1.Study on antigenic analysis and serial antibody titration by using leptospira interrogans isolated at Chungchongbukdo.
Kyung Hee PARK ; Seok Cheol HONG ; Woo Hyun CHANG
Journal of the Korean Society for Microbiology 1991;26(4):317-327
No abstract available.
Chungcheongbuk-do*
;
Leptospira interrogans*
;
Leptospira*
2.Mycosis Fungoides Treated with PUVA.
Ee Seok LIM ; Yong Wook PARK ; Chang Kwun HONG ; Byung In RO ; Chin Yo CHANG
Korean Journal of Dermatology 1987;25(2):283-288
We report a case of mycosis fungoides in a 37 year-old male patient who had relatively well defined, irregular, erythematous plaques covered with acales on the buttock, lower extremities, anterior chest and back. Histopathological findings showed epidermotropism and Pautrier microabscesses in the epidermis and infiltration of atypical lymphocytes in the upper dermis. Electron microscopic findings showed mycosis cells with convoluted nuclei and prominent nucleolei He had been received PUVA therapy combined with topical and systemic corticosteroid for 4 months. Skin lesions were improved markedly after treatment with total 262 joules/crn2 and then maintained with 14 joules/cm2 in every week.
Adult
;
Buttocks
;
Dermis
;
Epidermis
;
Humans
;
Lower Extremity
;
Lymphocytes
;
Male
;
Mycosis Fungoides*
;
PUVA Therapy
;
Skin
;
Thorax
3.Combination chemotherapy with TAD(6-thioguanine, Ara-C and daunorubicin) in acute myelogenous leukemia.
Hong Seok AHN ; Yong Cheol LEE ; Chang Hun PARK ; Chang Yeol YIM
Korean Journal of Hematology 1991;26(1):73-80
No abstract available.
Cytarabine*
;
Drug Therapy, Combination*
;
Leukemia, Myeloid, Acute*
4.A case of pretibial myxedema.
Seok Hun HONG ; Joo Hyeup LEE ; Seong Jun SEO ; Chang Kwun HONG ; Byung In RO
Korean Journal of Dermatology 1992;30(2):239-243
Pretibial myxedema, which consists of localized cutaneous accumulations of acid mucopolysaccharides, oceurs in a few patients with hyperthyroidi';m after its correction by surgery or radioactive iodine therapy. We report a case of pretibial myxedema with exophthalmos in a 36 year old male. He has suffered from hyperthyroidism with bilateral pretibial myxedema for a period of 4 years. He was treated with a subtotal thyroidectomy and excision of both pletibia lesions 1 year ago. The lesions recurred on t,he left pretibial area, as a 11 X 16cm sized, non pitting, non tender, swollen, brownish plaque. The histopathologic findings showed epidermal hyperkeratosis and a considerable arnount of mucin in the mid-dermis. We treat.ed him with intralesional injection of triamcinolone acetonide with marked improvement.
Adult
;
Exophthalmos
;
Glycosaminoglycans
;
Humans
;
Hyperthyroidism
;
Injections, Intralesional
;
Iodine
;
Male
;
Mucins
;
Myxedema*
;
Thyroidectomy
;
Triamcinolone Acetonide
5.A Case of Cutaneous Horn of the Penis Associated with Squamous Cell Carcinoma.
Seok Hun HONG ; Seong Jun SEO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 1993;5(2):137-140
Cutaneous horns of the penis are rare. We report a case associated with squamous cell carcinoma in a 56-year-old male. A gradually enlarging nodule had been on the glans penis for four years. He had suffered from an erythematous crusted tumor mass and horny excrescence on the glans penis which recurred and was aggravated after excision of the nodule seven months ago. Histopathologic findings of the lesions showed characteristic findings of squamous cell carcinoma and cutaneous horn. In situ DNA hybridization for human papillomavirus types 6, 11, 16, 18, 32, and 33 were all negative. The tumor mass were surgically excised and we have not found any sign of recurrence since then.
Animals
;
Carcinoma, Squamous Cell*
;
DNA
;
Epithelial Cells*
;
Horns*
;
Humans
;
Male
;
Middle Aged
;
Penis*
;
Recurrence
6.A Clinical Study of Supracondylar Fracture of the Humerus in Children
Jay Suck CHANG ; Seok Hyun LEE ; Hong Chul LIM ; Seyng Soo HONG
The Journal of the Korean Orthopaedic Association 1989;24(1):139-147
Supracondylar fracture of humerus is the most common fracture about the elbow in children and much has been written about its treatment and the prevention of both Volkmann's ischemia with contracture and cubitus varus deformity. In a retrospective survey of 155 children with supracondylar frscture of the humerus, 63 cases were found to have sufficient clinical and retrospective data to classify the fracture. 1. The average age was 6.5 years ranged from 1 year 3 months to 14 years and sex ratio was 2.2: 1(M:F) 2. 62 cases(98.4%) were extension type and 1 case(1.6%) was flexion type. In extension type, displacement was posteromedial 30 cases(47.6%), posterolatera117 cases(26.9%), posterior 10 cases(15.9%) and undisplaced 5 cases(7.9%). 3. Fracture level was divided into 3 Groups. Trans-olecranon fractures were 47 cases(74.6%), proximal to olecranon fractures were 11 cases(17.5%) and distal to olecranon fractures were 5 cases(7.9%). According to age distribution lower age group involves the distal part and higher age group involves proximal part. 4. Transverse fractures were 39 cases(61.9%) and oblique fractures were 24 cases(38.1%). In oblique fracture, postero-anterial oblique fractures were 19 cases(30.2%), medio-lateral oblique fractures 3 cases(4.8%), and latero-medial 2 cases(3.2%). In oblique fractures redisplacements were more common in P-A oblique csse. 5. In the treatment of fracture, 31 cases(49.2%) were treated with closed reduction and percutaneous pinning, 26 cases(41.3%) were treated with closed reduction and splint immobilization, 3 cases(4.8%) were treated with open reduction and K-wire fixation, 3 cases(4.8%) were treated with skeletal traction. 6. Functional results according to degree of initial displacement was worse in some displaced(Grade II) cases, rather than total displaced (Grade IV) or displaced with rotation (Grade III) cases. 7. Complications in splint immobilzation method were cubitus varus deformity 2 cases, nerve injury 2 case, and in k-wire fixation method, nerve injury 5 cases and pin migration 1 case.
Age Distribution
;
Child
;
Clinical Study
;
Congenital Abnormalities
;
Contracture
;
Elbow
;
Humans
;
Humerus
;
Immobilization
;
Ischemia
;
Methods
;
Olecranon Process
;
Retrospective Studies
;
Sex Ratio
;
Splints
;
Traction
7.A clinical study of supracondylar closing wedge osteotomy for cubitus varus.
Seok Hyun LEE ; Jae Suk CHANG ; Hong Chul SIN ; Jun Suk HONG
The Journal of the Korean Orthopaedic Association 1993;28(1):240-246
No abstract available.
Osteotomy*
8.The Irritancy of Hand Dishwashing Liquids on the Skin.
Kang Seok LEE ; Seong Jun SEO ; Myeung Nam KIM ; Chang Kwun HONG ; Byung In RO
Annals of Dermatology 1999;11(1):13-18
BACKGROUND: The regular use of soaps and synthetic detergents has been associated with skin dryness and aggravation of dermatological conditions. OBJECTIVE: Our purpose was to investigate the irritancy of 10 hand dishwashing liquids on normal skin. METHODS: The skin changes, responding to repeat patch testing with 10 hand dishwashing liquids, were measured by visual scoring. RESULTS: The results are summarized as follows; 1. Of the 16 healthy volunteers 8 had reactions. 5 women and 3 men, but there was no significant difference in irritancy between men and women. 2. The mean irritancy scores of the 10 hand dishwashing liquids ranged from 0.06 to 0.88. 3. A prominent increase in the degree of erythema in the first 24 hour patch test did not persist beyond exposure day 5, but after day 5, augmented responses of the erythema and scales, even fissuring occurred. 4. The pH of the test solutions of the hand dishwashing liquids ranged from 5.0 to 6.0, but there appeared to be no correlation between pH and irritancy in the dishwashing liquids tested. CONCLUSION: Our data suggests that regular exposure to hand dishwashing liquids may cause disturbances of the skin in a substantial proportion of individuals, and workers should use hand dishwashing liquids in lower concentrations than recommended and only for short periods with protective measures.
Detergents
;
Erythema
;
Female
;
Hand*
;
Healthy Volunteers
;
Humans
;
Hydrogen-Ion Concentration
;
Male
;
Patch Tests
;
Skin*
;
Soaps
;
Weights and Measures
9.A Case of Maffucci's Syndrome Associated with Spindle-cell Hemangioendothelioma.
Kang Seok LEE ; Byung Hwan CHUN ; Seong Jun SEO ; Chang Kwun HONG ; Byung In RO
Annals of Dermatology 1998;10(3):203-207
A case of a 21-year old female with Maffucci's syndrome is presented where the patient developed multiple cutaneous spindle-cell hemangioendotheliomas. She had multiple pea to walnut sized, non-tender, normal skin colored or slight bluish nodules and bony mass-like lesions on the left upper extremity and hand. A histological examination of the lesions showed that they were composed of irregularly dilated, thin walled cavernous blood spaces containing phleboliths and collapsed vascular spaces separated by spindled fibroblastic cells. Radiologically, the bony lesions showed radiolucent densities with calcified spots within the second proximal phalanx and metacarpal bone of the left hand, which were consistent with enchondromas.
Chondroma
;
Female
;
Fibroblasts
;
Hand
;
Hemangioendothelioma*
;
Humans
;
Juglans
;
Peas
;
Skin Pigmentation
;
Upper Extremity
10.A Case of Infantile Digital Fibromatosis.
Kang Seok LEE ; Seong Jun SEO ; Chang Kwun HONG ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 1999;11(3):174-178
We report a case of infantile digital fibromatosis in a 34 month-old boy, who presented with a painless subcutaneous tumor on the medial aspect of the left third toe. A histological examination showed scattered small, round eosinophilic inclusion bodies in the cytoplasm of the tumor cells, which was consistent with infantile digital fibromatosis. A'immunohistochemical study revealed that desmin, a-smooth muscle actin, and vimentin were clearly positive in the cytoplasm of the tumor cells, but the inclusions themselves showed negative staining, thus indicating a hollow-like staining pattern. Electron microscopy showed either well-defined or ill-demarcated dense bodies in the cytoplasm of the tumor cells. In some areas, small vesicles and intracellular organells were observed' in the inclusions. In the course of conservative treatment, a new lesion developed on the lateral aspect of the left third toe, seven months after the appearance of the initial lesion.
Actins
;
Cytoplasm
;
Desmin
;
Eosinophils
;
Fibroma*
;
Humans
;
Inclusion Bodies
;
Male
;
Microscopy, Electron
;
Negative Staining
;
Toes
;
Vimentin