In this paper, the traditional fault tree analysis method is presented, detailed instructions for its application characteristics in medical instrument maintenance is made. It is made significant changes when the traditional fault tree analysis method is introduced into the medical instrument maintenance: gave up the logic symbolic, logic analysis and calculation, gave up its complicated programs, and only keep its image and practical fault tree diagram, and the fault tree diagram there are also differences: the fault tree is no longer a logical tree but the thinking tree in troubleshooting, the definition of the fault tree's nodes is different, the composition of the fault tree's branches is also different.
Algorithms ; Durable Medical Equipment ; standards ; Maintenance

Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclusive method which are the three important methods in the medical equipment maintenance, through using these three methods for the instruments that have circuit drawings, hardware breakdown maintenance can be done easily. And this paper introduces the processing methods of some special fault conditions, in order to reduce little detours in meeting the same problems. Learning is very important for stuff just engaged in this area.
Equipment and Supplies, Hospital ; standards ; Maintenance ; methods ; Safety

Objective: To improve the method of the international popular traditional CBM, and apply it to medical equipment maintenance. Methods: The monitor equipment real-time monitoring was replace by operating personnel’s real-time monitoring and by engineering technical personnel’s professional inspection regularly. The engineering and technical personnel replace experience with data, regularly test data with continuous data, and experience and reasoning of fuzzy with data processing and calculation of the precise results when analyzing the monitoring equipment unit, so as to achieve the purpose of CBM. Results:Compared with the PM mode, CBM mode’s maintenance workload and downtime maintenance reduce more than 30%and maintenance funds spending save 20~30%. Relative to BM mode, the quality success rate of medical instrument improves more than 5 percent and the personal safety hidden danger has fallen sharply. The medical benefit and economic benefit have been improved. Conclusion:It is effective and feasible to introduce the CBM mode to medical equipment maintenance.

Objective:To complete the medical equipment''s quality control on the premise of the lack of professional testing equipment.Methods: According to the working principle of instrument, to come up with corresponding simple and effective way to carry on the daily quality inspection, and make a qualitative conclusion that whether the instrument is qualified.Results:Effectively to ensure the safety and quality of medical equipment, medical equipment each year the average measurement test pass rate above 95% (bureau of quality and technical supervision measurement test results per year); perfectness ratio is around 98%.Conclusion: In the case of lack of professional testing equipment, through the integrated use of various effective means, can do the qualitative check that whether the performance of all sorts of equipment is qualified , achieve the goal of quality control.

Gansu province is a high incidence area of gastric cancer,and the mortality caused by gastric cancer ranks first in China.A safe and effective treatment of gastric cancer is the key point in the research.In recent years,tumor-targeted therapy has become a new research direction along with the gradually increased understanding of the molecular biology of cancer mechanism.Several studies have shown that increased expression of cyclooxygenase (COX)-2 plays an important role in the occurrence and development of malignant tumor.Celecoxib,a non-steroidal anti-inflammatory drug,is a novel COX-2 selective inhibitor which can significantly reduce the incidence of gastrointestinal malignancy,and inhibit tumorigenesis through inhibiting tumor growth and tumor angiogenesis,inducing the apoptosis of tumor cells,reversing multidrug resistance,enhancing the cytotoxicity and radiosensitivity of chemotherapy drugs,and producing synergistic effects with combining chemotherapy and radiotherapy.Therefore,celecoxib has the potential to be the treatment of choice for gastric cancer.

To capture a state of the enzyme in complex with an intact substrate, we developed and adopted a novel freezing method in crystal preparation procedure. Neither the elimination of the catalytically indispensable ligands, nor mutation or modification of the active site is required. At -20 degrees C, we soaked the crystal of 6-phosphate-beta-glucosidase (Bg1A) in the liquor containing p-nitrophenyl-beta-D-glucopyranoside-6-phosphate (pNPbetaG6P). The diffraction data at 2 A resolution was collected and an intact and unambiguous electron density map of pNPbetaG6P was obtained. These results provide an effective method for the research of cryoenzymology and the intermediate state of enzyme-substrate complex in the future.
Cold Temperature ; Crystallization ; Glucosidases ; chemistry ; metabolism ; Substrate Specificity ; X-Ray Diffraction

Literatures about patella fracture fixation in recent years are analyzed retrospectively in this paper.Its characteristics and therapeutic purpose are investigated.A series of new type of internal fixations and external fixations are emphasized.

Objective To analyze the reason of necrosis for pedunculated skin flaps repaired after floor of the mouth defect repair.Methods 56 cases of pedunclated-flaps restoring the floor of the mouth from 1996 to 2001 were reviewed, and pedunclated-flap repair was performed after operation in 11 cases suffering from malignant tumors in the floor of the mouth, and 5 kinds of pedunculated flaps were compared.Results Five kinds of pedunculated flaps were used to reconstruct the floor of the mouth defects. Its successful sequence was as following: forehead flap, pectoralis major myocutaneous flap, sternocleidomastoid flaps,trapezius myocutaneous flaps, and subhyoid flap.Conclusions Causes of those flaps necrosis might relate to furnishing blood with supplied-flaps region and structure of anatomy in received-flaps region, also it is related to operater's skill.So the reason of repair failure of skin flaps with pedicle needs comprehensive analysis.

Objective To investigate the role of hepatic Kupffer cells in acute hemorrhagic necrotizing pancreatitis associated lung injury(AHNP LI) and the therapeutic effects of gadolinium chloride(GdcI_3). Methods Forty-two Wistar rats were randomly divided into four groups:(I) sham operation group;(II) AHNP group;(III) Gdcl_3 (protection) group(Gdcl3 10mg/kg);(IV) Gdcl_3control group(Gdcl_3 10mg/kg).In the sham operation group, the (abdominal) vescera were shifted around for several times and the abdomen was closed.The AHNP model was induced by retrograde intraductal administration of 5% sodium taurcholate(1ml/kg,0.1ml/min).In the Gdcl_3 protection group,Gdcl_3 solution was admmistered by caudal vein injection one day before the AHNP model was made.In these 3 group of animals,specimens were obtained in order at 3h and 6h postoperatively:(1)Blood was withdrawn from the abdominal aorta to determine serum amylase,TNF?,IL-1(in addition,in the sham operation group,blood AST and ALT were determined);(2)A portion of liguefied right lung was obtained to determine MPO;another portion was fixed with 10% formalin for tissue pathological examination;(3)Bronchoalveolar lavage fluid of excised left lung was obtained ,and then alveolar macrophages were isolated,collected and purified.After removal of their nuclear (proteins),the alveolar macrophages were tested to determine NF-?B activation with the use of chemical illumination ELISA method;and (4)pancreatic tissue was reserved for pathological examination.In the Gdcl_3 control group, Gdcl_3 was administered by caudal vein injection,the animals were sacrificed 24h later,and blood was obtained to determine blood AST and ALT. Results In the Gdcl_3 prevention group,the level of MPO in lung tissue,serum (levels) of TNP? and IL-1,and NF-?B activation of alveolar (macrophages) were all significanfly reduced as compared with the AHNP model group(in all,P

ve To improve the method of determination of aluminium in water. Methods The method of aluminium chrome azurol S-cetylpyridinium bromide spectrophotometry was used. Results The improved determi-nation of aluminium revealed perfect linear relationship in determining the standard aluminium solution series at the range of 0. 0-6.0?g/25 ml aluminium. The regression equation was calculated as y = 1. 031x + 0. 008(r=0.9994) . The detection limit was 0.02 mg/L aluminium. The coefficient variation was below 4.90% . The recovery rate ranged from 93.3% to 100.0% . Conclusion The improved method was rapid and easy to operate, suitable for determination of Al3+ in a large number of water samples.