Acquired Immunodeficiency Syndrome ; diagnosis ; diagnostic imaging ; China ; Humans ; Radiography ; Radiology ; methods

With the progress of society and development of sexual medicine, the therapeutic effects of female sexual dysfunction (FSD) have been improved increasingly. This review summarizes the basic therapeutic approaches to FSD, including psychotherapy, sexual behavior therapy, mechanical skills, life style adjustment, physical exercise, acupuncture, medication, surgery, and gene therapy. It also points out the objective understanding of the limitations of the available therapeutic methods, with stress on patient-oriented comprehensive therapeutic principles and increased attention to recognition education among the patients so as to improve the present status of FSD treatment.
Female ; Humans ; Sexual Dysfunction, Physiological ; therapy

Objective To investigate the effects of rocuronium on the neuromuscular junction of rat diaphragm. Methods One hundred and sixty rats were used in the study which was approved by the Animal Care Committee of the General Hospital of PLA. In isolated non-uniformly stretched muscle preparation (INSMP) of rat diaphragm, micro-endplate potentials (MEPP) and endplate potentials (EPP) were recorded simultaneously with one microelectrode of one endplate. The effects of rocuronium in dosages of 2.5, 5, 10, 20?g/ml on the amplitude and frequency of MEPP and the amplitude of EPP were observed. Results Rocuronium could decrease both the amplitude and frequency of MEPP obviously and the onset time was 1min after drug administration. The amplitude of EPP was depressed by rocuronium in a dose of 5?g/ml at 3min. Neither 2.5?g/ml nor 0.5?g/ml of rocuronium produced any effect on the amplitude of EPP. Conclusion The results indicated that rocuronium might produce a rapid and early presynaptic effect on neuromuscular junction in INSMP in rats.

Objective: To evaluate the efficacy and safety for the application of low-dose vitamin K antagonist (VKA) during whole pregnancy and low-molecular-weight heparin/heparin at early pregnancy in patients after mechanical heart valve replacement. Methods: We searched the Cochrane library (2016 Issue 2), PubMed, EMbase, CBM, Tsinghua Tongfang (CNKI), Wanfang and VIP databases to collect the literatures for the application of low-dose VKA during whole pregnancy and low-molecular-weight heparin/heparin at early pregnancy up to 2016-06. The literatures were independently screened by 2 reviewers and Meta-analysis was performed using RevMan 5.3 software. Results: 12 studies were finally enrolled. Meta-analysis presented that compared with the application of low-molecular-weight heparin/heparin at early pregnancy, low-dose VKA during whole pregnancy showed decreased valvular thrombosis rate (OR=0.26, 95% CI 0.13-0.54, P<0.001), lower spontaneous abortion rate (OR=1.99, 95% CI 1.21-3.26, P=0.006) and increased fetal abnormality rate (OR=3.39, 95% CI 1.11-10.37, P=0.03); while the maternal mortality (OR=0.79, 95% CI 0.24-2.58, P=0.70), peri-natal bleeding rate (OR=0.56, 95% CI 0.27-1.18, P=0.13) and the incidence of stillbirth (OR=1.80, 95% CI 0.94-3.44, P=0.07) were similar between two conditions. Conclusion: Current evidence indicated that the application of low-doseVKA during whole pregnancy decreased the rates of valvular thrombosis and spontaneous abortion in patients after mechanical heart valve replacement, while increased the rate of fetal abnormality. Further investigation is needed to confirm the above conclusion.

Adolescent ; Adult ; Female ; Histiocytic Necrotizing Lymphadenitis ; diagnosis ; therapy ; Humans ; Lymph Nodes ; Male ; Middle Aged ; Neck ; Young Adult

By direct communication between clinicians and laboratorians, obstacles between clinical work and laboratory diagnosis were unequivocally found at an academic conference. Many clinical physicians feel disappointed and frustrated at the laboratory diagnosis by semen analysis and frankly express their expectations, as to recognize the role and significance of laboratory diagnosis, understand the value of routine semen analysis, work out the puzzles in the analysis of sperm morphology, fulfil the requirements for the identification of cells in semen, and obtain responses from and initiate discussions among laboratorians about the relevant questions. Both laboratorians and clinicians are appealing for strengthened management and earlier establishment of national standards and operating specifications for laboratory diagnosis by semen analysis.
Clinical Laboratory Techniques ; Communication ; Humans ; Interprofessional Relations ; Male ; Physicians ; Semen ; Semen Analysis

Animals ; Danazol ; pharmacology ; Endometriosis ; drug therapy ; Endometrium ; drug effects ; Female ; Interleukin-6 ; metabolism ; RNA, Messenger ; genetics ; Rats ; Rats, Sprague-Dawley

Acupuncture Therapy ; Adult ; Aged ; Bloodletting ; Combined Modality Therapy ; Crying ; Female ; Humans ; Laughter ; Male ; Middle Aged ; Stroke ; psychology ; therapy ; Treatment Outcome

AIM: To evaluate the relationship between axial length ( AL ) , corneal and lens refractive power, and the refractive error in children.
METHODS:Totally 44 children 88 eyes with refractive error who underwent retinoscopy with cycloplegia, to be measured spherical equivalent refractive error. Axial length was measured by a noncontact optical biometry ( ZEISS IOL-Master) , and corneal K and anterior chamber depth ( ACD) were also measured by the same machine. The refractive power of the lens was calculated by using the SRK formula. The patients were divided into 3 groups, myopia (SE<0), hyperopia (SE>+0. 50D) and emmetropia ( 0 to + 0. 50D ). Linear Correlation and Regression were used to evaluate the correlation among the optical parameters.
RESULTS:Totally 44 subjects, 88 eyes, average 9. 04±2.39 years, spherical equivalent (SE) -3. 50D to +8. 75D. Hyperopic AL was shorter than the other two groups ( P<0.05), same trend in lens power. No significant differences among the 3 groups in corneal K and ACD. There was a negative correlation between age and SE, SE and AL, SE and lens refractive power, and there was a positive correlation between age and AL, age and lens power.
CONCLUSION:As the children's growing up, SE trends to myopia, and AL becomes longer, and lens power is stronger.

Objective To investigate the effective predictors of response in HBeAg-positive patients treated with adefovir dipivoxil(ADV)and to provide evidence for individualized treatment.Methods Patients administered with ADV for 48 weeks in a randomized,placebo-controlled,multicenter trial were studied.Statistical analyses,such as Backward stepwise logistic regression and 2?2 method were used for predictors analysis at week 48.Results The baseline serum ALT levels,HBV DNA levels,and undetectable serum HBV DNA by PCR at week 24 were predictors for HBV DNA negativity at week 48.The median of serum ALT levels and HBV DNA levels prior to treatment were 134.5 U/L and 6.57 lg copies/mL,respectively.Patients with baseline ALT levels higher than the median,HBV DNA levels lower than the median,and serum HBV DNA undectectable by PCR at week 24 had greater rate of HBV DNA negativity(93.3%),HBeAg loss(60%)and HBeAg seroconversion(40%)at week 48 than the others.47.8% of patients whose HBV DNA levels were positive at week 24 also achieved HBV DNA negativity at week 48,and 8.6% achieved HBeAg seroconversion.Conclusion Better response at week 48 has significantly higher serum ALT levels and lower HBV DNA levels prior to treatment and HBV DNA negativity at week 24 compared with non-response.Patients whose HBV DNA levels ware still positive at week 24 should continue therapy.