Biomarkers, Tumor ; analysis ; Breast Neoplasms ; metabolism ; pathology ; Female ; Guidelines as Topic ; Humans ; Immunohistochemistry ; methods ; In Situ Hybridization, Fluorescence ; methods ; Quality Control ; Receptor, ErbB-2 ; metabolism

Biopsy, Large-Core Needle ; Coloring Agents ; Hematoxylin ; Humans ; Immunohistochemistry ; Lymphoma ; pathology ; Pathology ; standards ; Pathology, Molecular ; Staining and Labeling

Acupuncture Therapy ; Adult ; Aged ; Bloodletting ; Combined Modality Therapy ; Crying ; Female ; Humans ; Laughter ; Male ; Middle Aged ; Stroke ; psychology ; therapy ; Treatment Outcome

[Objective]To evaluate the methods of operation and clinic effective of thoracolumbar spinal tuberculosis with paraplegia.[Method]Thirty cases of thoracolumbac spinal tuberculosis with paraplegia had been treated with primary anterior debridement,decompression of spinal cord,interbody graft bone,and interbody fixation,anti-tuberculosis drug was taken at 18 monthes ofter the operation.[Result]Thirty cases were followed-up for an overage of 19 months and were healed,in which 2 cases recurrence,29 cases spinal fusion of graft bone,12? of kyphosis correction had been gained,the neuropathic fuction had gained improvement excellently(90%).[Conclusion]It had gained good outcome that operation of the primary anterior debridement decompression of spinal cand interbody graft bone and interbody fixation to treat thoracolumbac spinal tuberculosis with pacaplegia.

Cerebral Hemorrhage ; etiology ; Cerebrospinal Fluid Rhinorrhea ; surgery ; Humans ; Male ; Middle Aged ; Postoperative Hemorrhage

3 cases with esophageal fistula following anterior cervical fixation were reported. The diagnosis, treatment, nursing and prevention were summarized with literature.

Acid Phosphatase ; metabolism ; Alkaline Phosphatase ; metabolism ; Animals ; Carcinoma ; metabolism ; pathology ; HSP70 Heat-Shock Proteins ; metabolism ; Male ; Mice ; Proliferating Cell Nuclear Antigen ; metabolism ; Stomach Neoplasms ; metabolism ; pathology

Objective: To determine the optimal manipulation parameters in Liu's back tuina therapy for remission-stage cough variant asthma (CVA) in kids. Methods: A 5-factor 3-level L18(37) orthogonal design was adopted. The experimental factors and levels were selected: A, the number of times of Rou-kneading Feishu (BL 13); B, the frequency of Rou-kneading Feishu (BL 13); C, the number of times of Tui-pushing in a '介'-like pattern; D, the frequency of Tui-pushing in a '介'-like pattern; E, the intensity of red color after Ca-scrubbing Feishu (BL 13) with salt. A1, A2 and A3 stood for 10 times, 20 times and 30 times, respectively; B1, B2 and B3 stood for 200 times/min, 240 times/min and 280 times/min, respectively; C1, C2 and C3 stood for 50 times, 75 times and 100 times, respectively; D1, D2 and D3 stood for 150 times/min, 175 times/min and 200 times/min, respectively; E1, E2 and E3 stood for pinkish, bright red and dark red, respectively. A total of 108 kids with CVA in remission stage were divided into 18 groups using the random number table method, with 6 cases in each group. Changes in the cough score and fractional exhaled nitric oxide (FENO) level were observed after 15-day treatment. Results: The cough score and FENO level changed significantly in every group after treatment (all P<0.01). By the effect in improving cough score, the factors were listed as D, B, A, C and E in descending order; the most optimal manipulation parameter combination was group 17 (A3B2C1D3E1); the second optimal parameter combinations were group 7 (A3B1C2D1E3), group 13 (A2B1C2D3E1) and group 14 (A2B2C3D1E2). Regarding the effect in down-regulating the level of FENO, the factors were listed as C, A, E, B and D in descending order; the most optimal manipulation parameter combination was group 13 (A2B1C2D3E1); the second optimal parameter combinations were group 18 (A3B3C2D1E2), group 16 (A3B1C3D2E3) and group 14 (A2B2C3D1E2).Conclusion: Two most effective manipulation parameter combinations were selected out of 18 different parameter combinations in Liu's back tuina therapy for remission-stage CVA in kids. Doctors can choose an appropriate manipulation based on the symptom features of the disease.

Objective To investigate the effect of problem- based learning (PBL) combined with evidence- based medicine (EBM) on clinical teaching for postgraduates of spinal cord injury rehabilitation. Methods Postgraduates who studied in our ward between April 2010 to March 2012 were enrolled as control group (n=12) and received traditional teaching. Postgraduates who studied in our ward between April 2012 to March 2014 were enrolled as test group (n=12) and received PBL combined EBM in addition. Their achievement of academic and practical (case analysis) tests were compared, and they were investigated with questionnaire of satisfaction. Results There was no significant difference between the groups in achievement of academic and practical (case analysis) tests (P>0.05). The score of progressive knowledge was significantly higher in the test group than in the control group (P<0.01). The results of questionnaire showed that the level of literature retrieval, English, self-learning and analyzing-summarizing improved more in the test group than in the control group (P<0.05). There was no significant difference between the groups in terms of improvement of clinical thinking, nor of the satisfaction about teacher and teaching method (P>0.05). Conclusion PBL combined with EBM can improve the teaching for postgraduates majored in spinal cord injury rehabilitation.

Earthquake can result in a large number of patients with spinal cord injury(SCI).The unique characteristic of spine trauma with SCI leads to challenges in the search-and-rescue phase and early trauma care for these patients.Rescue workers should be aware of the importance of spinal immobilization in people who is suspected of SCI.Special considerations are indicated for children less than 7 years old.The ABCs should be implemented as a primary resuscitative effort.Acute respiratory and hemodynamic failure after SCI should also require careful management at the scene.All efforts are aimed primarily at reducing the morbidity associated with acute SCI and increasing the survival rate of patients with SCI.