1.Intravascular Stent Insertion for Treatment of Inferior Vera Cava Obstruction
Yongjie WANG ; Hongming WANG ; Xiangyang WANG ;
Journal of Interventional Radiology 1994;0(04):-
8 cases of inferior vena cava obstruction were treated with intravascular stent insertion,including 3 membranacous obstructions and 5 segmental obstructions.All 8 cases obtained successful results without Severe complications.4 cases were checked up half a year later(2 of which were to checked after one year)with stents still in position and pa- tency of all.inferior vena cavas.In present studies the insertion technique and prevention of complication were discussed.
2.Percutaneous Lung Cancer Cryotherapy (PLC) by Computer Tomography Guidance
Hongwu WANG ; Hongming MA ; Hong LI
Journal of Medical Research 2006;0(02):-
Objective To document the feasibility and safety of percutaneous lung cancercryotherapy(PLC)guided by Computer Tomography(CT).Methods 798 CT-guided PLCs in 634 cases with lung cancer from August,2001,to April,2006.CT-visualized immediate ice formation beyond tumor margins was compared to tumor size and location.PLC feasibility and safety was evaluated for the complications postcryoablation.Results All the patients underwent PLC using local anesthesia with minimal or no sedation.Iceball formation was well seen as negative Hounsfield units within soft tissue masses.Tumor size and location were independent determinants of ice coverage:96.4%(n= 343)for masses 4 cm in diameter(P
3.The application of indirect laryngoscope in the young child with adenoidectomy
Shuxuan LU ; Hongming WANG ; Shunming JIANG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(10):1458-1459
ObjectiveTo explore the effect of the indirect laryngoscope in the young child adenoidectomy.Methods35 young children with adenoidoctomy were given the general anesthesia and the suspension of soft palateby catheter,looking straight ahead under the indirect laryngoscope,the large adenoid body was cutted and attracted.ResultsAftersurgery,both the snort and suppressed breath symptoms were improved significantly,none complication occured.ConclusionUnder the indirect laryngoscope,adenoidectomy was not only safe and effective but also easy,feasible and economical.
4.Maxillary ameloblastic fibroma: a case report.
Hongming WANG ; Weishuang XUE ; Aihui YAN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(23):1335-1336
Ameloblastic fibroma (AF) is a benign tumor, it is a true mixed tumor composed of neoplastic epithelium and mesenchymal. This tumor is rare, and it almost arises in the mandible. A 22-years old female patient referred AF in the maxillary was present. The tumor was asymptomatic, except the right facial bulge. The radiograph showed a well-circumscribed neoplasm with several low density cysts involving the right maxillary and ethmoid. The lesion was enucleated and the material was sent for histopathologic examination. Microscopically, it was composed epithelium and mesenchymal with histopathological diagnosis of ameloblastic fibroma.
Ameloblastoma
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Female
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Humans
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Jaw Neoplasms
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Young Adult
5.Efifcacy of thalidomide combined with VAD in treatment of Elderly multiple myeloma and its adverse reactions
Shuang HUI ; Bo WANG ; Yuan WANG ; Wenlian WANG ; Hongming HUANG
Chinese Journal of Biochemical Pharmaceutics 2014;(2):90-91,94
Objective To investigate the efifcacy of thalidomide combined with VAD in treatment of elderly multiple myeloma(MM). Methods 76 cases of elderly MM were randomly divided into two groups, control group (n=38) were treated with VAD alone while the observation group (n=38) were treated with thalidomide and VAD. Clinical efifcacy and adverse reactions in two groups were compared. Results The total effective rate in observation group was 84.21%, which was signiifcantly higher than 55.26%in control group (P<0.05). After treatment, the M protein, myeloma cells andβ2-microglobulin in observation group were (20.77±4.15)×10-2μg/mL, (12.84±2.85)×10-2μg/mL and (2.48±0.53)μg/mL, which were signiifcantly lower than before treatment and control group(P<0.05). Hemoglobin in observation group was (108.83±5.81) g/L, which was signiifcantly higher than before treatment and control group(P<0.05). The adverse reactions were nausea, vomiting, drowsiness, constipation, infection and rash and so on in two groups after treatment, and there was no signiifcant difference between two groups. Conclusion Thalidomide combined with VAD regimen has a better effect in treatment of elderly multiple myeloma than single VAD, has less adverse reactions and well tolerated.
6.Influences of different anesthesia methods or adjuvant chemotherapy on hemorheological parameters in patients with cervical cancer
Liyan KANG ; Haidong WANG ; Qingfeng HU ; Hongming WANG ; Weian XU
The Journal of Clinical Anesthesiology 2014;(7):669-671
Objective To observe the influences of different anesthesia methods or adjuvant chemotherapy on hemorheological parameters in patients with cervical cancer.Methods Sixty pa-tients with cervical cancer were equally randomized into two groups.Patients in group A received three courses of chemotherapy preoperatively while those in group B did not.The patients of group A and B were divided respectively into two subgroups,combined epidural general anesthesia group (groups A1 and B1),general anesthesia group (group A2 and B2).Blood samples were taken for the hemorheological measurement at 5 min before induction of anesthesia,60 min after induction of anes-thesia and at the end of surgery.Results Red cell deformability index (EDI)was significantly lower in group A than that in group B;Erythrocyte rigidity index (ERI)and blood viscosity were higher in group A compared with those in group B (P <0.05).In groups A1 and B1,EDI,plasmic viscosity packed ERI,and ERI were all lower than those before anesthesia induction (P < 0.01 );while in groups A2 and B2 Hct decreased.Conclusion The patients of cervical cancer after chemotherapy showed some hemorheological changes characterized by a lowered EDI.Combined general and epidural anesthesia can significantly improve the above parameters.
7.Identification of the binding region for interaction of optineurin with neural retina leucine
Chunxia, WANG ; Hongming, DONG ; Yu, ZHAO ; Qichang, YAN ; Jinsong, ZHANG
Chinese Journal of Experimental Ophthalmology 2014;32(8):677-681
Background Gene encoding optineurin (OPTN) is a causative gene for glaucoma and amyotrophic lateral sclerosis,with a more expression in retina.Our previous study isolated OPTN-interacting proteins and identified that the gene encode the basic leucine zipper (bZIP) transcription factor neural retina leucine (NRL) zipper,a causative gene for retinitis pigmentosa,and further study demonstrated the interaction between OPTN and NRL proteins in nuclei of cultured HeLaS3 cells.Objective This study was to determine the protein binding site of OPTN necessary for NRL binding.Methods A deletion series of OPTN-expression plasmids were constructed and co-expressed with hemagglutinin (HA)-tagged NRL in HeLaS3 cells,respectively.The cytoplasmic and nuclear fractions were used to perform co-immunoprecipitate (CoIP) and Western blot with anti-tag antibodies.Results In the nuclear fractions of cells transfected with the del1 st,del2nd or del3rd plasmid,a band of coimmunoprecipitated HA-labelled NRL (HA-NRL) was detected.However,the del4th plasmid did not produce a band.The NRL band was not found in cytoplasmic fractions from transfected cells with any of the deletion plasmids or with the whole-length OPTN plasmid.Conclusions The protein binding site of OPTN necessary for NRL binding is determined.This result demonstrates the binding of Flag-OPTN and HA-NRL in HeLaS3 cells.A series of partial-deletion OPTN plasmids demonstrated that the tail region (423-577 amino acids) of OPTN was necessary for binding with NRL.
8.Application of adaptive statistical iterative reconstruction in low dose temporal bone CT scan of children
Bin HE ; Ying GUO ; Ruijing YANG ; Hongming LIU ; Pengcheng WANG
Chinese Journal of Radiological Medicine and Protection 2016;36(7):544-547
Objective To evaluate clinical use of adaptive statistical iterative reconstruction (ASiR) method in low-dose scan on children temporal bone by comparison of radiation dose delivered by GE Discovert HD CT 750 scan and GE Lightspeed VCT64 scan.Method Sixty patients with congenital deafness were divided into two groups according to gender,age (each N =30).Group a received low-dose CT scan on temporal bone by GE Discovery HDCT 750 (preset NI =12),and the original images were reconstructed with ASiR (weighted value =40%).Group B received CT scan by GE Lightspeed VCT 64 (preset NI =8),and the original images were reconstructed with filter back projection (FBP).Data were collected and analysed using the SPSS 18.0 software.Resultes The mean value of electric current of average tube and CTDIvol were significantly different between group A and B [(110.40 ± 21.72) mA vs.(168.56±24.36) mA,and (26.43 ±3.48) mGy vs.(39.66 ±4.17) mGy,respectively (t=-9.76,-3.31,P<0.05)].The noise index was (33.13 ±2.68) in group A and (33.79 ±2.93) in group B respectively,and the results had no statistical significance (P > 0.05).Subjective scores of the images were (4.06 ± 0.03) and (4.05 ± 0.03),with no statistical significance either (P > 0.05).Conclusions On a condition of achieving same image quality,CT scan program using GE Discovery HD CT 750 with 40% ASiR reconstruction and 4 units NI value enhancement could effectively reduce radiation dose on children's temporal bone compared to FBP method using GE Lightspeed VCT 64.
9.Methods and techniques for precise verification of IMRT dose distribution using DVS.
Peihe WANG ; Yong LI ; Hongming LIU ; Jie LIU
Chinese Medical Equipment Journal 1989;0(02):-
Precise verification is required in the execution of intensity-modulated radiotherapy (IMRT) for its complexity. Thereinto, the verification of dose distributions is the emphases and nodus. Some problems in the verification by using radiotherapy planning dose verification system (DVS) are explored such as how to verify the precision and credibility, how to reduce errors in every verification step, how to provide quantified analysis. A suit of practical methods and techniques are summarized from equipment selection to quantified analysis.
10.Application of superselective embolization in the treatment of meningioma
Hao WU ; Chunhong WANG ; Rui CHENG ; Yao WEI ; Hongming JI
Chinese Journal of Primary Medicine and Pharmacy 2015;(16):2450-2452
Objective To investigate the clinical effect of super selective embolization combined with opera-tion for treatment of meningiomas.Methods 82 cases treated by operation and pathology in return for meningioma were collected in the study,including 44 cases of preoperative superselective embolization for aneurysms as the treat-ment group,and the remaining 38 cases without preoperative embolization of patients as the control group.The opera-tion time,bleeding amount in the operation and the rate of total tumor removal were recorded and compared between the two groups.Results The average amount of bleeding of treatment group was (330.36 ±95.41)mL.The average amount of bleeding of control group was (460.82 ±114.64)mL.The data of the two groups was statistically significant (t =5.624,P <0.01).,The treatment group bleeding amount was less than that of the control group;,the mean oper-ation time of treatment group was (5.36 ±2.62)h,,the average operation time of control group was (6.63 ±2.25)h.The data of the two groups was statistically significant (t =2.355,P =0.021 ),the operation time of the treatment group was less than that of the control group.The total resection rate was 70.4% in treatment group and 36.8% in the control group,there was statistically significant (P <0.05),and the total resection rate in the treatment group was higher than that in the control group.Conclusion Compared with single operation treatment of meningiomas superse-lective embolization combined with operation for treatment of meningiomas can shorten operation time,reduce intraoperative hemorrhage,improve the rate of total tumor removal.It can reduce the operation risk and improve the treatment effect.