Objective To analyze the correlation of visual acuity and metamorphopsia with foveal morphology before and after vitrectomy with internal limiting membrane peeling (ILMP) in idiopathic macular epiretinal membrane (IMEM) eyes.Methods This is a retrospective case series of 47 IMEM patients (49 eyes).All the patients underwent 25G pars plana vitrectomy with IMEM removal and ILMP.The best corrected visual acuity (BCVA) was measured using the international standard visual acuity chart,and the results were converted to the logarithm of the minimum angle of resolution (logMAR) visual acuity.The severity of metamorphopsia was measured using M-charts.The central macular thickness (CMT),inner nuclear layer thickness (INT),inner retinal layer thickness (IRT),outer retinal layer thickness (ORT),the status of ellipsoid zone (EZ) were assessed with spectral-domain optical coherence tomography at baseline and each month postoperatively.The differences in BCVA,CMT,INT,IRT,ORT and status of EZ before and after surgery were analyzed,so did the correlations between these indexes at the same time.Results Compared with baseline,the postoperative BCVA was significantly increased (F=6.133,P＜0.001),but the M value,CMT,INT,IRT,ORT were significantly decreased (F=12.481,10.565,15.739,6.046,10.569;P＜0.001);the integrity of EZ was improved significantly (x2=12.309,P＜0.001).Preoperative BCVA was positively related to the CMT (r=0.720) and ORT (r=0.720,0.887;P＜0.05),while negatively related to preoperative integrity of EZ (r=-0.295,P＜0.05).The postoperative BCVA was positively related to the preoperative BCVA and postoperative CMT,ORT (r=0.774,0.754,0.842;P＜0.05),while negatively related to postoperative integrity of EZ (r=-0.676,P＜0.05).The preoperative M value was positively related to the preoperative CMT,INT,IRT,and ORT (r=0.931,0.668,0.840,0.637;P＜ 0.05).The postoperative M value was positively related to the preoperative M value and postoperative CMT,INT,IRT,and ORT (r=0.723,0.722,0.767,0.825,0.387;P＜0.05).Conclusions Vitrectomy with ILMP for IMEM can improve the visual acuity,metamorphopsia and foveal morphology.Both visual acuity and metamorphopsia correlate with foveal morphology.

Objective To evaluate the safety and effectiveness of vitrectomy combined with internal limiting membrane (ILM) tamping on macular hole and retinal detachment (MHRD) in highly myopic eyes.Methods 23 patients (23 eyes) were retrospectively reviewed,who were diagnosed as MHRD through examination of the ocular ftmdus,optic coherence tomography (OCT) and B-mode ultrasonography.There were 5 males (5 eyes) and 18 females (18 eyes).The mean age was (62.35 ± 8.28) years.The mean course of disease was 1.1 months.The logarithm of the minimum angle of resolution (logMAR) best-corrected visual acuity (BCVA) was 2.31 ± 0.72.The mean axial length was (28.66 ± 1.99) mm.All patients underwent 23G microincision vitrectomy.After vitreous gel and cortex were gently resected,the ILM around the edges of the macular hole was stained with indocyanine green,and was folded and pushed to fill the macular hole gently.Then silicone oil or C3F8 gas tamponade was applied in 18 eyes and 5 eyes,respectively.The silicone oil was removed after 3 months.The follow-up was 6 months.The BCVA,macular hole closure,retinal anatomical reattachment were retrospectively observed,and were used to evaluate the safety and effectiveness of the surgery.Results At the 6 months after surgery,the logMAR BCVA was improved to 1.13 ± 0.38,the difference was significant (t=l 5.33,P=0.00).The postoperative macular hole closure rate and retinal anatomical reattachment rate were 100％.There were no ocular or systemic adverse events observed in all patients.Conclusion Vitrectomy combined with ILM tamping is an effective and safe treatment for the high myopic eyes with MHRD.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.