Objective To explore the influence of combined warming measure on intraoperative temperature and coagulation function in patients during gynecologic laparoscopic surgery. Methods A total of 70 patients undergoing gynecologic laparoscopic surgery were randomly divided into the intervention group ( n =35 ) and the control group ( n = 35 ). The intervention group received combined warming measure including using inflatable warming blanket, beating transfusion and rinses, while the regular nursing was performed in the control group. The core body temperature of the patients were recorded before operation, 1 hour after the beginning of operation and at the completion of operation. The amounts of blood loss were recorded as well. The index of coagulation function before and after operation were detected. Results Compared with the intervention group, the core body temperature 1 hour after the beginning of operation and at the completion of operation were lower; the amounts of blood loss were larger; the thrombin time prolonged; the fibrinogen and peripheral blood platelets were lower in the control group. There were statistical meanings in all of the defferences ( P < 0. 05 ).Conclusions Combined warming measure can effectively prevent intraoperative hypothermia, improve the coagulation function disorders and reduce the amounts of blood loss. The method can be used in clinic widely.