OBJECTIVE To investigate the application of antibacterials in patients accepted operation in grass-roots(hospitals),so to standardize the application of antibacterials and cut down the medical cost.METHODS Full-time administrators for nosocomial infection investigated the application of antibacterials in patients who accepted(operation) in Sep 2004,and filled in the questionnaires.RESULTS In 1 383 cases of 11 hospitals the application rate of antibacterials was 98.63%;in which 86.50% were for prophylactic usage and 13.50% for therapeutic usage;(29.90%) for single antibiotics treatment and 50.15% for bigeminy,18.70% were for trigeminy.Time of(application) differentiated(6.90,7.00,6.60d) fromⅠto Ⅲ kinds of operation.Per capita cost of antibacterials was $956.50(47.60%).CONCLUSIONS High cost of antibacterials results from such factors as multiple kinds,long time and(combined) application.

Advances in mechanism and application of the heating effect in breeding of microorganism are reviewed in this paper. Heat produces mutagenesis effect and screening effect. Heating mutagenesis effect is occurred through the substitution of G-C base pair induced by heat, and heating screening effect produces higher forward mutation rate induced by other mutagens.

This device is used to measure the tension and the strength of a experimental healed wound in the research on stimulating the wound healing using vitamin A and vitamin C.The effect of vitamin A and vitamin C to the wound healing degree can be distinguished by using this device.

OBJECTIVE: To investigate the method of surgical management for cervical esophageal carcinoma and the feasibility of the operation with preservation of laryngeal function. METHOD: Sixteen patients with cervical esophageal carcinoma who received surgical treatment were reviewed in our retrospective study. Removal of total hypopharynx and larynx and the inversion stripping esophagectomy were conducted in thirteen patients, of which one underwent the reconstraction with residual larynx and tracheal flap and the other twelve patients underwent the reconstraction with gastric-pharyngeal anastomosis. One patient received the cervical esophagectomy and partial hypopharyngectomy with laryngotracheal flap. The inversion stripping esophagectomy with laryngeal function preservation were conducted in two patients, who received the reconstraction with gastric-pharyngeal anastomosis and preserved total larynx. All the patients were carried out the bilateral neck dissections. RESULT: The surgical resection rate was 100% and no operative death occurred. The postoperative complications included pulmonary infection in two cases, anastomotic fistula in two cases, anastomotic stenosis in two cases and congestive heart failure in one case. The retained rate of the laryngeal function is 12.5%. The 3-year survival rate is 30.7%, and the 5-year survival rate is 23.1%. CONCLUSION The surgical treatment of cervical esophageal carcinoma is possible. The inversion stripping esophagectomy without thoracotomy is performed to resect the tumor. The esophageal defect could be reconstructed by laryngotracheal flap or gastric-pharyngeal anastomosis. The laryngeal function should be remained as far as possible according to the location and extension of the tumor.
Aged ; Esophageal Neoplasms ; surgery ; Esophagectomy ; methods ; Female ; Humans ; Male ; Middle Aged ; Neck ; Retrospective Studies

Objective To explore whether chlamydia pneumoniae(CP) infection causes the coronary artery morphology change in children and their reciprocity.Methods Serum immunoglobin M(IgM) and immunoglobin G(IgG) antibody to CP were detected by enzymelinked immunosorbent assay(ELISA) in 52 hospitalized children aged 1 month to 10 years and 5 months old in respiratory ward in our hospital,serum interleukin-6(IL-6),triglyceride(TG) and peripheral blood C-reactive protein(CRP) were also determined,morphology change of coronary artery of the patients were harvested by colored doppler echocardiogram.Results In the 52 cases,21 cases were positive of IgM,28 cases were positive of IgG,3 cases were positive both IgM and IgG.Twelve cases were high of CRP,5 cases were high of IL-6,9 cases were high of TG.In the 52 patients,the different levels of IgM,IgG,IL-6,CRP and TG had not coronary artery morphology change.Conclusion CP infection in the children does not cause the coronary artery to occur morphology change.

OBJECTIVETo explore the correlation between the recurrence of cerebral infarction and aspirin resistance (AR)/Chinese medical (CM) constitutions.

METHODSTotally 413 cerebral infarction patients took Aspirin Enteric-coated Tablet (100 mg per day) while receiving routine therapy, 5 days at least in a week. They were followed-up for 12 months. Aspirin sensitivity (AS) was determined using turbidimetry. CM constitutions among patients with different AS were compared. Ratios of AR patients and AS patients of different CM constitutions in cerebral infarction recurrent patients were compared. Platelet membrane glycoproteins (GP) II b HPA-3 gene polymorphism was detected by polymerase chain reaction (PCR) method. Correlation between recurrence of cerebral infarction and AR, bb genotypes, CM constitutions times AS were analyzed by Logistic regression.

RESULTSTotally 11 patients dropped out, 101 (25.12%)with recurrent cerebral infarction and 301 (74.88%) without recurrent cerebral infarction. There were 152 (37.81%) AR patients and 250 (62.19%) AS patients. AR accounted for 26.6% (80/ 301) and AS accounted for 73.4% (221/301) in non-recurrent cerebral infarction patients. AR accounted for 71.3% (72/101) and AS accounted for 28.7% (29/101) in recurrent cerebral infarction patients. There was statistical difference in AR and AS ratios (χ2 = 64.287, P = 0.000). The proportion of yin deficiency constitution (YDC) was the largest [28.3% (43/152)] in AR patients. The proportion of blood stasis constitution (BSC) was the largest [23.6% (59/250)] in AS patients. There was statistical difference in CM constitutions between AR patients and AS patients (χ2 = 21.574, P < 0.01). The former 4 recurrent rates occurred in AR patients of YDC, BSC, damp-phlegm constitution (DPC), qi deficiency constitution (QDC). YDC occupied the first place [22.4% (34/152)]. The former 4 recurrent rates occurred in AS patients of BSC, QDC, DPC, damp-heat constitution (DHC). BSC occupied the first place [3.2% (2/250)]. Compared with non-recurrent cerebral infarction patients and AS patients, bb gene occurred most often, but aa gene and ab gene occurred obviously lesser in non-recurrent cerebral infarction patients and AR patients (χ2 = 20.171, χ2 = 55.139, P < 0.01). AR and bb gene were positively correlated with recurrent cerebral infarction (OR = 18.423, P = 0.000; OR = 1.304, P = 0.028). Body constitutions interacted with AS (OR = 0.707, P = 0.000).

CONCLUSIONSRecurrent cerebral infarction was closely related to AR and constitutional types. The recurrence rate was higher in AR patients of YDC. GP I b HPA-3 bb genotype might be a risk factor for AR and recurrent cerebral infarction.

Aspirin ; therapeutic use ; Body Constitution ; Cerebral Infarction ; Drug Resistance ; Humans ; Medicine, Chinese Traditional ; Neoplasms ; Recurrence ; Yin Deficiency

Objective To investigate the effect of prognostic factors and nursing care in of acute myocardial infarction(AMI)patients performed emergency percutaneous coronary intervention supported by IABP.Methods Twenty seven AMI patients treated with emergency PCI,supporting by intra-aortic balloon pump(IABP).We analyzed retrospectively elinical characters and situation of interventional treatment of the patients.Results Among 27 cases.there were 12 cases who were recovered,4 suffered congestive heart failure repeatedly.and ll died during the hospitalization.There was no difference in age,sex,the history of hypertension,diabetes and smoking,the site of infarction and ejection fraction of left ventficular.The prognosis was different in the patients with grade of Killip in cardiac function and no flow post PCI(P<0.05).Conclusions The grade of Killip and no flow post PCI were the effective factors for prognosis in Acute Myocardial patients with emergency PCI.

Objective To explore the effect of specialized care of iodophor uterine cavity wipe on prevention of incision infection in acute cesarean section pregnant women.Methods A total of 50 patients with acute cesarean section were enrolled in this study,and were randomly divided into two groups.The patients in the control group were given routine nursing,while the patients in the experimental group were treated with special care and iodophor cavity wipe,cesarean section related parameters,the relevant clinical indicators,clinical events,subjective feelings and family care satisfaction were compared.Results The scores of SAS and SDS,systolic blood pressure,diastolic blood pressure,heart rate,total white blood cell count,postoperative pain score,time to first bed-off,time to first exhaust,time to first breast milk,feeding times of alternative milk,postoperative 24 h body temperature and the rate of incision infection in the observation group were lower than that of the control group (P ＜ 0.05).The scores of breastfeeding and subjective feeling were higher in the experimental group than in the control group (P ＜ 0.05).The satisfaction degree of the family members was better than that of the control group (P ＜ 0.05).Conclusion The application effect of special care and iodophor uterine cavity wiping in the treatment of acute cesarean section pregnant women are obvious,and it can improve nursing satisfaction,so it is of great significance in promotion.

Objective To explore the effect of specialized care of iodophor uterine cavity wipe on prevention of incision infection in acute cesarean section pregnant women.Methods A total of 50 patients with acute cesarean section were enrolled in this study,and were randomly divided into two groups.The patients in the control group were given routine nursing,while the patients in the experimental group were treated with special care and iodophor cavity wipe,cesarean section related parameters,the relevant clinical indicators,clinical events,subjective feelings and family care satisfaction were compared.Results The scores of SAS and SDS,systolic blood pressure,diastolic blood pressure,heart rate,total white blood cell count,postoperative pain score,time to first bed-off,time to first exhaust,time to first breast milk,feeding times of alternative milk,postoperative 24 h body temperature and the rate of incision infection in the observation group were lower than that of the control group (P ＜ 0.05).The scores of breastfeeding and subjective feeling were higher in the experimental group than in the control group (P ＜ 0.05).The satisfaction degree of the family members was better than that of the control group (P ＜ 0.05).Conclusion The application effect of special care and iodophor uterine cavity wiping in the treatment of acute cesarean section pregnant women are obvious,and it can improve nursing satisfaction,so it is of great significance in promotion.

Objective Todiscussandestablishaquantitativesupervisionindexoffoodsafetyforlarge-scaleoutdoor activities,andtoprovidescientificbasisforthestudyofsupervisionsystemforfoodsafety.Methods Delphiexpert consultation method was used to establish the supervision index system of food safety for large-scale outdoor activities,and the weight of the indicators were determined.Indexes were screened based on 5 -point liker scale,and weight was determinedonthebasisofproportionmethod.Results Theaverageserviceyearofthe21expertswere21.52±9.05.The response rates were both 1 00% in two rounds of consultation,and the average authoritative coefficients were 0.78 ±0.03 and 0.79 ±0.03,respectively.Kendall's coefficient was 0.46 in the first round and 0.51 in the second round.The secondary indicators was 0.38 in the first round and 0.33 in second round (P <0.01 ).A total of 6 primary and 32 secondary indicators were identified and at the same time their weights were measured.The alert line was 75 .Conclusion Foodsafetyriskoflarge-scaleoutdooractivitieswassignificantlyhigherthanthatoflarge-scaleindooractivities.The study of quantitative supervision index system of food safety for large-scale outdoor is practical.It can provide scientific evidence and technical support for the supervision of food safety.