A clinical observation was performed on 154 cases of chronic prostatitis in the Department of Urology, National Seoul Hospital from January 1981 to March 1982. The results are as follows: 1. 121 cases or 78.4 percent of the cases were observed among the ages between 20 to 40 years are more than one half of these cases were seen between the ages of 26 to 35 years. 2. Previous diseases were Non-gonococcal urethritis on 82 cases (53.2%), Gonococcal urethritis on 45 cases(29.2%) and previous prostatitis on 15 cases (9.7%). 12 cases (7.8%) were free of previous diseases. 3. Most frequently observed symptoms consisted of those of mild chronic urethritis such as morning drop, urethral discomfort, perineal discomfort and frequency. 4. In microscopic findings of wet smear of the prostatic secretion, 125 cases (81.2%) showed W.B.C. more than10/H.P,F. 29 cases (18.8%) were within normal limit. 5. In 125 cases in which prostatic gram stain was done, microorganisms were gram (+) cocci on 26 cases (20.8%),gram (-) bacilli on 12 cases (9.6%) and gram (+) bacilli on 10 cases (8.0%). No microorganism were on 77 cases (61.6%).
Prostatitis* ; Seoul ; Urethritis ; Urology

No abstract available.
Korea* ; Metabolism, Inborn Errors*

No abstract available.
Thyroid Diseases* ; Thyroid Gland*

No abstract available.
Child* ; Dinitrochlorobenzene* ; Humans ; Immunotherapy* ; Warts*

Pretibial myxedema, which consists of localized cutaneous accumulations of acid mucopolysaccharides, oceurs in a few patients with hyperthyroidi';m after its correction by surgery or radioactive iodine therapy. We report a case of pretibial myxedema with exophthalmos in a 36 year old male. He has suffered from hyperthyroidism with bilateral pretibial myxedema for a period of 4 years. He was treated with a subtotal thyroidectomy and excision of both pletibia lesions 1 year ago. The lesions recurred on t,he left pretibial area, as a 11 X 16cm sized, non pitting, non tender, swollen, brownish plaque. The histopathologic findings showed epidermal hyperkeratosis and a considerable arnount of mucin in the mid-dermis. We treat.ed him with intralesional injection of triamcinolone acetonide with marked improvement.
Adult ; Exophthalmos ; Glycosaminoglycans ; Humans ; Hyperthyroidism ; Injections, Intralesional ; Iodine ; Male ; Mucins ; Myxedema* ; Thyroidectomy ; Triamcinolone Acetonide

No abstract available.
Immunologic Tests* ; Tuberculosis, Meningeal*

Ultrasonographic localizations were performed by methylene blue injection in 35 cases of nonpalpable breast lesion. The lesions were sized 0.3cm-1.3cm and biopsied just after localization with 100% success rate. All the patients tolerated well the procedure and had not any complications. Ultrasonoguided dye injection is an accurate, comfortable and simple method for prebiopsy localization of nonpalpable breast lesion.
Breast* ; Humans ; Methylene Blue

BACKGROUND: Pregnancy in human and rodents is associated with dramatic matemal metabolic changes. Insulin-like growth factors (IGFs) are mitogenic peptides that are essential for fetal and maternal tissue growth during pregnancy. They circulate complexed primarily with a serum IGF-binding protein (IGFBP-3) which regulates the availability of the IGFs to their specific target tissues. METHODS: To examine the changes of IGFs and IGFB-3 during pregnancy, we measured serum total IGF-I, free IGF-I, IGF-II and IGFBP-3 by using specific radioimmunoassay, immunoradio-metric assay, western ligand blot and western immunoblot. Blood samples were obtained from 88 pregnant women between 6-40 weeks gestation. RESULTS: While serum IGF-I levels increased up to 50% in late pregnancy, serum IGF-II levels remained unchanged. However, serum free IGF-I levels were significantly higher during pregnancy than in nonpregnancy. Western ligand blot analysis revealed that IGFBP-3 in pregnancy serum was significantly decreased at 6 weeks of gestation, continued decreased level until term, and returned to a nonpregnant level by postpartum 10 day. Serum IGFBP-3 profiles in Western immunoblot analysis revealed that 30 kDa fragments of IGFBP-3 were detectable in pregnancy serum but not in nonpregnancy serum. In contrast, serum IGFBP-3 levels using radioimmunoassay was significantly increased in late pregnancy. CONCLUSIONS: 1) serum IGF-I was significantly elevated in late pregnancy 2) serum IGF-II was not significantly changed 3) free IGF-I significantly elevated throughout gestation 4) intact IGFBP-3 was markedly reduced after 6 weeks of gestation.
Blotting, Western ; Female ; Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor I ; Insulin-Like Growth Factor II ; Peptides ; Postpartum Period ; Pregnancy* ; Pregnant Women ; Radioimmunoassay ; Rodentia ; Somatomedins

Malignant melanoma is an uncommon tumor in Korea. To the best of our knowledge, we could not find malignant melanoma with multiple myeloma in Korean literature. A 57-year-old male patient had a 4×5 cm sized, irregular bordered, dark brownish plaque on the left sole, which has extended gradually since about 1 year ago and showed an occasional bleeding tendency. Laboratory examinations revealed a low hemoglobin level, rouleaux formation on peripheral blood, monoclonal gammopathy of IgG-kappa type and Bence-Jones proteinuria. Bone marrow aspiration findings showed markedly increased immature plasma cells suggesting multiple myeloma. Histopathologic findings of the skin biopsy from the left sole revealed proliferation of atypical melanocytes. We performed a surgical excision with a skin graft for malignant melanoma and chemotherapy (melphalan, vincristine and prednisolone) for multiple myeloma.
Biopsy ; Bone Marrow ; Drug Therapy ; Hemorrhage ; Humans ; Korea ; Male ; Melanocytes ; Melanoma* ; Middle Aged ; Multiple Myeloma* ; Paraproteinemias ; Plasma Cells ; Proteinuria ; Skin ; Transplants ; Vincristine

A clinical observation was made on 25 patients of cryptorchism who had been admitted to the Department of Urology, National Seoul Hospital during the 3 years period from January, 1979 to December, 1981. The following results were obtained: 1. The most frequent age group was seen at over 15 and average age was 11.2 years which means too late for requiring adequate treatment. 2. Orchiopexy was performed on 28 testis (84.9%), 4 cases were performed the orchiectomy because of atrophy or impossible placement to scrotum and histopathology revealed atrophic change, in all removed testes. 3 cases among them were proved to oligo-azoospermia by semen analysis. 3. The bilateral cryptorchisms were observed in 8 cases (32%)and inguinal type in 20 (60.6%), prepubic type in 6 (18.2%), intra-abdominal type in 4 (12.1%)and superficial inguinal type in 2 (6.1%) (12 cases in right and 5 cases in left). 4. Associated anomalies and complications were found in 11 cases (44%)and the most common anomalies were hernia, which was found in 4 cases (15.2%).
Atrophy ; Cryptorchidism* ; Hernia ; Humans ; Male ; Orchiectomy ; Orchiopexy ; Scrotum ; Semen Analysis ; Seoul ; Testis ; Urology