1.Drinking Water Quality and Intestinal Infectious Diseases in Urban and Rural Boarding Schools in Guangxi
Zhenzhu TANG ; Gemei ZHONG ; Hong YANG
Journal of Environment and Health 1993;0(01):-
Objective To know the drinking water safety for students and teachers in urban and rural boarding schools in Guangxi, further to prevent and control the water-borne diseases. Methods The random stratified cluster sampling method was used to select 100 schools in 10 counties of Nanning, Liuzhou and Guilin cities. The drinking water samples were collected and tested according to Sanitary Standard for Drinking Water Quality2001. The epidemic situation of intestinal infectious diseases was investigated. Results The total qualified rate of drinking water quality in 100 boarding schools of 10 counties cities was only 27.00%, as for the water supply provided for themselves with disinfection, the qualified rate was 47.37%, without disinfection, it was 16.95%. 24 outbreak events of intestinal infectious diseases occured in 100 boarding schools in 2000-2005, 2 339 of school teachers and students were attacked, including 13 outbreak events of typhoid and paratyphoid 54.17% with 1 280 cases 54.72%, 6 outbreak events of bacterial dysentery25.00% with 829 cases35.44%, 4 outbreak events of infectious diarrhea 16.67% with 225 cases 9.62%, 1 outbreak of hepatitis A 4.17% with 5 cases 0.21%. These 24 epidemic events were caused by drinking water, the morbidity was higher in the schools where there was no disinfection facility in water supply. Conclusion Some of water supply for some urban and rural boarding schools have been polluted with bacteria in Guangxi, so drinking water disinfection should be done to ensure water safety and prevent the related diseases in these schools.
2.Transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy
Liuping YANG ; Hong ZHONG ; Junhong DENG
Chinese Journal of Ultrasonography 1993;0(01):-
Objective To evaluate the safety and efficacy of transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy.Methods Seventy-three patients requiring systematic 13 cores biopsy of the prostate were randomized into two groups.Group A(37 cases) received an injection of 5 ml 1% lidocaine into the prostatic neurovascular bundles on each side at the base of the prostate under ultrasound guidance,and group B(36 cases) received 5 ml saline ( 0.9% sodium chloride) at the same way.Pain during biopsy was assessed using a 10-point linear visual analog pain scale immediately after this procedure.Results The mean pain scores during transrectal prostate biopsy were significantly lower in group A than that in group B( 1.1? 0.6 vs 5.9? 3.1,t= 4.81,P
3.Transrectal ultrasound guided systematic 13 cores prostate biopsy for diagnosing prostate carcinoma:report of 160 cases
Jianbo HU ; Liuping YANG ; Hong ZHONG
Chinese Journal of Urology 1994;0(02):-
Objective To evaluate the clinical value of transrectal ultrasound guided systematic 13 cores prostate biopsy. Methods A total of 160 patients referred for abnormal digital rectal examination and (or) prostate specific antigen 4ng/ml or greater underwent transrectal ultrasound guided systematic 13 cores prostate biopsy.That was,in addition to the standard sextant biopsies,cores were taken from the far lateral and middle regions of the gland as described by Eskew.Pathological findings of the additional regions were compared with those of the sextant regions. Results Of the patients 35 % had cancer on biopsy(56 /160).Of the 56 patients with prostate cancer 12(21%)had carcinoma only in the additional regions,which would be undetected on the sextant biopsy technique (P
4.Clinical analysis of 12 lymphoplasmacytic lymphoma cases.
Hong-liang YANG ; Yi-zhuo ZHANG ; Zhong-li ZHAN
Chinese Journal of Hematology 2012;33(4):336-339
Aged
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Biopsy
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Bone Marrow Examination
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Female
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Humans
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Lymph Nodes
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pathology
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Lymphoma, B-Cell
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diagnosis
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pathology
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Male
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Middle Aged
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Retrospective Studies
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Young Adult
5.The study of the second signal system in T cells costimulated by anti-CD28+B7.1 McAb and the induction of apoptosis of the hepatoma cells
Hong YANG ; Lisheng PENG ; Xiaofen ZHONG ; Al ET
Chinese Journal of Immunology 2001;0(10):-
Objective:To explore the action of the second signal system in the activatied and proliferating T cells and the induction of apoptosis of the hepatoma cells.Methods:The T cells were costimulated by anti CD28 and anti CD80(B7.1)McAb and acted on the hepatoma cells(BEL 7402),then testing the concentration of cAMP?cGMP and Ca 2+ in the T cells and the apoptosis of the hepatoma cells.Results:The concentration of cAMP was increased temporarily at first,then decreased rapidly,and increased 1 2 times again when acted on the hepatoma cells.The concentration of cGMP was increased 6 8 times fast and the concentration of Ca 2+ obviously increased 2 3 times too.The peak of them was at the fourth day and positive related to apoptosis of the hepatoma cells.Conclusion:The level of the second signal system of cAMP?cGMP and Ca 2+ were significant correlated with the T cells activated and porliferating and the cytotoxic effect.
6.Early use of nutritional support in patients after liver transplantation
Wenxin YANG ; Zhengjiang ZHONG ; Hong SHEN ; Xiaomei CHENG ; Jianxin MA
Parenteral & Enteral Nutrition 1997;0(04):-
Objective: To discuss the way of early nutritional support in the patients after the liver transplantation. Methods: The nutritional support was used in 28 patients who had suffered the orthopetic liver transplantation (OLT).Parenteral nutrition was started as soon as possible after the operation. On the fourth day after the operation, enteral nutrition was also used. Results: 5 patients died from the postoperative complications. 23 patients survived and had been in better nutrition. Conclusion: The early nutrition support can play an important role in the patients recovery after OLT. EN should be administrated immediately when the gut functions.
9.Effects of glycyrrhizin acid and licorice flavonoids on LPS-induced cytokines expression in macrophage.
Zhao LIU ; Ju-Ying ZHONG ; Er-Ning GAO ; Hong YANG
China Journal of Chinese Materia Medica 2014;39(19):3841-3845
Glycyrrhizin acid and licorice flavonoids are the component of Glycyrrhiza uralensis Fisch root that has been used for various medicinal purposes in traditional oriental medicine for thousands of years. Macrophages as a principal component of immune system play an important role in the initiation, modulation and final activation of immune response against pathogens. In the present study, glycyrrhizin acid and licorice flavonoids was investigated the anti-inflammatory effect on lipopolysaccharide (LPS)-induced macrophage cell line of RAW264.7. Well-grown RAW264.7 cells were collected and randomly divided into the blank control group, the LPS(1 mg x L(-1)) group, the dexamethasone (5 mg x L(-1)) with LPS group, the glycyrrhizin acid (400, 80, 16 mg x L(-1)) with LPS group and the licorice flavonoids (200, 40, 8 mg x L(-1)) with LPS group. RAW264.7 cells were cultured in 24-well plates, pre-incubated for 4 h with different concentrations of dexamethasone, glycyrrhizin acid, or licorice flavonoids. Then cells were stimulated for 20 h with LPS. The supernatant of culture medium was collected from each well and determinated the concentrations of cytokines by means of BioPlex mouse cytokines assay. Compared with the control group, the LPS group could significantly induced relatively high levels of granulocyte colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor( GM-CSF), macrophage inflammatory protein-1 alpha (MIP-1α), macrophage inflammatory protein-1 beta (MIP-1β), regulated upon activation normal T cell expressed and secreted factor (RANTES), tumor necrosis factor alpha ( TNF-α), monocyte chemotactic protein 1 (MCP-1), chemokine (C-X-C motif) ligand 1 (KC), eotaxin, interleukin(IL)-1α, IL-1β, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12 (p40), IL-12 (p70), IL-13, and IL-17 secretion (P < 0.05). The glycyrrhizin acid significantly inhibited IL-1β, IL-3, IL-5, IL-6, IL-10, IL-12 (p40), IL-12 (p70), IL-13, Eotaxin and TNF-α secreted by LPS-stimulated RAW264.7 cells (P < 0.05). The expression levels of IL-6 and Eotaxin were observably decreased in the licorice flavonoids with LPS group (P < 0.05). The data presented here suggested that the glycyrrhizin acid and licorice flavonoids modulate various cytokines secreted by macrophages and were important anti-inflammatory constituent of Licorice.
Animals
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Cell Line
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Cytokines
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genetics
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immunology
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Flavonoids
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pharmacology
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Glycyrrhiza
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chemistry
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Glycyrrhizic Acid
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pharmacology
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Lipopolysaccharides
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immunology
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Macrophages
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drug effects
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immunology
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Mice
10.Etiology of severe acute respiratory syndrome.
Chang-an ZHAO ; Zhong-zhi LI ; Yong-hong YANG
Chinese Journal of Pediatrics 2003;41(6):439-440