1.Experimental study on treatment of simple obesity with acupuncture
Qunli WEI ; Junhao GUO ; Hong BAI
Journal of Medical Postgraduates 2001;14(3):217-220
Objectives: Observe the effects of acupuncture on obese SD rats fed by self-prescribed high calorie diet. Methods: The model group were male SD rats fed by self-prescribed high calorie diet, while the control group were male SD rats fed by common roughage. After acupuncture, the changes of some indexes were observed such as eating and drinking amount,body weight,length, Lee index,fattiness in groin and circumrenal areas, TG,TC,BG levels in blood etc. Results: The obesity was defined as the average body weight of the model group was 20% heavier than the average body weight in the control group. And the obesity ratio was 56%. The indexes were changed in different degrees with statistic significance after one period of treatment. Conclusions: Over-nutrition is one of the causes of obesity. Our high calorie feed for obese rat is reasonable. Acupuncture has obvious therapeutic effects for simple obesity.
2.The influence of continuous blood purification on the intra -abdominal pressure and the gastrointestinal ;dysfunction of intra-abdominal hypertension
Jingen BAI ; Yunbiao WEI ; Hong LI
Chinese Journal of Primary Medicine and Pharmacy 2017;24(2):290-293
Objective To study the influence of continuous blood purification(CBP)on the intra-abdomi-nal pressure (IAP ) and the gastrointestinal dysfunction of intra -abdominal hypertension (IAH ).Methods 80 patients with IAH were selected and divided into observation group and control group(n=40)according to random number table method.The observation group was given 3d CBP therapy.The control group was given conventional treatment.The mean arterial pressure (MAP ),IAP and abdominal perfusion pressure (APP ) were detected.The number of gastrointestinal symptoms was observed,sequential organ failure score(SOFA score)was used to assess the organ function of the two groups before and after treatment.Results The MAP,IAP,APP,SOFA score of the two groups before treatment had no statistically significant differences(P>0.05).The MAP of the two groups after treat-ment[(88.46 ±8.93)mmHg vs.(87.76 ±8.04)mmHg]had no statistically significant difference(P>0.05).The IAP[(9.02 ±1.06)mmHg]and SOFA score[(1.32 ±0.45)]of the observation group after treatment were signifi-cantly lower,the APP [(85.34 ±7.59)mmHg]was obviously higher than before treatment and the control group [(19.54 ±4.23)mmHg,(5.24 ±2.05)points,(70.76 ±6.43)mmHg],the differences were statistically significant (t=3.575,2.855,3.274,3.563,3.114,3.782,all P<0.05).Before treatment,the number of the gastrointestinal symptoms of the two groups[(44.56 ±8.53)times vs.(45.32 ±8.21)times]had no statistically significant difference (P>0.05).The number of gastrointestinal symptoms of the observation group after treatment [(6.54 ±2.24)times] was obviously lower than before treatment and the control group [(15.45 ±4.43)times],the difference was statisti-cally significant(t =3.022,P<0.05 ).The 30 d and 60 d survival rates of the observation group were 87.5%(35/40)and 65%(26/40),which of the control group were 80.0%(32/40)and 55%(22/40),although which of the observation group were higher than the control group,but there were no statistically significant differences(P>0.05 ).Conclusion CBP could significantly reduce the IPA of the patients with IAH,raise the APP,improve gastro-intestinal perfusion,reduce gastrointestinal symptoms,has positive significance to improve the gastrointestinal dysfunction.
3.STUDY ON LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN-1 IN RENAL ISCHEMIA-REPERFUSION INJURY IN RATS
Wei HONG ; Hongwei BAI ; Bingyi SHI
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
To investigate the change in renal CD11a and myeloperoxidase (MPO) contents and renal function during ischemia-reperfusion injury (IRI) of rat kidney, as well as the role of lymphocyte function associated antigen-1 (LFA-1) played in renal IRI, we utilized a rat model of renal IRI to detect the renal tissue contents of CDlla and MPO and renal functioa The results showed that the levels of CD11a and MPO were very low in normal renal tissue, but increased significantly in ischemia reperfusion. Renal failure was presented in rats with IRI. The levels in the ischemia-60min-reperfusion group were higher than those in the ischemia-30min-reperfusion group in the same time points. Our conclusion is the levels of CD11a and MPO in rat renal tissue increase significantly during renal IRI. LFA-1-mediated leukocyte adherence plays an important role in renal IRI. Up-regulation of CDlla further elucidates the mechanism of relation between IRI and acute rejection: more heavier IRI is, more possible acute rejection would be.
4.Preliminary research of sound velocity tissue quantification on liver fibrosis stage
Qian WANG ; Hong AI ; Xixi ZHANG ; Wei WEI ; Yunfei BAI
Chinese Journal of Ultrasonography 2016;(1):29-35
Objective To evaluate sound velocity tissue quantification ( SVQ ) for the quantitative assessment of liver fibrosis stage in chronic hepatitis B ,and to evaluate the correlation between diagnostic performance of sound velocity tissue quantification and blood parameters . Methods From the May of 2013 to May of 2014 ,collect ninety‐nine patients with chronic hepatitis B who was diagnosed by clinic and / or liver biopsy as experiment group ,and thirty healthy volunteers as control group at the same time . The experiment group and control group were evaluated with to measurement the zone speed index ( ZSI) ,and blood cell count . The AST/PLT ratio index ( APRI) was calculated according the following formula , APRI=AST(ULN)/PLT(109/L) . The liver biopsy was performed in the same day with SVQ and all blood parameters .ZSI and APRI were compared by correlation with liver fibrosis stage in chronic hepatitis B . Referring to the histologic fibrosis stage on liver biopsy ,all the ZSI and the APRI value were assessed by using ROC curve analysis . The corresponding cut‐off value ,sensitivity and specificity were also calculated andcompared.Results 1)ThemeanvaluesofAPRIwere(15.9±5.7)m/sforpatientswithS0,(28.1± 2 .8)m/s for patients with S1 ,(35 .8 ± 1 .2)m/s for patients with S2 ,(42 .6 ± 0 .8)m/s for patients with S3 , and (46 .3 ± 1 .3)m/s for patients with S4 .2)Accordingly ,the areas under the ROC curve for ZSI and APRI were 0 .875 and 0 .762 for S≥S1 ,0 .832 and 0 .597 for S≥S2 ,0 .913 and 0 .675 for S≥S3 ,0 .891 and 0 .709 for S≥S4 ,respectively . Conclusions The ZSI and APRI all could be used to evaluate the stage of liver fibrosis ,but the ZSI index is superior to APRI in assessing the stage of liver fibrosis . SVQ could provide object and accurate image ,the quantitative analysis of tissue could timely and accurately evaluate the severity of liver fibrosis .
5.Celomic and retroperitoneal lipoleiomyosarcoma: report of a case.
Xiu-zhen LI ; Hong-quan WEI ; Bai-zhou LI
Chinese Journal of Pathology 2011;40(5):343-344
Abdominal Neoplasms
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metabolism
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pathology
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surgery
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Actins
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metabolism
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Angiomyolipoma
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metabolism
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pathology
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Desmin
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metabolism
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Diagnosis, Differential
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Humans
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Leiomyosarcoma
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metabolism
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pathology
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surgery
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Liposarcoma
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metabolism
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pathology
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surgery
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Male
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Middle Aged
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Neoplasms, Multiple Primary
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metabolism
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pathology
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surgery
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Retroperitoneal Neoplasms
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metabolism
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pathology
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surgery
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S100 Proteins
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metabolism
6.STUDY ON SUPEROXIDE ANION RADICAL SCAVENGING ACTIVITY OF SELENO-SULFUR-CONTAINING AMINO ACID
Yan BAI ; Biyin QIN ; Ying LIU ; Wei HONG ; Yanfen ZHOU
Acta Nutrimenta Sinica 1956;0(01):-
selenomethionine.Although the structure of selenomethionine and methionine are similar,the electron supply ability of selenomethionine is lower than that of methionine.Conclusion Methionine as electrons provider could accelerate the photolysis of VB2 to generate ?O 2,but selenocystine,selenomethionine and cystine could directily scavenge ?O 2 generated by VB2.
7.Steroid Withdrawal in Liver Transplantation
jia-bin, JIN ; cheng-hong, PENG ; bai-yong, SHEN ; hong-wei, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(06):-
Recently a great number of new immunodepressants have emerged due to the side effects of steroids.Therefore,relatively more perfect steroid withdrawl regimens have been studied by many researchers at home and abroad.This article reviews the course of steroid withdrawal in liver transplantation,introduces and compares different protocols of steroid withdrawal.
8.Advances in cell components of bioartificial liver
bao-san, HAN ; bai-yong, SHEN ; cheng-hong, PENG ; hong-wei, LI
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(07):-
The biological artificial liver(BAL) can offer reliable artificial liver support for the patients with hepatic failure.All BAL devices contain hepatocytes as their biological component,whose specific biological characteristics contribute to the function of the BAL.During the past two decades,various cells including human hepatocytes,heterogeneous hepatocytes and liver cell lines have been used and different culture methods have been studied to optimize the activity of the biological component.However,both functionality and safety of these cells should be improved before successful use in BAL. This paper summarizes the latest progress on it.
9.Study on mutations of gyrA gene of tuberculosis quinolone-tolerant isolates in coal workers' pneumoconiosis.
Ping JIANG ; Guo-yang WANG ; Bai FENG ; Wei WANG ; Hong-min LI ; Fang ZHANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2006;24(2):124-125
Aged
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Aged, 80 and over
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Antibiotics, Antitubercular
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pharmacology
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Coal Mining
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DNA Gyrase
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genetics
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Drug Resistance, Bacterial
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genetics
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Humans
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Male
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Middle Aged
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Mutation
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Mycobacterium tuberculosis
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drug effects
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genetics
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Pneumoconiosis
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complications
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Polymerase Chain Reaction
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Polymorphism, Single-Stranded Conformational
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Quinolones
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pharmacology
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Tuberculosis, Pulmonary
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complications
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microbiology
10.Recognition of depression and related risk factors among non psychiatric doctors in tertiary general hospital outpatients in Beijing
Ronghuan JIANG ; Weimin DANG ; Hong MA ; Meiyan LIU ; Wenpei BAI ; Jing WEI ; Yanling HE
Chinese Journal of Internal Medicine 2010;49(6):477-479
0bjective To explore the level of identification and related factors of depression in physicians of Beijing tertiary general hospitals.Methods A cross-sectional investigation was used to screen the outpatients,and depression was diagnosed according to Mini International Neuropsyehiatric Interview (MINI).Identification of depression was defined as referral to psychiatrist or managed with antidepressant or sedative hypnotics.Results Among 248 cases of depression,30(12.1%)were referred to psychiatrists,28(8.9%)managed with antidepressant or sedative hypnotics.The identification rate of depression by physicians was 21.0%.and the identification rate by neurologist was 40.4%,which is higher than the rate by cardiologist(22.4%),gastrointestinal physician(3.8%)and gynecologist(2.0%)(χ2=61.077,P<0.05).Visiting neurology department,severity of life impairment,with psychotic distress history,hadpsychological complaints.co-morbidity with anxiety related to the physician's identification of depression.Among the psychological complaints.only mood disorder and insomnia were related to the physician'sidentification of depression.Conclusions The level of depression identification by physician was low,the level of neurologist wag higher than that of cardiologist,gastrointestinal physician and gynecologist.The patient with serious life impairment,psychotic distress history,mood disorder and insomnia complaints was asily to be identified.