1.Spontaneous regression of tumors.
Chinese Journal of Pathology 2009;38(9):642-646
2.Cat scrach disease.
Chinese Journal of Pathology 2004;33(5):475-477
3.Retrospective analysis of craniofacial features in patients with cleidocranial dysplasia
Hong CHEN ; Meng QIN ; Haining JI ; Yuanhua ZHENG ; Yin DING
Journal of Practical Stomatology 2015;(3):407-411
Objective:To investigate the craniofacial features in patients with cleidocranial dysplasia (CCD).Methods:The facial features,cervical vertebral bone age and skeletal abnormalities of 8 patients with CCD were studied by analyzing facial photos,cephalo-metric and panoramic radiographs.Results:4 patients were in the early growth stage and the other 4 in the late period of development. The bossing forehead and inclined eye fissure were observed in all patients,but underdevelopment of midfaces were not obviously pres-ented in younger patients.Morphological abnormalities of craniofacial bones,such as ascending ramus,coronoid process,nasal bones and disappearence of gonial angle were observed in all patients.Conclusion:Some craniofacial malformations in patients with CCD may be presented earlier than underdeveloped midface,which can be helpful for early diagnosis of CCD.
4.Content Determination of Related Substances in Alprostadil for Injection by HPLC
Rui DING ; Hong JI ; Si CHEN ; Yiming LIU ; Li YU
China Pharmacy 2007;0(29):-
OBJECTIVE: To establish an HPLC method for the content determination of prostaglandin A1 and prostaglandin B1 in Alprostadil for injection.METHODS: The determination was performed on Alltech Alltima C18 column with mobile phase consisted of phosphate puffer(pH=6.3)-acetonitrile-methanol(70 ∶ 25 ∶ 5) at a flow rate of 1.5 mL? min-1.The detection wavelength was set at 196 nm.The column temperature was set at room temperature and the injection volume was 20 ?L.RESULTS: The prostaglandin A1 and prostaglandin B1 were well separated from main component and other impurities.The linear range of prostaglandin A1 and prostaglandin B1 were 0.175~19.00 ?g?mL-1(r=0.999 7) and 0.23~19.90 ?g?mL-1(r=0.999 2).The contents of prostaglandin A1 in 3 batches of samples were 4.7%,4.9% and 4.3%,and the contents of prostaglandin B1 in 3 batches of samples were 0.6%,0.8% and 0.5% respectively.CONCLUSIONS: This method is proved to be simple,specific and suitable for the content determination of related substances in Alprostadil for injection.
5.Comparison of enhancement features of primary hepatocellular carcinoma and recurrent hepatocelluar carcinoma on contrast-enhanced ultrasonography
Ruixue WEI ; Wenping WANG ; Hong DING ; Beijian HUANG ; Chaolun LI ; Hong HAN ; Zhengbiao JI
Chinese Journal of Ultrasonography 2010;19(9):773-775
Objective To compare enhancement features of primary hepatocellular carcinoma(PHCC)and recurrent hepatocellular carcinoma(RHCC) on.contrast-enhanced ultrasonography(CEUS). Methods CEUS was performed in 56 patients with 70 RHCC and 83 patients with 93 PHCC. The enhancement features of these two groups of hepatocellular carcinoma were compared. The time used for the enhancement material to arrive the lesion(Ta ), that used for the lesion to become isoechoic(T1 ) and hypoechoic relative to the surrounding hepatic parenchyma(To) were analyzed. The echogenicity change between the lesion and the parenchyma was observed during arterial phase,portal phase and delayed phase. Results The time used for the lesion to become hypoechogenicity of RHCC and PHCC was (104.0 ± 51.8)s, (85.5 ± 43.0)srespectively,there was significant difference between the two groups( P = 0.010). There were 24 (34.3 % )cases of RHCC and 16 ( 17.2% ) cases of PHCC becoming isoechoic during portal phase,the former rate was significantly higher than the later one( P = 0. 012). Conclusions There is significant difference between PHCC and RHCC in the performance of CEUS,this is useful for the early diagnosis of RHCC.
6.Analysis of the hemodynamic changes of transplanted liver with acute rejection using color Doppler flow imaging: a preliminary study
Hong HAN ; Wenping WANG ; Shaohua CHEN ; Zhengbiao JI ; Hong DING ; Hui ZHANG ; Jiexian WEN
Chinese Journal of Ultrasonography 2013;(6):496-499
Objective To investigate the viability of analysis of hemodynamic changes with color Doppler flow imaging in the prediction of acute rejection in transplanted liver.Methods Sixty-eight patients enrolled in the study were categorized into three groups:transplanted liver without acute rejection [rejection activity index(RAI) 0-3,n =24],transplanted liver with mild acute rejection (RAI 4-5,n =23),transplanted liver with moderate and severe acute rejection (RAI 6-9,n =21).All the patients were confirmed by pathology.The color Doppler flow imaging were performed in all the patients within 24 hours and 1 week after biopsy.Results In transplanted liver with moderate and severe acute rejection,the peak systolic velocity of portal vein (PV-PSV) was (31.4 ± 14.1)cm/s,significantly lower than that in transplanted liver without acute rejection,which was (45.1 ± 17.7)cm/s (P <0.05).A week later after steroid therapy,the PV-PSV in transplanted liver with moderate and severe rejection was increased to (46.7 ± 21.8)cm/s(P <0.05).Patients with acute rejection were associated with the decrease of the PVPSV (P <0.05).Conclusions The decrease of PV-PSV may have some clinical value in evaluation the acute rejection in transplanted liver.
7.Predicting acute rejection in transplanted liver with virtul touch tissue quantification technique: a preliminary study
Hong HAN ; Zhengbiao JI ; Hong DING ; Hui ZHANG ; Wenping WANG ; Ruixue WEI
Chinese Journal of Ultrasonography 2012;21(5):390-393
Objective To investigate the viability of virtual touch tissue quantification (VTQ)technique in the prediction of acute rejection in transplanted liver.Methods One hundred and eighteen patients enrolled in the study were categorized into four groups:normal control (n =31),cirrhosis ( n =29),transplanted liver with acute rejection (n =28),transplant liver without any complications (n =30).All the patients were confirmed by pathology or clinical results.The VTQ of right robe of liver was obtained by a ultrasound system with VTQ technique and the data was compared among the four groups.Results The VTQ was (1.10 ± 0.29)m/s,(1.33 ± 0.33) m/s,(1.81 ± 0.47) m/s and (2.12 ± 0.59) m/s in normal control,transplanted liver without any complications,transplanted liver with acute rejection and cirrhosis group,respectively.It was significantly different in all four groups (P<0.01).Patients with acute rejection were associated with the increase of the VTQ values (P<0.01).Using a cutoff of VTQ>1.36 m/s measured in the transplanted liver for prediction of acute rejection,the sensitivity and specificity were 82.1% and 68.2%.Conclusions VTQ technique may have some clinical value in evaluation the acute rejection in transplanted liver.
8.Epithelioid angiosarcoma after radical mastectomy for breast carcinoma: a case report.
Hong-ji DING ; Guo-guang WEI ; Li-qun YU ; Qi-song WU ; Yan-guang DONG
Chinese Journal of Pathology 2006;35(10):637-638
Aged
;
Antigens, CD34
;
metabolism
;
Breast Neoplasms
;
metabolism
;
pathology
;
therapy
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Chemotherapy, Adjuvant
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Combined Modality Therapy
;
Epithelioid Cells
;
pathology
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Female
;
Follow-Up Studies
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Hemangiosarcoma
;
metabolism
;
pathology
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Humans
;
Immunohistochemistry
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Mastectomy, Radical
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Neoplasms, Second Primary
;
metabolism
;
pathology
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Radiotherapy, Adjuvant
;
Vimentin
;
metabolism
9.Calcinosis cutis of bilateral knees: report of a case.
Hong-ji DING ; Chun-yan LIU ; Zhi-qiang LIU ; Jing LI ; Chuan-sen ZHANG
Chinese Journal of Pathology 2012;41(12):852-853
Calcinosis
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pathology
;
surgery
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Child
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Diagnosis, Differential
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Humans
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Knee
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Male
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Skin Diseases
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pathology
;
surgery
10.Quantitative analysis of contrast-enhanced ultrasonography on hepatocellular carcinoma: Correlation with tumor differentiated grades
Peili FAN ; Hong DING ; Jiakai GUO ; Xiyuan LIN ; Yuan JI ; Huichuan SUN ; Wenping WANG
Chinese Journal of Medical Imaging Technology 2009;25(12):2243-2245
Objective To investigate the relationship between hemodynamic parameters from quantitative analysis of contrast-enhanced ultrasonography (CEUS) on hepatocellular carcinoma (HCC) and pathological tumor differentiated grades. Methods Seventy-seven HCC lesions were examinated and off-line analyzed with dynamic images. Quantitative parameters such as slope of decrease to half of peak (SD), increased signal intensity (ISI), area under the curve (AUC) and blood flow coefficient (BF) were acquired, and the standardized values (sISI, sAUC and sBF) included the ratio of parameters from tumor to those from hepatic parenchyma. These quantitative parameters were correlated with tumor grades according to Edmonson criteria. Results There was significant difference (P<0.05) of SD, AUC and BF, as well as standardized values (sISI, sAUC and sBF) between different grades of HCC. AUC, BF, sISI, sAUC and sBF were negative correlated with differentiated grades, respectively (P<0.05). Well-differentiated HCC had significantly higher perfusion values than HCC of other grades (P<0.05). Conclusion Quantitative analysis of CEUS can assess differentiation of HCC indirectly, and might reveal biological behavior of malignant tumors.