm repair
Hongpeng ZHANG ; Wei GUO ; Xiaoping LIU ; Xin JIA ; Jiang XIONG ; Xiaohui MA ; Minhong ZHANG ; Yongle XU
Chinese Journal of General Surgery 2012;27(7):523-526
Objective To determine the influence of hostile neck anatomy on type Ⅰ a endoleak development after endovascular aortic aneurysm repair (EVAR) for infrarenal abdominal aortic aneurysmal disease.Methods From July 2008 to July 2011,195 consecutive patients with non-ruptured abdominal aortic aneurysms (AAA) were treated with EVAR.There were 150 males and 45 females,aging from 52 to 95 years with a mean of 69 years.Forty-three patients were with hostile neck anatomy ( HNA ).High-resolution computed tomography was abtained in all patients,with detailed measurement of proximal neck parameters.Univariate and multivariate analyses were used to compare Ⅰ a endoleak and HNA.Follow-up protocol consisted of computed tomography (CT) angiograms or ultrasound at 3,6,and 12 months,and annually thereafter.Results Twenty-three patients had intraoperative type Ⅰ a endoleaks.The adjunctive measures,such as repeated balloon angioplasty,cuff extension,Palmaz stent placement and chimney technique were used for treating type Ⅰ a endoleak.Small endoleak remained in only one patient.The technical success rate was 98.5% (192/195).The association between type Ⅰ a endoleak development and magnitude of the infrarenal angle was statistically significant.The mean follow-up time was ( 18 ± 3 )months.The survival rates at 1- and 3-year were 97.4% and 89.2% respectively.Conclusions The proximal neck angle is related to intraoperative type Ⅰ a endoleak occurrence,but other factors often thought to be indicative of adverse neck anatomy are not significant predictors.Most type Ⅰ a endoleaks in this study were uccessfully eliminated intraoperatively with a satisfactory mid to long term results.