1.Study on lung compliance in normal subjects patients with obstructive or restrictive lung diseases.
Hong Lyeol LEE ; Sung Kyu KIM ; Won Young LEE
Korean Journal of Medicine 1993;45(2):200-212
No abstract available.
Humans
;
Lung Compliance*
;
Lung Diseases*
;
Lung*
2.Ga-67 SPECT Finding in Tuberculous Pericarditis with Mediastinal Mass: A case report.
Sung Eun KIM ; In Young HYUN ; Hong Lyeol LEE ; Hyung Jin KIM ; Won Sick CHOE
Korean Journal of Nuclear Medicine 2001;35(4):280-285
No abstract available.
Pericarditis, Tuberculous*
;
Tomography, Emission-Computed, Single-Photon*
3.Coagulation and Fibrinolysis in Exudative Peural Effusions.
Jeong Seon RYU ; Hong Lyeol LEE
Tuberculosis and Respiratory Diseases 1998;45(6):1214-1222
BACKGROUND: The intrapleural hypofibrinolysis is caused by mainly excessive concentration of pleural plasminogen ogen activator inhibitor-1 antigen(PAI-1 Ag), which binds tissue type plasminogen activator. In pleural inflammation induced by sclerosing agents for pleurodesis, levels of pleural PAI-1 antigen increase in relation to decreing D-dimer levels. It has been known that the pleural mexothelial cells have the capability of secreting PAI-1 Ag in response to inflammation in vivo. Therefore, we estimated whether pleural inflammation changes the balance between fibrinolytic and coagulative properties in exudative pleural effusions. METHOD: The thirty cases was included in our study. We determined the pleural levels of glucose, lactic dehy-drogenase(LDH), pH and the counts of white blood cell(WBC), polymorpho leukocyte(PMN), lymphocyte as the parameters of pleural inflammation and cellular components of pleural fluid. The plasma level of fibrinogen in fluid and the neutrophil count in blood were determined. The levels of D-dimer, PAI-1 Ag and thrombin-antithrombin lll complex(TAT) were determined by ELISA(Behring, Marburg, Germany). RESULTS: The causes of pleural effusion were as following : tuberculous in 14 cases, malignant in 10 cases and parapneumonic in 6 cases. The levels of pleural D-dimer, PAI-1 Ag and TAT was significantly higher than that of plasma(p<0.001). The severity of pleural inflammation did not correlated with pleural D-dimer, PAI-1 Ag, TAT and their plaxma levels. But the level of pleural TAT correlated with pleural WBC and lymphocyte count. CONCLUSION: We found the the severity of pleural inflammations did not correlated with pleural D-dimer, PAI-1 Ag, TAT and the possibility of local production of PAI-1 antigen is present.
Fibrinogen
;
Fibrinolysis*
;
Glucose
;
Hydrogen-Ion Concentration
;
Inflammation
;
Lymphocyte Count
;
Lymphocytes
;
Neutrophils
;
Plasma
;
Plasminogen
;
Plasminogen Activator Inhibitor 1
;
Pleural Effusion
;
Pleurodesis
;
Sclerosing Solutions
;
Tissue Plasminogen Activator
4.A case of percutaneous intracavitary amphotericin B instillation for the treatment of hemoptysis due to pulmonary aspergilloma.
Hong Lyeol LEE ; Hong Keun CHO ; Se Kyu KIM ; Joon CHANG ; Sung Kyu KIM ; Won Young LEE ; Kyu Ok CHOE
Tuberculosis and Respiratory Diseases 1992;39(2):180-185
No abstract available.
Amphotericin B*
;
Hemoptysis*
5.A clinical study on bone marrow necrosis.
Jee Sook HAHN ; Hong Lyeol LEE ; Sun Ju LEE ; Yoo Hong MIN ; Yun Woong KO ; Woo Ik YANG
Korean Journal of Hematology 1991;26(1):135-149
No abstract available.
Bone Marrow*
;
Necrosis*
6.The Diagnostic Value of Isocapnic Hyperventilation of Cold Air in Adults with Suspected Asthma.
Jae Hwa CHO ; Jwong Swon RYU ; Ji Young LEE ; Seung Min KWAK ; Hong Lyeol LEE ; Chul Ho CHO
Tuberculosis and Respiratory Diseases 2001;51(3):232-239
BACKGROUND: Asthmatic patients frequently suffer cold-weather-associated respiratory symptoms. The sensitivity, specificity, accuracy and diagnostic value of isocapnic hyperventilation of cold air(IHCA) using a multistep method was investigated in patients suspected to have asthma. METHOD: One hundred and 29 adult patients who had an IHCA performed between july 1999 and December 2000, had an methacholine bronchoprovocation test because of a clinical suspicion of asthma. RESULTS: According to strict criteria, 50 were defined as asthmatics and 79 as symptomatic nonashmatics. There were no differences in age, sex and smoking state between the asthmatic and symptomatic nonasthmatic groups. There was a significant decrease in the percentage reduction in the forced expiratory volume in 1 second(FEV1) after the IHCA between the asthmatics(-10.0±6.8%) and the symptomatic nonasthmatics(-2.3±2.5%). The factors associated with a reactivity to IHCA were FEV1/FVC, FEF25-75/FVC and FEV1(% of predicted). The accuracy was highest using a 7% fall in FEV1; the sensitivity was 76% and the specificity 96%. CONCLUSION: IHCA is a specific, although not a sensitive, test for diagnosing asthma in adult patients. Furthermore, the diagnostic cut-off value of the different methods of IHCA need to be determined.
Adult*
;
Asthma*
;
Forced Expiratory Volume
;
Humans
;
Hyperventilation*
;
Methacholine Chloride
;
Sensitivity and Specificity
;
Smoke
;
Smoking
7.Three Cases of Gastric Pseudolymphoma.
Hong Lyeol LEE ; Si Young SONG ; Won Ho KIM ; Sang Il LEE ; In Suh PARK ; Heung Jai CHOI
Korean Journal of Gastrointestinal Endoscopy 1989;9(2):187-193
Gastric pseudolymphoma can be defined as a benign proliferation of lymphoid tissue and is also called the lymphoid hyperplasia or reactive lymphoreticular hyperplasia of the stomach. This lesion has been described in the orbital area, skin, salivary glands, mediastinum and other organs. The etiology of this disease is unknown but chronic inflammation and ulceration have been proposed as the etiologic mechanism in many cases. Most patients exhibit chronic, nonspecific, mild symptoms with the vast majority having symptoms for more than 1 year before undergoing diagnosis and treatment. Unfortunately, upper GI radiography rarely clarifies the diagnosis and gastroacopy is ineffective in establishing the diagnosis of pseudolpnphoma. Therefare, gastric resection is the only sure way to diagnose gastric pseudolympboma, as well as providing curitive therapy in most cases because of its possible malignant potential. There is no typical gross appearance of gastric pseudolymphoma and histologic diagoosis is essential. Smaller tumor size, infiltration with small, round mature lymphoeytos and various inflammatory cells, and formation of a true lymphoid germinal center favor a diagnosis of pseudolymphoma, We report 3 cases of histopathologically confirmed gastric pseudolymphoma after gastrectomy, which were initially suspected to be gastric lymphoma and early gastric cancer
Diagnosis
;
Gastrectomy
;
Germinal Center
;
Humans
;
Hyperplasia
;
Inflammation
;
Lymphoid Tissue
;
Lymphoma
;
Mediastinum
;
Orbit
;
Pseudolymphoma*
;
Radiography
;
Salivary Glands
;
Skin
;
Stomach
;
Stomach Neoplasms
;
Ulcer
8.A study on the early prediction of prognosis in mechanically ventilated patients due to acute respiratory failure.
Hong Lyeol LEE ; Se Kyu KIM ; Joon CHANG ; Hyung Kil KIM ; Sung Kyu KIM ; Won Young LEE ; Jin Ho KIM
Korean Journal of Medicine 1993;45(6):713-725
No abstract available.
Humans
;
Prognosis*
;
Respiratory Insufficiency*
9.Chronic cough: the spectrum and the frequency of etiologies.
Jae Hwa CHO ; Jeong Seon RYU ; Hong Lyeol LEE
Tuberculosis and Respiratory Diseases 1999;46(4):555-563
BACKGROUND: Chronic cough is a common symptom that requires the systematic diagnostic approach for proper evaluation. Postnasal drip syndrome(PNDS), bronchial asthma, gastroesophageal reflux disease(GERD), and chronic bronchitis are among the common causes. This study was conducted to evaluate the spectrum and the frequency of the causes of chronic cough. METHODS: We prospectively evaluated 93 patients who had chronic cough despite normal chest radiographic finding. History and physical examination were done along with paranasal sinus radiograph, spirometry, bronchoprovocation test and 24-hours' ambulatory aesophageal pH monitoring as necessary. RESULTS: Forty-nine(52%) of the 93 patients had PNDS, 15 patients(16%) bronchitis, 10 patients(11%) asthma, 4 patients(4%) GERD, 7 patients(8%) both PNDS and asthma, 4 patients(4%) undiagnosed condition and 4 patients(4%) were taking ACE inhibitor. Sixty-nine percent of the patients with PNDS improved after follow up, 73% patients with bronchitis, 80% patients with asthma, 50% patients with GERD, 100% patients with both PNDS and asthma, and 100% patients with ACE inhibitor. CONCLUSION: PNDS was the most common causes of chronic cough. Bronchitis was the second and asthma the third in frequency. The etiology of chronic cough can be determined easily by history and physical examination, successful therapy initiated in most patients. The response to specific therapy also was important in evaluation of chronic cough.
Asthma
;
Bronchitis
;
Bronchitis, Chronic
;
Cough*
;
Diagnosis
;
Follow-Up Studies
;
Gastroesophageal Reflux
;
Humans
;
Hydrogen-Ion Concentration
;
Physical Examination
;
Prospective Studies
;
Radiography, Thoracic
;
Spirometry
10.Chronic cough: the spectrum and the frequency of etiologies.
Jae Hwa CHO ; Jeong Seon RYU ; Hong Lyeol LEE
Tuberculosis and Respiratory Diseases 1999;46(4):555-563
BACKGROUND: Chronic cough is a common symptom that requires the systematic diagnostic approach for proper evaluation. Postnasal drip syndrome(PNDS), bronchial asthma, gastroesophageal reflux disease(GERD), and chronic bronchitis are among the common causes. This study was conducted to evaluate the spectrum and the frequency of the causes of chronic cough. METHODS: We prospectively evaluated 93 patients who had chronic cough despite normal chest radiographic finding. History and physical examination were done along with paranasal sinus radiograph, spirometry, bronchoprovocation test and 24-hours' ambulatory aesophageal pH monitoring as necessary. RESULTS: Forty-nine(52%) of the 93 patients had PNDS, 15 patients(16%) bronchitis, 10 patients(11%) asthma, 4 patients(4%) GERD, 7 patients(8%) both PNDS and asthma, 4 patients(4%) undiagnosed condition and 4 patients(4%) were taking ACE inhibitor. Sixty-nine percent of the patients with PNDS improved after follow up, 73% patients with bronchitis, 80% patients with asthma, 50% patients with GERD, 100% patients with both PNDS and asthma, and 100% patients with ACE inhibitor. CONCLUSION: PNDS was the most common causes of chronic cough. Bronchitis was the second and asthma the third in frequency. The etiology of chronic cough can be determined easily by history and physical examination, successful therapy initiated in most patients. The response to specific therapy also was important in evaluation of chronic cough.
Asthma
;
Bronchitis
;
Bronchitis, Chronic
;
Cough*
;
Diagnosis
;
Follow-Up Studies
;
Gastroesophageal Reflux
;
Humans
;
Hydrogen-Ion Concentration
;
Physical Examination
;
Prospective Studies
;
Radiography, Thoracic
;
Spirometry