Objective To observe the efficacy differences and influencing factors of inter-ventional embolisation at different times on patients with intracranial aneurysm (AN).Methods The clinical data of 60 AN patients underwent interventional embolisation in our hospital from Feb. 2010 to Feb.2013 were retrospectively analyzed and divided into early group (26 cases)and post-poned group (34 cases)according to the interventional embolisation at different times.Embolism severity and complications were compared between two groups and the short-term outcomes and rel-evant influencing factors were observed.Results The number of complete embolism was larger in early group than that in postpone group (P <0.05),but there were no significant differences in major and partial embolisms (P > 0 .0 5 ).The total rate of complications in early group was 7.69%,but had no significant difference with the 20.59% in postpone group (P >0.05).43 pa-tients had well short-term outcomes and 17 with bad ones when discharg (P >0.05).Genders, ages and AN diameter had no effect on the short-term outcomes,but the history of hypertension,multiple aneuryson ,Hunt - Hess degrees and the times for interventional embolisation had significant association with the outcomes (P <0.05,P <0.01).Conclusion The interventional embolisation conducted within 3 d after AN onset can evidently improve the rate of complete em-bolism without increasing the rate of complications.Hypertension,multiple aneuryson and Hunt-Hess degrees are the risk factors that influence the outcomes of AN patients.

Objective To observe the efficacy differences and influencing factors of inter-ventional embolisation at different times on patients with intracranial aneurysm (AN).Methods The clinical data of 60 AN patients underwent interventional embolisation in our hospital from Feb. 2010 to Feb.2013 were retrospectively analyzed and divided into early group (26 cases)and post-poned group (34 cases)according to the interventional embolisation at different times.Embolism severity and complications were compared between two groups and the short-term outcomes and rel-evant influencing factors were observed.Results The number of complete embolism was larger in early group than that in postpone group (P <0.05),but there were no significant differences in major and partial embolisms (P > 0 .0 5 ).The total rate of complications in early group was 7.69%,but had no significant difference with the 20.59% in postpone group (P >0.05).43 pa-tients had well short-term outcomes and 17 with bad ones when discharg (P >0.05).Genders, ages and AN diameter had no effect on the short-term outcomes,but the history of hypertension,multiple aneuryson ,Hunt - Hess degrees and the times for interventional embolisation had significant association with the outcomes (P <0.05,P <0.01).Conclusion The interventional embolisation conducted within 3 d after AN onset can evidently improve the rate of complete em-bolism without increasing the rate of complications.Hypertension,multiple aneuryson and Hunt-Hess degrees are the risk factors that influence the outcomes of AN patients.

Objective:To investigate the prevalence of pre-diabetes mellitus (PDM) and the impact of occupation-related factors on PDM, among workers from a steel company in Tangshan city, Hebei province.Methods:Clustering sampling method was used to select a steel company and to carry out occupational health-related physical checkup programs for eligible workers who had working in this company for longer than one year. The study began in February and ended up in June, 2017. Workers who were with FPG level as ≤6.9 mmol/L, and free from diabetes, were selected as the subjects for this study. Questionnaires were used and physical examinations and FPG testing conducted.Results:The total number of subjects in this study was 4 173, of which 2 648 appeared as pre-diabetic, with the prevalence rate as 63.4 %. Increase of the PDM prevalence was in parallel with the length of service, among the workers. The risk for the pre-diabetes in those who worked more than 8 hours per day was 1.696 times higher than those who worked less than or equal to 8 h/d (95 %CI:1.517-1.937). Compared with those workers without exposures to heat, noise or carbon monoxides, the proportion of pre-diabetes appeared higher in workers exposed to heat, noise or CO with OR=1.782 (95 %CI: 1.205-2.636), 1.815 (95 %CI: 1.209-2.794) and 1.653 (95 %CI: 1.158-2.361), respectively. Risks for those who were exposed to heat or noise were higher than those who were free from exposure to any occupational hazards ( OR=2.098, 95 %CI: 1.296-3.397). Prevalence rates of pre-diabetes in those who were exposed to heat, noise or CO, were higher than that those who were not. Conclusion:Working hours and exposures to heat, noise or CO appeared as influential factors on PDM.

OBJECTIVE: To analyze the effect of occupational stress on abnormity of serum total cholesterol and triglyceride in male steel workers. METHODS: A total of 3 957 male steel workers from an iron and steel group company were selected as study objects by judgment sampling method. Occupational stress was measured by the Chinese version of Job Content Questionnaire. The serum total cholesterol and triglyceride levels were measured using fasting venous blood. RESULTS: Among the 3 957 workers,the detection rate of occupational stress was 56. 8%,and 55. 0% of them showed high social support. The abnormal rates of total cholesterol and triglyceride were 21. 8% and 40. 9%,respectively. The multivariate logistic regression analysis showed that workers with high social support had high risk of abnormal total cholesterol and abnormal triglyceride than workers with low social support( P < 0. 05) after adjusting for confounding factors such as age,education level,marital status,body mass index,smoking and drinking alcohol,tea. The odds ratio of abnormal total cholesterol in occupational stress workers was 1. 17 times of that of non-occupational stress workers. No association was found between occupational stress and abnormal triglyceride( P > 0. 05). CONCLUSION: Occupational stress may be associated with abnormity of total cholesterol in male steel workers. Social support is an important influences factor to the abnormity of total cholesterol and triglyceride in male steel workers.

OBJECTIVE: To explore the effects of cumulative noise exposure(CNE) on the intima-media thickness(IMT) of carotid artery in steel workers. METHODS: A cluster random sampling method was used to select 1 437 noise exposed workers in a steel company as study subjects. The CNE was calculated according to the noise intensity of the workplace, and the occupational health check was carried out to construct the structural equation model of noise to IMT. RESULTS: The detection rate of carotid atherosclerosis(CAS) in these 1 437 subjects was 38.3%. The CAS detection rates of steel workers increased with the increasing CNE(P<0.01). The structural equation model had good fitting effect. Path analysis showed CNE can indirectly affect IMT through blood pressure, triglycerides, fasting blood glucose, homocysteine, high-density lipoprotein & apolipoprotein A, low-density lipoprotein & apolipoprotein B. The total effects were-0.375, 0.337, 0.248, 0.117, 0.056, 0.056 and 0.018 respectively. CONCLUSION: CNE can indirectly increase the IMT of steel workers by acting on the proximal cause.

OBJECTIVE: To explore the effect of occupational high temperature exposure on type 2 diabetes( T2 DM) in male steel workers. METHODS: A cluster random sampling method was used to select 684 male steel workers,who exposed to occupational high temperature in a steel enterprise in Tangshan City,as the high temperature group,and 1 153 male steel workers without occupational high temperature exposure as the control group. The high temperature level of workers in these two groups was measured. The cumulative exposure( CE) of high temperature was calculated,and occupational health exam was performed. The multivariate logistic regression analysis and restricted cubic splines were used to analyze the relationship between high temperature CE and T2 DM. RESULTS: The prevalence of T2 DM in high-temperature group was higher than that in the control group( 13. 0% vs 7. 9%,P < 0. 05). The multivariate logistic regression analysis results showed that the risk of T2 DM in the high temperature group was higher than that in the control group after adjusting for age,body mass index,smoking,drinking,physical exercise and parents with diabetes( P < 0. 05). The 95% confidence interval was 1. 65( 1. 17-2. 33). Restricted cubic spline analysis showed that the high temperature CE was correlated with the prevalence of T2 DM in workers( P < 0. 01) and showed a linear correlation( nonlinearity test,P > 0. 05). CONCLUSION: Occupational high temperature exposure is associated with the occurrence of T2 DM in male steel workers. The male steel workers with high temperature CE show high prevalence of T2 DM risk.