Anemia diagnosed early in pregnancy is associated with increased risks of low birth weight and preterm delivery. The purposes of this study were to assess the maternal iron status during pregnancy and to evaluate the relationships between the iron indices of maternal-umbilical cord serum iron and ferritin levels and pregnancy outcomes. Dietary intakes of the pregnant women were estimated by 24 hour-recall (3 times). Serum iron and ferritin levels in maternal blood and umbilical cord were measured at 1st-, 2nd-, 3rd- trimester and delivery, respectively. The mean of maternal serum iron levels of the trimester and delivery were 124.27microgram/dl, 97.03microgram/dl, 94.32microgram/dl, and 145.53microgram/dl. Those maternal levels were significantly lower than that of umbilical cord blood (222.59microgram/dl). Serum ferritin levels of maternal trimester and delivery were 22.68microgram/l, 11.09microgram/l, 14.18microgram/l and 24.54microgram/l, which were significantly lower than those of umbilical cord blood (184.35microgram/l)(p<0.0001). This prevalence of anemia of total subjects was 30.3% by WHO criteria (Hb<11.0 g/dl, Hct<33%). Iron levels of 2nd-trimester was significantly higher in the normal group than in the anemia group. And ferritin levels of 3rd-trimester and delivery was significantly higher in the normal group than in the anemia group. Therefore, we suggest for successful pregnancy outcome and delivery differential iron supplementation programs will be carried out with individual pregnant women on the basis of pre-pregnancy nutrition.
Anemia ; Female ; Ferritins ; Fetal Blood* ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Iron* ; Pregnancy Outcome ; Pregnancy* ; Pregnant Women ; Prevalence ; Umbilical Cord*

This study was performed to investigate nutritional intakes and preference food and blood composition of female college students of premenstrual syndrome. Based on physical measurement test results, both groups showed no noticeable difference and both groups were within the normal range according to body composition analysis. In terms of nutrients consumption, results showed nutritional intakes more than EAR (estimated average requirements) included phosphorus > vitamin B6>vitamin B1, while nutritional intakes less than EAR were vitamin A > vitamin B2> calcium > folic acid. A significant difference was observed for vitamin C intake (p < 0.05). The overall mean values of basic blood (WBC, RBC, Hct, and Hb), sex hormone (Estrogen, Progesterone), aldosterone, cortisol, Cu, Zn, and Ca, Mg indices in female college students were within the normal range and there was no significant difference between the PMS group and the Normal group. In conclusion, vitamin C intake of the PMS group showed a level of 84.8% EAR. Therefore vitamin C supplement can be beneficial to relieve the PMS Syndrome.
Aldosterone ; Ascorbic Acid ; Body Composition ; Calcium ; Ear ; Female ; Folic Acid ; Food Preferences ; Humans ; Hydrocortisone ; Phosphorus ; Premenstrual Syndrome ; Reference Values ; Vitamin A ; Vitamins

This study was performed to investigate nutritional intakes and preference food and blood composition of female college students of premenstrual syndrome. Based on physical measurement test results, both groups showed no noticeable difference and both groups were within the normal range according to body composition analysis. In terms of nutrients consumption, results showed nutritional intakes more than EAR (estimated average requirements) included phosphorus > vitamin B6>vitamin B1, while nutritional intakes less than EAR were vitamin A > vitamin B2> calcium > folic acid. A significant difference was observed for vitamin C intake (p < 0.05). The overall mean values of basic blood (WBC, RBC, Hct, and Hb), sex hormone (Estrogen, Progesterone), aldosterone, cortisol, Cu, Zn, and Ca, Mg indices in female college students were within the normal range and there was no significant difference between the PMS group and the Normal group. In conclusion, vitamin C intake of the PMS group showed a level of 84.8% EAR. Therefore vitamin C supplement can be beneficial to relieve the PMS Syndrome.
Aldosterone ; Ascorbic Acid ; Body Composition ; Calcium ; Ear ; Female ; Folic Acid ; Food Preferences ; Humans ; Hydrocortisone ; Phosphorus ; Premenstrual Syndrome ; Reference Values ; Vitamin A ; Vitamins

The serum concentrations of the major minerals(calcium, phosphorus, magnesium, sodium, potassium) and trace elements(iron, Zinc, copper manganese)were datermined in 23 breast fed infants living in Eumsung, Choong-buk region. The results obtained are summarized as follows: 1)The mean levels of calcium, phosphorus, magnesium, sodium and potassium of the serum of total subjects were 8.15+/-0.33mg/dI, 11.06+/-0.16mg/dI, 2.00+/-0.14mg/dI, 3.4476+/-17.99mg/dI and 9.06+/-2.04mg/dI respectively. 2)The serum concentrations of iron, zinc, copper and manganese in total subjects averaged 95.83+/-0.33mg/dI, 93.79+/-7.06 microgram/dI and 98.57+/-7.06 microgram/dI and 4.93+/-0.62 microgram/dI respecitively. 3)Breast fed infants had significantly higher serum calcim, magnesium, sodium and iron concentrations than the formula fed groups. Otherwise, serum potassium, copper and manganese levels in breast milk fed infants were significantly lower than those in formula fed infants. 4) In formula fed infants, serum potassium and copper levels increased increased significantly with months after birth.
Breast ; Calcium ; Copper ; Humans ; Infant* ; Iron ; Magnesium ; Manganese ; Milk, Human ; Minerals* ; Parturition ; Phosphorus ; Potassium ; Sodium ; Trace Elements* ; Zinc

OBJECTIVE: Adult onset Still s disease is an acute systemic inflammatory disorder. There are no pathognomonic symptoms or specific laboratory abnormalities. In recent reports, serum ferritin concentration is increased in active disease phase and decreased after defervescence. Our purpose was to determine the clinical significance of serum ferritin as an indicator for disease activity. METHODS: Seven patients who were diagnosed as adult onset Still s disease at Samsung Medical Center between October 1994 and March 1997, were reviewed. In these patients we checked leukocyte count, ESR, CRP and serum ferritin concentrations at the time of diagnosis and during follow-up periods and recorded febrile events during follow-up periods. RESULTS: At the time of diagnosis and during febrile periods, the concentrations of ferritin were extremely high(927ng/ml to 96,650ng/ml normal 10-290.8 ng/ml). The values were unrelated to other manifestations of the disease or laboratory findings. The ferritin concentrations decreased rapidly after adequate treatment. Eleven febrile reattacks happened in 7 patients. Serum ferritin concentrations were increased in 8 febrile attacks, while leukocyte count, ESR, and CRP were increased in 5, 5, 6 febrile attacks respectively, There were 10 events of increased serum ferritin concentrations in 7 patients during follow-up periods and 8 events were related with fever. The increases of other laboratory tests were similar. CONCLUSIONS: In all patients, serum ferritin concentrations were increased at the time of diagnosis and closely related to fever. During follow-up periods, serum ferritin concentrations are helpful in monitoring disease activity and guiding decisions about treatment.
Adult* ; Diagnosis ; Ferritins* ; Fever ; Follow-Up Studies ; Humans ; Leukocyte Count ; Still's Disease, Adult-Onset*

Intravascular injection of hydrogen peroxide produces oxygen microbubbles suitable for echocardiographic contrast enhancement. To evaluate the effect of a method of myocardial contrast 2-D-echocardiographic delineation of myocardium during acute coronary occlusion, injection of a fresh mixture of 2ml of 0.2% H2O2 and 1ml of heparinized dog blood into aortic root were made in 12 poenchest dogs 10 minutes after occlusion of left anterior descending coronary artery distal to the first diagonal branch and left ventricular short axis 2-D echocardiographic images at the midpapillary muscle level were obtained. On injection of H2O2 blood mixture normally perfused myocardium was enhanced in echodensity but the area of malperfusion did not change in echodensity. The borderlines between the area of normal perfusion and malperfusion was well delineated. The malperfused area measured at mid papillary muscle level by planimetry area method was 29.7+/-6.0% and 32.6+/-6.7% by endocardial circumferential length method. There was a linear correlation between planimetric estimate of area of malperfusion by H2O2 contrast echocardiography and visual determination of regional wall motion abnormality by 2-D echocardiography(r=0.93, P<0.001). There was no change in heart rate before, during and after H2O2 injection. Infection of H2O2 blood mixture caused bradycardia(8.3%), second degree A-V block(16.6%) and ventricular fibrillation(8.3%). H2O2 clearance was achieved in 3-10 minutes. These findigs suggest that H2O2 enhanced myocardial contrast ehocargiography using 2ml of 0.2% H2O2 and 1ml of blood muxture is an accurate, reproducible, real-time in vivo method of quantifying the extent of myocardial perfusion defect during acute coronary occlusion in dog.
Animals ; Axis, Cervical Vertebra ; Coronary Occlusion ; Coronary Vessels ; Dogs* ; Echocardiography* ; Heart Rate ; Heparin ; Hydrogen Peroxide* ; Hydrogen* ; Microbubbles ; Myocardium ; Oxygen ; Papillary Muscles ; Perfusion*

The purpose of this study was to assess the maternal zinc status during pregnancy and to evaluate the relationship between the zinc concentration of maternal, umblical cord blood and placental tissue and pregnancy outcomes. Venous blood samples were drawn from 53 pregnant women just before delivery and the cord blood of their newborn babies was collected immediately after birth. In addition, placental tissues were extracted. We investigated the difference in the concentration of zinc in maternal, umbilical cord blood and placental tissue in two gestational age groups (preterm delivery group [PT] and normal term delivery group [NT]) at 34.7 wk and 39.0 wk of mean gestational age, respectively). We also assessed correlations of the zinc concentration of maternal, umbilical cord blood and placental tissue. Lastly, we studied the correlations between the birth weights and the zinc concentration in the maternal, umbilical cord blood and placental tissue. The concentrations of maternal serum zinc and of umbilical cord serum zinc were significantly higher in the PT group (76.9 +/- 37.4 microgram/dl, 101.3 +/- 41.4 microgram/dl) than in those of the NT group (57.8 +/- 22.4 microgram/dl, 80.7 +/- 27.5 microgram/dl), respectively (p < 0.05). The zinc concentration of the umbilical cord blood was significantly higher than that of the maternal blood in both groups (p < 0.05). There was no significant correlation between the gestational age and the serum zinc concentration in the cord or the maternal serum. Our results showed that there was a negative relationship between the birth weight (r = -0.286) and the maternal serum zinc concentration. Despite there not being a significant difference, there was tendency for the highest concentrations of maternal serum zinc to be associated with the lowest birth weights. These findings support a possible relationship between the maternal zinc status and the pregnancy outcome, and suggest that zinc may play a role in the many biological processes involved in the successful outcome of a pregnancy.
Biological Processes ; Birth Weight* ; Female ; Fetal Blood ; Gestational Age ; Humans ; Infant, Newborn ; Parturition* ; Placenta* ; Pregnancy ; Pregnancy Outcome ; Pregnant Women ; Umbilical Cord* ; Zinc*

The purpose of this study was to evaluate the nutritional status and growth of Korean infants, who were atending peripheral community clinics in low income areas, by anthropometric measurements and estimating dietary intakes. Dietary intakes and growth were compared among different feeding patterns of 143 infants until age 9 months. The overall mean nutrient intakes of infants in this study were below the recommended allowances except the calcium intake from significant difference in each groups; however, calcium, zinc and iron intake of the formula fed infant(FF) was higher than the breast fed infant(BF) or the mixed fed infant(MF). Form ages 4-6 months, the nutrient intakes were shown to be higher in groups that were given supplementary foods than groups that were not. From ages 7-9 months, all nutrient intakes were higher in or the formula and supplementary foods fed(ESF) infants than in the breast and supplementary food(BSF) or the formula and supplementary food(FSF) groups, All subjets in this study showed a large Z-score. The growth of infants up to 6 months of age showed no significant difference in the feeding pattern, however, after 7 months of age the BSF group had significantly lower weight than the FSF or the ESF groups, There were significant positive relationships between infants weight gain at age 7-9 months from birth and the current protein or zinc intakes. As a result the average status of nutrient intakes of infants in this area was loser than the RDA, however, the growth pattern was fairly good. Although the breast milk is beneficial for infants, mothers should be educated for the importance of supplemental food and its practice to support good nutrition.
Breast ; Calcium ; Feeding Behavior ; Humans ; Infant ; Iron ; Milk, Human ; Mothers ; Nutritional Status ; Parturition ; Weight Gain ; Zinc

The major purpose of this study was to develop the nutrition education contents and material through the basic data from the service provider and the consumer. And also, to find out the differences of attitude and needs between the service provider (SP, breastfeeding specialist), present consumer (PC, pregnant or lactating women) and future consumer (FC, college women). There were types of questionnaires, which consisted of needs and attitudes toward child and maternal nutrition, as well as the personal characteristics of the study subjects. The subjects consisted of 113 breastfeeding specialists who served at medical related institutions, 197 pregnant or lactating women and 309 college women. The self-administered questionnaires from subjects were collected from October to November 2005 in Seoul and Kyunggi Province. The data was analysed by SPSS Win 12.0, ANOVA and Kruskal-Wallis test. The results of this study were as following: 1) The most important determining factors on breastfeeding was 'medical specialist's support' (3.51) and the next one was 'knowledge of maternity care practice' (3.39). And the importance score of determinating factors on breastfeeding was significantly different between each group (p<0.001). The groups of consumer (3.50 at PC and 3.59 at FC) considered the service provider (3.32) more important. The service providers considered a more effective determining factor to be "husband and family support" and "peer support" than the others (p<0.001). 2) To compare the effective factors of breastfeeding practices between the three groups, the service providers were more significantly considered than the others such as "attendance of intervention program" (p<0.001). But the PC group considered the most effective factors was "mother's job after delivery". 3) The self-evaluated score of the breastfeeding knowledge was the most high in SP; the score was significantly different between groups. The knowledge score of nutritional aspects in human milk was most highly evaluated. But maternity care practice and public acceptance marked the lower evaluation score than other issues. 4) The desirable types of educational material was mass media, and the next was printed matter such as booklets. Two kinds of consumers preferred DVD or VCR tapes than and the service provider group (p<0.001). 5) The priority contents of nutrition service PC group wanted the information about infant care more than maternal care (p<0.05), but FC group's priority was significantly different compared with PC group (p<0.001). The priority of SP group pointed out the information of practical child care methods. The results showed the needs of nutrition service, education channels, and perception toward effective factors on consumer behavior changes were significantly different between each group. Thus the result of this study may suggest that consumer oriented nutrition service programs must be developed.
Breast Feeding ; Child ; Child Care ; Education* ; Female ; Gyeonggi-do ; Humans ; Infant ; Infant Care ; Mass Media ; Milk, Human ; Pamphlets ; Seoul ; Specialization*

No abstract available.
Child* ; Hemorrhagic Fever with Renal Syndrome* ; Humans