1.Comparison of students' learning curves between Macintosh laryngoscope and Airtraq laryngoscope in endotracheal intubation
Hong ZHAO ; Yi FENG ; Yanyan ZHOU
Chinese Journal of Medical Education Research 2012;11(10):1020-1023
Objective To compare medical students' learning curve between Macintosh laryngoscope and optical laryngoscope in endotracheal intubation and to decide which one is more suitable for novice personnel.Methods Totally 26 interns after being trained by experienced anesthesiologists were enrolled in this study.They performed intubation on 6 patients by using both Macintosh laryngoscope and optical laryngoscope ( each laryngoscope for 3 patients) under the supervision of experienced anesthesiologists.The sequence of laryngoscope was determined by computer-generated random number list.Results Totally 149 patients who were ready to receive surgery under general anesthesia were enrolled in this randomized crossover controlled study.Duration of intubation was significantly shorter in Airtraq group (78 -± 33 ) s than in Macintosh group (114 ± 32) s,P < 0.001.Intubation success rate was significantly higher in Airtraq group than in Macintosh group ( 87.8% vs.66.7%,P < 0.05 ).Conclusions With the advantages of rapid learning curve,higher intubation success rate and shorter intubation duration,Airtraq laryngoscope is easier to master for novice personnel.
2.Analysis of dietary intake and nutrition in 400 pregnant women
Xuemei CHEN ; Shuguang ZHOU ; Hong FENG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(7):1194-1195
Objective To understand the dietary intake of pregnant women, and try to give a reasonable sug-gestion to promote fetal development. Methods 400 pregnant women in Fushan city were enrolled in this study and their dietary intake were investigated, then the software of Analysis of pregnancy nutrition guidance system was used to make nutrition analysis. Results The ratio of the energy in each pregnancy provided by dietary protein, carbohy-drate and fat were relatively appropriate. But the intake of dietary calcium, ferrum, zinc, vitamin B1 and vitamin B2 in early pregnancy were very low, the intake were respectively 764.51 mg, 26.94 mg, 15.71 mg, 1.12 g, 1.13 g. Each pregnancy the ratio of high-quallty protein in total protein intake were more than 50%, an average protein RNI% was 48.50%. Conclusion The dietary style of pregnant women is relatively reasonable. But they should strengthened nutritional guide to intake more calciuro,ferrum, zinc,vitamin B1 and vitamin B2.
3. The relationship between the serum levels of vascular endothelial growth factor (VEGF) basic fibroblast growth factor (bFGF) as well as the biological behaviors of gastric cancer
Tumor 2007;27(9):733-736
Objective: To discuss the relationship between vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and the biological behaviors of gastric cancer and, the relationship between the serum levels of VEGF, bFGF and the chemotherapeutic efficacy in patients with recurrent and metastatic gastric cancer. Methods: The serum levels of VEGF and bFGF were detected by ABC-ELISA method. Results: (1) The serum levels of VEGF and bFGF were significantly higher in preoperative stomach cancer patients than those in the healthy controls (P < 0.05) and postoperative stomach cancer patients (P < 0.05). (2) The serum levels of VEGF and bFGF significantly correlated with the depth of invasion, TNM staging, lymph node metastasis, and distant metastasis of primary cancer. (3) The serum level of VEGF had positive correlation with the serum level of bFGF in gastric cancer patients before radiochemotherapy (r =0.439, P <0.01). (4) The levels of VEGF and bFGF are significantly higher in preoperative patients with recurrent and metastatic gastric cancer than that in healthy controls and disease-free survival subjects (P < 0.05). After chemotherapy the serum levels of VEGF and bFGF in patients with no change (NC) or in progressive disease (PD) were a little higher than that before chemotherapy but the difference was not significant (P >0.05). (5) The serum levels of VEGF and bFGF were significantly lower in patients with complete response (CR) + partial response (PR) than that with NC + PD group after recurrent and metastatic patients received chemotherapy (P < 0.05). Conclusion: The serum levels of VEGF and bFGF were related with biological behaviors and chemotherapeutic efficacy of gastric cancer. The serum levels of VEGF and bFGF may provide new markers for preoperative diagnosis, postoperative follow-up, monitoring of the metastasis or recurrence of gastric cancer.
4.Effect of intrathecal injection of ?-conopeptide SO3 on inducible nitric oxide synthase expression in spinal cord and chronically constricted sciatic nerve in rat
Hong WANG ; Xiaowei ZHOU ; Zeguo FENG
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective To evaluate the effect of intrathecal administration of ?-conopeptide SO3 on inducible nitric oxide synthase(iNOS)expression of spinal cord and the ligated sciatic nerve in a rat model with chronic constriction injury(CCI).Methods 40 male SD rats were randomly divided into 4 groups of 10 animals each.Rats in the N group served as controls;in group C 4 loose ligatures were placed around the right sciatic nerve for 14 days;in group CN,normal saline 1?l/h was injected intrathecally slowly for 7 days seven days after the ligation;in group CS,?-conopeptide SO3 30ng/h was administered intrathecally slowly for 7 days seven days after the ligature.Local expression of iNOS was assayed in samples taken from injured nerves(between and distal to the CCI site)and the spinal cord using Western blotting analysis,with GAPDH as an internal reference.Results A 130 kDa band,corresponding to iNOS protein was detected in the middle and distal sections of the injured nerves and the spinal cord.The iNOS immunoreactivity was inhibited by continuous intrathecal injection of ?-conopeptide SO3.There was no difference in the expression of iNOS between group CN and group C.Conclusion The expression of iNOS in the spinal cord and injured nerves of CCI rats was enhanced.Intrathecal injection of ?-conopeptide SO3 can inhibit the expression of iNOS.The data suggested that N-type calcium channel blocker took part in the expression of iNOS.
7.Congenital analgesia: a case report and literature review.
Hong-Xia SHEN ; Jian-Feng ZHOU ; Jian-Nong CHAI
Chinese Journal of Contemporary Pediatrics 2009;11(3):197-198
Female
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Humans
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Infant
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Mutation
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Pain Insensitivity, Congenital
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complications
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genetics
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pathology
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Receptor, trkA
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genetics
8.Clinical observation and treatment of acute severe dimethyl sulfate poisoning.
Jin-zhou BI ; Hong-wei LIU ; Feng WANG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2007;25(2):120-120
Adolescent
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Adult
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Female
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Humans
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Male
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Occupational Exposure
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Poisoning
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diagnosis
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therapy
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Sulfuric Acid Esters
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poisoning
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Young Adult
9.Preparation of Ti-O Film Deposited on the Surface of a New Type of Artificial Mechanical Heart Valve.
Feng ZHOU ; Yuanyuan CUI ; Liangliang WU ; Hong SUN ; Nan HUANG
Journal of Biomedical Engineering 2015;32(2):430-433
The rutile structure titanium oxide (Ti-O) film was prepared on the pure titanium material TA2 (99.999%) surface by the magnetic filter high vacuum arc deposition sputtering source. The method can not only maintain the material mechanical properties, but also improve the surface properties for better biocompatibility to accommodate the physiological environment. The preparation process of the Ti-O film was as follows. Firstly, argon ions sputtered to the TA2 substrate surface to remove the excess impurities. Secondly, a metal ion source generated Ti ions and oxygen ions by the RF discharge. Meanwhile a certain negative bias was imposed on the sample. There a certain composition of Ti-O film was obtained under a certain pressure of oxygen in the vacuum chamber. Finally, X-ray diffraction was used to research the structure and composition of the film. The results showed that the Ti-O film of the rutile crystal structure was formed under the 0.18 Pa oxygen partial pressure. A Nano scratch experiment was used to test the coating adhesion property, which demonstrated that the film was stable and durable. The contact angle experiment and the platelet clotting experiment proved that the modified surface method had improved platelet adhesion performance, and, therefore, the material possessed better biocompatibility. On the whole, the evaluations proved the modified material had excellent performance.
Heart Valves
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Heart, Artificial
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Ions
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Materials Testing
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Oxygen
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Surface Properties
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Titanium
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X-Ray Diffraction
10.Outcome analysis of caspofungin in combination with voriconazole for treatment of 12 hematologic malignancies cases with invasive fungal infection.
Hong-Li SUN ; Xin ZHOU ; Yun-Feng SHEN
Chinese Journal of Hematology 2011;32(8):558-559
Adolescent
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Adult
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Aged
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Antifungal Agents
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therapeutic use
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Drug Therapy, Combination
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Echinocandins
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administration & dosage
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therapeutic use
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Female
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Hematologic Neoplasms
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drug therapy
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microbiology
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Humans
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Lipopeptides
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Male
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Middle Aged
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Mycoses
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drug therapy
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Pyrimidines
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administration & dosage
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therapeutic use
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Treatment Outcome
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Triazoles
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administration & dosage
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therapeutic use
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Voriconazole
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Young Adult