1.New problem and progress of transient tachypnea of the newborn
Chinese Journal of Applied Clinical Pediatrics 2014;29(9):713-715
Transient tachypnea of the newborn (TTN) is the most common cause of respiratory distress.TTN is a self-limiting disease which has a good prognosis but sometimes severe cases may cause pulmonary edema,respiratory distress,pulmonary air leak or persistent pulmonary hypertension.Researchers have many studies about pathogenesis,clinical features,treatment of TTN at home and abroad,and they have new progress.This article will summarize recent research progress on TTN.
2.The design of WPSM with wearable technology
Zhengbo ZHANG ; Mengsun YU ; Hongjin ZHANG
Chinese Medical Equipment Journal 1989;0(03):-
Warfighter physiological status monitor (WPSM) is a new device for noninvasive biomedical measurements for soldier vital signs in operational environments. This paper gives an introduction to the WPSM and analyses the key technologies to design WPSM. The wearable technology can provide a systematic way of monitoring the vital signs of humans in a unobstrusive manner. In this paper the wearable technology is used to design WPSM to fulfill non-instrusive vital signs detection.
3.A radiological anatomy study of the olfactory sulcus and adjacent structures in Chinese
Yiwen YAO ; Lijie ZHAI ; Qing ZHANG ; Shengbo YU ; Hongjin SUI
Chinese Archives of Otolaryngology-Head and Neck Surgery 2007;14(10):614-618
OBJECTIVE An understanding of the complex anatomy of the anterior skull base is crucial for the surgeon doing endoscopic surgery. The anatomic data of the olfactory sulcus and adjacent structures in Chinese patients were defined using 3-dimensional reconstruction images. The surgeon is encouraged to develop a detailed pre-operative surgical plan by utilizing these dynamic anatomical observations to avoid intracranial injury. METHODS The paranasal sinus CT scanning images of 100 adults were reconstructed for observation using EBW2.0 software and multiplanar reformation. All data obtained were in the coronal plane from the anterior point of the olfactory sulcus. The cribriform plate depth as compared to the ethmoid roof and adjacent structures, was measured bilaterally. Data obtained on adjacent structures include the vertical height of the lateral lamella of olfactory sulcus, the horizontal distance between the cribriform plate and the orbital lamella, the length of the middle turbinate, the height of the orbit, and the vertical distance between the cribriform plate and the nasal floor. RESULTS The olfactory sulcus was classified into three types: platform type (60 %), sloping type (17 %) and mixed type(23 %), as distinguished from Keros classification. In this study the vertical height of the lateral lamella of olfactory sulcus was (5.03 ± 0.17) mm (R) and (5.39 ± 0.19) mm (L) in platform type, and (2.79 ± 0.49) mm (R) and (4.72 ± 0.49) mm (L) in the mixed type. There were statistically significant differences between the right side and the left side in these two types (P<0.01). The horizontal distance between the cribriform plate and the orbital lamella on the same side was significantly different between the platform type and the mixed type of olfactory sulcus. A similar result was observed for the vertical distance between the cribriform plate and the nasal floor. Gender differences exist in the horizontal distance between the cribriform plate and orbital lamella on the same side and the vertical distance between the cribriform plate and the nasal floor. CONCLUSION Different types of olfactory sulcus have distinct characteristics, hence care which must be taken into account when doing endoscopic surgery.
4.Clinical Analysis of Aged Coronary Heart Disease Patients with Obstructive Sleep Apnea-Hypopnoea Syndrome
Lei GUO ; Mengsun YU ; Hongjin ZHANG ; Xiaoping HOU ; Jun YANG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(9):880-881
Objective To explore the effect of obstructive sleep apnea-hypopnoea syndrome(OSAHS)on coronary heart disease in the elder.Methods 27 aged coronary heart disease patients were selected and divided into non-OSAHS,OSAHS groups according sleep apnea-hypopnoea index(AHI).Their age,body mass index,the incidence of myocardial infarction,heart failure,arrhythmia were compared.Results There were significantly higher incidences of heart failure,arrhythmia in OSAHS group than in non-OSAHS group,as well as body mass index.Conclusion OSAHS may aggravate the coronary heart disease in elderly patients.
5.A QUANTITATIVE STUDY ON THE SYNAPTIC PLASTICITY IN THE MOLECULAR LAYER OF DENTATE GYRUS OF KAINATE RAT
Hongjin SUI ; Ji GONG ; Shengbo YU ; Huanfa YI ; Dengdong LI ; Wanqin ZHANG
Acta Anatomica Sinica 1989;0(S1):-
Objective In order to investigate the synaptic plasticity in dentate gyrus after seizures and axonal and dendrtic sprout- ing induced by KA administration. Methods The density of synapses, the curvature forms of synaptic interface were studied under electron microscope. Results 1 .The density of the synapse is decreased obviously 3 days after KA injection, while the density of synapses is increased to control level 7 days after KA injection. 2. Compare with the curvation forms of synaptic interface of control animals and 3days after KA administration animals, the amount of smile synapses is significantly decresed and the amount of frown synapses is significantly increased in the moleculous layer of dentate gyrus 7 days after KA injection. Conclusions 1 .This result demonstrates that the axonal and dendritic sprouting of dentate granule cells is functional. 2. The increase of frown synapse is related to the release of glutamate of sprouting mossy fibers.
6.Analysis on pulse diagram characteristics of subjects with subhealth state.
Guixiang CHU ; Qingguang CHEN ; Jiatuo XU ; Bo YU ; Min ZHANG ; Longtao CUI ; Hongjin WU ; Zhaofu FEI
Journal of Integrative Medicine 2012;10(10):1099-105
To study the pulse diagram parameters of subjects with subhealth state and to find the pulse parameters for subhealth state evaluation.
7.Establishment of orthotopic model of human colon cancer marked by green fluorescent protein and its biological characteristics
Bolin YANG ; Hongjin CHEN ; Yunfei GU ; Yugen CHEN ; Qiu LIN ; Xueliang SUN ; Yu SUN
Chinese Journal of Digestive Surgery 2013;12(8):626-628
Objective To establish a stable orthotopic model with high green fluorescent protein (GFP) expression in nude mice and observe its biological features.Methods Human HCT116 colon cancer cells transfected with GFP pLPCX retroviral plasmid were used to build a subcutaneous tumor model in nude mice.Fifteen BALB/C nude mice were selected to underwent orthotopic transplantation of colon when the GFP-labeled tumor grew to 10 mm × 10 mm as observed by in vivo fluorescent microscopy.The growth and metastasis of orthotopically implanted colon cancer cells were observed with fluorescent imaging system at different time points.The differences of the tumor size measured by peripheral vernier caliper and fluorescent imaging system were analyzed using the t test,and the differences in different groups were analyzed using the analysis of variance.Results GFP-labeled colon cancer models were successfully established in all the 15 nude mice,and there was no surgery-related complications or death.Tumors marked by GFP were observed under fluoroscope in week 3.The size of the tumors progressively increased with time.The volumes of the orthotopically transplanted tumors obtained from global measurement using fluorescent imaging system were greater than those measured by peripheral vernier calipers at postoperative week 3,4,5,6,7,while no statistically significant difference was observed (t =-1.280,-1.115,-0.718,-0.199,-0.386,P >0.05).There was a significant difference in the interation of measure method and different time points (F =29.546,P < 0.05).Eight nude mice survived at the end of the experiment,and tumor metastasis was observed in 6 mice.Conclusions It is technically feasible to construct GFP-labeled colon cancer orthotopic transplantation model.The mice model could be used for real-time,in vivo,non-invasive and dynamic observation and analysis of the growth and metastasis of tumor cells.
8.Extraction of sleep structure information from heart rate variability based on spectrum analysis.
Feng WU ; Mengsun YU ; Qiming CHENG ; Zhangrui JIN ; Hongjin ZHANG
Journal of Biomedical Engineering 2004;21(2):212-214
In this study we made full use of the heart rate spectrum analysis to obtain the character parameters of heart rate variability related to EEG sleep phase information, and then we discarded the correlation between characteristics by employing Principal Component Analysis. Finally, by means of the decision tree based on Fisher rules, we established two full automatic models for identifying healthy people and sleep apnea hypopnea syndroma (SAHS) patients respectively. The result of experiments indicates that the model is accurate and robust.
Decision Trees
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Electrocardiography
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Electroencephalography
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Female
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Heart Rate
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physiology
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Humans
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Male
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Models, Biological
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Polysomnography
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Signal Processing, Computer-Assisted
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Sleep
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physiology
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Sleep Apnea Syndromes
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physiopathology
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Sleep Stages
9.Posttransplant Lymphoproliferative Disorder without Epstein-Barr Virus Presented as Small Bowel Perforation in Renal Transplant Recipient: A Case Report.
Min Jhi KIM ; Hongjin SHIM ; Ji Young JANG ; Su Hyung LEE ; Kyu Ha HUH ; Yu Seun KIM ; Jae Gil LEE
The Journal of the Korean Society for Transplantation 2013;27(3):138-142
Posttransplant lymphoproliferative disorder (PTLD) is documented as one of the serious complications leading to mortality particularly in organ transplant recipients receiving immunosuppressive therapy. Extant literature confirms beyond doubt that the most common site of involvement of PTLD is lymph nodes, and rarely involved is the gastrointestinal tract. It is a well-known fact that Epstein-Barr virus (EBV) is a risk factor for PTLD development. In this study, we report a case of PTLD presented as small bowel perforation without EBV infection after long-term immunosuppressive therapy in a renal transplant recipient.
Epstein-Barr Virus Infections
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Gastrointestinal Tract
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Herpesvirus 4, Human
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Kidney Transplantation
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Lymph Nodes
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Lymphoproliferative Disorders
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Risk Factors
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Transplants