2.Thinking about vertigo effectiveness evaluation methods in clinical research of Chinese medicine.
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(10):1256-1259
Vertigo is a kind of patients' subjective feelings. The severity of vertigo is closely related to many factors. But we are short of a well accepted quantitative evaluation method capable of accurately and comprehensively evaluating vertigo in clinics. Reducing the onset of vertigo, enhancing the re- covery of equilibrium function, and improving the quality of life of vertigo patients should be taken as the focus of evaluating therapeutic effects. As for establishing a Chinese medical effectiveness evaluation system for vertigo, we believe we should distinguish different "diseases". We could roughly identify it as systemic vertigo and non-systemic vertigo. For systemic vertigo, the efficacy of vertigo could be comprehensively evaluated by UCLA vertigo questionnaire or dizziness handicap inventory combined with equilibrium function testing indices. But for non-systemic vertigo, the efficacy of vertigo could be comprehensively evaluated by taking UCLA vertigo questionnaire or dizziness handicap inventory as main efficacy indices. Secondly, we should analyze different reasons for vertigo, choose symptoms and signs in line with vertigo features as well as with Chinese medical theories, and formulate corresponding syndrome effectiveness standards according to different diseases. We should not simply take syndrome diagnosis standards as efficacy evaluation standards.
China
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Dizziness
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diagnosis
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Humans
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Quality of Life
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Surveys and Questionnaires
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Vertigo
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diagnosis
5.Research Progress on Insect-resistant Genes From Plants
Hong-Mei CHEN ; Kun-Zhi LI ; Li-Mei CHEN ;
China Biotechnology 2006;0(11):-
Plant insect-resistantgenetic engineering hasopened a new way to prevent and cure against the insect pest incrop and wood productions. With the progresses instudies, many insect-resistantgeneswere cloned and characterized. The classification of most insect-resistantgenes from plant, the functionalmechanism and the applications of theplantinsect-resistantgenes, the problems and prospectsforusing the plant insect-resistant genes in genetic engineering was described.
6.A preliminary study of the relationship between Sema4A gene expression and Th cytokines in immune thrombocytopenia.
Hu ZHOU ; Hong-mei WANG ; Li MA
Chinese Journal of Hematology 2011;32(9):622-623
Adult
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Cytokines
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metabolism
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Female
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Gene Expression
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Humans
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Interleukin-2
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blood
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Interleukin-4
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blood
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Male
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Semaphorins
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genetics
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metabolism
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T-Lymphocytes, Helper-Inducer
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metabolism
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Thrombocytopenia
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genetics
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metabolism
7.Biomechanical study of percutaneous lumbar diskectomy
Yuan LI ; Shuizhong HONG ; Haiying MEI
Journal of Interventional Radiology 2001;0(05):-
Objective To investigate the stiffness of lumbar spine after the injury caused by percutaneous diskectomy and evaluate the efficiency of percutaneous lumbar diskectomy by biomechanical study. Methods Four fresh lumbar specimens were used to analyse load-displacement curves in the intact lumbar spine and vertical disc-injured lumbar spine. The concepts of average flexibility coefficient (f) and standardized average flexibility coefficient (fs) were also introduced. Results The load-displacement curves showed a good stabilization effect of the intact lumbar spine and disc-injured lumbar spine in flexion, extention, right and left bending. The decrease of anti-rotation also can be detected (P
9.Corticosteroid-induced severe glaucoma and posterior subcapsular cataract: a case report
International Eye Science 2009;9(9):1652-1654
Corticosteroid-induced glaucoma (CIG) is a form of open angle glaucoma associated with both topical and systemic administration of corticosteroids. Here we described the clinical findings in a patient with severe glaucoma and posterior subcapsular cataract (PSC) after topical administration of corticosteroid eye drops. We concluded corticosteroid eye drop was an effective medicine for inflammation of the eyes; however,prolonged use could cause severe vision loss as a result of intractable corticosteroid-induced glaucoma and cataract.
10.Clinical significance of VEGF-C and VEGFR-3 expression in non-small cell lung cancer.
Jun, LI ; Mei, HONG ; Tiecheng, PAN
Journal of Huazhong University of Science and Technology (Medical Sciences) 2006;26(5):587-90
The relationship between vascular endothelial growth factor-C (VEGF-C)/vascular endothelial growth factor receptor 3 (VEGFR-3) expression and clinicopathologic features of the patients with non-small cell lung cancer (NSCLC) was investigated. The expression of VEGF-C and VEGFR-3 was assessed in 65 patients with NSCLC by immunohistochemistry. The significance of VEGF-C and VEGFR-3 expression was analyzed statistically. The results showed that VEGF-C and VEGFR-3 were highly expressed in cytoplasm and membrane in lung cancer tissues with the positive rate being 55.4 % and 52.3 % respectively, while there was no expression in the normal lung tissues. The expression of VEGF-C was significantly increased in adenocacinoma as compared to other types of NSCLC (P<0.05). The VEGFR-3 expression was closely related with lymph node metastasis (P<0.01) and TNM stage (P<0.05). There was a positive correlation between the VEGF-C and VEGFR-3 expression in NSCLC patients (r=0.658, P<0.01). It is suggested that VEGFR-3 plays an important role in the lymphatic metastasis of NSCLC. The interaction between VEGF-C and VEGFR-3 may be deeply involved in the mechanism of lung cancer metastasis.