1.Transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy
Liuping YANG ; Hong ZHONG ; Junhong DENG
Chinese Journal of Ultrasonography 1993;0(01):-
Objective To evaluate the safety and efficacy of transrectal ultrasound guided prostatic nerve blockade for pain control during transrectal prostate biopsy.Methods Seventy-three patients requiring systematic 13 cores biopsy of the prostate were randomized into two groups.Group A(37 cases) received an injection of 5 ml 1% lidocaine into the prostatic neurovascular bundles on each side at the base of the prostate under ultrasound guidance,and group B(36 cases) received 5 ml saline ( 0.9% sodium chloride) at the same way.Pain during biopsy was assessed using a 10-point linear visual analog pain scale immediately after this procedure.Results The mean pain scores during transrectal prostate biopsy were significantly lower in group A than that in group B( 1.1? 0.6 vs 5.9? 3.1,t= 4.81,P
2.Transrectal ultrasound guided systematic 13 cores prostate biopsy for diagnosing prostate carcinoma:report of 160 cases
Jianbo HU ; Liuping YANG ; Hong ZHONG
Chinese Journal of Urology 1994;0(02):-
Objective To evaluate the clinical value of transrectal ultrasound guided systematic 13 cores prostate biopsy. Methods A total of 160 patients referred for abnormal digital rectal examination and (or) prostate specific antigen 4ng/ml or greater underwent transrectal ultrasound guided systematic 13 cores prostate biopsy.That was,in addition to the standard sextant biopsies,cores were taken from the far lateral and middle regions of the gland as described by Eskew.Pathological findings of the additional regions were compared with those of the sextant regions. Results Of the patients 35 % had cancer on biopsy(56 /160).Of the 56 patients with prostate cancer 12(21%)had carcinoma only in the additional regions,which would be undetected on the sextant biopsy technique (P
3.Drinking Water Quality and Intestinal Infectious Diseases in Urban and Rural Boarding Schools in Guangxi
Zhenzhu TANG ; Gemei ZHONG ; Hong YANG
Journal of Environment and Health 1993;0(01):-
Objective To know the drinking water safety for students and teachers in urban and rural boarding schools in Guangxi, further to prevent and control the water-borne diseases. Methods The random stratified cluster sampling method was used to select 100 schools in 10 counties of Nanning, Liuzhou and Guilin cities. The drinking water samples were collected and tested according to Sanitary Standard for Drinking Water Quality2001. The epidemic situation of intestinal infectious diseases was investigated. Results The total qualified rate of drinking water quality in 100 boarding schools of 10 counties cities was only 27.00%, as for the water supply provided for themselves with disinfection, the qualified rate was 47.37%, without disinfection, it was 16.95%. 24 outbreak events of intestinal infectious diseases occured in 100 boarding schools in 2000-2005, 2 339 of school teachers and students were attacked, including 13 outbreak events of typhoid and paratyphoid 54.17% with 1 280 cases 54.72%, 6 outbreak events of bacterial dysentery25.00% with 829 cases35.44%, 4 outbreak events of infectious diarrhea 16.67% with 225 cases 9.62%, 1 outbreak of hepatitis A 4.17% with 5 cases 0.21%. These 24 epidemic events were caused by drinking water, the morbidity was higher in the schools where there was no disinfection facility in water supply. Conclusion Some of water supply for some urban and rural boarding schools have been polluted with bacteria in Guangxi, so drinking water disinfection should be done to ensure water safety and prevent the related diseases in these schools.
4.Etiology of severe acute respiratory syndrome.
Chang-an ZHAO ; Zhong-zhi LI ; Yong-hong YANG
Chinese Journal of Pediatrics 2003;41(6):439-440
6.Clinical analysis of 12 lymphoplasmacytic lymphoma cases.
Hong-liang YANG ; Yi-zhuo ZHANG ; Zhong-li ZHAN
Chinese Journal of Hematology 2012;33(4):336-339
Aged
;
Biopsy
;
Bone Marrow Examination
;
Female
;
Humans
;
Lymph Nodes
;
pathology
;
Lymphoma, B-Cell
;
diagnosis
;
pathology
;
Male
;
Middle Aged
;
Retrospective Studies
;
Young Adult
7.Meta-analysis of phacoemulsification versus phacotrabeculectomy for primary angle closure glaucoma with cataract
Hong-yang, ZHANG ; Min-bin, YU ; Zhong-jun, DUN
Chinese Journal of Experimental Ophthalmology 2013;(3):270-274
Background Increase of lens thickness at incipient cataract is a key factor of onset of primary angle-closure glaucoma (PACG).Phacoemulsification (Phaco) or phacotrabeculectomy (Phacotrabe) have been documented to be effective for the patients of PACG associated with cataract.However,which surgery is more effective and safe is lack of evidence.Objective This study was to assess and compare the clinical effectiveness of Phaco versus Phacotrabe for PACG with cataract.Methods The relevant literature was searched electronically from the PubMed (1966 to June 2011),EMB Reviews (1966 to June 2011) and Cochrane Library (Issue 1,2011).The manually searching of relevant conference proceedings was used as the supplement.The articles of randomized controlled trial (RCT) about the clinical effectiveness of Phaco versus Phacotrabe for PACG with cataract were included.The methodology quality of included literature was graded.The analysis indexes included intraocular pressure (IOP)-lowing range,postoperative administration of glaucoma drugs,incidence of positive complication,postoperative best corrective visual acuity (BCVA) and perimetry damage.The RevMan4.2 software from Cochrane Collaboration was used for the Meta analyses.Results Three RCTs about phaco versus Phacotrabe for PACG with cataract were selected in this study with the 164 eyes of 164 cases.Meta analysis showed that the IOP-lowing range was larger in the Phacotrabe group compared to only Phaco group with the WMD of 1.17 and 95% CI of 0.06-2.27 (P =0.040),and the drug dosage of anti-glaucoma was less in the Phacotrabe group in comparison with the Phaco group with the WMD of 0.5 and 95% CI of 0.24-0.77 (P =0.000).However,the incidence of postoperative complication was higher in the Phacotrabe group than that of the Phaco group with the RR of 0.08 and 95% CI of 0.02-0.33 (P =0.000).No significant difference was found in the BCVA (WMD =0,95% CI:-0.13-0.13,P=1.00) andperimetry (WMD =1.01,95%CI:0.56-1.82,P=0.98).Conclusions Compared with Phaco,Phacotrab has a better IOP-lowing effectiveness and slightly worse safety.Phaco and Phacotrab have a fairly influencc in the postoperative BCVA and perimetry.As the sample sizes of the included trials are relatively small,more welldesigned large-scale RCTs are needed.
8.Early use of nutritional support in patients after liver transplantation
Wenxin YANG ; Zhengjiang ZHONG ; Hong SHEN ; Xiaomei CHENG ; Jianxin MA
Parenteral & Enteral Nutrition 1997;0(04):-
Objective: To discuss the way of early nutritional support in the patients after the liver transplantation. Methods: The nutritional support was used in 28 patients who had suffered the orthopetic liver transplantation (OLT).Parenteral nutrition was started as soon as possible after the operation. On the fourth day after the operation, enteral nutrition was also used. Results: 5 patients died from the postoperative complications. 23 patients survived and had been in better nutrition. Conclusion: The early nutrition support can play an important role in the patients recovery after OLT. EN should be administrated immediately when the gut functions.
9.Treatment of Displaced Intra-articular Calcaneal Fractures by Minimally Invasive Retractor Reduction and Fixation Through Sinus Tarsi Approach Together with External Application of Chinese Medicine
Boyuan SU ; Yongxiong PAN ; Jingsong HONG ; Zhandong SUN ; Zhong YANG
Journal of Guangzhou University of Traditional Chinese Medicine 2015;32(6):1022-1026
Objective To evaluate the therapeutic effect of minimally invasive retractor reduction and fixation through sinus tarsi approach together with external application of Chinese medicine for displaced intra-articular calcaneal fractures. Methods From October of 2009 to June of 2013, 52 patients with displaced intra-articular calcaneal fractures (Sanders type Ⅱ, Ⅲ) were enrolled into the study. The patients received minimally invasive retractor reduction through sinus tarsi approach and fixation with small plate and cannulated screws, and after the operation were given external washing with Chinese herbal formula Shenxing Fang ( mainly composed of Herba Lycopodii, Herba Speranskiae Tuberculatae, Rhizoma Sparganii, Rhizoma Curcumae, Herba Asari, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparat). Follow-up was carried out for the evaluation of the therapeutic effect of displaced intra-articular calcaneal fractures ( Sanders type Ⅱ, Ⅲ). Results Forty cases (involving 44 feet) received the postoperative follow-up for 12-18 months (average being 14.2 months). The Maryland foot scores were 95 points for type Ⅱ displaced intra-articular calcaneal fractures, and 86 points for type Ⅲ fractures. Satisfactory results were achieved in the height, width and length of the calcaneus as well as the B?hler's and Gissane angle ( P<0.01). Conclusion Minimally invasive retracter reduction and fixation through sinus tarsi approach together with external application of Chinese medicine exert satisfying effect for the treatment of displaced intra-articular calcaneal fractures.
10.Effects of combination of glycyrrhizin acid, ligustrazine and puerarin on LPS-induced cytokines expression in macrophage.
Zhao LIU ; Ju-ying ZHONG ; Er-ning GAO ; Hong YANG
China Journal of Chinese Materia Medica 2015;40(20):4068-4074
To study the anti-inflammatory activity of glycyrrhizin acid, ligustrazine and puerarin. In the study, the liquichip-based high-throughput synchronous detection technique for 23 inflammatory factors, uniform design, comprehensive weight method were adopted to study the effect of different combined administration of glycyrrhizin acid, ligustrazine and puerarin in inhibiting the expression of lipopolysaccharide (LPS)-induced RAW264. 7 cells and multiple inflammatory cytokines. In the study, the uniform design table U₉ (9³) was adopted to design doses of glycyrrhizin acid, ligustrazine and puerarin. The liquichip technique was used to detect the effect of different combined administration of glycyrrhizin acid, ligustrazine and puerarin on the 23 cytokines expressed in LPS-induced mouse macrophage RAW264. 7 inflammation model. The traditional Chinese medicine component optimization software and the improved least angle regression algorithm were used to analyze the dose-effect relationship among the three components and the cytokine inhibition rate and produce the regression equation. The comprehensive weight method was applied to get the optimal dose ratio of glycyrrhizic acid, ligustrazine and puerarin with highest efficacy of 25:2:13 and verify the optimal dose ratio. The verification results were consistent with the prediction trend, indicating the accuracy of the mathematical model for predicting the experiment. The experimental results showed the multi-target and multi-level efficacies of glycyrrhizic acid, ligustrazine and puerarin and the high anti-inflammatory activity of their combined administration, which provides powerful basis for subsequent drug development.
Animals
;
Anti-Inflammatory Agents
;
pharmacology
;
Cytokines
;
Glycyrrhizic Acid
;
pharmacology
;
Isoflavones
;
pharmacology
;
Lipopolysaccharides
;
immunology
;
Macrophages
;
drug effects
;
immunology
;
Mice
;
NF-kappa B
;
genetics
;
immunology
;
Pyrazines
;
pharmacology
;
RAW 264.7 Cells