1.Correlation between atherosclerotic renal artery stenosis and coronary heart disease and the inflammation related factors
Chinese Journal of Practical Internal Medicine 2000;0(11):-
Objective To investigate the correlation between atherosclerotic renal artery stenosis and the severity of coronary lesions in patients with confirmed coronary artery disease and the impact of renal artery stenosis on serum inflammation related factors.Methods 163 patients from Peking University First Hospital with confirmed coronary heart disease by coronary angiography underwent selective renal artery angiography from Dec 2002 to Sep 2003.Serum hypersensitive C reactive protein(hs-CRP)and Interleukin-6(IL-6)were measured.Results Patients combined with coronary disease and renal artery stenosis were presented with more acute coronary syndrome(ACS)and triple-vessel CAD.Serum hs-CRP and IL-6 levels were also higher in this group.Conclusion Renal artery stenosis is correlated with severe coronary disease.Inflammation state could be one of the reasons for this connection.
2.The methods to raising teaching quality of water-electrolyte metabolism and acid-base balance disorders
Chinese Journal of Medical Education Research 2002;0(01):-
This article has shown the experiences to achieve more effective teaching results by integration of multiple teaching patterns,including case-based,problem-based learning,in the teaching of water-electrolyte metabolism and acid-base balance disorders.
3.Application of scene Imitation in the education of patients before fiberoptic bronchoscopy
Ke HE ; Hong DONG ; Chunmei YAN
Chinese Journal of Primary Medicine and Pharmacy 2009;16(2):240-241
Objective To explore the application and effect of scene imitation method in the education of patients before fiberoptic bronchoscopy.Methods 264 elective bronchoscopy patients between March 2007 and Decembet 2007 were randomly divided into control group(120 patients)and the experiment group(144 patients)Traditional health education was applied in the control group before bronehoscopy.Scene imitation method in health education was applied in the experiment group before bronchoscopy.Results The examination succes rate in the experiment group was significantly improved(P<0.05).The medical order obeying behavior(MOOB)of the patients was significantly different between the two group(P<0.01).Conclusion Before the use of fiberoptic bronchoscopy,the new scene simulation method Can help patients on the list obtain more cognitive ability about the testing.Comparing the traditional education,it establishes a sound relationship between doctors and patients,reduces complication and leads to more accurency of testing,thus helping patients to recover soon.
4.Clinical experience of ultrasound-guided percutaneous nephrostomy
Lihong HE ; Yan LI ; Jingfan HONG
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To summarize the experience of ultrasound-guided percutaneous nephrostomy during percutaneous nephrolithotomy(PCNL) under B-ultrasound guidance. Methods A ultrasound-guided percutaneous nephrostomy was performed in 43 cases by using a 18-gauge needle.Then the percutaneous puncture was expanded for establishing a working tunnel. Under nephroscope,stone fragmentation was completed in the renal pelvis and the upper segment of the ureter.Results The success rate of percutaneous puncture was 100%.Of the 43 cases,the percutaneous working tunnel was successfully established in 42 cases(97.7%),while a conversion to open surgery was needed in 1 case because of uncontrolled hemorrhage after puncture.The overall stone clearance rate was 100%(42/42),including 38 cases of stone removal on one session and 4 cases of two-staged clearance.No serious complications,such as massive hemorrhage or neighboring organ injuries,were encountered.Re-examinations with B-ultrasonography or KUB at 1 month after operation showed no residual stones.Conclusions Ultrasound-guided percutaneous nephrostomy is minimally invasive,safe,and reliable.Proper use of this technique is crucial for a successful performance of percutaneous nephrolithotomy in the treatment of upper urinary tract calculus.
5.Study on relationship between atherosclerotic renal artery disease and target organ harm in hypertension patients
Chinese Journal of Interventional Cardiology 2003;0(05):-
Objective To investigate the correlation between atherosclerotic renal artery stenosis and hypertension.Methods One hundred and seventy-nine patients underwent renal artery angiography after coronary artery angiography. Results Among the 179 patients, 56.4% patients were detected as renal artery normal, 24% as renal artery disease, and 19.6% as renal artery stenosis. Compared with hypertensive patients with normal renal artery, ARAS patients had higher systolic blood pressure (148?23 mm?Hg vs 136?18 mm?Hg, P
6.Efficacy of PFNA and Gamma nail in treatment of intertrochanteric fractures in elderly
Hong DING ; Yingying HE ; Yan CHEN
Journal of Regional Anatomy and Operative Surgery 2014;(3):272-274
Objective to observe the efficacy and application value of PFNA and Gamma in the treatment of intertrochanteric fractures in elderly. Methods 100 patients with intertrochanteric fractures were divided into PFNA group and Gamma group, who received PFNA treatment and Gamma treatment respectively. And the operation status of patients at different ages,postoperative recovery,and complications were observed. Results The operation time,intraoperatve blood soss of PFNA group were lower than those of Gamma group(P<0. 05). There was no significant difference in fracture healing time. The Harris score of the over 75s in PFNA group was higher than that in Gamma group(P<0. 05),and the complications were less than Gamma group(P<0. 05). Conclusion PFNA was suitable for the patients at differ-ent ages with the advantages of more rigid fixation,good anti-rotation,fewer trauma and fewer complications.
7.Utilization of health resources by rural public health centers in Hubei Province in the Ninth Five-Year Plan period
Hong YAN ; Shaobin HE ; Hui QIU
Chinese Journal of Hospital Administration 1996;0(02):-
Objective To find out about the utilization of health resources by rural pulic health centers in Hubei Province in the Ninth Five-Year Plan period so as to provide primary information for the better use of rural health resources. Methods The issues of Hubei Health Statistics and Hubei Almanac in 1990 and from 1996 to 2000 were collected and statistial analyses were conducted by means of the spss software. Results In the Ninth Five-Year Plan period, the human resources and fixed assets of rural public health centers in Hubei Province kept increasing whereas the volume of services dropped year by year. The reduction in the average number of outpatient visits and discharged patients per annum was respectively 4. 42% and 4. 09%. The efficiency of the health personnel in delivering medical services has been decreasing, with the average number of patients treated by each person per annum, the annual number of beds utilized, and the annual number of discharged patients in 2000 dropping respectively by 27.54% , 30.22% and 26.36% , as compared with 1996. The annual ratio of bed utilization was around 30% and the number of bed turnovers was about 20 times, evidencing, moreover, a tendency of going down. Conclusion The input of health resources in the rural public health centers in Hubei Province in the Ninth Five-Year Plan period increased while the rate of utilization dropped. It is suggested that integrated management in the rural areas be adopted, better utilization of health resources made, reform of the public health centers deepened, and internal management improved; greater stress be laid on improving the quality of rural health personnel; and the rural cooperative medical and health system be perfected.
8.Acupuncture at Yinlingquan (SP 9), Taichong (LR 3) mainly plus blood-letting therapy for 52 cases of gout.
Hong-Yan SHAO ; Tian-You HE ; Li ZHANG
Chinese Acupuncture & Moxibustion 2013;33(6):526-526
Acupuncture Therapy
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Adult
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Aged
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Bloodletting
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Female
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Gout
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therapy
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Humans
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Male
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Middle Aged
9.Accuracy of point-of-care testing for blood glucose monitoring in critically ill patients:evaluation of glucase oxidase and glucose dehydrogenase methods
Tao FENG ; Lijuan HE ; Xiangyuan CAO ; Hong YAN
Chinese Journal of Anesthesiology 2013;(1):58-61
Objective To evaluate the accuracy of point-of-care testing (POCT) for blood glucose monitoring in critically ill patients.Methods Two hundred and forty critically ill patients,of both sexes,aged 20-88 yr,with Acute Physiology and Chronic Health Evaluation Ⅱ score of 1-45,were enrolled.The venous,arterial and capillary blood samples were collected to determine the real-time blood glucose level using glucose oxidase (GOD) and glucose dehydrogenase (GDH) methods.The blood glucose level measured by central laboratory hexokinase method simultaneously was served as standard level.Error Grid analysis (EGA) and Bland-Altman analysis were used to determine accuracy and consistency,respectively.The accuracy of real-time blood glucose levels within the consistent limits was evaluated.Results 1.The results of EGA showed that 98.7 %,98.3 %,98.3 %(GDH method) and 96.2%,96.6%,96.7% (GOD method) of the difference between venous,arterial and capillary blood glucose levels measured and the standard level were located in the A and B zones,respectively,and 1.2%,1.7%,1.7% (GDH method) and 2.9%,3.3%,3.3% (GOD method) in the D zone.0.8% (GOD method) of the difference between venous blood glucose levels and the standard level were located in the C zone.2.Bland-Altman analysis showed that the difference between the standard level and glucose level measured in blood samples from the vein,artery and capillary.was-0.1,-0.3,-0.2 mmol/L (GDH method) and-0.9,-1.0,-0.9 mmol/L (GOD method),respectively,and the incidence beyond the upper and lower limits of consistency zone was 4.5 %,6.7 %,6.6 % (GDH method) and 4.6 %,5.0 %,7.1% (GOD method),respectively.The accuracy of venous,arterial and capillary blood glucose levels within the consistent limits was 94.3 %,92.1%,93.7% (GOD method) and 96.6%,95.1%,95.5% (GDH method),respetively.Conclusion The accuracy of POCT for blood glucose monitored by GOD and GDH methods is good in critically ill patients,but it is possible to overestimate the patient's real glucose level.
10.Effects of bone marrow mesenchymal stem cells supernatant on hippocampal GFAP expression and learning and memory in rats with neonatal hypoxic ischemic brain damage
Xiaoming ZHONG ; Huabin WANG ; Kaiyuan LUO ; Hong YU ; Yan HE
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(11):982-985
Objective To analyze the expression of glial fibrillary acidic protein(GFAP) in hippocampal of rats with hypoxic-ischemic brain damage(HIBD) after injection of bone marrow stromal cells(BMSCs) supernatant into the lateral ventricle of the neonate rats,assess the ability of learning and memory,and explore the mechanism.Methods 7-day-old SD rats were randomly divided into sham operation group,model group,cells and supernatant group,with 20 rats in each group.The HIBD model was established via the ligation of left carotid arteries followed by 2-hour hypoxia.One week later,rats in control group were injected with 0.01 mol/L PBS 2 μl via the left ventricle.Meanwhile,the cell and the supernatant groups were injected with BMSCs and supernatant harvested from BMSC culture,respectively,via the same route.In the sham operation group,the left carotid arteries were separated but not ligated,and no hypoxia treatment was imposed on this group.They also received 0.01 mol/L PBS injection 2 μl per weak post surgery.8 weeks later,Morris water maze test was performed to assess the learning and memory,and the expression of GFAP in the dentate gyrus of rats was measured by immunohistochemistry.Results Morris water maze showed that the searching time of the probe trail(T1:(15.40±2.80) s) and reversal probe trail (T2:(16.45± 1.16) s) of the model group was shorter than that of the sham operation group (T1:(19.96±2.57) s,T2:(2:25.32±2.54)s,P<0.05),while the searching time of the cell group(T1:(17.54± 1.80)s,T2:(18.99± 1.47) s) and supernatant group (T1:(17.40±2.37) s,T2:(17.96± 1.09) s) was prolonged compared with that of the model group (P<0.05).No significant difference between the cell group and the supernatant group (P>0.05).The integral optical density (IOD) value of GFAP positive cells was higher in the model group than that in the sham operation group(15.26±1.49 vs 12.82±2.56,P<0.05),while the IOD of cell group(18.13±1.97) and that of the supernatant group(17.38± 1.64) were higher than that of the model group (P<0.05).However,there was no significant difference between the cell group and the supernatant group (9>0.05).Conclusion BMSC supernatant injected through lateral ventricle can improve the HIBD rats' abilities of learning and memory.The mechanism might be that MSCs secrete some cytokines to promote central nervous system repair.