1.Investigation of Microcystin-LR Pollution in Large Reservoirs in Taiyuan
Zhi-Hong ZHANG ; Guo-Guo QIAO ; Hai-Fang LIU ;
Journal of Environment and Health 2007;0(08):-
Objective The aim of this paper is to know about the pollution of microcystin-LR(MC-LR)in Fenhe First reservoir and Fenhe Second reservoir in Taiyuan and provide reference for making the policy of prevention microcystin-LR pollution.Methods During the low water period(May,2005)and common period(Oct,2005),5 liter water was sampled in the entrance,the center and the exit in Fenhe First reservoir and Fenhe Second reservoir respectively.The concentrations of MC-LR in two reservoirs were determined by the high-performance liquid chromatography(HPLC).Results The average concentration (0.875 ?g/L)of MC-LR in low water period was 3 time of that(0.283 ?g/L)in common period in Fenhe First reservoir.The average concentration(0.815 ?g/L)of MC-LR in low water period was 17 time of that(0.048 ?g/L)in common period in Fenhe Second reservoir.The level of MC-LR in the entrance was the highest,that in the exit was the lowest,that in the center was middle. The concentration of MC-LR of the entrance in low water period was more than the MC-LR limit(1 ?g/L)in Life drinking water hygienic guide(2001).Conclusion MC-LR pollution has been found in Fenhe First reservoir and Fenhe Second reservoir and the pollution is serious in low water period.
2.Gastric fistulation with transcutaneous endoscopy in a child.
Zhi-hong HU ; Ming SHEN ; Li SUN ; Rong QIAO ; Fu-mei JIA ; Si-yuan YANG
Chinese Journal of Pediatrics 2004;42(3):222-223
3.Study of DiBAC4(3) for dynamic measurement of embryo membrane potentials.
Xiao-Yan DING ; Liao-Qiong FANG ; Hong ZHANG ; Hai QIAO ; Zhi-Biao WANG
Chinese Journal of Applied Physiology 2012;28(1):32-78
Animals
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Barbiturates
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Coloring Agents
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Fallopian Tubes
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cytology
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embryology
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physiology
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Female
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Isoxazoles
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Male
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Membrane Potentials
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Mice
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Mice, Inbred Strains
4.Preparation of interferon-alpha-containing liposomes by the powder bed grinding method
Zhi-Wei YE ; Qiao-Hong HU ; Wen-Quan LIANG
Journal of Zhejiang University. Medical sciences 2002;31(6):433-436
OBJECTIVE: To investigate a nwe, simple technique for preparation of interferon-alpha-liposomes, which may be suitable for industrial use. METHODS The uniform design coupled with computerized optimization was utilized to screen the formulation and preparation procedure of interferon-alpha-liposomes. Pro-liposomes were prepared by the powder bed grinding method and combined with interferon-alpha-solution to form interferon-alpha-liposomes. Liposome size was determined by the particle size analyzer. Free interferon-alpha and interferon-alpha-liposome were separated by gel filtration. Then the recovered activity of interferon-alpha was analyzed by enzyme-linked immunosorbent assay. RESULTS The result demonstrated that the best interferon-alpha-liposome formulation was as follows: the protectant was sorbitol; weight ratio of protectant to lipid was 5:1; weight ratio of octadecytamin to lipid was 1:9; weight ratio of sobey phosphatidylcholine to cholesterol was 9:1 respectively. Interferon-alpha-liposome size determined by the particle size analyzer was 80.8+/-36 nm and the encapsulation efficiency was 59.0+/-3.3%. CONCLUSION The powder bed grinding method can be used to prepare pro-liposomes which can be easily combined with interferon-alpha-solution to form interferon-alpha-liposomes.
5.Wolffian adnexal tumor: report of a case.
Ren-qiao LIU ; Zhen-huan ZHANG ; Min-hong PAN ; Zhi-hong ZHANG ; Qin-he FAN
Chinese Journal of Pathology 2013;42(7):476-477
Adenoma
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metabolism
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pathology
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surgery
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ultrastructure
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Adnexa Uteri
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pathology
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surgery
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Adnexal Diseases
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metabolism
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pathology
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surgery
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Carcinoma, Endometrioid
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metabolism
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pathology
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Diagnosis, Differential
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Female
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Granulosa Cell Tumor
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metabolism
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pathology
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Humans
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Hysterectomy
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Keratins
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metabolism
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Leiomyomatosis
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pathology
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surgery
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Microscopy, Electron
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Middle Aged
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Neoplasms, Multiple Primary
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metabolism
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pathology
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surgery
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ultrastructure
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Sertoli-Leydig Cell Tumor
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metabolism
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pathology
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Uterine Neoplasms
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pathology
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surgery
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Vimentin
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metabolism
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WT1 Proteins
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metabolism
6.An atypical case of mitochondrial acetoacetyl-CoA thiolase deficiency
Chun-Hui Hu ; Qiao-Qiao Qian ; Hong-Min Zhu ; Dan Sun ; Shu-Hua Wu ; Ge-fei Wu ; Jia-Sheng Hu ; Zhi-Sheng Liu
Neurology Asia 2017;22(2):165-169
Methylacetoacetyl-CoA thiolase deficiency (T2 deficiency) is a rare congenital and metabolic disease
affecting the ketone body and isoleucine metabolism. The typical symptoms are refractory metabolic
acidosis, in which large amounts of 2-methyl-3-hydroxybutyry1 carnitine, 2-methyl-3-hydroxybutyrate
and tiglylglycine are often detected in the blood and urine. We herein describe an atypical case of T2
deficiency with a high level of 3-hydroxybutyrate and a low level of 2-methyl-3-hydroxybutyrate in
the urine. Such a case was diagnosed by urinary organic analysis in combination with gene mutation
evaluation. Organic acids in the urine were measured using a gas chromatography mass spectrometer
and all exons were sequenced via deep sequencing. Molecular biology analysis confirmed the presence
of a homozygous mutation in the acetyl-CoA acetyltransferase 1 (ACAT1) gene. The patient received a
special diet of deeply hydrolyzed protein milk powder and raw corn starch. She was followed about 6
months. There were no ketoacidotic episodes and hypoglycemia even when she had fever. In conclusion,
patients with atypical features of T2 deficiency should also be investigated early. Gas chromatography
mass spectrometry and next-generation full exome sequencing may be helpful in diagnosis.
7.Application of the life sciences platform based on oracle to biomedical informations.
Zhi-Yun ZHAO ; Tai-Huan LI ; Hong-Qiao YANG
Chinese Journal of Medical Instrumentation 2008;32(2):128-130
The life sciences platform based on Oracle database technology is introduced in this paper. By providing a powerful data access, integrating a variety of data types, and managing vast quantities of data, the software presents a flexible, safe and scalable management platform for biomedical data processing.
Computational Biology
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Database Management Systems
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Medical Informatics Applications
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Software