1.Progress of Experimental Trichophyton Verrucosum Infection in Guinea Pig.
Hyun Sug KIM ; Jong Su CHOI ; Ki Hong KIM
Yeungnam University Journal of Medicine 1989;6(1):47-57
T. verrucosum Infection has been reported for the first time in 1986 in Korea and has been increasing progressively. To evaluate the progress of clinical and histopathological change of dermatophytosis caused by T. verrucosum, inoculation study, using T. verrucosum isolated from infected human (human strain) and from infected cattle (cattle strain), was done in 24 male albino Hartley guinea pig. Their clinical and histopathological changes were evaluated. In addition, comparison for the growth rate between human strain and cattle strain on Sabouraud's glucose agar was made. The results were as follows: 1. Growth rate on Sabouraud's glucose agar: Cattle strain showed significantly more rapid growth rate than human strain on Sabouraud's glucose rate at 25℃ and 37℃. And cattle strain showed more rapid growth rate at 37℃ than 25℃. But human strain showed no significant difference of growth rate at both temperature. 2. Clinical findings: Initial erythema, scale and crust were developed about 8th after inoculation. All three findings reached maximum severity about 12th to 16th day and disappeared about 30th to 34th day after inoculation. There was no significant difference in progress of erythema, scale and crust between cattle strain and human strain. 3. Histopathological findings: Although mild acanthosis was noticed on the 3rd day after inoculation, the other findings including parakeratosis, intraepidermal abscess, spongiosis and vascular change, cellular infiltration were found on 9th day after inoculation. They reached maximum severity on the 12th day and lasted to the 25th day after inoculation. After that, all three findings were decreased gradually between 29th day and 33th day. On the PAS staining, hyphae and spores were found on the 6th day and disappeared on the 21th day after inoculation. 4. In trichophyton skin test, all of the 24 guinea pigs became positive within average 9.83±1.17 days These findings suggested that dermatophytosis caused by T.verrucosum induced rapid cell mediated immunity and contributed to rapid resolution of the lesion.
Abscess
;
Agar
;
Animals
;
Cattle
;
Erythema
;
Glucose
;
Guinea Pigs*
;
Guinea*
;
Humans
;
Hyphae
;
Immunity, Cellular
;
Korea
;
Male
;
Parakeratosis
;
Skin Tests
;
Spores
;
Tinea
;
Trichophyton*
2.Changes of Cerebral Blood Flow Velocity before and after Closure of Ductus Arteriosus using Doppler Ultrasound in NormalFull-term Newborns.
Myung Su LEE ; Young Mi HONG ; Kyung Hee KIM
Journal of the Korean Pediatric Society 1995;38(12):1620-1628
No abstract available.
Blood Flow Velocity*
;
Ductus Arteriosus*
;
Humans
;
Infant, Newborn*
;
Ultrasonography*
3.Leriche syndrome: 1 case.
Young Sang GO ; Ja Hong KUH ; Kong Su KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(10):808-811
No abstract available.
Leriche Syndrome*
4.Primary Pyogenic Psoas Abscess in Child
Chin Hong KO ; Su Chan LEE ; Sang Gyu KIM
The Journal of the Korean Orthopaedic Association 1995;30(4):1092-1098
Primary pyogenic psoas abscess is rare lesion, and often is not suspected. Reasons for delayed diagnosis are unfamility with the lesion and the fact that symptoms often resemble those of primary disease of the hip. We present a case of primary pyogenic psoas abscess in child, which was diagnosed by MRI, and completely recovered after surgical treatment.
Child
;
Delayed Diagnosis
;
Hip
;
Humans
;
Magnetic Resonance Imaging
;
Psoas Abscess
5.Partial Monosomy 21 Associated with Unbalanced t(10p; 21q).
Bon Su KOO ; Sang Uk PARK ; Jae Hong PARK ; Su Yung KIM
Journal of the Korean Pediatric Society 1995;38(8):1146-1150
No abstract available.
Chromosome Deletion*
7.A Clinical Study on Childhood Systemic Lupus Erythematosus.
Young Jun KIM ; Young Don KIM ; Jae Hong PARK ; Su Young KIM ; Hee Ju PARK
Journal of the Korean Pediatric Society 1994;37(9):1235-1244
To Evaluate the clinical characteristics of childhood-onset systemic lupus erythemoatosus (SLE) and analyse the factors related to outcome of renal function in lupus nephritis, we reviewed medical records of 18 cases of SLF diagnosed at the Department of Pediatrics. Pusan National University Hospital from January 1981 to December 1990. The results were as follow: 1)Male to female ratio was 1:2.6. 2) Nephropathy was the most common initial impression, and 8 cases were diagnosed as SLE at first. 3) The clinical menifestation. was ANA (+), malar rash, renal disorder, hematologic disorder in frequency. 4) Diffuse proliferative lupus nephritis was the most common in renal histopathologic studies. 5) Among the follow-up cases, active lupus was 39%, remission was 28%. 6) As factors related to outcome of lupus nephrits were, hypertension and proteinuria were siginificant statistically.
Busan
;
Exanthema
;
Female
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Lupus Erythematosus, Systemic*
;
Lupus Nephritis
;
Medical Records
;
Pediatrics
;
Proteinuria
10.A Clinical Study of Recurrent Headaches in Children and An Application of International Headache Society Classification to Children.
Sang Su PARK ; Kwang Yeul BAE ; Tae Hong KIM ; Eun Jung KIM ; Kyu Geun HWANG
Journal of the Korean Child Neurology Society 1997;5(1):95-105
PURPOSE: Headache is a frequent symptom in pediatric practice, but the prevalence of chronic recurrent headache was estimated in several studies with wide variations, because of inadequate expression and differences in case definition in children. Headache classification of International Headache Society is usually used in adults, but the application of it to children is uncommon, so we tried to diagnosis children with headache by using International Headache Society Classification. METHODS: We analyzed the clinical pictures, physical examinations including neurologic examination, PNS series, EEG and CT or MRI in 53 children with nonprogressing recurrent headache over than one month, who visited to pediatric department of Dong-A University hospital from January, 1995 to Feburary, 1996 and diagnosed them by using International Headache Society Classification. RESULTS: 1) The sex ratio between male and female was 1:1.2. 2) Diagnosed groups consisted of children with migraines in 22 cases(41.5%), tension-type headache in 19 cases(35.9%), coexisting migraine and tension-type headaches in 5 cases(9.4%), miscellaneous headaches not associated with structual lesion in 1 case(1.9%), headache associated with vascular disorders in 2 cases(3.8%), headache associated with nonvascular intracranial disorder in 1 case(1.9%), headache due to facial pain in 3 cases(5.6%). 3) Of 22 migraine cases, 13 cases(59.1%) had migraine with aura, 8 cases(40.9%) have migraine without aura and of 19 tension-type headache cases, 8 cases(42.1%) have episodic type, 11(57.9%) cases have chronic type. 4) Of 53 cases with recurrent headache, 3 cases(6%) had abnormal findings in CT or MRI. 5) Of 53 cases with recurrent headache, 9 cases(17%) had abnormal findings in EEG. CONCLUSIONS: International Headache Society Classifications are useful, but the diagnostic criteria are too strict for children, especially in migraine and tension type headache.
Adult
;
Child*
;
Classification*
;
Diagnosis
;
Electroencephalography
;
Facial Pain
;
Female
;
Headache*
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Migraine Disorders
;
Migraine with Aura
;
Migraine without Aura
;
Neurologic Examination
;
Physical Examination
;
Prevalence
;
Sex Ratio
;
Tension-Type Headache