1.Clinical effect and safety of modified small incision in the treatment of soft-cataract
International Eye Science 2017;17(7):1337-1339
AIM:To investigate the effect and safety of modified small incision cataract surgery in patients with soft core cataract.METHODS: Totally 80 cases (109 eyes) of soft cataract patients who underwent surgical treatment from January 2015 to May 2016 in ophthalmology center of our hospital, using random number table method were divided into improved group (improved manipulation of small incision cataract surgery), traditional group (traditional approach to small incision cataract surgery), 40 cases in each group.Comparison of the two groups of treatment, the incidence of complications were taken.RESULTS: There were no significant differences on uncorrected visual acuity between the two groups before and at 1d, 1wk and 1mo after operations (P>0.05).The uncorrected visual acuity of the two groups improved significantly at 1d, 1wk and 1mo after operations compared with those before operations (P<0.05).There were no significant differences on intraocular pressure(IOP) between the two groups before and at 1d, 1wk and 1mo after operations (P>0.05).The IOP of the two groups increased significantly at 1d, 1wk and 1mo after operations compared with those before operations (P<0.05).The complication rate was 9% (5/54) in the modified group, significantly lower than that in the conventional group 25% (14/55) (P<0.05).CONCLUSION: Improved small incision cataract surgery for soft cataract patients was with reliable results, less complications.
2.Study on the processing of silk biomaterial and its application in tissue engineering
International Journal of Biomedical Engineering 2008;31(3):188-191
Silk fiber,as a kind of natural polymer,has been used as surgical sutures in clinic for years.Silk fiber is composed of a filament core protein,termed fibroin and a glue-like coating called sericin proteins.Due to its unique mechanical properties,good biocompatibility and slow degradability,silk fiber has been put in variety of applications as a new kind of biomedical scaffolds in recent years.With the development of the processing technique,silk fiber can be processed through the new versatile processing method to form various forms of scaffolds and its surface could be modified for different purposes.Further more,it could be tailored through genetic recombination to form the silk fibroin-like polymers which has a promising potential in medical applications.
3.Obstructive sleep-disordered breathing in infants.
Xiao-hong CAI ; Liang-xing WANG
Chinese Journal of Pediatrics 2013;51(10):753-755
Continuous Positive Airway Pressure
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Facial Bones
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abnormalities
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Humans
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Infant
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Larynx
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pathology
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Oxygen Inhalation Therapy
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Pharynx
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pathology
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Polysomnography
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Respiration
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Risk Factors
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Sleep Apnea Syndromes
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diagnosis
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etiology
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therapy
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Sleep Apnea, Obstructive
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diagnosis
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etiology
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therapy
4.Discovery and biology of Schistosoma haematobium
Wei WANG ; Qingbiao HONG ; Yousheng LIANG
Chinese Journal of Schistosomiasis Control 2014;(2):215-218
Schistosomiasis is a neglected tropical disease that severely threatens human health and affects the socioeconomic development. The causative agent that parasitizes in humans mainly involves Schistosoma japonicum,S. mansoni,S. haematobi-um,S. intercalatum and S. mekongi. As the firstly identified schistosome,S. haematobium infection is found to strongly correlate with bladder cancer. This paper mainly reviews the discovery,morphology and life cycle of S. haematobium.
5.Diagnostic tests for thyroid function and disorders.
Yan LIANG ; Hong WEI ; Mu-ti WANG
Chinese Journal of Pediatrics 2006;44(9):662-665
6.A case of Beckwith-Wiedemann syndrome.
Hong LIANG ; Qing-jie WANG ; Jing CHEN
Chinese Journal of Pediatrics 2005;43(12):945-946
7.Screening for genes related to novel gene AngRem104 by gene chip
Xiubin LIANG ; Hong ZHANG ; Haiyan WANG
Chinese Journal of Nephrology 1997;0(03):-
Objective To screen the genes related to novel gene AngReml04. Methods Gene chip was employed to detect the genes related to AngRem104 by its over-expressed constructs, which was produced by transfection of the sense- and antisense-AngReml04 into human mesangial cells, and then RT-PCR was used to confirm the up-regulated expression of related genes. Results There were 94 genes up-regulated and 2 genes down-regulated when AngRem104 was over-expression. The different expression genes were cataloged as extracellular matrix and receptor protein, DNA-binding and transcription-related protein, immune-related protein, cytoskeletal and dynamic protein, synthesis and metabolism related protein. Fibronectin (FN) and integrin beta 1 (fibronectin receptor) were dramatically over-expressed in the top of all up-regulated genes. Furthermore, the correlative expression between AngReml04 and FN was detected by RT-PCR. Conclusion Gene chip not only demonstrates the clues for further investigation of novel gene AngRem 104, but also reveals the co-expression of AngRem104 and fibronectin.
9.Functional examination of growth hormone-insulin-like growth factor axis in short stature children.
Hong WEI ; Yan LIANG ; Mu-ti WANG
Chinese Journal of Pediatrics 2005;43(2):99-103
Body Height
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Child
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Female
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Ghrelin
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pharmacology
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Growth Disorders
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physiopathology
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Growth Hormone-Releasing Hormone
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pharmacology
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Human Growth Hormone
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blood
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physiology
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urine
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Humans
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Insulin-Like Growth Factor Binding Protein 3
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blood
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Insulin-Like Growth Factor I
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physiology
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Male
10.Effect of astragaloside Ⅳ on contraction and relaxation in isolated rat aortic rings
Xuhui WANG ; Liang ZHU ; Hong CHEN
Chinese Pharmacological Bulletin 2003;0(11):-
Aim To study the effect and investigate the underlying mechanism of astragaloside Ⅳ on contraction and relaxation in isolated rat aortic rings.Methods The relaxation effect of astragaloside Ⅳ(1~100 mg?L~(-1))on phenylephrine-preconstricted aorta ring was recorded.The effect of astragaloside Ⅳ on the contraction induced by cumulative phenylephrine,KCl or CaCl_2,was recorded respectively.Results Astragaloside Ⅳ dilated aortic vessels in a dose-dependent manner,which was partly inhibited by preincubation with non-selective nitric oxide synthase inhibitor,guanylyl cyclase inhibitor and cyclooxygenases inhibitor indomethacin.Astragaloside IV could also antagonize phenylephrine-,KCl-and CaCl_2-induced vessel contraction.Conclusion Astragaloside IV dilated aortic vessels partially though endothelium-dependent NO pathway and inhibited vessel contraction via interfering Ca~(2+) influx.