Objective To investigate the clinical efficacy of fire needle puncture combining with chinese herbal medicine for treating sciatica. Methods Sciatica outpatients were randomly allocated to a Fire needle puncture plus chinese herbal medicine of 37 cases( treatment group) and a western medication group of 32cases( comparison group). In the former, fire needle puncture and chinese herbal medicine was performed for two or three treatment courses; in the latter, only western medication was given during the same period. Results A comparison of the curative effects at one day after the treatment showed that the marked efficacy rate and effective rate in the treatment group were 78.4% and 97.20% respectively, and in the comparison group was 43.8% and 84.4%. The comparison of the curative effects between the two groups showed that all these patients got better in the treatment group than in the comparison groups and there was very significant difference ( P

ve To investigate the effects of different doses of diltiazem alone or combination with isoflurane on stunned isolated rat heart. Methods Adult male Wistar rats weighing 325-350g were anesthetized with intraabdominal pentobarbital sodium 60mg?kg-1. Heparin 200IU was injected into femoral vein. Chest was then opened and heart was removed and connected to Langendorff preparation. The isolated rat heart was perfused at 100cm H2O with Krebs-Hensleit buffer(KHB) balanced with 95%O2 and 5%CO2 at 37℃ and electrically paced at 300 bpm. Global myocardial ischemia was produced by suspension of perfusion. The isolated rat heart underwent 20 min ischemia followed by 30min reperfusion. 40 rat hearts were randomly allocated to one of 5 groups of eight each, group Ⅰ received no treatment and served as control; group Ⅱ: the isolated heart was perfused with 0.1/?mol?L-1 diltiazem for 10 min before the onset of ischemia; group Ⅲ: with 0.5?mol?L-1 diltiazem; group Ⅳ: with 0. 1?mol?L-1 diltiazem + 1.5MAC isoflurane; group Ⅴ: with 0.5?mol?L-1 diltiazem + 1.5MAC isoflurane. Left ventricle developed pressure(DP) was measured from a fluid-filled Latex balloon placed in left ventricle. The volume of the fluid in the balloon was regulated to maintain the left ventricle end-diastolic pressure at 5-8 mm Hg. Peak systolic pressure(PSP), end-diastolic pressure(EDP) and developed pressure(DP) were measured after the isolated heart was stabilized for 10min (baseline value) and 5, 10, 15, 20, 25, 30min after reperfusion. Maximum intraventricular pressure was measured during ischemia when the isolated heart was not paced and at a stand still. Results There was no significant difference in DP, EDP, + dp/dtmax and - dp/dtmin after the isolated hearts were stabilized for 10min, before ischemia among the five groups. Perfusion with 0.1?mol?L-1 diltiazem did not affect DP significantly but 0.5?mol?L-1 diltiazem significantly decreased DP (P

OBJECTIVE To explore optimal change dressing of the incision of trachea.METHODS Seventy-eight patients were randomly and equally divided into the traditional group and test group.In traditional group,after dressings change with conventional disinfection,the sterile gauze was cut into "E" shape and overlapping covered on the incision of trachea around the trachea cannula from top to bottom and fixed with adhensive plaster.In test group,after dressings change with conventional disinfection,the special sterile drainage was fixed and smoothed around the trachea cannula from left to right(or from right to left).RESULTS In test group,skin incision colonies of patients were significantly lower than that in traditional group(P

OBJECTIVE:To investigate the effects of clopidogrel plus atorvastatin on ischemic cardiovascular diseases and to explore the clinical significance of drug interactions.METHODS:Literatures were retreived from EMBase,PubMed,Cochrane Library and CNKI with clopidogrel,atorvastatin,clinical trial as

0.05).Conclusion The therapeutic mechanism of AEP of Chinese herbal medicine for asthma may be related with the inhibition of EOS infiltration,the decrease of peripheral IL-4 content and the increase of IFN-?.

Child ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Medicine, Chinese Traditional ; Phytotherapy ; Pneumonia, Mycoplasma ; diagnosis ; drug therapy

Objective To optimize the extraction conditions of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule.Methods Hyperin extraction rate was set as index, and HPLC was used for determination. The extraction conditions of ethanol concentration, ethanol quantity, extraction time and other factors were studied with orthogonal test and comparative test.Results Ethanol concentration and extracting times were remarkable factors in the test. The optimum extraction technology forJinzao Yuanzhi Capsule was to reflux and extract the materials with 8 times of 70% ethanol for 2 times, reflux extraction for 1.5 hours, filtration. Then 6 times of 70% ethanol was added for 1.5 hours’ reflux, filtering, and merging extracted liquid.Conclusion The optimum extraction technology is reasonable and feasible.

BACKGROUND:Alpha-calcium sulfate hemiydrate/biphasic bioceramics (α-CSH/BCP) as a bone repair material has been widely used in the clinic, but there are stil some deficiencies. OBJECTIVE:To observe the effect of α-CSH/BCP on the repair of bone defects of the radius in rabbits. METHODS:The unilateral radius of 18 adult New Zealand white rabbits was selected to establish bone defect models, and then these rabbit models were randomized into three groups that were treated with α-CSH,α-CSH/BCP, BCP materials, respectively. At 4, 8, 12 weeks after implantation, bone samples were taken for gross and X-ray observations. RESULTS AND CONCLUSION: (1) Gross observation: At 12 weeks of implantation, the bone defect was completely repaired in the α-CSH/BCP group, and the defected radius recovered basicaly; in the α-CSH group, bone defects were visible; and in the BCP group, there was stil some material for filing and coverage. (2) X-ray observation: In the α-CSH group, the degradation of implanted materials was faster than new bone formation, and bone defects were visible; in the α-CSH/BCP group, bone defects were healed, cortical bone remodeling was good, and the bone marrow cavity was re-canalized; in the BCP group, the implanted materials were stil visible, and bone defects were not repaired. These findings indicate that the α-CSH/BCP bone repair material can significantly promote the repair of bone defects of rabbit radius, with a better repair effect than α-CSH or BCP alone.

The system construction and work flow of automatic oral drug dispensing system(AODDS) in our hospital are introduced,its' advantages and disadvantages of the application are analyzed.After applying AODDS,drug dispensing speed and accuracy are significantly increased.AODDS is conducive to promote hospital pharmaceutical care and pharmacy quality administration.The application of AODDS in our hospital may be referred for other hospitals to select AODDS.