1.Optimization of the Extraction Process of Qianliening Granules by Orthogonal Test
Wei XU ; Jianheng ZHOU ; Zhenfeng HONG
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective]To filter and optimize extractive technology of Qianliening granules.[Methods]The optimization extractive technology of Qianliening granules was investigated using orthogonal design with the availability component extracting from the drug as the index.[Results]The optimal condition for the extraction of Radix Astragali group was 10 folds amount of water,3 times,1.5 hours each time.The optimal condition for the extraction of Rheum officinal Baill.group was 6 folds amount of 60% alcohol,2 times,two hours and 1.5 hours each time.[Conclusion]The optimized extractive technology is scientific and efficient.
3.Clinicopathological characteristics of clear cell type meningioma.
Xiao LI ; Ru-jun XU ; Hong ZHOU
Chinese Journal of Oncology 2011;33(9):685-686
Adolescent
;
Adult
;
Aged
;
Diagnosis, Differential
;
Ependymoma
;
pathology
;
Female
;
Follow-Up Studies
;
Humans
;
Immunohistochemistry
;
Magnetic Resonance Imaging
;
Male
;
Meningeal Neoplasms
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Meningioma
;
diagnostic imaging
;
metabolism
;
pathology
;
surgery
;
Mucin-1
;
metabolism
;
Oligodendroglioma
;
pathology
;
Tomography, X-Ray Computed
;
Vimentin
;
metabolism
;
Young Adult
4.APS IgG stimulates monocytes to express TF activity,not via Fc receptor pathway
Hong ZHOU ; Junxia GU ; Wenrong XU
Chinese Journal of Immunology 2000;0(08):-
Objective:To investigate whether the IgG from patients with antiphospholipid syndrome(APS) is capable of stimulating blood monocytes to express tissue factor(TF) activity and to explore the mechanisms possibly concerned.Methods:Freshly isolated peripheral blood monocytes were cultured in media containing purified APS IgG or normal IgG or RP-1 [a monoclonal anti-?_2 glucoprotein I(?-?_2GPI)antibody] and/or other agonists and the TF activity on monocytes was investigated by measuring factor Ⅶa-dependent generation of factor Xa.Results:APS IgG as well as RP-1 significantly increased monocytes TF activity,comparing to normal IgG;exogenous ?_2GPI enhanced the effects as the intact IgG molecule.Conclusion:That certain antiphospholipid antibodies,mainly anti-?_2GPI antibodies,induce monocytes TF activity in an antigen-specific manner,not via Fc receptor pathway,is contributed to the thrombotic diathesis in APS.
6.Serum Soluble Adhesion Molecule and Its Relation with the Disease Activity in Systemic Lupus Erythematosus
Weiheng ZHOU ; Dongqing CHENG ; Weisong HONG ; Jin XU ; Aie XU
Chinese Journal of Dermatology 1995;0(01):-
Objective To investigate the relationship between the serum level of soluble vascular cell adhesion molecule-1(sVCAM-1) and soluble intercellular adhesion molecule-1(sICAM-1) and the disease activity in systemic lupus erythematosus(SLE). Methods The serum concentrations of sVCAM-1 and sICAM-1 were measured by ELISA in 60 SLE patients and age- and sex-matched normal controls. Results ① Serum levels of sVCAM-1 and sICAM-1 were significantly increased in SLE patients compared with those in normal controls (P
7.Detection of soluble vascular cell adhesion molecule-1 and soluble intercellular adhesion molecule-1 in the sera of patients with systemic lupus erythematosus
Weiheng ZHOU ; Dongqing CHENG ; Weisong HONG ; Jin XU ; Aie XU
Chinese Journal of Rheumatology 2003;0(09):-
Objective To detect the levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) and soluble intercellular adhesion molecule-l (sICAM-1) in the sera of patients with systemic lupus erythe-matosus (SLE) and their clinical significance was analysed. Methods Serum level of sVCAM-1 and sICAM-1 of 30 controls and 60 SLE patients were measured by enzyme linked immunosorbent assay (ELISA). Results 1 Serum levels of sVCAM-1 were significantly increasd in patients with SLE compared with those in normal controls (P
8.The value of tumor type M2 pyruvate kinase in the diagnosis of lung cancer
Dong WANG ; Juan ZHOU ; Min LIU ; Hong-Xu XU ;
Chinese Journal of Laboratory Medicine 2001;0(05):-
Objective To investigate the diagnostic values of tumor M2-PK in lung cancer.Methods The concentration of Tumor M2-PK in plasma was detected by ELISA in 106 health controls,77 benign lung disease patients and 92 lung cancer patients.Results TuM2-PK concentration in plasma and the positive rate were singificantly higher in lung cancer(22.1 U/m1,71%)than that in benign lung disease and in health controls(10.5 U/ml,4% and 8 U/ml,3%)(P
10.Clinical application of the peripheral stimulation in the obturator nerve block used in the TURBt
Yong YANG ; Yong XU ; Bao-Fa HONG ; Hong ZHOU ;
Cancer Research and Clinic 1999;0(05):-
Objective Observe the results and reality of the peripheral nerve stimulator in the obtu- rator nerve block in TURBt.Methods 18 cases received the peripheral nerve stimulator in obturator nerve block before TURBt.Results In 17cases obturator nerve reflection vanished;lcase had a little symptom of adductor spasm.Conclusion Obturator nerve block with the help of the nerve stimulator can increase the achievement and quality of obturator nerve block and avoid some complications caused by obturator nerve re- flection in TURBt,such as perforation of bladder and injury of nerve and vessel.