Objective To explore the diagnosis value of ilneven inside sign in small hepatocellular carcinoma.Methods Uhrasonography was performed on 100 echogenic areas in livers.to view uneven inside sign in them.And to compare with the clinicopathological characteristics.Results Around all the echogenie areas,there were 90with the uneven inside sign.85 echogenic areas were small hepatocellular carcinoma.There were 10 without the Lineven inside sign.4 echogenic areas were hepatocellular carcinoma.Conclusion The uneven inside sign has high value in diagnosis of small hepatocellular carcinoma.

Mechanical loading plays an important role in stimulating osteogenesis. Increasing mechani-cal loading, via sports and mechanical vibration may increase bone mass and imluce better microstructure, where-as, lack of mechanical loading in the situation like space walking, long bed-ridden, ete, results in bone loss and osteoporosis. Although the mechanism through which mechanical loading stimulates bone formation is not clear, experiments have proved that local mechanism is more important than systematic mechanism. This article aims to review the local mechanism of mechanical loading stimulating osteogenesis.

Objective To investigate the effect of hotistic nursing intervention on negative emotion and quality of life of patients with hypertensive cerebral hemorrhage. Methods One hundred and twelve hypertensive cerebral hemorrhage inpatients with negative emotion disorder from 2006 June to 2008 December were randomly divided into the routine nursing group and the holistie nursing intervention group with 56 patients in each group. The routine nursing group were given the normal nursing care of hypertensive cerebral hemorrhage,the holistic nursing group received psychological nursing, health education and rehabilitative intervention on the basis of normal nursing care for 4 weeks. All patients were evaluated with self rating depression scale (SDS), self rating anxiety scale (SAS) and GQOIL before and after investigation. Results There was no difference in GQOIL, SDS and SAS between the two groups before nursing intervention. After the holistie nursing intervention, the scores of SDS and SAS of the holistic nursing intervention group were significantly lower than that of the routine nursing group, the score of GQOIL was better than that of the routine nursing group. Conclusions The holistie nursing intervention obtains a better effect on managing the hypertensive cerebral hemorrhage patients with negative emotion disorder, it is effective in alleviating negative emotion and raising their quality of life.

Ideas to establish the system for assessing the technical performance of librarians were proposed by using team cooperation model, establishing communication feedback system, keeping abreast of important dynamic informa-tion about scientific projects , enforcing construction of key subjects , characteristic databases and resources , accord-ing to the insufficient librarians and funds, few exchange and training opportunities.The new information service model in small-sized libraries was discussed, including active service, professional service, participation service and innovative service.

Objective To compare the application of National Standard GB/T 20470-2006 and Industry Standard WS/T 403-2012 in quality management of biochemical detection .Methods Comparison of indexes such as σ level ,quality goal index (QGI ) , priority improvement measure and performance evaluation were conducted in projects of external quality assessment launched in this department .Results Differences of performance evaluation showed no statistically significant between National Standard GB /T 20470-2006 and Industry Standard WS/T 403-2012(P= 0 .069) ,while their differences of σ value classification and priority im-provement measure were statistically significant (P were 0 .007 ,0 .012 ,respectively ) .Conclusion Industry Standard WS/T 403-2012 is more stringent than National Standard GB/T 20470-2006 .

Objective To study on the effect of situational teaching based on ECS in medical nursing teaching.Methods 93 nursing students were divided into the experimental group (45 cases) and the control group (48 cases).The experimental group adopted ECS in the medical nursing situational teaching,while the control group used conventional teaching method.The teaching results between the two groups were compared between two groups.Results Two groups had significant differences in the medical nursing theory test and the operation skills examination.The students in the experimental group had higher recognition on the situational teaching based on ECS,especially in the learning initiative and interest,pathology observation ability and the unity cooperation ability,the differences showed statistical difference.Conclusions The application of ECS in the medical nursing situational teaching can stimulate the learning interest of the nursing students,help the cultivation of clinical thinking ability,relieve the contradiction of resources strain in nurses clinical probation and promoting the improvement of medical nursing teaching.

Objective To observe the situation of sexual life of gynecological cancer patients after surgery and explore the pertinent nursing intervention.Methods 400 patients with gynecological cancer and undergoing surgical treatment were selected in our hospital from February 2009 to September 2011.They were divided into the intervention group and the routine group with 200 cases in each group.The sexual psychological change,recovery of sexual life of patients of different types,sex frequency before and after treatment,and satisfaction degree with sexual life after positive nursing intervention were observed using phenomenological analysis.Results The satisfaction degree with sexual life reached 88％ in the intervention group after operation,significantly higher than 52％ in the routine group.Evident psychological changes were seen in patients with younger age,low-level education background,long treatment course and better economic condition.Conclusions Positive nursing intervention and guidance should be given to postoperative gynecological tumor patients in order to help them improve the quality of life and social status.

Objective To observe the curative effects of carboprost tromethamine injection in treatment of postpartum hemorrhage due to uterine inertia.Methods The clinical data of 118 patients with postpartum hemorrhage due to uterine inertia were analyzed retrospectively.The patients were divided into control group (68 cases) and observation group (50 cases) by treatment method.The patients in control group were given conventional treatment while the patients in observation group were given carboprost tromethamine injection on basis of conventional treatment.The postpartum blood loss after 2,24 h after treatment,the third labor time and therapeutic effects in two groups were recorded and compared.The patients in control group took carboprost tromethamine injection if conventional treatment did not work and all patients should have surgery immediately if repeatedly carboprost tromethamine injection were invalid; adverse reactions of using carboprost tromethamine injection were closely watched.Results The postpartum blood loss after 2,24 h after treatment in control group was (676 ± 86),(751 ± 70) ml,which was higher than that in observation group [(238 ± 62),(281 ± 56) ml],and there was significant difference (P ＜ 0.05).The third labor time in control group was (5.1 ± 1.9) h,which was longer than that in observation group [(2.1 ± 1.4) h],and there was significant difference(P＜ 0.05).After conventional treatment with 47 patients stopped bleeding in control group,and the effective rate was 69.1％ (47/58),while the effective rate in observation group was 96.0％ (48/50),and there was significant difference (P ＜ 0.05).Twenty-one patients in control group accepted carboprost tromethamine injection after treatment,while the traditional therapy did not work,and the effective rate increased to be 95.2％ (20/21).Among carboprost tromethamine injection treatment of 71 patients,2 cases' blood pressure increased,2 cases had facial blushing,1 case with mild headache,3 cases of diarrhea and 3 cases of nausea and vomiting (a total of 11 cases),and the incidence rate was 15.5％ (11/71),which was relatively minor.All patients were given symptomatic treatment and all rell eased within 24 h,and there were no other serious adverse reactions.Conclusion Using carboprost tromethamine injection to treat postpartum hemorrhage due to uterine inertia has more remarkable curative effects and higher clinical safety,which is worthy of clinical promotion.

Objective To provide basic datas for enriching the scientific and reasonable security strategy of blood transfusion in Chongqing ,even for the national use in the future ,we studied the infection status of human parvovirus B19(B19V) among unpaid blood donors and evaluated the prevalence of B19V in Chongqing .Methods B19 IgM and B19 IgG antibody from blood donors were detected by the method of enzyme linked immunosorbent assay .Results Among 1 104 blood samples of blood donors ,the positive rate of B19 IgM was 5 .07% ,and the positive rate of B19 IgG was 36 .68% ,there was a significant difference between them(P<0 .05) .The positive rate of B19 IgM from females was higher than males′(P<0 .05) ,but there was no statistical difference for the positive rate of B19 IgG between different gender(P> 0 .05) .Comparing with various age groups ,There was still no significant difference of the positive rate of B19 IgM among them(P>0 .05) ,but the positive rates of B19 IgG increased with age increasing (P<0 .05) .The different blood types or collection seasons ,and the statistical difference were not established in these two condi‐tions (P>0 .05) .And there was no significant difference for positive rate of B19 IgM between positive samples and negative sam‐ples of HBV ,HCV ,HIV ,the results of B19 IgG also were such(P> 0 .05) .Conclusion Among blood donors in Chongqing ,al‐though there was no screening for B19V ,we still found infections by B19V .So this may illustrated that the risk of blood transfusion by B19V was still existed .

Familial mediterranean fever (FMF) is a hereditary inflammatory disorder,which caused by mutations in MEFV gene located on short arm of Chromosome 16 p13.3.The majority of patients onset before the age of 10 years,which is characterized clinically by the episodes of inflammatory reaction and serositis,including fever,peritonitis,synovitis and pleurisy.AA-amyloidosis with kidney failure is the most important complication.The children patients were diagnosed mainly on clinical evaluation and the criteria developed by Yal(c)inkaya.The ultimate goal of treatment in FMF is to obtain complete control of unprovoked attacks and minimise subclinical inflammation in between attacks.The only agent that decreases the frequency and severity of the episodes and the development of amyloidosis is colchicine,which should be startcd as soon as a clinical diagnosis is made,alternative biological treatments such as IL-1 receptor antagonist are indicated in patients with non-responders or resistant to colchicine.