1.The secular trend of menarcheal age in Korea.
Chang Ho HONG ; Hyung Rae CHO ; Kye Suk PARK
Journal of the Korean Pediatric Society 1993;36(2):239-243
The age of puberty represents a very critical time in the life history of every young woman. The menarche stands as primary indicator of the onset of sexual maturation in females. According to several studies, menarcheal age in Korean girls has dropped from about 15 years of age in 1960s to 13.5 years of age in 1980s. This findings show a pronounced secular trend to earlier maturation. The purpose of this study is to determine (1) the average age at menarche in Korea in present time, (2) the secular trend of menarcheal age, and (3) the geographic regional influence on menarche. The data sampling was obtained from the physical examination cards of women students in Yonsei University who entered from 1983 to 1991. The data which was obtained from the number of 7761 was analysed by dBase III plus and SAS program. The results are as follows: 1) The mean menarcheal age of the subjects was 13.7+/-1.2 years. 2) Age at menarche has been getting earlier by some 7.4 months during the period of recent II years. 3) Comparing to the decreasing secular trend of menarcheal age, the height and weight showed increasing trend. 4) There were significant differences in menarcheal age, height, weight among geographic regions. We conclude that the results indicate an accelerating secular trend in age of menarche in Korea.
Adolescent
;
Female
;
Humans
;
Korea*
;
Menarche
;
Physical Examination
;
Puberty
;
Sexual Maturation
2.Clinical study of Buerger's disease, based on angiogram.
Lee Su KIM ; Young Chul LEE ; Hong Rae CHO ; Song KIM ; Won Jin CHOI
Journal of the Korean Surgical Society 1992;43(2):258-265
No abstract available.
Thromboangiitis Obliterans*
3.A Case of Spontaneous Perirenal Hematoma due to Metastatic Choriocarcinoma to the Perirenal Fat.
In Rae CHO ; Young Deuk CHOI ; Sung Joon HONG ; Young Tae LEE ; Soon Won HONG
Korean Journal of Urology 1990;31(4):600-605
Spontaneous perirenal hematoma can occur during the course of a varied group of diseases. It is not a rare disease. The diagnosis is based on either the sudden or insidious onset of abdominal or flank pain, abdominal distention, the symptoms and signs of internal bleeding, and the appearance of a mass in either upper quadrant. The picture of the acute surgical condition of the abdomen is often seen. The treatment is surgery and prognosis depends upon the underlying disease, the degree of hemorrhage and the promptness of treatment. We experienced one case of spontaneous perirenal hematoma due to metastatic choriocarcinoma only to the perirenal fat, not renal parenchyme.
Abdomen
;
Choriocarcinoma*
;
Diagnosis
;
Female
;
Flank Pain
;
Hematoma*
;
Hemorrhage
;
Pregnancy
;
Prognosis
;
Rare Diseases
4.Massive gastrointestinal hemorrhage from the colonic varices: report of 1 case.
Chang Yong SONG ; Young Cheol LEE ; Hong Rae CHO ; Dong Kun KIM ; Sung KIM ; Won Jin CHOI ; Hye Rim PARK
Journal of the Korean Surgical Society 1993;44(6):923-928
No abstract available.
Colon*
;
Gastrointestinal Hemorrhage*
;
Varicose Veins*
5.Roles of IL-33 in Resistance and Tolerance to Systemic Candida albicans Infections.
Sang Jun PARK ; Hong Rae CHO ; Byungsuk KWON
Immune Network 2016;16(3):159-164
IL-33 is a multifunctional cytokine that is released in response to a variety of intrinsic and extrinsic stimuli. The role of IL-33 in Candida albicans infections is just beginning to be revealed. This cytokine has beneficial effects on host defense against systemic C. albicans infections, and it promotes resistance mechanisms by which the immune system eliminates the invading fungal pathogens; and it also elevates host tolerance by reducing the inflammatory response and thereby, potentially, tissue damage. Thus, IL-33 is classified as a cytokine that has evolved functionally to protect the host from damage by pathogens and immunopathology.
Candida albicans*
;
Candida*
;
Immune System
;
Interleukin-33*
6.Clinical Strategies to Develop Transplantation Tolerance.
Jong Soo LEE ; Byungsuk KWON ; Hong Rae CHO
Hanyang Medical Reviews 2006;26(3):70-76
The development of immunosuprressants has had a significant influence on inhibition of acute allograft rejection. However, long-term graft survival has not been achieved by immunosuppressants, probably because of their nonspecific suppression of T cell activity and nonimmune side effects. The ideal way to overcome the limitations of current immunosuppressants is to induce allograft-specific immune tolerance. Transplant immunologists are exerting their efforts in achieving transplantation tolerance using four different approaches; costimulatory blockade, mixed hematopoietic chimerism, T cell depletion, and regulation by regulatory T cells. It is expected that transplantation tolerance will soon be established as a standard immunosuppressive regimen with little side effects in preventing and reversing allograft rejection.
Allografts
;
Chimerism
;
Graft Survival
;
Immune Tolerance
;
Immunosuppressive Agents
;
T-Lymphocytes, Regulatory
;
Transplantation Tolerance*
7.Renal transplantation in CsA-treated patients aged 50 years and older.
Yong Shin KIM ; Ku Yong CHUNG ; Yu Seun KIM ; Kun Kon KO ; Hong Rae CHO ; Kiil PARK
The Journal of the Korean Society for Transplantation 1992;6(1):47-53
No abstract available.
Humans
;
Kidney Transplantation*
8.Clinical Analysis of Diverticulosis of the Cecum and Ascending Colon.
Gyu Yeol KIM ; Chang Woo NAM ; Byung Kyun KO ; Hong Rae CHO ; Chan Jin PARK ; Dae Hwan CHOI
Journal of the Korean Society of Coloproctology 1998;14(3):595-604
BACKGROUND: Diverticulosis of the cecum and ascending colon is a rare disease in Western countries, it is more common in the Orient. Making the diagnosis preoperatively could be difficult, and the intraoperative assessment and decision of optimal treatments are difficult. METHODS: Therefore, we reviewed the patient's charts of diverticulosis of the cecum and ascending colon at our hospital from 1992 to 1997. RESULTS: During the past 5 years, a total of 53 cases of diverticulosis of the cecum and ascending colon had been treated at this hospital. Mean age was 41.8 years (range 20-70). The male to female ratio was 1.8 : 1. Frequent complaints were abdominal pain (46 cases, 86.8%), followed by diarrhea (5 cases, 9.3%), indigestion (4 cases, 7.5%), and bowel habits change (2 cases, 3.8%). Mean duration of illness was 3.5 days(range 24 hours~15 days). In non-surgical cases, diagnoses were established with barium enema, CT scan, or ultrasonography. The accuracy of these methods was 91%, 75%, and 25%. In surgical cases, the preoperative diagnoses were appendicitis(13 cases, 50.1%), diverticulitis (7 cases, 31.8%), and abscess (2 cases, 9.1%). Treatments of the cecum and ascending colon diverticulitis were conservative management (3 teases,58.5%) and surgical treatment (22 cases,41.5%). The operative procedures were right hemicolectomies (2 cases), ileocecal resections (2 cases), diverticulectomies (6 cases) and appendectomies only (11 cases). CONCLUSION: These results suggest that correct diagnosis of the diverticulitis of the cecum and ascending colon made before treatment is very important because correct assessment of diverticulitis intraoperatively is difacut. Liberal use of diagnostic modalities could facilitate to make correct diagnosis to set a proper plan for treatment.
Abdominal Pain
;
Abscess
;
Appendectomy
;
Barium
;
Cecum*
;
Colon, Ascending*
;
Diagnosis
;
Diarrhea
;
Diverticulitis
;
Diverticulum*
;
Dyspepsia
;
Enema
;
Female
;
Humans
;
Male
;
Rare Diseases
;
Surgical Procedures, Operative
;
Tomography, X-Ray Computed
;
Ultrasonography
9.Prevention of Allograft Rejection by Immune Tolerance.
Jong Soo LEE ; Byungsuk KWON ; Hong Rae CHO
The Journal of the Korean Society for Transplantation 2006;20(1):1-13
The development of immunosuprressants has had a significant contribution to inhibition of acute allograft rejection. However, long-term graft survival has not been realized by immunosuppressants, probably because of their nonspecific suppression of T cell activity and nonimmune side effects. The ideal way to overcome the limitations of current immunosuppressants is to induce allograft-specific immune tolerance. Transplant immunologists are exerting their efforts in achieving transplantation tolerance using three different approaches; mixed hematopoietic chimerism, costimulatory blockade, and regulation by regulatory T cells. It is expected that transplantation tolerance will soon be established as a standard immunosuppressive regimen with little side effects in preventing and reversing allograft rejection.
Allografts*
;
Chimerism
;
Graft Survival
;
Immune Tolerance*
;
Immunosuppressive Agents
;
T-Lymphocytes, Regulatory
;
Transplantation Tolerance
10.An Organized Chronic Subdural Hematoma with Partial Calcification in a Child.
Hyok Rae CHO ; Young KIM ; Hong Bo SIM ; In Uck LYO
Journal of Korean Neurosurgical Society 2005;37(5):386-388
The authors present a case in which an organized chronic subdural hematoma(CSDH) was incidentally found in a 9-year-old boy with no significant medical history after a pedestrian traffic accident. Preoperative magnetic resonance(MR) imaging showed calcification on the inner membrane and an irregular heterogeneous structure in the hematoma cavity. The findings from the preoperative brain computed tomogram(CT) and MR image were very useful for making the preoperative diagnosis and surgical decision. In choosing the proper surgical strategy for removing the organized CSDH, it was thought that burr hole trephination would present unnecessary difficulties. Thus, craniotomy was selected and the organized CSDH was successfully removed with no complications.
Accidents, Traffic
;
Brain
;
Child*
;
Craniotomy
;
Diagnosis
;
Hematoma
;
Hematoma, Subdural, Chronic*
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Membranes
;
Trephining