1.Experimental study on rat corneal endothelial damage and repair after acid burn
Journal of Third Military Medical University 2003;0(11):-
Objective To study the effect of acid burn on rat corneal endothelial damage and its repair.Methods The model of mild,moderate and severe acid burn in cornea was established in 90 Long-Evans rats(n=30 for each degree of acid burn) with 4 rats served as normal controls.Corneal edema,opacity and the healing of epithelium were observed with a slit lamp microscope.The corneal endothelium from half rats of each degree acid burn was stained with trypan blue and alizarin red,and that from the other half with hematoxylin and eosin(HE) immediately,30 min,1,3,7,14,21,28 d after cautery.The endothelial damage and its repair were observed and the number of the leucocytes in cornea was calculated under light microscope.Results No damage was seen in the corneal endothelial cells of mild,moderate acid burn,only a few leucocytes could be seen in the cornea,and the healing of epithelium,the regression of edema were within 7 d.The endothelial cells necrosed and shedded in the wound area by severe acid burn.The endothelial cells in the margin were deformed,elongated and slided to the damaged area during repair,and a great number of leucocytes infiltrated,the healing of corneal epithelium was delayed,the regression of edema was up to 28 d.Conclusion The corneal endothelial cells were damaged in severe acid burn.The secondary inflammatory reaction took part in the damage of corneal endothelial cells after severe acid burn.The damage of endothelial cells delayed the healing of corneal ulcer and edema.
2.Study with a method of excluding AC disturbances in MRI
Chinese Journal of Radiology 2000;0(11):-
Objective To exclude AC disturbances resulted from ambient condition in the process of magnetic resonance imaging. Methods study ten low field MRI systems and analysis the images with AC disturbance, then compare measured data of ambience, one of which is disturbed seriously, the other is no disturbance. By removing the power lines and adding isolating transformers and eliminating metal pipes and so on, the useful method is summarized. Results Magnetic field strength giving rise to AC disturbances ranges from 2 mGs to 4 mGs (the standard is less 1 mGs). It will produce circle artifacts. The artifacts pass away when magnetic field strength was decreased to 1 mGs. Conclusion installing MRI sets, disturbing resources must be 10 m far away from them.
3.Expressions and significances of sICAM-1 and sCD44v6 in peritoneal lavage fluid after laparoscopically assisted radical gastrectomy
Journal of International Oncology 2014;41(11):872-874
Objective To explore the expressions and significances of sICAM-1 and sCD44v6 in peritoneal lavage fluid after laparoscopically assisted radical gastrectomy,in order to evaluate the risk of laparoscopically assisted radical gastrectomy for the peritoneal plant transfer.Methods Ninety-two patients with gastric cancer were randomly divided into the control group and the experimental group.The control group was treated with open laparotomy and the experimental group was treated with laparoscopic surgery.The concentrations of both sICAM-1 and sCD44v6 were detected by enzyme linked immunosorbent assay.The positive rates of tumor cells in the two groups were compared.Results The expressions of sICAM-1,sCD44v6 in the two groups before operation had no significant difference (t =0.198,P =0.543 ; t =0.897,P =0.429).After operation,sICAM-1 and sCD44v6 levels increased significantly,but there was no significant difference between the two groups (t =0.766,P =0.312 ; t =1.092,P =0.129).The positive rates of tumor cells in the two groups before and after operation have no significant differences (x2 =0.789,P =0.287 ; x2 =0.912,P =0.198).Conclusion Laparoscopically assisted radical gastrectomy does not increase the expression of sICAM-1 and sCD44v6 in peritoneal lavage fluid and the risk of peritoneal metastasis.It is worthy of clinical poptdarization and application.
4.Combined implantation of auto-limbal epithelium and amniotic membrance for treatment of symblepharon
Chinese Journal of Primary Medicine and Pharmacy 2008;15(9):1478-1479
Objective To observe the auto-limbal epithelium and amniotic membrance transplantation in treatment of Symblepharon.Methods Transplant with auto-limbal epithelium and aminiotie membrance including 23 patients (31eyes) some of them are recurrentcd pterygium,most of them are symblepharons.[ Result ] In the followup period for 3~12 months,Ocular surface reconstruction was successful in 26 of 31 eyes with symb|epharon,but five of them recurrented three months later with lees than pre-transplantation in degree.Conclusion The transplantation with auto-limbal epithelium and membrance transplantation is an effective method for the symblepharon.
5.Development of transcranial magnetic stimulator and measurement of the magnetic field distribution
Chinese Medical Equipment Journal 2004;0(08):-
This paper introduces general guidelines for designing and constructing a magnetic stimulator (MS). These guidelines cover the theoretical concepts, hardware aspects and necessary components. RLC model producing the impulses in MS is focused on and the way to calculate the parameters of the model is presented. Some factors that influence induced magnetic field are discussed. Experiments are carried through with self-developed round coil and 8-shaped, and Tesla meter is used to detect the magnetic fields. The experiments data show that the distribution of the induced magnetic fields by the two coils are tailored to those of theoretical calculation adopted now. A simulation experiment to measure magnetic field in brain has been completed.
6.Law Risk and Precaution of Pharmacist
China Pharmacy 2005;0(22):-
OBJECTIVE:To enhancement lawconsciousness and ability of self-protect of pharmacist.METHODS:Analysed the problem which occured in their work from the point of view of law and bring forward some advice.RESULTS &CONCLUSION:Pharmacist should do their work strictly according to the code for avoidance law risk.
7.Practice and Exploration of the Guidance of Undergraduate Thesis in Preventive Medicine
Chinese Journal of Medical Education Research 2002;0(01):-
This paper briefly analyzes the main factors influencing the quality of the undergraduate thesis and points out that the guarantee of improving the quality is to strengthen the management of undergraduate thesis,improve overall capacity of teachers and train general capability and good attitude of students,etc.
8.Clinical efficacy of Longxuejie joint cobamamide in the treatment of elderly patients with herpes zoster
Chinese Journal of Primary Medicine and Pharmacy 2014;(19):2963-2964
Objective To investigate the clinical efficacy of cobamamide combined with Longxuejie in the treatment of herpes zoster in the elderly .Methods 104 elderly patients with herpes zoster were randomly divided into the treatment group and the control group .Both the two groups were given orally famciclovir 250mg,3 times a day for 14 days,intramuscularly injected gland glycosides cobalamin 500mg,1 day,14 days a course of treatment ,the treat-ment group was given Longxuejie enteric-coated tablets 4,3 times a day orally for 14 days.The blisters disappeared , pain relief,and recovery time of completely crusted ,treatment efficacy and neuralgia were compared between the two groups.Results In the treatment group,34 cases were cured,effective in 13 cases,total effective rate was 90.4%, which was significantly higher than 73.1% in the control group,the difference was statistically significant (χ2 =5.216,P<0.05).The blisters disappeared,pain relief,and recovery time of completely crusted in the treatment group were significantly shorter than those in the control group (t =3.216,5.432,4.643,3.654,all P <0.05).No postherpetic neuralgia was observed in the treatment group ,the incidence rate of postherpetic neuralgia of the control group was 13.5%,the difference was statistically significant (χ2 =4.875,P<0.05).Conclusion The Longxuejie combined with cobamamide in the treatment of herpes zoster in elderly patients has reliable effect ,fast improvement of clinical symptoms,a low incidence of postherpetic neuralgia ,it is worthy of clinical application .
9.Perspectives on Legal Guarantee of Licensed Pharmacists in Medical Service
China Pharmacy 2005;0(16):-
OBJECTIVE: To enhance the quality of pharmaceutical care of licensed pharmacists in medical services, and to ensure safe, effective, economical, and rational use of drugs. METHODS: The status quo and the problems existing in the legal guarantee of licensed pharmacists in medical service were analyzed, and the necessity of reinforcing legal guarantee for licensed pharmacists in medical service and the feasible measures were discussed. RESULTS & CONCLUSIONS: It is urgent to set and enforce "Licensed Pharmacist Law" to safeguard the legal rights of licensed pharmacists in medical service in the mo-de of law, facilitate the implementation of licensed pharmacist system in medical service, consummate management on licensed pharmacists, reinforce licensed pharmacists' consciousness of legal guarantee, and enhance the quality of pharmaceutical care.
10.A comparative study of quality of life between students of three-gorges reservoir and non-three-gorges reservoir in chongqing
Journal of Chongqing Medical University 2007;0(09):-
Objective:To study the status quo of quality of life and its influencing factors among Junior High School Students of Three-Gorges Reservoir and Non-Three-Gorges Reservoir in Chongqing,and to provide basis for students' QOL improvement.Methods:672 Three-Gorges Reservoir students and 630 Non-Three-Gorges Reservoir students were tested by using the Quality of Life Scale for Junior High School Students(JHSS-QOLS).Multiple stepwise regression analysis was utilized to study the major factors affecting QOL of students in Chongqing.Results:The quality of life of junior high school students in Three-Gorges Reservoir was higher than that of students in Non-Three-Gorges Reservoir.Physical exercises,sleep,chronic disease,parental rearing style were important influencing factors in quality of life of students.Conclusions:The key steps of improving the quality of life of Junior High School Students should include reducing the learning load of students,the prevention and control of chronic disease and the improvement of parental educational level.