1.Regulation of Proenkephalin Gene Expression in Glial Cells.
Journal of Korean Society of Endocrinology 2000;15(6):750-759
No Abstract Available.
Gene Expression*
;
Neuroglia*
2.11 Cases of Aspergillosis.
Ho Won HWANG ; Jang Shin SOHN ; Chae Hong SUH
Korean Journal of Pathology 1985;19(3):325-331
Genus of aspergilli are ubiquitous saprophytic molds in nature, which are recognized about 700 species, at least eight are pathologic for human. Pulmonary aspergillosis is rare disease, most frequent presenting as secondary invasion, and aspergillosis of the nasal cavity is the most common sites of the extrapulmonary aspergillosis. Predisposing factors for pulmonary aspergillosis are chronic lung disease, tuberculosis, antibiotics, cytotoxins and neoplasia, hematologic disorders, and histoplasmosis etc. Authors have experienced 10 cases of pulmonary aspergillosis and a case of aspergillosis of nasal cavity in Dept. of Pathol. Chosun univ. hospital and christian hospital from Feb. 1981 to July 1984. Patient of pulmonary aspergillosis are received surgical resection and survived well without complications.
Humans
;
Cytotoxins
3.A Study of Vascular Changes in the Lymph Nodes.
Hye Suk SONG ; Ho Won HWANG ; Chae Hong SUH
Korean Journal of Pathology 1985;19(2):179-186
A retrospective morphological study was conducted on 1677 lymph nodes which were removed surgically under the diagnosis of gastric carcinoma, breast carcinoma, colonic carcinoma, chronic gastric ulcer, and superficial lymph nodes nuder the diagnosis of reactive follicular hyperplasia at Chosun University Hospital during a period of 5 years from 1980 to 1984. The hematoxylin and eosin stained sections were examined to evaluate for any vascular changes. In selected cases further levels were prepared from the paraffin blocks for Gomori's reticulin stain. The vascular abnormalities were divided into 3 groups, such as hemangiomatoid, pan-nodal vasodilatation and miscellaneous types. The miscellaneous type included the proliferation of smooth muscle which encircled numerous small hilar arteries and veins. The results obtained were as follows: 1) The hemangiomatoid lesions were localized lesions which appeared to be associated with local malignancy, but infrequent in incidence. 2) A more frequent vascular abnormality was pan-nodal vasodilatation, which tend to affect many nodes in a single group and is relatively associated with chronic gastric ulcer. 3) Miscellaneous lesion was nonspecific and appeared both local malignancy and chronic inflammation. 4) All three vascular reactions were somewhat more frequent in female than male.
Female
;
Humans
;
Incidence
4.An Immunohistochemical Study of Alpha-1-antichymotrypsin and Lysozyme in the Hofbauer Cells of Human Placentas.
Ho Won HWANG ; Ho Jong CHUN ; Chae Hong SUH
Korean Journal of Pathology 1988;22(1):63-69
The present study has shown that immunohistochemical staining of the human placentas (5 first trimester and 20 full term placentas) for confirmation of the monocytic linease of its macrophage function. We used two macrophage associated glycoprotein; alpha-1-antichymotrypsin (A1Ac) and lysozyme (LSZ). The results from presence or absence of A1Ac & LSZ by immunohistochemical methods can be helpful to deceide the degree of differentiation of macrophage. In al the placentas examined a strong cytoplasmic reaction for A1Ac was seen in the Hofbauer cells, and the same cells of serial sections didn't stain for LSZ. The strong cytoplasmic reaction for A1Ac supports that Hofbauer cells are macrophage, but they didn't stain for LSZ, a bactericidal enzyme, we propose that these cells are not fully differentiated macrophage. The lack of LSZ may have some relevance to the pathogenesis of certain placental infections.
Humans
5.An Experimental Study on Mixing of Chemoembolic Material for Hepatocellular Carcinoma.
Jong Hoon KIM ; Won Hyuck SUH ; Soon Joo CHA ; Jung Uk SUH ; Woo Ho CHO ; Won Hong KIM ; Gham HUR
Journal of the Korean Radiological Society 1994;30(6):1097-1103
PURPOSE: The chemoembolization with Lipiodol and doxorubicin hydrochloride is used in patients with hepatocellular carcinoma. What condition is the ideal emulsion of Lipiodol and doxorubicin for excellent anticancer effect? METHOD AND MATERIALS: Microscopic evaluation was performed on the emulsions, which were varied with different specific gravities of doxorubicin solutions, degrees in mixing of the emulsion, and amount of Lipiodol. RESULT: 1. Maximal amount of doxorubicin solution was contained in Lipiodol droplets and the release of doxorubicin from the droplets were delayed, when specific gravity of doxorubicin was equal to that of Lipiodol (SG, 1.28). 2. The optimal therapertic ratio of Lipiodol and doxorubicin was 3:2 at least, as in the emulsion less than 3:2, unmixed free forms of doxorubicin solution were increased. 3. The emulsion mixed by pumping 50--100 times had smaller Lipiodol droplets and contained larger amount of doxorubicin solution in the droplets than by pumping 20 times. CONCLUSION: We recommend the emulsion with specific gravity of doxorubicin equal to Lipiodol (SG. 1.28), the ratio of Lipiodol and doxorubicin closo to 3:2, and the mixture prepased with puming 50--100 times.
Carcinoma, Hepatocellular*
;
Doxorubicin
;
Emulsions
;
Ethiodized Oil
;
Humans
;
Specific Gravity
6.Artifacts by dental materials on magnetic resonance imaging.
Hyun Sook HONG ; Deuk Lin CHOI ; Ki Jung KIM ; Won Hyuck SUH
Journal of the Korean Radiological Society 1992;28(3):463-469
Magnetic resonance imaging(MRI)has proved to be a valuable method for evaluation of the head and neck. Unfortunately, metallic devices associated with certain dental fillings and applicances often cause variable artifacts that can obscure normal or pathologic conditions on MR and computed tomography. In this work, we assessed the MR appearance of dental prosthetic materials in vitro and in vivo including precious alloys. Nonprecions alloys, resin, amalgam and titanium alloy, For in vivo studies, these materials were placed in healthy volunteer's mouths and then images were assesed. Analyis of the appearance of shape and extent of artifact,and observed influence of these artifacts on the image interpretation at 0.2 Tesla permanent type MR scanner were valuated. Material used as temporary or permanent filling of crowns such as amalgam. precious alloy and, microfilled resin did not cause artifact on the image. The size of the artifact produced by the nonprecious alloys was influenced by the ferromagnetism of the object and the volume prosthesis, and was related to the scanning sequence. Nonprecious alloys produced minimal local signal distortions, where precious alloys, and dental resin had no effect on the MR image in vivo. These results were mainly from a low field strength MR scanner used in this study.
Alloys
;
Artifacts*
;
Crowns
;
Dental Materials*
;
Equidae
;
Head
;
In Vitro Techniques
;
Magnetic Resonance Imaging*
;
Magnets
;
Methods
;
Mouth
;
Neck
;
Prostheses and Implants
;
Resins, Synthetic
;
Silicone Elastomers
;
Titanium
7.A Case of Neuroblastoma Originated from Mediastinum.
Suh Hong HA ; Won Kyung KIM ; Kyung Tae KIM ; Jung Hee LEE
Journal of the Korean Pediatric Society 1985;28(7):714-719
No abstract available.
Mediastinum*
;
Neuroblastoma*
8.The comparative study of bone substitute materials in bone regeneration.
Jung soo HONG ; Jeong Cheol KIM ; Dong Bo SUH ; Jung Hyun SEUL ; Won Hee CHOI
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(4):549-559
No abstract available.
Bone Regeneration*
;
Bone Substitutes*
9.Surgical analysis of mediastinal tumors.
Seog Jae LEE ; Sook Whan SUNG ; Jong Myun HONG ; Pil Won SUH ; Joo Hyun KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(5):395-402
No abstract available.
10.Cellulitis in Young Adults.
Sung Ho HAHN ; Bo Kyu YANG ; Chi Hong KIM ; Tae Won AHN ; Sung Kyo SUH
The Journal of the Korean Orthopaedic Association 1998;33(3):614-619
While the microbiology of cellulitis in the pediatric population and systemic diseases(DM, Cirrhosis, etc) is well known,the causative bacteria and clinical aspect of cellulitis in young adults are less descrihed. this study was undertaken to identify the causative organisms and clinical aspect of adult cellulits. We analysed 121 medical records of 115 young adult patients with cellulitis who had been admitted at the department of orthopaedic surgery, National Police hospital from Jan. 1994. to Dec. 1996. The results were as follows. 1. The age of patient was between 21 yrs and 25 yrs, and the sex of all patients was male. 2. The lower leg and foot were the most frequently involved site of cellulitis as 92 cases(74.2%). 3. The potals were suspected in 65 cases(56.5%),of them, traumas were detected in 43 cases(66.1%), non-traumatic skin lesions in 23 cases(33.9%). 4. In most cases, initial systemic symptoms (fever, chill, headache, etc.) and local symptoms (local heating, tenderness, etc.) were found. 5. The laboratory findings revealed leukocytosis in 19%, elevated ESR in 94%, positive CRP in 80%. 6. Microorganism were detected in 16 of 38 pus cultures. Gram positive microorganisms were detected in 15 of 16 cases culture positive. 7. 6.7% of patients with cellulitis experienced recurrence in same lesions. In conclusion, the retrospective analysis of 115 young adult patients with cellulitis showed that primary cause of young adult cellulit was circulatory disturbance and lymphatic obstruction of the lower extremities most often involved by trauma. therefore, supportive treatments such as rest,elevation,ice packs are considered prior to antibiotic treatment.antibiotic treatment aimed at gram-positive cocci appears to be sufficient.
Adult
;
Bacteria
;
Cellulitis*
;
Fibrosis
;
Foot
;
Gram-Positive Cocci
;
Headache
;
Heating
;
Hot Temperature
;
Humans
;
Leg
;
Leukocytosis
;
Lower Extremity
;
Male
;
Medical Records
;
Police
;
Recurrence
;
Retrospective Studies
;
Skin
;
Suppuration
;
Young Adult*