The feature extraction and feature selection are the important issues in pattern recognition. Based on the geometric algebra representation of vector, a new feature extraction method using blade coefficient of geometric algebra was proposed in this study. At the same time, an improved differential evolution (DE) feature selection method was proposed to solve the elevated high dimension issue. The simple linear discriminant analysis was used as the classifier. The result of the 10-fold cross-validation (10 CV) classification of public breast cancer biomedical dataset was more than 96% and proved superior to that of the original features and traditional feature extraction method.
Algorithms ; Artificial Intelligence ; Breast Neoplasms ; classification ; diagnosis ; Discriminant Analysis ; Female ; Humans

Objective Selected three different birth years of cases in Beijing Sijiqing Hospital,to analyze the rate of vaginal delivery and the change of vaginal delivery rate in different factors with the changing time,put forward in a new era measures to increase the rate of vaginal delivery.Methods Chose three different time(1997.10.1 -2000.9.10),(2004.10.1 -2007.9.30) and (2011.10.1 -2014.9.30) in Beijing Sijiqing Hospital obstetric patients hospitalized term delivery into groups A,B and C.The three groups of patients were retrospectively analyzed to study the change of the vaginal delivery rate.Results In different age,different factors in the vaginal births,with the development of the society,the change of national policy,the hospital vaginal births to fall after A rise trend,group A and group B,group C vaginal births were 83.45%,54.27% and 83.45% respectively,but still vaginal births in group C was lower than that of group A.There was significant difference in the rate of vaginal delivery among the three groups(χ2 =6.448,P <0.05).Conclusion As protect the majority of maternal health,increase the vaginal delivery rate by strengthening health education to improve midwifery skills,improve environmental conditions and other delivery methods.

Objective To explore the effects of cryopreservation on biological characteristics of cultured limbal stem cells.Design Experimental study.Participants Twenty New Zealand white rabbits.Methods Twenty New Zealand white rabbits(40 eyes) were preparated of peripheral cornea with 2 mm and 2 mm circular shallow conjunctival limbal graft.Rabbit limbal stem cells(Rb-LSCs) used for cell-suspention culture were isolated form New Zealand white rabbit limbal tissues.The limbal stem cells,having formated monolayer cultured limbal stem cells,were cryopreservated one month,then thawing.By immunofluorescence staining,flow cytometry,inverted microscope,MTT assay,we compared the subculture of limbal stem cells cryopreservation before and after the structure and properties.Main Outcome Measurements Limbal stem cell activity and biological characteristics.Results Compared with freshing cells,the cells after cryopreservation in morphology were poor adherence late,small nuclear cytoplasm ratio,irregular shape.Im munofluorescence staining to detect the low-temperature frozen cells ABCG2 monoclonal antibody 81.7% positive rate decreased to 46.9%,the difference was statistically significant(P

Many malfunctions may happen in the operation of plasma sterilization machine.The basic principle and running procedure of plasma sterilization system under normal condition are introduced,and the causes of malfunctions are mainly analyzed so that users can discover and obviate them immediately.

Objective To study the adverse effects on periodontal tissues caused by crownless roots in elderly people with osteoporosis. Methods Totally 60 12?week SD rats(30 male and 30 female)were randomly divided into the control group(10 male and 10 female sham?operated rats)and the osteoporosis group(20 male and 20 female castrated rats). After 12 weeks,the bone mineral density of right femora was measured by dual energy X?ray for all rats to confirm osteoporosis. The right molar crown was pinched off with haemostatic forceps and the molar root was retained. The 10 con?trol rats and the 20 experimental rats were sacrificed respectively at postoperative 2 and 4 weeks. The periodontal tissues of right molar were sampled and the morphology of the parodontium and the alveolar bone was observed by haematoxylin and eosin(HE)staining and the expression of tumour necrosis factor?alpha(TNF?α)and inducible nitric oxide synthase?2(NOS2)was detected by immunohistochemical staining and real time fluores?cent quantitative PCR(qRT?PCR). Results The HE slices indicated that the periodontal tissues in the osteoporosis group were significantly im?paired compared to the control group as the structure of parodontium loosened. Bone impairment aggravated over time. TNF?αstaining showed as a few claybank spots on the parodontium in the control group,while the staining colour was darkened in the osteoporosis group. The expression of TNF?αmRNA was significantly higher in the osteoporosis group than in the control group(P<0.05). The result of NOS2 was contrary to that of TNF?α. The differences in TNF?αand NOS2 were not statistically significant at 2 and 4 weeks(P>0.05). Conclusion The crownless roots in rats with os?teoporosis cause adverse effects of periodontal tissues as the roots accelerate absorption of the surrounding alveolar tissues. It is indicated that crown?less roots in elderly people with osteoporosis should be removed as soon as possible.

Objective To investigate the prevalence of gastroesophageal reflux disease(GERD)in outpatients who visited department of internal medicine in hospitals of Zhejiang province and its risk fac- tors were analyzed.Methods The epidemiologic study was carried out on outpatients with reflex diagnos- tic questionnaire(RDQ).The data was analyzed with Logistic regression methods.Results The preva- lence of GERD in those patients was 7.28%(95% CI:6.87%-7.69%)in preliminary screening.There was significant correlation among gender,age,degree of labour intensity,status of marriage and the oc currence of GERD(P

用秩和比法对37例脑瘫患者施行SPR术中影响应激反应的诸因素进行分析。结果显示：3—6岁小儿、切断后根小束大于50％者、电刺激量平均为5．1—10mA者、芬太尼量大于3μg／kg·h者和于腰骶部行SPR者应激反应最强。3、4级痉挛者、芬太尼量为2．1—3μg／kg·h者、7—13岁儿童、切断后根小束41—50％者和电刺激量平均大于10mA者应激反应较强。5级痉挛、14岁以上青成年和电刺激量平均小于5mA者，应激反应较弱。而芬太尼量小于2μg／kg·h、切断后根小束少于40％和行颈胸段SPR者应激反应最弱。经临床分析，作者提出：SPR中应特别注意6岁前小儿及切断后根小束超过50％的脑瘫患者的应激反应。

Objective To investigate the correlation between expression of vascular endothelial growth factor(VEGF) of serum and tumor tissues and the clinical prognosis in patients with breast cancer. Methods The expressions of VEGF level of serum and tumor tissues in 44 patients with invasive duct breast cancer, 13 with benign breast diseases and 40 healthy controls. Serum VEGF level was measured by ELISA method. The protein expression of tissue VEGF, ER and C-erbB-2 were evaluated by immunohistochemistry LSAB method. Results Serum VEGF level and tissue VEGF expression in breast cancer were higher than those in benign breast diseases (P0.05). VEGF expression was correlated with lymph node metastasis (P 0.05). Conclusion There is positively correlation between serum VEGF level and tissue VEGF expression, and between VEGF expression and clinic prognosis. Serum VEGF level may be one of important index of prognosis estimation in patients with breast cancer.

Child, Preschool ; Humans ; Hypertension, Portal ; physiopathology ; Male

Coloboma ; Humans ; Infant, Newborn ; Male ; Optic Nerve ; abnormalities