Objective To investigate the X-ray characteristics and differential points of intra-thoracic malignant lymphoma-Hodgkin’s disease(HD) and Non-Hodgkin’s lymphoma(NHL).Methods The X-ray manifestations of intra-thoracic malignant lymphoma in 66 cases(including HD in 20 and NHL in 46) with complete clinical informations and pathologic results were retrospectively analysed.The lymphadenopathy of the hilar and mediastinum,the changes of the intra-lung and pleura were mainly observed and compared with the pathological results.Try to find the characteristic X-ray appearance of the HD and NHL.Results (1)48 cases had enlargement of lymph nodes of the hilar with/or mediastinum,and common seen in NHL,and the lymphopathy appeared as unilateral or asymmetry in NHL,bilateral or symmetry in HD.(2)The involvement of lymph nodes was mostly the anterior mediastinum and retrosternal in HD,the posterior mediastinum in NHL and to cause the paraspinal line widening.(3)Intra-pulmonary lesions always were interstitial changes and common seen in NHL,and seldom seen in HD.(4)NHL was often accompanied with pleural lesions,and HD not.Conclusion Both HD and NHL have its own X-ray characteristics .Carefully observing and analyzing these characteristics are helpful in diagnosing and differentiating HD and NHL.

Objective To observe the mRNA expressions of endothelin-1(ET-1) and endothelin A/B receptors (ETA/B) in tissue of benign prostatic hyperplasia treated by daily low-dose sildenafil.Methods A total of 32 patients with benign prostatic hyperplasia were randomly divided into two groups:treatment(25 mg sildenafi for 12 weeks,n=16) and control (no drug,n=16) groups.Immunohistochemical staining,ELISA and RT-PCR were used to detect the expression levels of ET-1 protein and ET A/B mRNA,respectively.Results The expressions of ET-1 protein and ET A/B mRNA in prostatic tissue were significantly lower in treatment group than in control group[(53.31±18.56) ng/kg vs.(83.34±31.38) ng/kg,0.356±0.056 vs.0.624±0.083,0.721±0.083 vs.0.933±0.905,t=-3.295,10.715,6.937,all P＜0.001].Conclusions Daily low-dose sildenafil can reduce the expressions of ET-1 and ET A/B receptors mRNA in benign prostatic hyperplasia.

Objective To evaluate the clinical application of CT virtual cystoscopy (CTVC). Me-thods Thirteen patients who had clinical indication were studied. Iodine contrast was intravenously injected after the bladder was voided. Thin-slice spiral CT scanning of the bladder area was started when the bladder became filled with contrast media. By using 3D navigator smooth software, CTVC images were obtained. The findings in all cases were compared with the cystoscopy and surgical results. Results Nine patients with CTVC were proved vesical tumor,3 patients with CTVC were proved benign prostatic hyperplasia, and they were confirmed by cystoscopy,1 patient with cystitis glandularis could not be diagnosed with CTVC.By CTVC, the diagnostic accordance rate was 92.3%,the coincidence rate was 100.0% in vesical tumor. Conclusions CTVC is highly sensitive in displaying the vesical lesions.Being a new and non-invasive technique, CTVC is very helpful in the diagnosis of introvesical diseases. It has fine value in the clinical practice.