Objective:To analyze the intestinal preparation effect of dimethicone oil combined with polyethylene glycol electrolyte powder in painless gastrointestinal endoscopy.Methods:The study included 380 patients undergoing painless gastrointestinal endoscopy in Nanjing Qixia District Hospital from January 2020 to June 2021. They were randomly grouped into observation group and control group, with 190 patients in each group. The control group was given polyethylene glycol electrolyte powder + 0.9% sodium chloride for intestinal preparation before gastrointestinal endoscopy, and the observation group was given polyethylene glycol electrolyte powder + dimethicone silicone oil. The intestinal cleanliness, antifoam effect, colonoscopy index, detection rate of polyps, adenomas and advanced adenomas, and adverse drug reactions were compared between the two groups.Results:The satisfaction rates of intestinal cleaning and defoaming in the observation group were 92.11% (175/190) and 90.53% (172/190) respectively, which were obviously higher than those in the control group: 84.71% (161/190) and 83.16% (158/190) ( P>0.05). The entering time of colonoscopy and the time of colonoscopy inspection in the observation group were obviously shorter than those in the control group: (3.35 ± 1.05) min vs. (6.02 ± 1.68) min, (11.86 ± 1.93) min vs. (15.22 ± 2.10) min. The rinsing amount of 0.9% sodium chloride was obviously reduced: (35.68 ± 7.64) ml vs. (50.34 ± 10.30) ml ( P<0.05). The detection rate of <5 mm polyps in the observation group was obviously higher than that in the control group: 15.79% (30/190) vs. 5.79% (11/190) ( P<0.05). The detection rate of adenomas in the observation group was obviously higher than that in the control group: 24.74% (47/190) vs. 15.79% (30/190) ( P<0.05). The detection rate of advanced adenomas in the observation group was obviously higher than that in the control group: 20.53% (39/190) vs. 9.47% (18/190) ( P<0.05). The total incidences of abdominal distension and adverse reactions in the observation group were obviously lower than those in the control group: 1.05% (2/190) vs. 5.26% (10/190), 9.47% (18/190) vs. 18.42% (35/190) ( P<0.05). Conclusions:The application of polyethylene glycol electrolyte powder combined with dimethicone oil in painless gastrointestinal endoscopy can effectively improve the intestinal cleanliness, the satisfaction of removing bubbles and the detection rate of polyps and adenomas, reduce the incidence of adverse reactions, and have high clinical application value.

Objective To explore the status quo of treatment adherence and its influencing factors in community management of patients with chronic diseases in Nanjing. Methods A total of 673 patients with chronic diseases managed by community health service centers in Nanjing were selected. The general data of the study subjects were collected. MMAS-8 Scale, the Chinese version of WHQOL-BREF and PSS-Fa were used to evaluate the treatment adherence, quality of life and family support level. Pearson correlation was used to analyze the correlation between MMAS-8 score and WHQOL-BREF Chinese version and PSS-Fa score, and logistic regression analysis was used to investigate the influencing factors of treatment adherence. Results The MMAS-8 score was positively correlated with WHQOL-BREF Chinese version psychological and social management domain score and PSS-Fa score , logistic regression analysis results suggested that > 65 years of age (OR =1.723) was a risk factor for poor treatment adherence, undergraduate and above education level (OR = 0.582), annual family income > 80 000 yuan (OR = 0.603), comorbidity of chronic diseases (OR = 0.718), better overall evaluation of their own quality of life (OR = 0.547) , and high family support level (OR = 0.619) were protective factors for poor treatment adherence, and the above differences were statistically significant (P < 0.05) . Conclusion There is still room to improve the treatment adherence of patients with chronic diseases in community management in Nanjing . It is necessary to focus on elderly patients, strengthen the education of patients with single chronic diseases and improve the quality of life and family support level of patients.