1.Observation of the effect of stripping corpus luteum in the conservative laparoscopic surgery for fallopian pregnancy on prevention of persistent ectopic pregnancy
Honggui ZHOU ; Yuhua ZENG ; Jiaping LI
Clinical Medicine of China 2010;26(1):95-97
Objective To understand the clinical effect of conservative lapamscopic surgery with stripping corpus luteum for fallopian pregnancy to prevent persistent ectopic pregnancy.Methods From January 2005 to Augnst 2008.82 cases of fallopian pregnancy (6 cases for the second time) were performed conservative operatio through laparoscopic surgery with stripping corpus luteum.Seventy one cases underwent salpingostomy to remove the embryo, and other 11 cases were performed with extrusion of embryo sac at ampulla.The level of serum progesterone,β-HCG were measured before and after the therapy.All patients were followed up for one year.Results All patients'surgery had been successfully done through laparoscopie surgery.The duration of stripping corpus luteum was 5 to 10 minutes.The serum β-HCG(Mean±SD:(1213.51±118.84)U/L)and progesterone(Mean±SD:(3.25±2.44)nmol/L)arer operation were significantly lower than before the therapy(Mean±SD:(4267.86±983-56)U/L.(13.71±6.24)nmol/L,respectively)(P<0.01).The decrease of β-HCG value wag significantly correlated with the decreasing of progesterone(r=0.697,P<0.05).Only one patient had a persistent ectopic pregnancy.Fallopian examination through hysterosalpingography after 3 months was unobstructed in 71.1%(32/45 cases)and oh-strueted in 7 cases(15.6%).After one year ofthetherapytwo patients hadectopic pregnancy atthe same fallopian tube.Conclusions For females who have reproductive requirements with experience of fallopian pregnancy,conservative operation through laparoscopic surgery with stripping corpus luteum is safe and effective,and might have an important clinical effect to prevent postoperative persistent ectopic pregnancy.
2.Application of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound in the diagnosis of uterine space-occupying lesion
Dan LIU ; Honggui ZHOU ; Mingxing LI ; Yu ZHANG ; Liqing PENG
Journal of Shanghai Jiaotong University(Medical Science) 2017;37(7):969-972
Objective·To evaluate the clinical value of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound in the diagnosis of uterine space-occupying lesion.Methods·A total of 75 patients with uterine space-occupying lesion were enrolled in this study from March 2015 to February 2016 at Hospital of Southwest Medical University.Patients received both two-dimensional ultrasound and four-dimensional color Doppler ultrasound to determine the location,number and nature of the lesions,as well as the clinical staging of malignant lesions,then the diagnostic accuracy was evaluated.Results·Among 75 patients,there were 26 cases with endometrial carcinoma,21 cases with hysteromyoma,16 cases with metropolypus,and 12 cases with uterine adenomyosis.The diagnostic accuracy of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound for the uterine space-occupying lesion was 88.0%,which was significantly higher than that of two-dimensional ultrasound (64.0%) (P<0.05).What's more,the diagnostic accuracy of two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound for the clinical staging of endometrial carcinoma was 88.5%,which was significantly higher than that of two-dimensional ultrasound (61.5%) (P<0.05).Conclusion·Two-dimensional ultrasound combined with four-dimensional color Doppler ultrasound is more effective to improve the diagnostic accuracy of uterine space occupying lesion and clinical staging of endometrial carcinoma in comparison with two-dimensional ultrasound,which will favor the clinical strategy for the treatment of uterine space-occupying lesion.
3.Unexpected discovery of cervical cancer:one case report and literature review
Zhenjun WANG ; Honggui ZHOU ; Miao ZHANG ; Jun LIU
Practical Oncology Journal 2016;30(5):441-443
The unexpected discovery of cervical cancer ( UDCC) rarely occurs in clinics .Because it is di-agnosed by pathology after surgery ,the therapies are different from ordinary cervical cancer .In addition,the choice of the timing of surgery and other issues are also involved .The patient received the hysterectomy due to cervical intraepithelial neoplasia III and uterine fibroids .Postoperative pathology examination showed cervical microinva-sive carcinoma,stage IA1,and pathology without lymph -vessel invasion involvement ,the patient needs to be fol-lowed up closely postopertation .One case of the unexpected discovery of cervical cancer was reported in this pa -per.The aim is to provide a reference for clinical management .
4.Hemorrhagic cystitis in children undergoing hematopoietic stem cell transplantation Clinical characteristics and risk factors
Honggui XU ; Jianpei FANG ; Shaoliang HUANG ; Dunhua ZHOU ; Chun CHEN ; Ke HUANG ; Yang LI
Chinese Journal of Tissue Engineering Research 2008;12(8):1596-1600
BACKGROUND: Hemorrhagic cystitis (HC) is one of common complications in patients undergoing hematopoietic stem cell transplantation (HSCT). It is of great value for improvement in the HSCT outcome to describe the clinical characteristics of HC and risk factors. OBJECTIVE: To investigate the incidence of HC in children after HSCT, and to analyze its clinical characteristics and risk factors.DESIGN: Case analysis SETTING: Center of Hematopoietic Stem Cell Transplantation, Department of Pediatrics, Second Affiliated Hospital of Sun Yat-sen University.PARTICIPANTS: Experiments were performed at the Center of Hematopoietic Stem Cell Transplantation, Department of Pediatrics of Second Affiliated Hospital of Sun Yat-sen University from October 1998 to June 2004. Eighty-eight patients receiving umbilical cord blood transplantation (UCBT) and peripheral blood stem cell transplantation (PBSCT) were enrolled; 49 were males and 39 were females. The age ranged from 2 to 18 years with an average of 8.0 years. Guardians of child patients signed informed consents. The experimental procedures were approved by Medical Ethics Committee.METHODS: ①Conditioning regimens included combination of cyclophosphamide (CY, 120-200 mg/kg) with busulphan (BU, 14-20 mg/kg)-based chemotherapy and combination of CY with total body irradiation (TBI, 2-8 Gy) or total lymphoid irradiation (TLI, 2-8 Gy)-based radiotherapy. ②HC was defined according to the criteria proposed by references 7 and 8. The incidence, clinical characteristics, laboratory examination, treatment and outcome for HC were described. The association of various clinical factors including age, gender, human leucocyte antigen (HLA) typing, diseases for transplant, the type of stem cell, the type of transplantation, the occurrence of acute graft-versus-host disease (aGVHD) and cytomegalovirus (CMV) infection with the development of HC were examined.MAIN OUTCOME MEASURES: ①Incidence of HC, ②HC patient characteristics and laboratory examination, ③HC treatment and outcome, and ④risk factors analysis. RESULTS: All 88 patients were included in the final analysis. ①The incidence of HC: 16 patients (18.2%, 16/88) developed HC post-transplant with the severity graded as mild in 11 cases (68.7%) and severe in 5 cases (31.3%). ②HC patient characteristics and laboratory examination: All had hematuria and 8 cases (50.0%) had typical pollakisuria, urinary urgency, odynuria and gross hematuria; 10 cases (62.5%) had gross hematuria and 11 had proteinuria (+ to +++); Leucocytes were detected in 7 cases. ③Treatment and outcome: All patients recovered at a median of 13.5 days (range 2-53 days). ④Risk factors analysis: The incidence of HC was significantly higher in the group of ≥ 6 years old, presence of aGVHD and development of cytomegalo-virus (CMV) infection (P < 0.05-0.01). CONCLUSION: ①HC has its own clinical characteristics following HSCT in children but with good prognosis. ②The risk factors for HC are ≥ 6 years old, presence of aGVHD and CMV infection.
5.Reliability and validity of Chinese revision of rumination on sadness scale in undergraduates
Huiqin LIU ; Xilin WU ; Yanqi LIANG ; Honggui ZHOU ; Dongfang WANG ; Yunlong DENG
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(12):1133-1137
Objective To revise rumination on sadness scale (RSS) and evaluate the reliability and validity of the Chinese version rumination on sadness scale (RSS-C) in Chinese undergraduates.Methods A total of 1 166 undergraduates from 4 universities in Hunan province completed RSS,ruminative response scale (RRS) and Beck depression inventory-Ⅱ (BDI-Ⅱ).The test-retest was conducted in 111 participants 2 weeks later.Results Item analysis and exploratory factor analysis showed the RSS-C included 11 items,consisting of causal analysis,understanding oneself and one's sadness and uncontrollability of ruminative thinking factors.The scores of each item in the high score group were significantly higher than those in the low group(P<0.001),and the correlation between each item and the total score was significant(r=0.594-0.719,P<0.001).The confirmatory factor analysis indicated good fit(x2/df=3.938,GFI =0.957,NFI =0.940,CFI =0.954,TLI =0.930,IFI =0.954,RMSEA =0.070).The internal consistency for RSS-C and three factors ranged from 0.694 to 0.868,and the test-retest reliability ranged from 0.620 to 0.833.The scores on RSS-C and three factors were significantly associated with RRS(r=0.555-0.637,P<0.01),BDI-Ⅱ (r=0.211-0.403,P<0.01) respectively.Conclusion RSS-C has good reliability and validity and can be used as an effective instrument to assess rumination on sadness in Chinese undergraduates.
6.Reliability and validity of the Chinese version of philadelphia mindfulness scale in college students
Yanqi LIANG ; Huiqin LIU ; Honggui ZHOU ; Dongfang WANG ; Yunlong DENG
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(9):843-847
Objective To explore the reliability and validity of the preliminary revision of the Philadelphia Mindfulness Scale (PHLMS) in Chinese undergraduates.Methods Considering the differences in the cultural and linguistic,the PHLMS was translated and used to conduct a questionnaire survey among 1 221 undergraduates.All participants were also surveyed with five facets mindfulness questionnaire (FFMQ),the white bear suppression inventory (WBSI) and acceptance and action questionnaire-2rd edition (AAQ-Ⅱ) as conduct reliability and validity test.Results The exploratory factor analysis showed that PHLMS could extract two factors,and the cumulative variance contribution rate was 40.355%.The confirmatory factor analysis indicated good fit (x2/df=2.781,CFI =0.945,NFI =0.884,IFI =0.922,TLI =0.906,CFI =0.922,RMSEA =0.053).The internal consistency reliability of the awareness subscales was 0.785,and the internal consistency reliability of the acceptance subscales was 0.772.The correlation coefficients among the PHLMS and FFMQ was significant(r=0.398,P<0.01).The acceptance subscales were significantly negatively correlated with WBSI and AAQ-Ⅱ(r=-0.458,-0.288,P<0.01).Conclusion The validity and reliability of the Chinese version of PHLMS meet the measurement criterion.
7.The mediating role of experiential avoidance and thought suppression between trait mindfulness and rumination in undergraduates
Honggui ZHOU ; Hong LIU ; Lifeng WANG ; Xin MA ; Rui LI ; Yunlong DENG
Chinese Journal of Behavioral Medicine and Brain Science 2019;28(5):448-452
Objective To investigate the relationship between trait mindfulness( TM) and rumina-tion,as well as the mediating effects of experiential avoidance(EA) and thought suppression(TS) in under-graduates. Methods A sample of 1 219 undergraduates was recruited to complete Mindful Attention Aware-ness Scale,Acceptance and Action Questionnaire-Ⅱ,the White Bear Suppression Inventory and Rumination Response Style Questionnaire. Results (1) The significant positive correlations of each two different fac-tors were found among experiential avoidance (18. 020±7. 446),thought suppression (47. 769±10. 011) and rumination (47. 668±10. 497),and the correlation coefficients were 0. 466,0. 546 and 0. 525 respectively, all P<0. 01. TM (64. 977± 9. 623) was found to be significantly related with EA ( r=-0. 450),TS ( r=-0. 424) and rumination (r=-0. 527),all P<0. 01. (2) Partially mediating effect of EA ( effect value=-0. 132) and TS (effect value=-0. 073) were both found in TM and rumination,and the proportion of these two effects were 25. 0% and 13. 9%,respectively. The chain mediating effect of EA and TS (effect value=-0. 042 ) was also found between TM and rumination, whose indirect effect size was 8. 0%. Conclusion The relationship between TM and rumination in undergraduates can be mediated by EA and TS respectively,as well as their chain effect.
8.Establishment of the theory and operation of willing acceptance and commitment therapy.
Journal of Central South University(Medical Sciences) 2018;43(11):1257-1262
Mindfulness-based psychotherapy, known as the third-wave cognitive behavior therapy, showed a multi-cultural integration trend. As part of it, willing acceptance and commitment therapy not only took root in the discoveries in the fields of evolutionary psychology and cognitive psychology, but also absorbed the concepts of psychotherapy from Chinese traditional culture. As a result, it regards truth and harmony as the essence of health, proposes a triangle model (health/pain-willing acceptance-striving) to elucidate the mechanism of psychopathology and psychotherapy in theory. Operationally, it contains four principles of psychotherapy, which are as follow: "knowing yourself and others, reaction but adequately, reality as well as harmony, willing acceptance and striving". Furthermore, it proposes eight therapeutic procedures including "understand yourself, recognize suffering, check coping style, keep openness and acceptance, mindfulness and flexibility, live in the moment, clarify the value, and commit action". With these principles and procedures, willing acceptance and commitment therapy aims to fade the neural trace of patients' painful memories, improve their psychological flexibility and rebuild their lifestyles consistent with their values.
Acceptance and Commitment Therapy
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Adaptation, Psychological
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Cognitive Behavioral Therapy
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Humans
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Mindfulness
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Stress, Psychological
9.Characteristic of SCL-90 in detoxification addicts in reeducation center
Feng LI ; Huan-guang HUANG ; Yue-han SONG ; Pengcheng ZHOU ; Hehe WEI ; Honggui PAN ; Leilei ZANG ; Jing GUAN ; Jia WANG ; Yongkang TAN ; Zhenhe TIAN ; Xiaolan LIU ; Jianxiong HUANG ; Suyuan XIAO ; Yuan LIANG ; Xue LI
Chinese Journal of Rehabilitation Theory and Practice 2006;12(1):73-74
ObjectiveTo investigate the Character of Symptom Checklist 90 (SCL-90) in detoxification addicts in reeducation center.Methods100 detoxification addicts in reeducation center were evaluated.ResultsThe results showed that the mean scores of all factors in detoxification addicts were higher than those of normal population, and there was difference between different drug dependence addicts.ConclusionThe detoxification addicts shows serious psychological disorders.
10.Effect of Synthesized Rehabilitation on Detoxification Addicts
Feng LI ; Huan-guang HUANG ; Lei-lei ZANG ; Pengcheng ZHOU ; Hehe WEI ; Yuehan SONG ; Jing GUAN ; Jia WANG ; Honggui PAN ; Yongkang QIN ; Zhenhe TIAN ; Suyuan XIAO ; Ping ZHANG ; Xiaolan LIU ; Jianxiong HUANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):347-348
ObjectiveTo explore the effect of synthesized rehabilitation on detoxification addicts.Methods100 detoxification addicts were randomly divided into the rehabilitation group and control group with 50 cases in each group. Cases of the rehabilitation group were treated with "ten-step" rehabilitation treatment, but that of the control group did not. The rehabilitating treatment included cognitive psychotherapy, behavioral therapy, family treatment, social skill training and etc. The effects of two groups were evaluate with Symptom Checklist-90 (SCL-90) scale.ResultsExcept hostility, other factorial scores of the rehabilitation group including positive items, somatization, obsession, interpersonal sensitivity, depression, phobia, paranoid and psychotic factors were significantly higher than that of the control group (P<0.05~0.01).ConclusionThe synthesized rehabilitation can obviously improve the psychology of detoxification addicts.