1.Understanding the regulation of AIDS prevention and management
Chinese Journal of Laboratory Medicine 2003;0(07):-
"PRC Law on HIV/AIDS Prevention and Control" came into force on March 1, 2006. According to the law, iatrical workers should take every patient and sample as infected ones to assure iatrical biosafety and should not discriminate against people living with HIV/AIDS. HIV/AIDS patients have the right to accept therapy in hospitals and iatrical workers were not allowed to refuse them by using any reason. If the law was not well performed by iatrical workers, they will be punish and even accept penal punishment. Iatrical workers should act as the rules stated by the law and know the rights and incumbencies to provide the stable foundation for the prevention and treatment of HIV in our country.
2.The situation of HIV prevalence,testing and treatment in China
Chinese Journal of Laboratory Medicine 2008;31(10):1088-1090
The HIV/AIDS epidemic in China has entered the Widespread Epidemic Period.HIV-infected cases have been reportedly found in all 34 provinces(minority autonomous regions/municipalities).HIV is spreading from high risk group to general population.Our government has paid much attention to AIDS prevention and control,lots of effective measures have been carried out,and comprehensive prevention.treatment,bealth care and financial support have been launched.Relatively consummate surveillance system and laboratory testing network of AIDS have been established at present and large SCale of ARTs have been carried out through the whole country.There is a great change in the situation on AIDS Prevention and Control in China.
3.EFFECT OF PCEA ON THE SERUM ENDOTHELIN AND THE RENAL FUNCTION AFTER OPERATION IN KIDNEY TRANSPLANTATION PATIENTS
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
To observe the effect of PCEA on the serum endotheline and the renal function after operation in kidney transplantation patients. Forty patients with chronic renal failure were randomly divided into two groups: group P( n =20) and group N ( n =20) .Venous blood samples were drawn before anesthesia at the end of operation and 24, 48, 72h after operation. Mean arterial pressure (MAP), serum endothelin,creatinine, urea nitrogen, uric acid were measured with radioimmunoassay. The results showed that the MAP, serum endothelin, creatinine, urea nitrogen and uric acid were decreased significantly at 24h after operation.All of them reached the nadir at 72h after operation. But those of group N were significantly higher than group P ( P
4.One case of XG501A X-ray machine breakdown repair
China Medical Equipment 2013;(11):130-130,131
It reports the E02 breakdown after XG501A program controller starting. The experiences and solutions of the E02 breakdown. According to the breakdown prompt, we carry on the analysis and the overhaul to the gastrointestinal filament preheating circuit. It is able to find the breakdown surely to be at, if you carried on the analysis search according to electric circuit's work flow. You must consider that comprehensive and gradually metrical data in the overhaul process. You cannot take for granted and only then may avoid detouring and equipment's damage.
5.Single nucleotide polymorphisms and haplotypes of MBL gene in Han and Hui ethnic children of Han and Hui ethnics
Hong WANG ; Chunzhen HUA ; Shiqiang SHANG
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
Objective To analyze the single nucleotide polymorphisms(SNPs) in promoter region,5' untranslated region,exon 1 and haplotypes of mannose binding-lectin(MBL) gene in Han nationality and Hui etheic children in China.Methods Sixty nine Hui ethnic children from Ningxia Huizu Auto.Reg.and 105 Han children from Zhejiang Prov.were enrolled in the present study.Whole blood samples(1.5 ml) were collected into potassium-EDTA tubes.SNPs in promoter region,5' untranslated region and exon 1 of MBL gene were determined by sequence analysis using BigDye Mix 3730 genetic analyzer,and genetic analysis was performed using SHEsis software.Results The variant allele frequencies at-221 sites in Han and Hui objects were 0.091 and 0.123,respectively,with no difference between the two groups(?2=0.684,P=0.408).No mutation was found at sites +223 and +239 in exon 1 of MBL gene in the study.The variant frequency at +230 site in Hui children(0.268) was significantly higher than that in Han objects(0.167,?2=5.223,P=0.022).The most common haplotype was YA,and the frequencies of YA haplotype in Han and Hui ethnic were 0.770 and 0.669,respectively,with significant difference between the two groups(?2=4.312,P=0.038).Conclusion The variant allele frequency at +230 sites in exon 1 in Hui ethnic children is higher than that in Han subjects.The most common haplotype is YA,and the frequency of YA haplotype is higher in Han children than that in Hui subjects.
6.EXPRESSION OF CD_(15)AND CATH-D IN ENDOMETRAL ADENOCARCINOMA AND ITS CLINICAL SIGNIFICANCE
Huaping GU ; Peizhong SHANG ; Hong SU
Cancer Research and Clinic 2000;0(01):-
Objective:To investigate the relationship between the expression of CD 15 antigen and Cath-D carcinogenesis,progression and metastasis of endometral carcinoma.Methods:The expression of CD 15 and Cath-D in 40 cases of endometral adenocarcinoma was detected by SP immunohistochemical technique.Results:The positive rates of CD 15 and Cath-D were 72.5% and 67.5% respectively.CD 15 was correlated with the histologic grading and clinical staging of endometral adenocarcinoma (P
7.Induced abortion in China: problems and interventions.
Acta Academiae Medicinae Sinicae 2010;32(5):479-482
Pooled literatures showed that the induced abortion in China faces many problems:the number of induced abortion remains large; most cases are young and nulliparity women; the frequency of abortion is high; and the interval between one and another abortion is short. Health promotion strategies should be applied to address these problems. It is important to increase the population's awareness of contraception,especially among nulliparity and migrant populations. Routine and effective contraceptive methods should be recommended and emphasized during induced abortion and delivery to lower the rate of induced abortion.
Abortion, Induced
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statistics & numerical data
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China
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Female
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Humans
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Pregnancy
8.Human follicular dendritic cells increase HIV infection
Yongjun JIANG ; Hong SHANG ; Yanan WANG ;
Chinese Journal of Immunology 2000;0(08):-
Objective:Study on the possibility that human follicular dendritic cells(FDC) can increase HIV infection and to investigate the related mechanisms.Methods:Human FDC was isolated from tonsils and cultured with infected heterogenous pheripheral lymphocytes or cultured with infected hemogenous tonsilar T lymphocytes.HIV P24 antigen,HIV 1 env DNA and HIV 1 nef RNA were determined respectively with ELISA method,PCR or RT PCR method.Results:FDCs were cultured with infected heterogenous lymphocytes,the P24 antigen is 6 7 times higher than the control group(P
9.Influence of coix seed triglyceride combined with transcatheter arterial chemoembolization therapy on the immune function in patients with advanced primary hepatocellular carcinoma
Hong-ye SHANG ; Mao YANG ; Hui GUO
Journal of Interventional Radiology 2015;(9):807-810
Objective To investigate the influence of coix seed triglyceride combined with transcatheter arterial chemoembolization (TACE) therapy on AFP, CD4﹢CD25﹢regulatory T (Treg) cells and cellular immune function in patients with advanced primary hepatocellular carcinoma (HCC). Methods A total of 50 patients with inoperable HCC, whose imaging examination showed no distant metastasis, were divided into the study group (n=25) and the control group (n=25). Coix seed triglyceride together with TACE was employed for the patients of the study group, while only TACE was adopted for the patients of the control group. For the patients of the study group, transcatheter hepatic artery infusion of 100 ml coix seed triglyceride was carried out during the performance of TACE, and postoperative intravenous drip of coix seed triglyceride (200 ml/d) was used for 5 days. The peripheral blood samples were collected one week before and one month after the treatment to detect the changes of AFP and T lymphocyte subsets (CD3﹢, CD4﹢, CD8﹢,CD4﹢/CD8﹢ and Treg) levels. One month after the treatment, enhanced CT, MRI or PET-CT was performed to evaluate the necrosis degree of the tumor. Results After the treatment, AFP levels was decreased in both groups, when compared the preoperative data the differences were statistically significant (P<0.01); the tumor necrosis rate of the study group was (57.7 ±8.2)%, which was slightly higher than (57.7±8.2)% of the control group, however, the difference was not statistically significant (P>0.05). In the study group, the percentage of Treg cells decreased from preoperative (8.27±6.65)%to postoperative (4.22± 1.59)%, the difference was statistically significant (P<0.01). The percentages of CD3﹢ and CD4﹢ and the ratio of CD4﹢/CD8﹢ increased from preoperative (55.78 ±13.66)%, (43.98 ±14.00)% and 1.22 ±0.64 to postoperative (62.29±10.78)%(P<0.01),(51.82±16.32)% (P<0.05) and 1.54±0.80 (P<0.05) respectively, while the percentage of CD8﹢decreased from preoperative (45.71±12.94)%to postoperative (39.70±12.41)%(P<0.05). In the control group, no statistically significant differences in the above mentioned indexes existed between preoperative data and postoperative ones (P>0.05). Conclusion In treating advanced primary HCC, coix seed triglyceride combined with TACE can reduce the percentage of Treg cells, thus, influence the patient’s cellular immune status and possibly decrease the recurrence rate of HCC after TACE therapy.
10.On How to Teach the Obstetrics and Gynecology for the Seven-year Program Medical Students
Yuhong SHANG ; Hong SHI ; Hong YE ; Juan FU
Chinese Journal of Medical Education Research 2003;0(02):-
The Department of Obstetrics and Gynecology has performed series of teaching reforms for the seven-year medical students.For the theory classes,all the teachers are the senior ones who can enhance the bilingual teaching and combine the clinical cases with the latest development in the subject.We let the interns follow the diagnosis and treatment of the patients just as the patients'relatives.We also let a tutor to guide each intern to help him master the basic clinical art.During the ward inspection for teaching,we let the students be the main speaker,hoping that we can build a new student-centered teaching model.