3.Clinical study of Buerger's disease, based on angiogram.
Lee Su KIM ; Young Chul LEE ; Hong Rae CHO ; Song KIM ; Won Jin CHOI
Journal of the Korean Surgical Society 1992;43(2):258-265
No abstract available.
Thromboangiitis Obliterans*
4.A case of glomus tympanicum.
Ki Hong CHANG ; Rae Sung PARK ; In Ja LEE ; Byung Do SUH
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(5):1065-1068
No abstract available.
Glomus Tympanicum*
5.Three Cases of Renal Infarction.
Moon Wen LEE ; Man Soo LEE ; Seung Rae CHO ; Hong Yong CHOI ; Kwang Soo LEE
Korean Journal of Urology 1996;37(12):1404-1408
Renal Infarction is a rare disease and in 90% of patients with renal infarction, underlying cardiac disease is presented. Most often this includes valvular heart disease, cardiac arrhythmias, rheumatic heart disease with fibrillation, or subacute bacterial endocarditis. The correct clinical diagnosis and appropriate treatment of renal infarction are often delayed. Three cases of renal infarction were presented with review of literature.
Arrhythmias, Cardiac
;
Diagnosis
;
Endocarditis, Subacute Bacterial
;
Heart Diseases
;
Heart Valve Diseases
;
Humans
;
Infarction*
;
Rare Diseases
;
Rheumatic Heart Disease
6.Screening of Anti-HIV-1 Activity of Natural Product by MTT Assay.
Joo Shil LEE ; Jeong Gu NAM ; Chun KANG ; Hong Rae LEE ; Young Jong LEE ; Yung Oh SHIN
Journal of the Korean Society of Virology 1997;27(1):87-95
Methanol and/or boiling water extraction of 201 natural products and subsequent MTT assay using MT-4 cell line was carried out to screen the anti-HIV-1 activity. Among 97 methanol extracts, 7 extracts from Chrysanthemi Indicium Flos, Magnoliae Cortex Machili Cortex, Reynoutriae Rhizoma, Lithospermi Radix Agastachis Herba, and Chaenomelis Fructus showed anti-HIV-1 activity and their SI value were 2.25 to 5.77. In addition, among 119 boiling water extracts, 10 extracts from Lonicerae Caulis et Foloium, Elsholtziae Herba, Leonuri Herba, Portulacae Herba, Schizonepetae Herba, Curcumae Rhizoma, Amomi Cardamomi Fructus, Cirsii Radix et Herba, Carpesii Herba, and Siegesbeckiae Herba showed anti-HIV-1 activity and their SI value were 1.30 to 7.64. Methanol extracts of above seven natural products were fractionated and the anti-HRs_1 activity of each fraction was examined. Extraction was carried out with hexane, chloroform, butanol, and water to trace active anti-HIV-1 componets. As a result, the water fraction of Magnoliae Cortex, Machili Cortex, Reynoutriae Rhizoma, Agastachis Herba, Chaenomelis Fructus and the butanol fraction of Chrysanthemi Indicium Flos, Reynoutriae Rhizoma showed anti-HIV-1 activity and their SI value were 1.40 to 8.02. We could reach a conclusion that studies to trace the anti-HIV-1 active component of each natural products in further Sractionation and to identify its structure by Infrared spectroscopy, NMR spectroscopy and gel permeation chromatography were needed.
Biological Products
;
Cell Line
;
Chloroform
;
Chromatography, Gel
;
Curcuma
;
Lamiaceae
;
Lithospermum
;
Lonicera
;
Magnetic Resonance Spectroscopy
;
Magnolia
;
Mass Screening*
;
Methanol
;
Portulaca
;
Spectrum Analysis
;
Water
7.Isolation and Identification of Herpes Simplex Virus Type 2 from Patients with Herpes Progenitalis.
Yung Oh SHIN ; Chun KANG ; Hong Rae LEE ; Sang Yun NAM ; Chung Won KIM ; Nam Soo HONG
Korean Journal of Dermatology 1989;27(1):34-38
In the present study, we have tried to isolate and identify herpes simplex virus type 2(HSV 2) from clinical specirnens, which were inoculated into Vero cell line and grown. Eight strains of viruses were isolated from 20 suspected cases diagnosed from the pr ivate clinics in Seoul. Viruses isolated from 4 rnale and 1 female cases with active lesion were identified to the HSV 2 by indirect immunofluorescence using monoclonal antibody to HSV-2. In addition, morphology of the isolated viruses were observed under electron microscope.
Female
;
Fluorescent Antibody Technique, Indirect
;
Herpes Simplex*
;
Herpesvirus 2, Human*
;
Humans
;
Seoul
;
Simplexvirus*
;
Vero Cells
8.A Case of Spontaneous Perirenal Hematoma due to Metastatic Choriocarcinoma to the Perirenal Fat.
In Rae CHO ; Young Deuk CHOI ; Sung Joon HONG ; Young Tae LEE ; Soon Won HONG
Korean Journal of Urology 1990;31(4):600-605
Spontaneous perirenal hematoma can occur during the course of a varied group of diseases. It is not a rare disease. The diagnosis is based on either the sudden or insidious onset of abdominal or flank pain, abdominal distention, the symptoms and signs of internal bleeding, and the appearance of a mass in either upper quadrant. The picture of the acute surgical condition of the abdomen is often seen. The treatment is surgery and prognosis depends upon the underlying disease, the degree of hemorrhage and the promptness of treatment. We experienced one case of spontaneous perirenal hematoma due to metastatic choriocarcinoma only to the perirenal fat, not renal parenchyme.
Abdomen
;
Choriocarcinoma*
;
Diagnosis
;
Female
;
Flank Pain
;
Hematoma*
;
Hemorrhage
;
Pregnancy
;
Prognosis
;
Rare Diseases
9.Study on the Zidovudine Resistance of HIV-1 Isolated Strains in Korea.
Jeong Gu NAM ; Chun KANG ; Joo Shil LEE ; Hong Rae LEE ; Dong Yun SHIN ; Yong Keun PARK ; Yung Oh SHIN
Journal of the Korean Society of Virology 1997;27(1):77-86
To examine AZT resistance of HIV-1 isolates from AZT treated or untreated Korean, several biological characteristics such as syncytium formation, HIV-1 reverse transcriptase activity and the p24 antigen production in MT-2 cells infected with 4 HRT_1 isolates were determined. As controls, we tested HIV-1 HTLV-IIIB and pre-drug isolate as AZT susceptible strains, in addition to HIV-1 RTMC/MT-2 and post-drug isolate as AZT resistant strains. When the inoculum size of HIV-1 was 300 TCID50well and 100 TCID50/well, the AZT susceptibility of AZT untreated HIV-1 isolates 8806 and 9571 were similar to that of HIV-1 HTLV-IIIB and AZT-susceptible HIV-1 strains. When we evaluated AZT resistance of isolates HRs-1 8812 and 9113 treated with AZT for 36 months by observation of syncytium formation, HIV-1 8812 showed resistance simillar to that of HIV-1 RTMC/MT-2 strain forming syncytium up to AZT 1microgram/ml, and HIV-1 9113 showed resistance identical with that of AZT-resistant HIV-1 strain which formed syncytium up to AZT 10 microgram/ml. Especially, when we evaluated AZT resistance by HIV-1 reverse transcriptase activty and the p24 antigen production, HIV-1 isolates 8812 and 9113 showed much higher resistance (>10 - 200 fold) compared with HN-1 RTMC/MT-2 and AZT-resistant HIV-1 strain.
Giant Cells
;
HIV-1*
;
Korea*
;
Population Characteristics
;
RNA-Directed DNA Polymerase
;
Zidovudine*
10.Psychiatric Evallution of Alopecia Ateata.
Youn Rae PARK ; Dong Un KIM ; Cheol Heon LEE ; Hong Jig KIM ; Chang Jo KOH ; Baik Kii CHO
Korean Journal of Dermatology 1981;19(2):161-165
One hundred and seven patients with alopecia areata were studied in regard to the character of personality, emotional stress during their military life, socioeconomic status and their possible role in the pathogenesis of alopecia areata by ready-made chart and Minnesota Multiphasic Personality Inventory (M.M.P.I,) While only 55. 4% of out patients were enlisted men, 73. 0% of alopecia areata patients were soldiers suggesting that soldiers are more prone to develop alopecia areata. This trend was more apparent among soldiers who were less than 6 months in the service. In clinical scale, abnormal MMPI profiles were noted in 65 patients (60. 7%). Among abnormal MMPI profiles, hysteria scale is most common (23. 1%) and followed by hypochondriasis scale 18. 5%, psychiasthenia scale 16. 9%, and paranoia scale 12. 3%. The alopecia areata group showed significant difference in psychopathic deviate, schizophrenia, and paranoia which is high in person having psychotic symptoms and psychopathic personality. The neurotic triad or anxiety index is not significantly elevated.
Alopecia Areata
;
Alopecia*
;
Antisocial Personality Disorder
;
Anxiety
;
Humans
;
Hypochondriasis
;
Hysteria
;
Male
;
Military Personnel
;
MMPI
;
Outpatients
;
Paranoid Disorders
;
Schizophrenia
;
Social Class
;
Stress, Psychological